Dong Ho Han

Dong Ho Han

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Dong Ho Han

Dong Ho Han

Publications by authors named "Dong Ho Han"

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AMPK and PPARβ positive feedback loop regulates endurance exercise training-mediated GLUT4 expression in skeletal muscle.

Am J Physiol Endocrinol Metab 2019 05 19;316(5):E931-E939. Epub 2019 Mar 19.

Department of Health Sciences Research, Mayo Clinic , Rochester, Minnesota.

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http://dx.doi.org/10.1152/ajpendo.00460.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580175PMC
May 2019

PPARβ Is Essential for Maintaining Normal Levels of PGC-1α and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise.

Cell Metab 2017 May;25(5):1176-1185.e5

Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.cmet.2017.04.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894349PMC
May 2017

PGC-1α mediates a rapid, exercise-induced downregulation of glycogenolysis in rat skeletal muscle.

J Physiol 2015 Feb 23;593(3):635-43. Epub 2014 Dec 23.

Division of Geriatrics and Nutritional Sciences, Section of Applied Physiology, Department of Medicine, Washington University School of Medicine, 4566 Scott Avenue, Campus Box 8113, St Louis, MO, 63110, USA.

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http://dx.doi.org/10.1113/jphysiol.2014.283820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324710PMC
February 2015

Effects of resveratrol and SIRT1 on PGC-1α activity and mitochondrial biogenesis: a reevaluation.

PLoS Biol 2013 Jul 9;11(7):e1001603. Epub 2013 Jul 9.

Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington University School of Medicine in St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.1001603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706311PMC
July 2013

β-Adrenergic stimulation does not activate p38 MAP kinase or induce PGC-1α in skeletal muscle.

Am J Physiol Endocrinol Metab 2013 Apr 26;304(8):E844-52. Epub 2013 Feb 26.

Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00581.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625780PMC
April 2013

Ginsenoside Re rapidly reverses insulin resistance in muscles of high-fat diet fed rats.

Metabolism 2012 Nov 8;61(11):1615-21. Epub 2012 May 8.

Department of Medicine, Center for Human Nutrition, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.metabol.2012.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426645PMC
November 2012

The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2.

Genes Dev 2011 Dec 1;25(24):2619-30. Epub 2011 Dec 1.

Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, Orlando, Florida 32827, USA.

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http://dx.doi.org/10.1101/gad.178434.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248683PMC
December 2011

Normal adaptations to exercise despite protection against oxidative stress.

Am J Physiol Endocrinol Metab 2011 Nov 12;301(5):E779-84. Epub 2011 Jul 12.

Division of Geriatrics and Nutritional Sciences, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00655.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214004PMC
November 2011

Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans.

Aging (Albany NY) 2011 May;3(5):533-42

Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156603PMC
http://dx.doi.org/10.18632/aging.100327DOI Listing
May 2011

Deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance.

PLoS One 2011 May 12;6(5):e19739. Epub 2011 May 12.

Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington University School of Medicine, Saint Louis, Missouri, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019739PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093385PMC
May 2011

Does calorie restriction induce mitochondrial biogenesis? A reevaluation.

FASEB J 2011 Feb 3;25(2):785-91. Epub 2010 Nov 3.

Washington University School of Medicine, Division of Geriatrics and Nutritional Sciences, 4566 Scott Ave., Campus Box 8113, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1096/fj.10-170415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023396PMC
February 2011

Is "fat-induced" muscle insulin resistance rapidly reversible?

Am J Physiol Endocrinol Metab 2009 Jul 12;297(1):E236-41. Epub 2009 May 12.

Department of Internal Medicine, Washington University School of Medicine, 4566 Scott Ave., Campus Box 8113, St. Louis, MO 63110, USA.

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http://www.physiology.org/doi/10.1152/ajpendo.00244.2009
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http://dx.doi.org/10.1152/ajpendo.00244.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711661PMC
July 2009

High-fat diets cause insulin resistance despite an increase in muscle mitochondria.

Proc Natl Acad Sci U S A 2008 Jun 28;105(22):7815-20. Epub 2008 May 28.

Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.

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http://dx.doi.org/10.1073/pnas.0802057105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409421PMC
June 2008

A role for the transcriptional coactivator PGC-1alpha in muscle refueling.

J Biol Chem 2007 Dec 11;282(50):36642-51. Epub 2007 Oct 11.

Center for Cardiovascular Research, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M707006200DOI Listing
December 2007

IL-6 increases muscle insulin sensitivity only at superphysiological levels.

Am J Physiol Endocrinol Metab 2007 Jun 27;292(6):E1842-6. Epub 2007 Feb 27.

Division of Geriatrics and Nutritional Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00701.2006DOI Listing
June 2007

PET measurements of myocardial glucose metabolism with 1-11C-glucose and kinetic modeling.

J Nucl Med 2007 Jun;48(6):955-64

Division of Radiological Sciences, Edward Mallinckrodt Institute of Radiology, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.2967/jnumed.106.037598DOI Listing
June 2007

Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle.

Proc Natl Acad Sci U S A 2007 Jun 4;104(25):10709-13. Epub 2007 Jun 4.

Division of Geriatrics and Nutritional Science, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1073/pnas.0704024104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1965577PMC
June 2007

Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1alpha expression.

J Biol Chem 2007 Jan 12;282(1):194-9. Epub 2006 Nov 12.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M606116200DOI Listing
January 2007

How muscle insulin sensitivity is regulated: testing of a hypothesis.

Am J Physiol Endocrinol Metab 2006 Dec 11;291(6):E1258-63. Epub 2006 Jul 11.

Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00273.2006DOI Listing
December 2006

Inhibition of calpain results in impaired contraction-stimulated GLUT4 translocation in skeletal muscle.

Am J Physiol Endocrinol Metab 2006 Sep 16;291(3):E544-8. Epub 2006 May 16.

Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00510.2005DOI Listing
September 2006

PPARdelta activator GW-501516 has no acute effect on glucose transport in skeletal muscle.

Am J Physiol Endocrinol Metab 2006 Apr 8;290(4):E607-11. Epub 2005 Nov 8.

Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00430.2005DOI Listing
April 2006

Are tyrosine kinases involved in mediating contraction-stimulated muscle glucose transport?

Am J Physiol Endocrinol Metab 2006 Jan 13;290(1):E123-E128. Epub 2005 Sep 13.

Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00280.2005DOI Listing
January 2006

Contraction- and hypoxia-stimulated glucose transport is mediated by a Ca2+-dependent mechanism in slow-twitch rat soleus muscle.

Am J Physiol Endocrinol Metab 2005 Jun 18;288(6):E1062-6. Epub 2005 Jan 18.

Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington Univ. School of Medicine, Applied Physiology, Campus Box 8113, 4566 Scott Ave., St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00561.2004DOI Listing
June 2005

Activation of p38 MAP kinase enhances sensitivity of muscle glucose transport to insulin.

Am J Physiol Endocrinol Metab 2005 Apr 7;288(4):E782-8. Epub 2004 Dec 7.

Departemnt of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00477.2004DOI Listing
April 2005

Calcineurin does not mediate exercise-induced increase in muscle GLUT4.

Diabetes 2005 Mar;54(3):624-8

Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.2337/diabetes.54.3.624DOI Listing
March 2005

A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes.

Cell Metab 2005 Feb;1(2):133-44

Center for Cardiovascular Research, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1016/j.cmet.2005.01.006DOI Listing
February 2005

Phorbol esters affect skeletal muscle glucose transport in a fiber type-specific manner.

Am J Physiol Endocrinol Metab 2004 Aug 30;287(2):E305-9. Epub 2004 Mar 30.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00082.2004DOI Listing
August 2004

Calpain system regulates muscle mass and glucose transporter GLUT4 turnover.

J Biol Chem 2004 May 9;279(20):20915-20. Epub 2004 Mar 9.

Department of Medicine, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1074/jbc.M400213200DOI Listing
May 2004

UCP-mediated energy depletion in skeletal muscle increases glucose transport despite lipid accumulation and mitochondrial dysfunction.

Am J Physiol Endocrinol Metab 2004 Mar 12;286(3):E347-53. Epub 2003 Nov 12.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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https://www.researchgate.net/profile/Dong_Ho_Han/publication
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http://www.physiology.org/doi/10.1152/ajpendo.00434.2003
Publisher Site
http://dx.doi.org/10.1152/ajpendo.00434.2003DOI Listing
March 2004

Ca2+ and AMPK both mediate stimulation of glucose transport by muscle contractions.

Diabetes 2004 Feb;53(2):330-5

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.2337/diabetes.53.2.330DOI Listing
February 2004

Glucosamine and glucose induce insulin resistance by different mechanisms in rat skeletal muscle.

Am J Physiol Endocrinol Metab 2003 Dec 3;285(6):E1267-72. Epub 2003 Sep 3.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00255.2003DOI Listing
December 2003

Prevention of glycogen supercompensation prolongs the increase in muscle GLUT4 after exercise.

Am J Physiol Endocrinol Metab 2003 Oct 10;285(4):E729-36. Epub 2003 Jun 10.

Department of Internal Medicine, Washington University School of Medicine, 4566 Scott Avenue, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00216.2003DOI Listing
October 2003

Skeletal muscle overexpression of nuclear respiratory factor 1 increases glucose transport capacity.

FASEB J 2003 Sep;17(12):1666-73

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1096/fj.03-0049comDOI Listing
September 2003

A peroxovanadium compound stimulates muscle glucose transport as powerfully as insulin and contractions combined.

Diabetes 2003 Aug;52(8):1918-25

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.2337/diabetes.52.8.1918DOI Listing
August 2003

Raising Ca2+ in L6 myotubes mimics effects of exercise on mitochondrial biogenesis in muscle.

FASEB J 2003 Apr;17(6):675-81

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1096/fj.02-0951comDOI Listing
April 2003

Intermittent increases in cytosolic Ca2+ stimulate mitochondrial biogenesis in muscle cells.

Am J Physiol Endocrinol Metab 2002 Nov;283(5):E1040-5

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00242.2002DOI Listing
November 2002

Glucose transport rate and glycogen synthase activity both limit skeletal muscle glycogen accumulation.

Am J Physiol Endocrinol Metab 2002 Jun;282(6):E1214-21

Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.00254.2001DOI Listing
June 2002

Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin.

Am J Physiol Endocrinol Metab 2002 Jan;282(1):E18-23

Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1152/ajpendo.2002.282.1.E18DOI Listing
January 2002