Dominique Wendum

Dominique Wendum

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Dominique Wendum

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Hepatocellular Carcinomas With Mutational Activation of Beta-Catenin Require Choline and Can Be Detected by Positron Emission Tomography.

Gastroenterology 2019 09 10;157(3):807-822. Epub 2019 Jun 10.

Institut Cochin, Institut National de la Santé et de la Recherche Médicale U1016, Centre National de la Recherche Scientifique, Unité Mixte De Recherché 8104, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Centre de Recherche des Cordeliers, Institut National de la Santé et de la Recherche Médicale Unité Mixte De Recherche 1138, Equipe Labellisée Ligue Contre le Cancer, Paris, France. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.05.069DOI Listing
September 2019

Preclinical Evaluation of Ga-DOTA-NT-20.3: A Promising PET Imaging Probe To Discriminate Human Pancreatic Ductal Adenocarcinoma from Pancreatitis.

Mol Pharm 2019 06 3;16(6):2776-2784. Epub 2019 May 3.

Sorbonne Université, UMS28 Phénotypage du Petit Animal, Laboratoire d'Imagerie Moléculaire Positonique (LIMP) , Paris 75020 , France.

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http://dx.doi.org/10.1021/acs.molpharmaceut.9b00283DOI Listing
June 2019

Non-contrast MR lymphography of the lymphatic system of the liver.

Eur Radiol 2019 Apr 1. Epub 2019 Apr 1.

Faculté de Médecine Pierre et Marie Curie and Department of Radiology, Saint-Antoine Hospital, Assistance Publique-Hôpitaux de Paris, Sorbonne Université, 184 Rue du Faubourg Saint-Antoine, 75012, Paris, France.

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http://dx.doi.org/10.1007/s00330-019-06151-6DOI Listing
April 2019

Diet-Induced Dysbiosis and Genetic Background Synergize With Cystic Fibrosis Transmembrane Conductance Regulator Deficiency to Promote Cholangiopathy in Mice.

Hepatol Commun 2018 Dec 10;2(12):1533-1549. Epub 2018 Oct 10.

Sorbonne Université, INSERM Centre de Recherche Saint-Antoine (CRSA), and Institute of Cardiometabolism and Nutrition (ICAN) Paris France.

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http://dx.doi.org/10.1002/hep4.1266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287479PMC
December 2018

Low Levels of Microsatellite Instability at Simple Repeated Sequences Commonly Occur in Human Hepatocellular Carcinoma.

Cancer Genomics Proteomics 2017 Sep-Oct;14(5):329-339

Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Centre de Recherche Saint-Antoine (CRSA), Paris, France

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http://dx.doi.org/10.21873/cgp.20043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611519PMC
May 2018

Chronic Hepatitis E Viral Infection After Liver Transplantation: A Regression of Fibrosis After Antiviral Therapy.

Transplantation 2017 09;101(9):2083-2087

1 APHP, Hôpital Pitié-Salpêtrière, Unité Médicale de Transplantation Hépatique, Hépato-Gastro-Enterologie. Hôpital Pitié-Salpêtrière UPMC Paris VI, Boulevard de l'Hôpital, Paris, France. 2 Medicina Traslazionale, Università Piemonte Orientale Amedeo Avogrado, Italy. 3 APHP, Hôpital Pitié-Salpêtrière, Service d'Anatomie et Cytologie Pathologique, Paris, France. 4 APHP, Hôpital Pitié-Salpêtrière, Service d'Anesthésie-Réanimation, Paris, France. 5 APHP, Hôpital Saint Antoine, Service d'Anatomie et Cytologie Pathologique, Paris, France.

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http://dx.doi.org/10.1097/TP.0000000000001766DOI Listing
September 2017

Neurotensin regulation induces overexpression and activation of EGFR in HCC and restores response to erlotinib and sorafenib.

Cancer Lett 2017 03 1;388:73-84. Epub 2016 Dec 1.

INSERM UMRS 1007, Université Paris Descartes, 75270 Paris Cedex 06, France. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.11.032DOI Listing
March 2017

Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation.

Gastroenterology 2017 03 7;152(4):880-894.e6. Epub 2016 Dec 7.

Unité Mixte de Recherche 1162, Génomique Fonctionnelle des Tumeurs Solides, Institut National de la Santé et de la Recherche Médicale, Université Paris Descartes, Université Paris Diderot, Paris, France; Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Département d'Oncologie, Paris, France. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.11.042DOI Listing
March 2017

Somatostatin receptors in resected hepatocellular carcinoma: status and correlation with markers of poor prognosis.

Histopathology 2017 Feb 10;70(3):492-498. Epub 2016 Nov 10.

Saint-Antoine Research Centre, Sorbonne Universités, UPMC Univ. Paris 06, UMR_S 938, Paris, France.

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http://dx.doi.org/10.1111/his.13034DOI Listing
February 2017

Hepatocellular adenoma with malignant transformation in a patient with neonatal portal vein thrombosis.

Hepatology 2016 08 27;64(2):675-7. Epub 2016 May 27.

Sorbonne Universités, UPMC, Paris VI, Paris, France.

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http://dx.doi.org/10.1002/hep.28590DOI Listing
August 2016

Hepatic epithelioid hemangioendothelioma.

Clin Res Hepatol Gastroenterol 2016 Apr 3;40(2):136-8. Epub 2015 Nov 3.

Sorbonne universités, UPMC - université Paris 06, faculté de médecine Pierre-et-Marie-Curie and Department of Radiology and Pathology, Saint-Antoine Hospital, Assistance publique-Hôpitaux de Paris, 184, rue de Faubourg-Saint-Antoine, 75012 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2015.10.002DOI Listing
April 2016

Diagnosing Nodular Regenerative Hyperplasia of the Liver Is Thwarted by Low Interobserver Agreement.

PLoS One 2015 8;10(6):e0120299. Epub 2015 Jun 8.

Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, the Netherlands; Department of Internal Medicine, Gastroenterology and Geriatrics, ORBIS Medical Center, Sittard-Geleen, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120299PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459699PMC
February 2016

Mitogen-activated protein kinase-activated protein kinase 2 mediates resistance to hydrogen peroxide-induced oxidative stress in human hepatobiliary cancer cells.

Free Radic Biol Med 2015 Dec 11;89:34-46. Epub 2015 Jul 11.

INSERM UPMC Univ Paris 06, UMR_S 938, Centre de Recherche Saint-Antoine, F-75012 Paris, France; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 938, Centre de Recherche Saint-Antoine, F-75012 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2015.07.011DOI Listing
December 2015

Hepatic nodular lymphoid lesion with increased IgG4-positive plasma cells associated with primary biliary cirrhosis: a report of two cases.

Virchows Arch 2015 Nov 10;467(5):613-7. Epub 2015 Sep 10.

Department of Pathology, AP-HP Hôpital Saint-Antoine, 184 rue du Faubourg Saint-Antoine, F-75012, Paris, France.

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http://dx.doi.org/10.1007/s00428-015-1841-5DOI Listing
November 2015

[Cholangitis with granulocytic epithelial lesion: a new entity with a specific treatment].

Ann Pathol 2015 Aug 15;35(4):364-7. Epub 2015 Jul 15.

Service d'anatomie et cytologie pathologiques, hôpital Saint-Antoine, AP-HP, 184, rue du Faubourg-Saint-Antoine, 75571 Paris cedex 12, France; UPMC, université Paris 06, 75005 Paris, France.

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http://dx.doi.org/10.1016/j.annpat.2015.05.002DOI Listing
August 2015

Portal myofibroblasts promote vascular remodeling underlying cirrhosis formation through the release of microparticles.

Hepatology 2015 Mar 22;61(3):1041-55. Epub 2015 Jan 22.

Sorbonne Universités, UPMC Université Paris 06, CDR Saint-Antoine and Institute of Cardiometabolism and Nutrition (ICAN), Paris, France; INSERM, UMR_S 938, Paris, France.

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http://doi.wiley.com/10.1002/hep.27318
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http://dx.doi.org/10.1002/hep.27318DOI Listing
March 2015

Feasibility and survival of 2-stage hepatectomy for colorectal metastases: definition of a simple and early clinicopathologic predicting score.

Surgery 2015 Mar 6;157(3):444-53. Epub 2014 Nov 6.

Departments of Hepatobiliary Surgery and Liver Transplantation, Hôpital Saint Antoine, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.surg.2014.09.033DOI Listing
March 2015

Primary biliary cirrhosis: proposal for a new simple histological scoring system.

Liver Int 2015 Feb 8;35(2):652-9. Epub 2014 Jul 8.

Anatomie Pathologique, AP-HP, Hôpital St Antoine, Paris, France; Sorbonne Universités, UPMC Université Paris 06, Paris, France.

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http://dx.doi.org/10.1111/liv.12620DOI Listing
February 2015

EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition.

J Hepatol 2014 Aug 3;61(2):325-32. Epub 2014 Apr 3.

INSERM, UMR_S 938, Centre de Recherche Saint-Antoine, F-75012 Paris, France; UPMC, Univ Paris 06, UMR_S 938, Centre de Recherche Saint-Antoine, F-75012 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2014.03.033DOI Listing
August 2014

Baseline values and changes in liver stiffness measured by transient elastography are associated with severity of fibrosis and outcomes of patients with primary sclerosing cholangitis.

Gastroenterology 2014 Apr 31;146(4):970-9; quiz e15-6. Epub 2013 Dec 31.

Service d'Hépatologie, Centre de Référence des Maladies Inflammatoires des Voies Biliaires, Hôpital Saint-Antoine, Assistance-Publique Hôpitaux de Paris, Paris, France; INSERM, UMR_S938, CDR Saint-Antoine, Université Pierre et Marie Curie Paris 6, Paris, France.

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http://dx.doi.org/10.1053/j.gastro.2013.12.030DOI Listing
April 2014

Hepatic myofibroblasts promote the progression of human cholangiocarcinoma through activation of epidermal growth factor receptor.

Hepatology 2013 Dec 25;58(6):2001-11. Epub 2013 Oct 25.

Inserm, UMRS 938, Centre de Recherche Saint-Antoine, Paris, France; UPMC, Univ Paris 06, UMRS 938, Centre de Recherche Saint-Antoine, Paris, France.

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http://dx.doi.org/10.1002/hep.26585DOI Listing
December 2013

Primary biliary cirrhosis: is there still a place for histological evaluation?

Clin Res Hepatol Gastroenterol 2013 Dec 8;37(6):556-8. Epub 2013 Aug 8.

Service d'hépatologie, centre de référence des maladies inflammatoires des voies biliaires, hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2013.07.008DOI Listing
December 2013

[The inter-university learning website: a national university network for online teaching of pathology].

Ann Pathol 2013 Jun 28;33(3):162-8. Epub 2013 May 28.

Service d'anatomie et cytologie pathologiques, université de Lorraine, hôpital Central, CHU de Nancy, 29, avenue du Maréchal-De-Lattre-de-Tassigny, 54000 Nancy, France.

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http://dx.doi.org/10.1016/j.annpat.2013.04.004DOI Listing
June 2013

Noninvasive elastography-based assessment of liver fibrosis progression and prognosis in primary biliary cirrhosis.

Hepatology 2012 Jul 5;56(1):198-208. Epub 2012 Jun 5.

Service d'Hépatologie, Centre de référence des Maladies Inflammatoires des Voies Biliaires, Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France.

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http://doi.wiley.com/10.1002/hep.25599
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http://dx.doi.org/10.1002/hep.25599DOI Listing
July 2012

Aspects of liver pathology in adult patients with MDR3/ABCB4 gene mutations.

Virchows Arch 2012 Mar 14;460(3):291-8. Epub 2012 Feb 14.

Service d'Anatomie Pathologique, APHP, Hôpital St Antoine, 75012 Paris, France.

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http://dx.doi.org/10.1007/s00428-012-1202-6DOI Listing
March 2012

A gouty tophus appearing as an atypical liver nodule in a cirrhotic patient.

Clin Res Hepatol Gastroenterol 2011 Dec 24;35(12):855-6. Epub 2011 Oct 24.

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http://dx.doi.org/10.1016/j.clinre.2011.09.003DOI Listing
December 2011

[Liver disease associated with hereditary defects of hepatobiliary transporters].

Authors:
Dominique Wendum

Ann Pathol 2010 Dec 11;30(6):426-31. Epub 2010 Nov 11.

Hôpital Saint-Antoine, AP-HP, Paris, France.

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http://dx.doi.org/10.1016/j.annpat.2010.08.025DOI Listing
December 2010

Imprint cytology in tumor tissue bank quality control: an efficient method to evaluate tumor necrosis and to detect samples without tumor cells.

Virchows Arch 2010 Apr 27;456(4):443-7. Epub 2010 Feb 27.

Service d'Anatomie et Cytologie Pathologiques, AP-HP, Hôpital Saint-Antoine, 184 rue du faubourg St Antoine, 75571 Paris Cedex 12, France.

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http://dx.doi.org/10.1007/s00428-010-0889-5DOI Listing
April 2010

IGF-1R contributes to stress-induced hepatocellular damage in experimental cholestasis.

Am J Pathol 2009 Aug 23;175(2):627-35. Epub 2009 Jul 23.

Inserm UMR_S 938, CdR Saint-Antoine, Faculté de Médecine Pierre et Marie Curie, Site Saint-Antoine, 27 rue Chaligny, 75012 Paris, France.

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http://dx.doi.org/10.2353/ajpath.2009.081081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716962PMC
August 2009

[Primary biliary cirrhosis and the overlap syndrome of primary biliary cirrhosis and autoimmune hepatitis].

Authors:
Dominique Wendum

Ann Pathol 2008 Nov 15;28 Spec No 1(1):S54-5. Epub 2008 Oct 15.

Service d'anatomie pathologique, faculté de médecine Pierre-et-Marie-Curie Paris-6, hôpital Saint-Antoine, UPMC, AP-HP, 184, rue du faubourg Saint-Antoine, 75012 Paris, France.

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http://linkinghub.elsevier.com/retrieve/pii/S024264980800222
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http://dx.doi.org/10.1016/j.annpat.2008.09.014DOI Listing
November 2008

Hypoxia-induced changes in the expression of rat hepatobiliary transporter genes.

Am J Physiol Gastrointest Liver Physiol 2007 Jul;293(1):G25-35

INSERM U680, Faculté de Médecine Pierre et Marie Curie, Site Saint-Antoine, 27 rue Chaligny, 75571 Paris Cedex 12, France.

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http://dx.doi.org/10.1152/ajpgi.00175.2006DOI Listing
July 2007

[A dazzling image].

Ann Pathol 2007 Jun;27(3):251-2

Service d'Anatomie et Cytologie Pathologiques, AP-HP, Hôpital Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75571 Paris cedex 12.

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June 2007

Chronic hepatitis B virus carriers in the immunotolerant phase of infection: histologic findings and outcome.

Clin Gastroenterol Hepatol 2007 May 11;5(5):636-41. Epub 2007 Apr 11.

Assistance Publique-Hôpitaux de Paris, Hôpital Saint Antoine, Service d'Hépatologie, Paris, France.

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http://dx.doi.org/10.1016/j.cgh.2007.01.005DOI Listing
May 2007

Liver adenomatosis: classification of MR imaging features and comparison with pathologic findings.

Radiology 2006 Nov 11;241(2):433-40. Epub 2006 Sep 11.

Department of Radiology, Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France.

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http://dx.doi.org/10.1148/radiol.2412051243DOI Listing
November 2006

Identification of a novel 974C-->G nonsense mutation of the MRP2/ABCC2 gene in a patient with Dubin-Johnson syndrome and analysis of the effects of rifampicin and ursodeoxycholic acid on serum bilirubin and bile acids.

Am J Gastroenterol 2006 Oct 4;101(10):2427-32. Epub 2006 Sep 4.

Service d'Hépatologie, Centre National deRéférence des Maladies Inflammatoires du Foie et des Voies Biliaires, Hôpital Saint-Antoine, Paris, France.

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http://dx.doi.org/10.1111/j.1572-0241.2006.00695.xDOI Listing
October 2006

Association between ABO blood group and fibrosis severity in chronic hepatitis C infection.

Dig Dis Sci 2006 Sep 22;51(9):1633-6. Epub 2006 Aug 22.

Service d'Hépatologie, Hôpital Saint-Antoine Assistance Publique-Hôpitaux de Paris, Université Pierre et Marie Curie, 184 rue du faubourg Saint Antoine, 75012 Paris, France.

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http://dx.doi.org/10.1007/s10620-006-9121-5DOI Listing
September 2006

Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC.

Hepatology 2006 May;43(5):1118-24

Service d'Hépatologie, Centre national de référence des maladies inflammatoires du foie et des voies biliaires, Hôpital Saint-Antoine, Paris, France.

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http://doi.wiley.com/10.1002/hep.21151
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http://dx.doi.org/10.1002/hep.21151DOI Listing
May 2006

Long term outcome and response to therapy of primary biliary cirrhosis-autoimmune hepatitis overlap syndrome.

J Hepatol 2006 Feb 15;44(2):400-6. Epub 2005 Nov 15.

Centre de référence des maladies inflammatoires du foie et des voies biliaires, Hôpital Saint Antoine, Assistance Publique-Hôpitaux de Paris, Faculté de Médecine Pierre et Marie Curie, Paris, France.

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http://dx.doi.org/10.1016/j.jhep.2005.10.017DOI Listing
February 2006

Chronic liver injury during obstructive sleep apnea.

Hepatology 2005 Jun;41(6):1290-6

Service d'Hépatologie, Hôpital Saint-Antoine, Assistance Publique des Hôpitaux de Paris, Paris, France.

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http://dx.doi.org/10.1002/hep.20725DOI Listing
June 2005

Increased lung metastasis in transgenic NM23-Null/SV40 mice with hepatocellular carcinoma.

J Natl Cancer Inst 2005 Jun;97(11):836-45

Unité Institut National de la Santé et de la Recherche Médicale 680, Faculté de Médecine Saint-Antoine, Université Pierre et Marie Curie, Paris, France.

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http://dx.doi.org/10.1093/jnci/dji143DOI Listing
June 2005

c-myc-induced hepatocarcinogenesis in the absence of IGF-I receptor.

Int J Cancer 2005 Apr;114(4):668-72

INSERM U402, Faculté de Médecine, Hôpital St-Antoine, Paris, France.

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http://dx.doi.org/10.1002/ijc.20805DOI Listing
April 2005

Acute hepatitis E: a cause of lymphocytic destructive cholangitis.

Hum Pathol 2005 Apr;36(4):436-8

Department of Pathology, Hôpital Saint-Antoine AP-HP, 75571 Paris Cedex 12, France.

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http://dx.doi.org/10.1016/j.humpath.2005.01.006DOI Listing
April 2005

Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis.

Hepatology 2005 Feb;41(2):307-14

INSERM Unit 402, Faculté de Médecine Saint-Antoine et Université Pierre et Marie Curie, Paris, France.

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http://dx.doi.org/10.1002/hep.20538DOI Listing
February 2005

Adaptative bile duct proliferative response in experimental bile duct ischemia.

J Hepatol 2005 Feb;42(2):257-65

INSERM U402, Faculté de Médecine Saint-Antoine, Université Pierre et Marie Curie, 27 rue Chaligny, 75571 Paris Cedex 12, France.

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http://dx.doi.org/10.1016/j.jhep.2004.10.025DOI Listing
February 2005

Impact of steatosis on progression of fibrosis in patients with mild hepatitis C.

Hepatology 2005 Jan;41(1):82-7

Service d'Hépatologie, Hôpital Saint-Antoine, Paris, France.

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http://doi.wiley.com/10.1002/hep.20519
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http://dx.doi.org/10.1002/hep.20519DOI Listing
January 2005

Cyclooxygenase-2 and its role in colorectal cancer development.

Virchows Arch 2004 Oct 1;445(4):327-33. Epub 2004 Sep 1.

Service d'Anatomie Pathologique, Hôpital Saint-Antoine, AP-HP, 184 rue du Faubourg Saint-Antoine, 75571, Paris Cedex 12, France.

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http://dx.doi.org/10.1007/s00428-004-1105-2DOI Listing
October 2004

Expression of inflammatory secretory phospholipase A2 and cytosolic phospholipase A2 in premalignant and malignant Barrett's oesophagus.

Virchows Arch 2004 May 25;444(5):426-35. Epub 2004 Mar 25.

Service d'Anatomie Pathologique, Hôpital Avicenne, AP-HP, Bobigny, France.

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http://dx.doi.org/10.1007/s00428-004-1003-7DOI Listing
May 2004

[Liver involvement revealing systemic mastocytosis: report of two cases].

Gastroenterol Clin Biol 2004 Jan;28(1):80-3

Service d'Anatomie et cytologie pathologiques, Hôpital Jean Verdier, AP-HP, Avenue du 14 juillet, 93143 Bondy Cedex.

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January 2004

[Quality assessment of intraoperative frozen sections in a teaching hospital: an analysis of 847 consecutive cases].

Ann Pathol 2003 Oct;23(5):393-9

Service d'Anatomie et Cytologie Pathologiques, Hôpital Saint-Antoine AP-HP, 184 rue du faubourg Saint-Antoine, 75571 Paris 12.

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October 2003

[An increasing cholestasis].

Ann Pathol 2003 Sep;23(4):366-7

Service d'Anatomie Pathologique, Hôpital Saint-Antoine, 75571 Paris Cedex 12.

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September 2003

[Diseases of the intrahepatic bile duct: diagnosis and principles of treatment].

Gastroenterol Clin Biol 2003 Mar;27(3 Pt 1):307-18

Service d'Hépatologie, Hôpital Saint-Antoine, 184, rue du Faubourg Saint-Antoine, 75571 Paris Cedex 12.

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March 2003

The myofibroblastic conversion of peribiliary fibrogenic cells distinct from hepatic stellate cells is stimulated by platelet-derived growth factor during liver fibrogenesis.

Lab Invest 2003 Feb;83(2):163-73

Institut National de la Santé et de la Recherche Médicale Unité 402, Faculté de Médecine Saint-Antoine, Hôpital Saint-Antoine, and Service AP-HP de Biochimie (CH), Hôpital Tenon, Paris, France.

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February 2003