Donna L McPhie

Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophrenia.

Nat Neurosci 2020 11 23;23(11):1352-1364. Epub 2020 Oct 23.

Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA.

November 2020

Correction: iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function.

Authors:

Peiyan Ni Haneul Noh Gun-Hoo Park Zhicheng Shao Youxin Guan James M Park Sophy Yu Joy S Park Joseph T Coyle Daniel R Weinberger Richard E Straub Bruce M Cohen Donna L McPhie Changhong Yin Weihua Huang Hae-Young Kim Sangmi Chung

Mol Psychiatry 2020 Nov;25(11):3103-3104

Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, 10595, USA.

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November 2020

iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function.

Authors:

Peiyan Ni Haneul Noh Gun-Hoo Park Zhicheng Shao Youxin Guan James M Park Sophy Yu Joy S Park Joseph T Coyle Daniel R Weinberger Richard E Straub Bruce M Cohen Donna L McPhie Changhong Yin Weihua Huang Hae-Young Kim Sangmi Chung

Mol Psychiatry 2020 11 24;25(11):2873-2888. Epub 2019 Apr 24.

Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, 10595, USA.

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November 2020

Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia.

Nat Neurosci 2019 02 21;22(2):229-242. Epub 2019 Jan 21.

Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.

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February 2019

Oligodendrocyte differentiation of induced pluripotent stem cells derived from subjects with schizophrenias implicate abnormalities in development.

Authors:

Donna L McPhie Ralda Nehme Caitlin Ravichandran Suzann M Babb Sulagna Dia Ghosh Alexandra Staskus Amy Kalinowski Rupinderjit Kaur Panagiotis Douvaras Fei Du Dost Ongur Valentina Fossati Kevin Eggan Bruce M Cohen

Transl Psychiatry 2018 10 23;8(1):230. Epub 2018 Oct 23.

Harvard Medical School, Boston, MA, USA.

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October 2018

Late-onset Alzheimer's disease is associated with inherent changes in bioenergetics profiles.

Authors:

Kai-C Sonntag Woo-In Ryu Kristopher M Amirault Ryan A Healy Arthur J Siegel Donna L McPhie Brent Forester Bruce M Cohen

Sci Rep 2017 10 25;7(1):14038. Epub 2017 Oct 25.

Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA.

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October 2017

Hardware Technologies and Probe Development in Light Microscopy Help Drive Discoveries in Cell Biology: Introduction to a Virtual Symposium in The Biological Bulletin.

Authors:

Lisa A Cameron Donna L McPhie

Biol Bull 2016 Aug;231(1):2-4

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August 2016

Hardware Technologies and Probe Development in Light Microscopy Help Drive Discoveries in Cell Biology: Introduction to a Virtual Symposium in The Biological Bulletin.

Authors:

Lisa A Cameron Donna L McPhie

Biol Bull 2016 08;231(1):3-4

Cellular Neuropsychiatry Laboratory, McLean Hospital, Harvard Medical School and Harvard University, Belmont, Massachusetts 02478.

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August 2016

Sprouty2 in the dorsal hippocampus regulates neurogenesis and stress responsiveness in rats.

Authors:

Antonia L Dow Tiffany V Lin Elena H Chartoff David Potter Donna L McPhie Ashlee V Van't Veer Allison T Knoll Kristen N Lee Rachael L Neve Tarun B Patel Dost Ongur Bruce M Cohen William A Carlezon

PLoS One 2015 30;10(3):e0120693. Epub 2015 Mar 30.

Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, Massachusetts, United States of America.

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March 2016

MiR-126 Regulates Growth Factor Activities and Vulnerability to Toxic Insult in Neurons.

Authors:

Woori Kim Haneul Noh Yenarae Lee Jeha Jeon Arthi Shanmugavadivu Donna L McPhie Kwang-Soo Kim Bruce M Cohen Hyemyung Seo Kai C Sonntag

Mol Neurobiol 2016 Jan 19;53(1):95-108. Epub 2014 Nov 19.

Department of Psychiatry, McLean Hospital, Harvard Medical School, MRC 223, 115 Mill Street, Belmont, MA, 02478, USA.

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January 2016

Abnormalities in mitochondrial structure in cells from patients with bipolar disorder.

Authors:

Anne M Cataldo Donna L McPhie Nicholas T Lange Steven Punzell Sarah Elmiligy Nancy Z Ye Michael P Froimowitz Linda C Hassinger Emily B Menesale Laura W Sargent David J Logan Anne E Carpenter Bruce M Cohen

Am J Pathol 2010 Aug 21;177(2):575-85. Epub 2010 Jun 21.

Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.

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August 2010

Rab5 mediates an amyloid precursor protein signaling pathway that leads to apoptosis.

Authors:

Daphna Laifenfeld Lucas J Patzek Donna L McPhie Yuzhi Chen Yona Levites Anne M Cataldo Rachael L Neve

J Neurosci 2007 Jul;27(27):7141-53

Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, Massachusetts 02478, USA.

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July 2007

APP-BP1 inhibits Abeta42 levels by interacting with Presenilin-1.

Authors:

Yuzhi Chen Angela M Bodles Donna L McPhie Rachael L Neve Robert E Mrak W Sue T Griffin

Mol Neurodegener 2007 Feb 7;2. Epub 2007 Feb 7.

Department of Geriatrics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

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February 2007

Dysfunction of amyloid precursor protein signaling in neurons leads to DNA synthesis and apoptosis.

Authors:

Rachael L Neve Donna L McPhie

Biochim Biophys Acta 2007 Apr 18;1772(4):430-7. Epub 2006 Oct 18.

Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA 02478, USA.

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April 2007

Biological Bulletin Virtual Symposium: Marine Invertebrate Models of Learning and Memory.

Authors:

Donna L McPhie Mark W Miller

Biol Bull 2006 Jun;210(3):171-173

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June 2006

The cell cycle as a therapeutic target for Alzheimer's disease.

Authors:

Rachael L Neve Donna L McPhie

Pharmacol Ther 2006 Jul 7;111(1):99-113. Epub 2005 Nov 7.

Department of Psychiatry, MRC 223, Harvard Medical School and McLean Hospital, Belmont, MA 02478, USA.

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July 2006

APP-BP1 mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brain.

Authors:

Yuzhi Chen Wenyun Liu Donna L McPhie Linda Hassinger Rachael L Neve

J Cell Biol 2003 Oct;163(1):27-33

MRC 223, McLean Hospital, 115 Mill St., Belmont, MA 02478, USA.

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October 2003

DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3.

Authors:

Donna L McPhie Robert Coopersmith Andrew Hines-Peralta Yuzhi Chen Kathryn J Ivins Susan P Manly Michael R Kozlowski Kim A Neve Rachael L Neve

J Neurosci 2003 Jul;23(17):6914-27

Department of Psychiatry, Harvard Medical School and McLean Hospital, Belmont, Massachusetts 02478, USA.

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July 2003

Abeta42 generation is toxic to endothelial cells and inhibits eNOS function through an Akt/GSK-3beta signaling-dependent mechanism.

Authors:

Toshimitsu Suhara Jordi Magrané Kenneth Rosen Rial Christensen Hyo-Soo Kim Bing Zheng Donna L McPhie Kenneth Walsh Henry Querfurth

Neurobiol Aging 2003 May-Jun;24(3):437-51

Divisions of Neurology and Cardiovascular Research, St Elizabeth's Medical Center, Tufts University, Boston, MA 02135, USA.

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April 2003

Publications by authors named "Donna L McPhie"

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