Publications by authors named "Donald M McDonald"

100Publications

Lymphatic Proliferation Ameliorates Pulmonary Fibrosis after Lung Injury.

Am J Pathol 2020 Oct 8. Epub 2020 Oct 8.

Department of Anatomy, University of California, San Francisco, San Francisco, California; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2020.08.018DOI Listing
October 2020

Imaging Lymphatics in Mouse Lungs.

Methods Mol Biol 2018 ;1846:161-180

Department of Anatomy, Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute, University of California, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-8712-2_11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501193PMC
May 2019

Tighter lymphatic junctions prevent obesity.

Science 2018 08;361(6402):551-552

Department of Anatomy, University of California, San Francisco, CA 94143-0452, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aau5583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532637PMC
August 2018

Amplification of Oncolytic Vaccinia Virus Widespread Tumor Cell Killing by Sunitinib through Multiple Mechanisms.

Cancer Res 2018 02 19;78(4):922-937. Epub 2017 Dec 19.

UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, San Francisco, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-15-3308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501576PMC
February 2018

The protective role of sphingosine-1-phosphate against the action of the vascular disrupting agent combretastatin A-4 3--phosphate.

Oncotarget 2017 Nov 21;8(56):95648-95661. Epub 2017 Sep 21.

Tumour Microcirculation Group, The University of Sheffield, Department of Oncology and Metabolism, School of Medicine, Sheffield, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.21172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707050PMC
November 2017

Rapamycin reversal of VEGF-C-driven lymphatic anomalies in the respiratory tract.

JCI Insight 2017 Aug 17;2(16). Epub 2017 Aug 17.

Cardiovascular Research Institute, Department of Anatomy, and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/jci.insight.90103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621869PMC
August 2017

Retrograde Lymph Flow Leads to Chylothorax in Transgenic Mice with Lymphatic Malformations.

Am J Pathol 2017 Sep 3;187(9):1984-1997. Epub 2017 Jul 3.

Department of Anatomy, Cardiovascular Research Institute, and UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2017.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808174PMC
September 2017

Anti-metastatic action of FAK inhibitor OXA-11 in combination with VEGFR-2 signaling blockade in pancreatic neuroendocrine tumors.

Clin Exp Metastasis 2015 Dec 7;32(8):799-817. Epub 2015 Oct 7.

UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute, and Department of Anatomy, University of California - San Francisco, 513 Parnassus Avenue, Room S1349, San Francisco, CA, 94143-0452, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10585-015-9752-z
Publisher Site
http://dx.doi.org/10.1007/s10585-015-9752-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651821PMC
December 2015

Synergistic actions of blocking angiopoietin-2 and tumor necrosis factor-α in suppressing remodeling of blood vessels and lymphatics in airway inflammation.

Am J Pathol 2015 Nov 5;185(11):2949-68. Epub 2015 Sep 5.

Department of Anatomy, Cardiovascular Research Institute, University of California San Francisco, San Francisco, California; University of California San Francisco Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029440150043
Publisher Site
http://dx.doi.org/10.1016/j.ajpath.2015.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630170PMC
November 2015

Vascular Endothelial Growth Factor C for Polycystic Kidney Diseases.

J Am Soc Nephrol 2016 Jan 2;27(1):69-77. Epub 2015 Jun 2.

Developmental Biology and Cancer Programme, UCL Institute of Child Health, London, United Kingdom;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1681/ASN.2014090856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696565PMC
January 2016

Regulation of hepatocyte growth factor in mice with pneumonia by peptidases and trans-alveolar flux.

PLoS One 2015 4;10(5):e0125797. Epub 2015 May 4.

Cardiovascular Research Institute, School of Medicine, University of California San Francisco, San Francisco, California, United States of America; Department of Medicine, School of Medicine, University of California San Francisco, San Francisco, California, United States of America; Northern California Institute for Research and Education, San Francisco, California, United States of America; Veterans Affairs Medical Center, San Francisco, California, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125797PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418689PMC
October 2015

Mast cells present protrusions into blood vessels upon tracheal allergen challenge in mice.

PLoS One 2015 19;10(3):e0118513. Epub 2015 Mar 19.

Department of Pathology, University of California San Francisco, San Francisco, California, United States of America; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, and Veterans Affairs Medical Center, San Francisco, California, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118513PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366375PMC
February 2016

Neutrophil dependence of vascular remodeling after Mycoplasma infection of mouse airways.

Am J Pathol 2014 Jun 13;184(6):1877-89. Epub 2014 Apr 13.

Cardiovascular Research Institute, Department of Anatomy, and the Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2014.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044721PMC
June 2014

Preferential lymphatic growth in bronchus-associated lymphoid tissue in sustained lung inflammation.

Am J Pathol 2014 May 11;184(5):1577-92. Epub 2014 Mar 11.

Department of Anatomy, the Cardiovascular Research Institute, and the Comprehensive Cancer Center, University of California, San Francisco, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2014.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005985PMC
May 2014

Pulmonary lymphangiectasia resulting from vascular endothelial growth factor-C overexpression during a critical period.

Circ Res 2014 Feb 15;114(5):806-22. Epub 2014 Jan 15.

From the Department of Anatomy, Cardiovascular Research Institute, Comprehensive Cancer Center, University of California, San Francisco (L.-C.Y., P.B., D.M.M.); Department of Immunology, Genetics, and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden (C.T., L.C.-W.); Wihuri Research Institute and Translational Cancer Biology Program, Biomedicum Helsinki and University of Helsinki, Helsinki, Finland (D.T., A.A., K.A.); Department of Pathology, Boston Children's Hospital, Harvard University, MA (S.O.V.), and Department of Cell Biology, ImClone Systems, Eli Lilly and Company, New York (B.P.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.114.303119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969887PMC
February 2014

Plasticity of airway lymphatics in development and disease.

Adv Anat Embryol Cell Biol 2014 ;214:41-54

Department of Anatomy, Comprehensive Cancer Center, Cardiovascular Research Institute, University of California-San Francisco, San Francisco, CA, 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-7091-1646-3_4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955364PMC
April 2014

Iron administration before stem cell harvest enables MR imaging tracking after transplantation.

Radiology 2013 Oct 12;269(1):186-97. Epub 2013 Jul 12.

Department of Radiology and Molecular Imaging Program at Stanford, Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Communication and Statistics and Department of Materials Science and Engineering, Stanford University, Stanford, Calif; Department of Neurology, Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California San Francisco, San Francisco, Calif.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1148/radiol.13130858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781357PMC
October 2013

IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia.

Int Immunol 2013 Aug 8;25(8):471-83. Epub 2013 May 8.

Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, CA 94110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/intimm/dxt012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720065PMC
August 2013

Cathepsin L protects mice from mycoplasmal infection and is essential for airway lymphangiogenesis.

Am J Respir Cell Mol Biol 2013 Sep;49(3):437-44

Department of Medicine, University of California at San Francisco, CA 94121, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2013-0016OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824055PMC
September 2013

Inhibition of c-Met reduces lymphatic metastasis in RIP-Tag2 transgenic mice.

Cancer Res 2013 Jun 10;73(12):3692-703. Epub 2013 Apr 10.

Department of Anatomy, Comprehensive Cancer Center, Cardiovascular Research Institute, University of California-San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-12-2160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686901PMC
June 2013

Transgenic overexpression of interleukin-1β induces persistent lymphangiogenesis but not angiogenesis in mouse airways.

Am J Pathol 2013 Apr 4;182(4):1434-47. Epub 2013 Feb 4.

Cardiovascular Research Institute, University of California, San Francisco, California 94143-0130, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029440130001
Publisher Site
http://dx.doi.org/10.1016/j.ajpath.2012.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620402PMC
April 2013

Controlling escape from angiogenesis inhibitors.

Nat Rev Cancer 2012 10;12(10):699-709

The UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, San Francisco, California 94143-0452, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrc3366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969886PMC
October 2012

Plasticity of button-like junctions in the endothelium of airway lymphatics in development and inflammation.

Am J Pathol 2012 Jun 23;180(6):2561-75. Epub 2012 Apr 23.

Department of Anatomy, Cardiovascular Research Institute, and the Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2012.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378913PMC
June 2012

Therapeutic angiogenesis due to balanced single-vector delivery of VEGF and PDGF-BB.

FASEB J 2012 Jun 5;26(6):2486-97. Epub 2012 Mar 5.

Baxter Laboratory for Stem Cell Biology, Institute for Regenerative Medicine and Stem Cell Biology, Department of Microbiology and Immunology, Stanford University, Stanford, California 34305-5175, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.11-197400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360154PMC
June 2012

Dynamics of airway blood vessels and lymphatics: lessons from development and inflammation.

Proc Am Thorac Soc 2011 Nov;8(6):504-7

Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1513/pats.201102-022MWDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359074PMC
November 2011

Permeability to macromolecular contrast media quantified by dynamic MRI correlates with tumor tissue assays of vascular endothelial growth factor (VEGF).

Eur J Radiol 2012 May 1;81(5):891-6. Epub 2011 Sep 1.

Center for Pharmaceutical and Molecular Imaging, Department of Radiology, University of California San Francisco, Box 0628, 505 Parnassus Ave, San Francisco, CA 94143-0628, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejrad.2011.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242157PMC
May 2012

In situ force mapping of mammary gland transformation.

Integr Biol (Camb) 2011 Sep 15;3(9):910-21. Epub 2011 Aug 15.

Department of Surgery and Center for Bioengineering and Tissue Regeneration, University of California at San Francisco, 513 Parnassus Ave, HSE 565, San Francisco, CA 94143-0456, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c1ib00043hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564969PMC
September 2011

Increased vascular delivery and efficacy of chemotherapy after inhibition of platelet-derived growth factor-B.

Am J Pathol 2011 Jun;178(6):2920-30

Cardiovascular Research Institute, Comprehensive Cancer Center, Department of Anatomy, University of California, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2011.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124291PMC
June 2011

VEGF and c-Met blockade amplify angiogenesis inhibition in pancreatic islet cancer.

Cancer Res 2011 Jul 25;71(14):4758-68. Epub 2011 May 25.

Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-10-2527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138890PMC
July 2011

Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation.

Am J Pathol 2011 Jun 6;178(6):2897-909. Epub 2011 May 6.

Department of Anatomy, Cardiovascular Research Institute, Comprehensive Cancer Center, University of California, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2011.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124300PMC
June 2011

Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors.

Cancer Res 2011 Mar;71(5):1573-83

Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California, San Francisco, California 94143-0452, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-10-3126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077087PMC
March 2011

New antibody to stop tumor angiogenesis and lymphatic spread by blocking receptor partnering.

Cancer Cell 2010 Dec;18(6):541-3

UCSF Comprehensive Cancer Center, Cardiovascular Research Institute, Department of Anatomy, University of California, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2010.11.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031147PMC
December 2010

Angiopoietin-2-driven vascular remodeling in airway inflammation.

Am J Pathol 2010 Dec 15;177(6):3233-43. Epub 2010 Oct 15.

Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California, San Francisco, California 94143-0425, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2353/ajpath.2010.100059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993300PMC
December 2010

Rapid remodeling of airway vascular architecture at birth.

Dev Dyn 2010 Sep;239(9):2354-66

Cardiovascular Research Institute, Comprehensive Cancer Center, Department of Anatomy, University of California, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/dvdy.22379
Publisher Site
http://dx.doi.org/10.1002/dvdy.22379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997630PMC
September 2010

Lymphotoxin-alpha contributes to lymphangiogenesis.

Blood 2010 Sep 21;116(12):2173-82. Epub 2010 Jun 21.

Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2009-12-256065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951858PMC
September 2010

Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth.

Cancer Res 2010 Mar 2;70(6):2213-23. Epub 2010 Mar 2.

Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California, San Francisco, California 94143-0452, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-09-1977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840050PMC
March 2010

Ricinus communis agglutinin I leads to rapid down-regulation of VEGFR-2 and endothelial cell apoptosis in tumor blood vessels.

Am J Pathol 2010 Apr 25;176(4):1927-40. Epub 2010 Feb 25.

Department of Anatomy, University of California, San Francisco, CA 94143-0452, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2353/ajpath.2010.090561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843481PMC
April 2010

Steroid-resistant lymphatic remodeling in chronically inflamed mouse airways.

Am J Pathol 2010 Mar 21;176(3):1525-41. Epub 2010 Jan 21.

Department of Anatomy, University of California, 513 Parnassus Ave., Room S1363, San Francisco, CA 94143-0452, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2353/ajpath.2010.090909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832171PMC
March 2010

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning.

J Exp Med 2010 Jan 21;207(1):17-27. Epub 2009 Dec 21.

Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20091619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812554PMC
January 2010

TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice.

J Clin Invest 2009 Oct 14;119(10):2954-64. Epub 2009 Sep 14.

Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California-San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI37626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752063PMC
October 2009

Correlative dynamic contrast MRI and microscopic assessments of tumor vascularity in RIP-Tag2 transgenic mice.

Magn Reson Med 2009 Sep;62(3):616-25

Department of Cardiovascular Research Institute, Comprehensive Cancer Center, University of California, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/mrm.22040
Publisher Site
http://dx.doi.org/10.1002/mrm.22040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675714PMC
September 2009

alpha5beta1 Integrin blockade inhibits lymphangiogenesis in airway inflammation.

Am J Pathol 2009 Jun 14;174(6):2378-87. Epub 2009 May 14.

Department of Anatomy, S1363, University of California, 513 Parnassus Avenue, San Francisco, CA 94143-0452, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2353/ajpath.2009.080942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684201PMC
June 2009

Capillary defects and exaggerated inflammatory response in the airways of EphA2-deficient mice.

Am J Pathol 2009 Jun 14;174(6):2388-99. Epub 2009 May 14.

Department of Anatomy, S1363, University of California, 513 Parnassus Avenue, San Francisco, CA 94143-0452, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029440106109
Publisher Site
http://dx.doi.org/10.2353/ajpath.2009.080949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684202PMC
June 2009

Cellular source and amount of vascular endothelial growth factor and platelet-derived growth factor in tumors determine response to angiogenesis inhibitors.

Cancer Res 2009 May 28;69(10):4527-36. Epub 2009 Apr 28.

Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California, San Francisco, CA 94143-0452, USA.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-08-3779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759816PMC
May 2009

Relaxation effects of ferucarbotran-labeled mesenchymal stem cells at 1.5T and 3T: discrimination of viable from lysed cells.

Magn Reson Med 2009 Aug;62(2):325-32

Department of Radiology, University of California, San Francisco (UCSF) Medical Center, UCSF, San Francisco, CA 94143-0628, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrm.22011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931823PMC
August 2009

The hepatocyte growth factor/c-Met signaling pathway as a therapeutic target to inhibit angiogenesis.

BMB Rep 2008 Dec;41(12):833-9

Department of Anatomy, University of California, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417610PMC
http://dx.doi.org/10.5483/bmbrep.2008.41.12.833DOI Listing
December 2008

Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity.

Genes Dev 2008 Dec;22(23):3282-91

Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.1727208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600759PMC
December 2008

Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees.

Cell Tissue Res 2009 Jan 15;335(1):17-25. Epub 2008 Oct 15.

IFOM , FIRC Institute of Molecular Oncology, Via Adamello 16, 20139 Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00441-008-0694-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422058PMC
January 2009

Magnetic resonance imaging for monitoring the effects of thalidomide on experimental human breast cancers.

Eur Radiol 2009 Jan 30;19(1):121-31. Epub 2008 Jul 30.

Center for Pharmaceutical and Molecular Imaging, Department of Radiology, University of California San Francisco, San Francisco, CA 94143-0628, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00330-008-1111-x
Publisher Site
http://dx.doi.org/10.1007/s00330-008-1111-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685658PMC
January 2009

Markers for microscopic imaging of lymphangiogenesis and angiogenesis.

Ann N Y Acad Sci 2008 ;1131:1-12

Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California, San Francisco, California 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1196/annals.1413.001DOI Listing
July 2008

Magnetic resonance imaging assays for dimethyl sulfoxide effect on cancer vasculature.

Invest Radiol 2008 May;43(5):298-305

Center for Pharmaceutical and Molecular Imaging, Department of Radiology, University of California San Francisco, San Francisco, CA 94143-0628, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RLI.0b013e318164b71dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423758PMC
May 2008

Vascular permeability during antiangiogenesis treatment: MR imaging assay results as biomarker for subsequent tumor growth in rats.

Radiology 2008 May 27;247(2):391-9. Epub 2008 Mar 27.

Department of Radiology, Center for Pharmaceutical and Molecular Imaging, Cardiovascular Research Institute, Comprehensive Cancer Center, University of California San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1148/radiol.2472070363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423757PMC
May 2008

Disease-specific gene expression profiling in multiple models of lung disease.

Am J Respir Crit Care Med 2008 Feb 20;177(4):376-87. Epub 2007 Nov 20.

Cincinnati Children's Hospital Medical Center/Division of Immunobiology, 3333 Burnet Avenue, MLC 7038, Cincinnati, OH 45229, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.200702-333OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258439PMC
February 2008

Functionally specialized junctions between endothelial cells of lymphatic vessels.

J Exp Med 2007 Oct 10;204(10):2349-62. Epub 2007 Sep 10.

Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20062596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118470PMC
October 2007

The biologic basis of in vivo angiogenesis imaging.

Front Biosci 2007 May 1;12:3601-16. Epub 2007 May 1.

Molecular Imaging Program, National Institutes of Health, Bethesda, Maryland 20892-1182, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2741/2337DOI Listing
May 2007

Cell labeling with the positive MR contrast agent Gadofluorine M.

Eur Radiol 2007 May 6;17(5):1226-34. Epub 2007 Jan 6.

Department of Radiology, University of California in San Francisco, 505 Parnassus Ave, San Francisco, CA, 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00330-006-0522-9DOI Listing
May 2007

In vivo actions of angiopoietins on quiescent and remodeling blood and lymphatic vessels in mouse airways and skin.

Arterioscler Thromb Vasc Biol 2007 Mar 28;27(3):564-70. Epub 2006 Dec 28.

National Research Laboratory of Vascular Biology and Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.ATV.0000256458.82320.beDOI Listing
March 2007

Rapid vascular regrowth in tumors after reversal of VEGF inhibition.

J Clin Invest 2006 Oct;116(10):2610-21

Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, UCSF, San Francisco, California 94143-0452, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI24612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1578604PMC
October 2006

Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung.

Proc Natl Acad Sci U S A 2006 Jul 10;103(29):11021-6. Epub 2006 Jul 10.

Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, LCI 401-B, New Haven, CT 06520-8057, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0601057103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1544167PMC
July 2006

Antiangiogenic therapy decreases integrin expression in normalized tumor blood vessels.

Cancer Res 2006 Mar;66(5):2639-49

Department of Anatomy, University of California, San Francisco, California 91413-0452, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-05-1824DOI Listing
March 2006

Effect of inhibition of vascular endothelial growth factor signaling on distribution of extravasated antibodies in tumors.

Cancer Res 2006 Feb;66(3):1434-45

Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California-San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143-0130, USA.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-05-0923DOI Listing
February 2006

Imaging of angiogenesis in inflamed airways and tumors: newly formed blood vessels are not alike and may be wildly abnormal: Parker B. Francis lecture.

Chest 2005 Dec;128(6 Suppl):602S-608S

Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California, San Francisco, CA 94143-0452, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1378/chest.128.6_suppl.602S-aDOI Listing
December 2005

Immune complex-dependent remodeling of the airway vasculature in response to a chronic bacterial infection.

J Immunol 2005 Nov;175(10):6319-26

Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.175.10.6319DOI Listing
November 2005

Mast cells protect mice from Mycoplasma pneumonia.

Am J Respir Crit Care Med 2006 Jan 6;173(2):219-25. Epub 2005 Oct 6.

Pulmonary and Critical Care Medicine, Mailstop 111-D, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121.

View Article

Download full-text PDF

Source
http://www.atsjournals.org/doi/abs/10.1164/rccm.200507-1034O
Publisher Site
http://dx.doi.org/10.1164/rccm.200507-1034OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662990PMC
January 2006

Angiogenesis with pericyte abnormalities in a transgenic model of prostate carcinoma.

Cancer 2005 Nov;104(10):2104-15

Department of Anatomy, University of California at San Francisco, San Francisco, California 94143-0130, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.21436DOI Listing
November 2005

Cellular changes in normal blood capillaries undergoing regression after inhibition of VEGF signaling.

Am J Physiol Heart Circ Physiol 2006 Feb 19;290(2):H547-59. Epub 2005 Sep 19.

Cardiovascular Research Institute, and Dept. of Anatomy, Univ. of California, 513 Parnassus Ave., San Francisco, CA 94143-0452, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpheart.00616.2005DOI Listing
February 2006

Angiopoietin-1 decreases plasma leakage by reducing number and size of endothelial gaps in venules.

Am J Physiol Heart Circ Physiol 2006 Jan 26;290(1):H107-18. Epub 2005 Aug 26.

Cardiovascular Research Institute, and Dept. of Anatomy, Univ. of California, San Francisco, CA 94143-0452, USA.

View Article

Download full-text PDF

Source
http://www.physiology.org/doi/10.1152/ajpheart.00542.2005
Publisher Site
http://dx.doi.org/10.1152/ajpheart.00542.2005DOI Listing
January 2006

Mosaic tumor vessels: cellular basis and ultrastructure of focal regions lacking endothelial cell markers.

Cancer Res 2005 Jul;65(13):5740-9

Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-04-4552DOI Listing
July 2005

Uniform overexpression and rapid accessibility of alpha5beta1 integrin on blood vessels in tumors.

Am J Pathol 2005 Jul;167(1):193-211

Department of Anatomy, Cardiovascular Research Institute, Comprehensive Cancer Center, University of California, 513 Parnassus Ave., San Francisco, CA 94143-0452, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1603436PMC
http://dx.doi.org/10.1016/s0002-9440(10)62965-3DOI Listing
July 2005

Long-term and sustained COMP-Ang1 induces long-lasting vascular enlargement and enhanced blood flow.

Circ Res 2005 Jul 16;97(1):86-94. Epub 2005 Jun 16.

Biomedical Research Center and Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.RES.0000174093.64855.a6DOI Listing
July 2005

Angiopoietin 1 causes vessel enlargement, without angiogenic sprouting, during a critical developmental period.

Development 2005 Jul 15;132(14):3317-26. Epub 2005 Jun 15.

Regeneron Pharmaceuticals Incorporated, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.01888DOI Listing
July 2005

Rapid access of antibodies to alpha5beta1 integrin overexpressed on the luminal surface of tumor blood vessels.

Cancer Res 2005 Apr;65(7):2712-21

Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California, San Francisco, California 94143-0130, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-04-2691DOI Listing
April 2005

Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection.

Am J Pathol 2005 Feb;166(2):625-36

Departments of Genitourinary Medical Oncology and Cancer Biology, The University of Texas, M.D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1602338PMC
http://dx.doi.org/10.1016/S0002-9440(10)62283-3DOI Listing
February 2005

Cellular abnormalities of blood vessels as targets in cancer.

Curr Opin Genet Dev 2005 Feb;15(1):102-11

Cardiovascular Research Institute, Comprehensive Cancer Center, Department of Anatomy, University of California, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gde.2004.12.005DOI Listing
February 2005

Shear stress-induced upregulation of connexin 43 expression in endothelial cells on upstream surfaces of rat cardiac valves.

Histochem Cell Biol 2004 Nov 3;122(5):477-83. Epub 2004 Nov 3.

Department of Developmental Molecular Anatomy, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, 812-8582 Fukuoka, Japan.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00418-004-0717-6
Publisher Site
http://dx.doi.org/10.1007/s00418-004-0717-6DOI Listing
November 2004

Regulated angiogenesis and vascular regression in mice overexpressing vascular endothelial growth factor in airways.

Am J Pathol 2004 Oct;165(4):1071-85

Cardiovascular Research Institute, Comprehensive Cancer Center, Department of Anatomy, University of California, San Francisco, CA 94143-0130, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618646PMC
http://dx.doi.org/10.1016/S0002-9440(10)63369-XDOI Listing
October 2004

Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung.

Nat Med 2004 Oct 19;10(10):1095-103. Epub 2004 Sep 19.

Section of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street, 441c TAC, New Haven, Connecticut 06520-8057, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm1105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434232PMC
October 2004

Matrix metalloproteinase-2 and -9 expression increases in Mycoplasma-infected airways but is not required for microvascular remodeling.

Am J Physiol Lung Cell Mol Physiol 2004 Aug 9;287(2):L307-17. Epub 2004 Apr 9.

Cardiovascular Research Institute, University of California, San Francisco, CA 94143-0130, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajplung.00404.2003DOI Listing
August 2004

Age-related changes in vascular endothelial growth factor dependency and angiopoietin-1-induced plasticity of adult blood vessels.

Circ Res 2004 Apr 4;94(7):984-92. Epub 2004 Mar 4.

Department of Anatomy, Cardiovascular Research Institute and Comprehensive Cancer Center, University of California, San Francisco, Calif, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.RES.0000125295.43813.1FDOI Listing
April 2004

Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis.

J Clin Invest 2004 Feb;113(4):516-27

Baxter Laboratory in Genetic Pharmacology, Stanford University School of Medicine, Stanford, California 94305-5175, USA.

View Article

Download full-text PDF

Source
http://www.jci.org/articles/view/18420
Publisher Site
http://dx.doi.org/10.1172/JCI18420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC338257PMC
February 2004

Mechanisms of increased immunogenicity for DNA-based vaccines adsorbed onto cationic microparticles.

Cell Immunol 2003 Sep;225(1):12-20

Department of Anatomy and Cardiovascular Research Institute, University of California at San Francisco, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cellimm.2003.09.003DOI Listing
September 2003

Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors.

Am J Pathol 2003 Nov;163(5):1801-15

Cardiovascular Research Institute, Comprehensive Cancer Center, University of California-San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143-0452, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892429PMC
http://dx.doi.org/10.1016/S0002-9440(10)63540-7DOI Listing
November 2003