Publications by authors named "Donald G Robertson"

23Publications

Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease.

Amino Acids 2015 Mar 23;47(3):603-15. Epub 2014 Dec 23.

Department of Pharmacology and Toxicology, The University of Arizona, 1703 East Mabel St, PO Box 210207, Tucson, AZ, 85721, USA.

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http://dx.doi.org/10.1007/s00726-014-1894-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329055PMC
March 2015

Pharmacometabonomic investigation of dynamic metabolic phenotypes associated with variability in response to galactosamine hepatotoxicity.

J Proteome Res 2012 Apr 2;11(4):2427-40. Epub 2012 Mar 2.

Biomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, United Kingdom.

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http://pubs.acs.org/doi/10.1021/pr201161f
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http://dx.doi.org/10.1021/pr201161fDOI Listing
April 2012

Metabolomic and transcriptomic changes induced by overnight (16 h) fasting in male and female Sprague-Dawley rats.

Chem Res Toxicol 2011 Apr 25;24(4):481-7. Epub 2011 Mar 25.

Applied and Investigative Metabolomics, Bristol-Myers Squibb Co., Princeton, NJ 08543, USA.

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http://dx.doi.org/10.1021/tx200074fDOI Listing
April 2011

Metabolomics in toxicology: preclinical and clinical applications.

Toxicol Sci 2011 Mar 2;120 Suppl 1:S146-70. Epub 2010 Dec 2.

Applied and Investigative Metabolomics, Bristol-Myers Squibb Co., Princeton, New Jersey 08543, USA.

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http://dx.doi.org/10.1093/toxsci/kfq358DOI Listing
March 2011

Muscling mussels: metabolomic evaluation of toxicity.

Toxicol Sci 2010 Jun;115(2):305-6

Applied and Investigative Metabonomics, Bristol-Myers Squibb Company, Princeton, New Jersey 08543, USA.

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http://dx.doi.org/10.1093/toxsci/kfq088DOI Listing
June 2010

Chemical shift calibration of 1H MAS NMR liver tissue spectra exemplified using a study of glycine protection of galactosamine toxicity.

Magn Reson Chem 2009 Dec;47 Suppl 1:S47-53

Biomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, South Kensington, London SW7 2AZ, UK.

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http://dx.doi.org/10.1002/mrc.2521DOI Listing
December 2009

The muddle of models: what you don't know can hurt you.

Chem Res Toxicol 2008 Oct 26;21(10):1917-22. Epub 2008 Aug 26.

Applied and Investigative Metabonomics, Bristol-Myers Squibb Company, Princeton, New Jersey 08543, USA.

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http://dx.doi.org/10.1021/tx800204gDOI Listing
October 2008

Metabonomic evaluation of metabolic dysregulation in rats induced by PF 376304, a novel inhibitor of phosphoinositide 3-kinase.

Chem Res Toxicol 2007 Dec 15;20(12):1871-7. Epub 2007 Nov 15.

Metabonomics Evaluation Group and Drug Safety Research and Development, Pfizer Global Research and Development, Ann Arbor, MI 48105, USA.

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http://dx.doi.org/10.1021/tx7002036DOI Listing
December 2007

Heteronuclear 1H-31P statistical total correlation NMR spectroscopy of intact liver for metabolic biomarker assignment: application to galactosamine-induced hepatotoxicity.

Anal Chem 2007 Dec 1;79(23):8956-66. Epub 2007 Nov 1.

Department of Biomolecular Medicine, Sir Alexander Fleming Building, SORA Division, Faculty of Medicine, Imperial College London, SW7 2AZ, U.K.

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http://dx.doi.org/10.1021/ac0713961DOI Listing
December 2007

Metabonomic evaluation of Schaedler altered microflora rats.

Chem Res Toxicol 2007 Oct 28;20(10):1388-92. Epub 2007 Sep 28.

Metabonomics Evaluation Group, Pfizer Global Research and Development, An Arbor, MI 48105, USA.

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http://dx.doi.org/10.1021/tx700184uDOI Listing
October 2007

Metabonomics in pharmaceutical discovery and development.

J Proteome Res 2007 Feb;6(2):526-39

Metabonomics Evaluation Group, Pfizer Global Research and Development, 2800 Plymouth Road, Ann Arbor, MI 48105, USA.

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http://dx.doi.org/10.1021/pr060535cDOI Listing
February 2007

Metabonomics in preclinical drug development.

Expert Opin Drug Metab Toxicol 2005 Oct;1(3):363-76

Pfizer Global Research and Development, Department of World Wide Safety Sciences, 2800 Plymouth Rd, Ann Arbor, MI 48105, USA.

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http://dx.doi.org/10.1517/17425255.1.3.363DOI Listing
October 2005

Mechanisms and biomarkers of cardiovascular injury induced by phosphodiesterase inhibitor III SK&F 95654 in the spontaneously hypertensive rat.

Toxicol Pathol 2006 ;34(2):152-63

Division of Applied Pharmacology Research (HFD-910), Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, USA.

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http://dx.doi.org/10.1080/01926230600588562DOI Listing
August 2006

Communication regarding metabonomic identification of two distinct phenotypes in Sprague-Dawley (Crl:CD(SD)) rats.

Toxicol Sci 2006 May 16;91(1):309. Epub 2006 Feb 16.

Pfizer Global Research and Development, Metabonomics Evaluation Group, Ann Arbor, Michigan 48105, USA.

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http://dx.doi.org/10.1093/toxsci/kfj134DOI Listing
May 2006

Metabonomic identification of two distinct phenotypes in Sprague-Dawley (Crl:CD(SD)) rats.

Toxicol Sci 2005 Sep 2;87(1):277-84. Epub 2005 Jun 2.

Pfizer Global Research and Development, Metabonomics Evaluation Group, Ann Arbor, Michigan 48105, USA.

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http://dx.doi.org/10.1093/toxsci/kfi214DOI Listing
September 2005

Metabonomics in toxicology: a review.

Toxicol Sci 2005 Jun 2;85(2):809-22. Epub 2005 Feb 2.

Metabonomics Evaluation Group, Department of World-Wide Safety Sciences, Pfizer Global Research and Development, Ann Arbor, Michigan 48105, USA.

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http://dx.doi.org/10.1093/toxsci/kfi102DOI Listing
June 2005

In vivo toxicity screening programs using metabonomics.

Comb Chem High Throughput Screen 2002 Dec;5(8):651-62

Department of Discovery Technologies, Pfizer Global Research and Development, Ann Arbor, MI 48105, USA.

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http://dx.doi.org/10.2174/1386207023329932DOI Listing
December 2002

Effect of dexamethasone on the metabonomics profile associated with phosphodiesterase inhibitor-induced vascular lesions in rats.

Toxicol Appl Pharmacol 2002 Sep;183(2):108-9

Department of Drug Safety Evaluation, Prizer Global Research and Development, Ann Arbor, MI 48106-1047, USA.

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September 2002