Donald F Conrad

Donald F Conrad

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Donald F Conrad

Publications by authors named "Donald F Conrad"

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Identification of genetic variants in CFAP221 as a cause of primary ciliary dyskinesia.

J Hum Genet 2019 Oct 21. Epub 2019 Oct 21.

Department of Pathology and Laboratory Medicine, Marsico Lung Institute University of North Carolina, Chapel Hill, NC, 27599, USA.

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http://dx.doi.org/10.1038/s10038-019-0686-1DOI Listing
October 2019

Unified single-cell analysis of testis gene regulation and pathology in five mouse strains.

Elife 2019 06 25;8. Epub 2019 Jun 25.

Department of Genetics, Washington University School of Medicine, St. Louis, United States.

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http://dx.doi.org/10.7554/eLife.43966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615865PMC
June 2019

Genetic intersection of male infertility and cancer.

Fertil Steril 2018 01;109(1):20-26

Department of Genetics, Washington University School of Medicine, St. Louis, Missouri. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2017.10.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761685PMC
January 2018

The long and short of translational control in male germ cells.

Biol Reprod 2017 07;97(1):2-4

Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1093/biolre/iox075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248522PMC
July 2017

The impact of structural variation on human gene expression.

Nat Genet 2017 May 3;49(5):692-699. Epub 2017 Apr 3.

McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1038/ng.3834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406250PMC
May 2017

How to Map the Genetic Basis for Conditions that are Comorbid with Male Infertility.

Semin Reprod Med 2017 05 28;35(3):225-230. Epub 2017 Jun 28.

Department of Genetics, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1055/s-0037-1603567DOI Listing
May 2017

Multiplex shRNA Screening of Germ Cell Development by in Vivo Transfection of Mouse Testis.

G3 (Bethesda) 2017 01 5;7(1):247-255. Epub 2017 Jan 5.

Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110

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http://dx.doi.org/10.1534/g3.116.036087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217113PMC
January 2017

Genome-wide significance testing of variation from single case exomes.

Nat Genet 2016 12 24;48(12):1455-1461. Epub 2016 Oct 24.

Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1038/ng.3697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127779PMC
December 2016

Defining the Phenotype and Assessing Severity in Phosphoglucomutase-1 Deficiency.

J Pediatr 2016 08 17;175:130-136.e8. Epub 2016 May 17.

Hayward Genetics Center, Tulane University School of Medicine, New Orleans, LA; Department of Pediatrics, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.jpeds.2016.04.021DOI Listing
August 2016

A Screen for Genomic Disorders of Infertility Identifies MAST2 Duplications Associated with Nonobstructive Azoospermia in Humans.

Biol Reprod 2015 Sep 22;93(3):61. Epub 2015 Jul 22.

State Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing, China Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China

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http://dx.doi.org/10.1095/biolreprod.115.131185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710186PMC
September 2015

Using whole-genome sequences of the LG/J and SM/J inbred mouse strains to prioritize quantitative trait genes and nucleotides.

BMC Genomics 2015 May 28;16:415. Epub 2015 May 28.

Department of Genetics, Washington University School of Medicine, Campus Box 8108, 660 S Euclid Ave, St Louis, MO, 63110, USA.

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http://dx.doi.org/10.1186/s12864-015-1592-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445795PMC
May 2015

Validating single-cell genomics for the study of renal development.

Kidney Int 2014 Nov 23;86(5):1049-55. Epub 2014 Apr 23.

1] Department of Genetics, Washington University, School of Medicine, St Louis, Missouri, USA [2] Center for Genome Sciences and Systems Biology, Washington University School of Medicine, Washington University School of Medicine, St Louis, Missouri, USA.

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http://dx.doi.org/10.1038/ki.2014.104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207726PMC
November 2014

Cis and trans effects of human genomic variants on gene expression.

PLoS Genet 2014 Jul 10;10(7):e1004461. Epub 2014 Jul 10.

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland; Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland; Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland; Center of Excellence for Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia.

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http://dx.doi.org/10.1371/journal.pgen.1004461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091791PMC
July 2014

Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing.

PLoS Genet 2014 Jul 10;10(7):e1004462. Epub 2014 Jul 10.

Department of Internal Medicine, Division of Oncology, Washington University, St. Louis, Missouri, United States of America; Siteman Cancer Center, Washington University, St. Louis, Missouri, United States of America; Department of Pathology and Immunology, Washington University, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091781PMC
July 2014

Reduced burden of very large and rare CNVs in bipolar affective disorder.

Bipolar Disord 2013 Dec 16;15(8):893-8. Epub 2013 Oct 16.

MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff.

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http://dx.doi.org/10.1111/bdi.12125DOI Listing
December 2013

DeNovoGear: de novo indel and point mutation discovery and phasing.

Nat Methods 2013 Oct 25;10(10):985-7. Epub 2013 Aug 25.

1] Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA. [2].

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http://www.nature.com/articles/nmeth.2611
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http://dx.doi.org/10.1038/nmeth.2611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003501PMC
October 2013

A review of genome-wide approaches to study the genetic basis for spermatogenic defects.

Methods Mol Biol 2013 ;927:397-410

Department of Surgery, Division of Urology, Andrology & IVF Laboratories, University of Utah School of Medicine, Salt Lake City, UT, USA,

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http://dx.doi.org/10.1007/978-1-62703-038-0_34DOI Listing
January 2013

Independent estimation of the frequency of rare CNVs in the UK population confirms their role in schizophrenia.

Schizophr Res 2012 Mar 29;135(1-3):1-7. Epub 2011 Nov 29.

MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK.

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http://dx.doi.org/10.1016/j.schres.2011.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315675PMC
March 2012

Meeting on big mutations addresses big questions in human genetics.

Authors:
Donald F Conrad

Genome Med 2011 Feb 22;3(2):12. Epub 2011 Feb 22.

Department of Genetics, Washington University School of Medicine, St Louis, MO, USA.

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http://genomemedicine.biomedcentral.com/articles/10.1186/gm2
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http://dx.doi.org/10.1186/gm226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092097PMC
February 2011

Towards a comprehensive structural variation map of an individual human genome.

Genome Biol 2010 19;11(5):R52. Epub 2010 May 19.

Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.

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http://dx.doi.org/10.1186/gb-2010-11-5-r52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898065PMC
September 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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http://dx.doi.org/10.1038/nature08979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892339PMC
April 2010

A protein allergen microarray detects specific IgE to pollen surface, cytoplasmic, and commercial allergen extracts.

PLoS One 2010 Apr 16;5(4):e10174. Epub 2010 Apr 16.

Department of Human Genetics, The University of Chicago, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010174PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856625PMC
April 2010

Inverted duplications on acentric markers: mechanism of formation.

Hum Mol Genet 2009 Jun 31;18(12):2241-56. Epub 2009 Mar 31.

Department of Human Genetics, The University of Chicago, 5841 S. Maryland Avenue, Room L-155, MC0077, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/hmg/ddp160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685760PMC
June 2009

Recurrent 16p11.2 microdeletions in autism.

Hum Mol Genet 2008 Feb 21;17(4):628-38. Epub 2007 Dec 21.

Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/hmg/ddm376DOI Listing
February 2008

The population genetics of structural variation.

Nat Genet 2007 Jul;39(7 Suppl):S30-6

Department of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA.

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http://www.nature.com/doifinder/10.1038/ng2042
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http://dx.doi.org/10.1038/ng2042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716079PMC
July 2007

A worldwide survey of haplotype variation and linkage disequilibrium in the human genome.

Nat Genet 2006 Nov 22;38(11):1251-60. Epub 2006 Oct 22.

Department of Human Genetics, University of Chicago, 920 East 58th Street, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1038/ng1911DOI Listing
November 2006

Mismatch induced speciation in Salmonella: model and data.

Philos Trans R Soc Lond B Biol Sci 2006 Nov;361(1475):2045-53

Peter Medawar Building for Pathogen Research, Oxford University, Oxford OX1 3SY, UK.

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http://dx.doi.org/10.1098/rstb.2006.1925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764929PMC
November 2006

A high-resolution survey of deletion polymorphism in the human genome.

Nat Genet 2006 Jan 4;38(1):75-81. Epub 2005 Dec 4.

Department of Human Genetics, The University of Chicago, 920 East 58th Street, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1038/ng1697DOI Listing
January 2006