Dominique Mottier

Dominique Mottier

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Dominique Mottier

Dominique Mottier

Publications by authors named "Dominique Mottier"

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Validation of risk assessment models predicting venous thromboembolism in acutely ill medical inpatients: a cohort study.

J Thromb Haemost 2020 Mar 13. Epub 2020 Mar 13.

Département de Médecine d'Urgence, CHU d'Angers, Université d'Angers, Institut MITOVASC, UMR CNRS 6015 UMR INSERM 1083, InnoVTE F-CRIN, Angers, France.

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http://dx.doi.org/10.1111/jth.14796DOI Listing
March 2020

Blood anti-Müllerian hormone is a possible determinant of recurrent early miscarriage, yet not conclusive in predicting a further miscarriage.

Reprod Biomed Online 2019 Aug 12;39(2):304-311. Epub 2019 Apr 12.

EA 3878 (GETBO), Department of Internal Medicine and Chest Diseases, Brest University Hospital, Brest, France. Electronic address:

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http://dx.doi.org/10.1016/j.rbmo.2019.04.004DOI Listing
August 2019

Patent Foramen Ovale and Ischemic Stroke in Patients With Pulmonary Embolism: A Prospective Cohort Study.

Ann Intern Med 2019 06 7;170(11):756-763. Epub 2019 May 7.

Brest University Hospital, Western Brittany University, Brest, France (E.L., S.T., D.B., R.D., Y.J., R.L., C.H., A.D., G.L., K.L., C.L., D.M., F.C.).

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http://dx.doi.org/10.7326/M18-3485DOI Listing
June 2019

Incidence and impact of atrial arrhythmias on thrombotic events in MPNs.

Ann Hematol 2018 Jan 21;97(1):101-107. Epub 2017 Nov 21.

Service d'Hématologie Clinique, Institut de Cancéro-Hématologie, Hôpital Morvan, CHRU de Brest, Avenue Foch, 29609, Brest Cedex, France.

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http://dx.doi.org/10.1007/s00277-017-3164-xDOI Listing
January 2018

Administration of direct oral anticoagulants in patients with myeloproliferative neoplasms.

Int J Hematol 2017 Oct 16;106(4):517-521. Epub 2017 Jun 16.

INSERM EA-3878, GETBO (Groupe d'étude de la thrombose en Bretagne occidentale), CHRU de Brest, Brest, France.

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http://dx.doi.org/10.1007/s12185-017-2282-5DOI Listing
October 2017

Association between hospitalization for acute medical illness and VTE risk: A lower efficacy of thromboprophylaxis in elderly patients? Results from the EDITH case-control study.

Eur J Intern Med 2017 Oct 22;44:39-43. Epub 2017 Jun 22.

Brest University, GETBO EA 3878, Brest, F-29609, France; CHU Brest, Hôpital Cavale Blanche, Department of Internal Medicine and Chest Diseases, Brest F-29609, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2017.05.029DOI Listing
October 2017

Risk of recurrent venous thromboembolism in COPD patients: results from a prospective cohort study.

Eur Respir J 2017 07 27;50(1). Epub 2017 Jul 27.

Dept de Médecine Interne et Pneumologie, Hôpital La Cavale Blanche, Brest, France

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http://dx.doi.org/10.1183/13993003.00094-2017DOI Listing
July 2017

JAK2V617F and calreticulin mutations in recurrent venous thromboembolism: results from the EDITH prospective cohort.

Ann Hematol 2017 Mar 20;96(3):383-386. Epub 2016 Oct 20.

Institut National de la Santé et de la Recherche Médicale (INSERM), EA-3878 G.E.T.B.O. (Groupe d'Etude de la Thrombose en Bretagne Occidentale), Brest, France.

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http://dx.doi.org/10.1007/s00277-016-2853-1DOI Listing
March 2017

Current incidence of venous thromboembolism and comparison with 1998: a community-based study in Western France.

Thromb Haemost 2016 Oct 28;116(5):967-974. Epub 2016 Jul 28.

Aurélien Delluc, MD, PhD, EA 3878, Département de Médecine interne et de pneumologie, Centre hospitalier universitaire de Brest, Hôpital de la Cavale Blanche, 29609 Brest Cedex, France, Tel.: +33 2 98 34 73 36, Fax: +33 2 98 34 78 12, E-mail:

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http://dx.doi.org/10.1160/TH16-03-0205DOI Listing
October 2016

Absence of CALR mutation among a cohort of 394 unselected patients with a first episode of unprovoked venous thromboembolism.

Thromb Haemost 2016 Jan 20;115(1):225-6. Epub 2015 Aug 20.

Jean-Christophe Ianotto, Service d'Hématologie Clinique, Institut de Cancéro-Hématologie, Hôpital Morvan - CHRU Brest, 29609 Brest Cedex, France, Tel.: +33 298223504, Fax: +33 298223223, E-mail

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http://dx.doi.org/10.1160/TH15-02-0134DOI Listing
January 2016

Risk of recurrent venous thromboembolism on progestin-only contraception: a cohort study.

Haematologica 2016 Jan 9;101(1):e12-4. Epub 2015 Oct 9.

Department of Internal Medicine and Chest Diseases Brest University Hospital, France EA 3878, Brest University, France INSERM CIC 1412 Clinical Investigation Center, Brest University Hospital, France.

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http://excellence.acforum.org/sites/default/files/predicting
Web Search
http://www.haematologica.org/cgi/doi/10.3324/haematol.2015.1
Publisher Site
http://dx.doi.org/10.3324/haematol.2015.134882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697900PMC
January 2016

Thrombophilia and the Risk of Recurrent Venous Thromboembolism--Reply.

JAMA 2015 Nov;314(18):1976

Centre Hospitalo-Universitaire de Brest, Brest, France.

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http://dx.doi.org/10.1001/jama.2015.12610DOI Listing
November 2015

Six Months vs Extended Oral Anticoagulation After a First Episode of Pulmonary Embolism: The PADIS-PE Randomized Clinical Trial.

JAMA 2015 Jul;314(1):31-40

Département de Médecine Interne et Pneumologie, Centre Hospitalo-Universitaire de Brest, Université de Bretagne Occidentale, and EA 3878, CIC INSERM 1412, Brest, France2Groupe d'Investigation et de Recherche Clinique sur la Thrombose (GIRC Thrombose).

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http://dx.doi.org/10.1001/jama.2015.7046DOI Listing
July 2015

Factors that predict thrombosis in relatives of patients with venous thromboembolism.

Blood 2014 Sep 21;124(13):2124-30. Epub 2014 Jul 21.

McMaster University and the Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada;

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http://dx.doi.org/10.1182/blood-2014-03-559757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186541PMC
September 2014

Prevalence of antiphospholipid antibodies in psychiatric patients users and non-users of antipsychotics.

Br J Haematol 2014 Jan 5;164(2):272-9. Epub 2013 Nov 5.

Université de Bretagne Occidentale, EA 3878 (GETBO), Brest, France; Département de Médecine Interne et Pneumologie, CHRU Brest, Brest, France.

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http://dx.doi.org/10.1111/bjh.12627DOI Listing
January 2014

Unexplained pregnancy loss: a marker of basal endothelial dysfunction?

Fertil Steril 2013 Oct 2;100(4):1013-7. Epub 2013 Jul 2.

EA 3878 (GETBO), Department of Internal Medicine and Chest Diseases, Brest University Hospital, La Cavale Blanche Hospital, Brest, France. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2013.06.008DOI Listing
October 2013

Risk of recurrent venous thromboembolism among young women after a first event while exposed to combined oral contraception versus not exposed to: a cohort study.

Thromb Res 2013 Jul 18;132(1):51-5. Epub 2013 Jun 18.

Department of Internal Medicine and Chest Diseases Brest University Hospital, Brest, F-29609 France.

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http://dx.doi.org/10.1016/j.thromres.2013.05.028DOI Listing
July 2013

Lipid lowering drugs and the risk of recurrent venous thromboembolism.

Thromb Res 2012 Dec 30;130(6):859-63. Epub 2012 Aug 30.

Université de Bretagne Occidentale, EA 3878, Brest, F-29609 France.

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http://dx.doi.org/10.1016/j.thromres.2012.08.296DOI Listing
December 2012

Incidence of venous thromboembolism in psychiatric units.

Thromb Res 2012 Dec 23;130(6):e283-8. Epub 2012 Oct 23.

Université de Bretagne Occidentale, EA 3878, Brest, F-29609 France.

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http://dx.doi.org/10.1016/j.thromres.2012.10.002DOI Listing
December 2012

New anticoagulants in the treatment of VTE.

Semin Respir Crit Care Med 2012 Apr 30;33(2):191-8. Epub 2012 May 30.

Université Européenne de Bretagne, Centre d'investigation clinique, Hôpital de la Cavale Blanche, Boulevard Tanguy Prigent, Brest Cedex, France.

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http://dx.doi.org/10.1055/s-0032-1311799DOI Listing
April 2012

Lipid parameters, lipid lowering drugs and the risk of venous thromboembolism.

Atherosclerosis 2012 Jan 14;220(1):184-8. Epub 2011 Oct 14.

Brest University, GETBO EA 3878, Brest Cedex F-29609, France.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.10.007DOI Listing
January 2012

Site of venous thromboembolism and prothrombotic mutations according to body mass index. Results from the EDITH study.

Br J Haematol 2011 Aug 14;154(4):486-91. Epub 2011 Jun 14.

Université Européenne de Bretagne EA 3878, IFR 148, Université de Brest, 29609 Brest, France.

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http://dx.doi.org/10.1111/j.1365-2141.2011.08592.xDOI Listing
August 2011

Venous thromboembolism in patients with pancreatic cancer: implications of circulating tissue factor.

Blood Coagul Fibrinolysis 2011 Jun;22(4):295-300

Département de Médecine Interne et Pneumologie, Faculté de Médecine et des Sciences de la Santé, Université de Brest, CHU de Brest, Brest, France.

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http://dx.doi.org/10.1097/MBC.0b013e32834512f4DOI Listing
June 2011

Increased thrombin generation measured in the presence of thrombomodulin in women with early pregnancy loss.

Fertil Steril 2011 Apr 3;95(5):1813-5.e1. Epub 2010 Dec 3.

Department of Internal Medicine and Chest Diseases, Brest University Hospital, La Cavale Blanche Hospital, Brest, France.

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http://dx.doi.org/10.1016/j.fertnstert.2010.11.019DOI Listing
April 2011

Factors that predict risk of thrombosis in relatives of patients with unprovoked venous thromboembolism.

Chest 2009 Dec 10;136(6):1537-1545. Epub 2009 Jul 10.

McMaster University and the Henderson Research Centre, Hamilton, ON, Canada.

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http://dx.doi.org/10.1378/chest.09-0757DOI Listing
December 2009

[Clinical prediction rule for diagnosing deep vein thrombosis in primary care].

Presse Med 2009 Apr 4;38(4):525-33. Epub 2008 Dec 4.

Médecin généraliste, F-22940 Plaintel, France.

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http://dx.doi.org/10.1016/j.lpm.2008.09.022DOI Listing
April 2009

Family history as a risk factor for venous thromboembolism.

Thromb Res 2008 20;122(5):624-9. Epub 2008 Feb 20.

Faculté de Médecine et des Sciences de la Santé de Brest, Université de Bretagne, Occidentale (UBO), Brest, France.

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http://dx.doi.org/10.1016/j.thromres.2007.12.026DOI Listing
December 2008

Primary prevention of venous thromboembolism in elderly medical patients.

Clin Interv Aging 2008 ;3(3):399-411

GETBO EA 3878, CHU de Brest, Department of Internal Medicine and Chest Diseases, Hôpital Cavale Blanche, Brest, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682373PMC
http://dx.doi.org/10.2147/cia.s832DOI Listing
December 2008

Management of suspected pulmonary embolism patients with low clinical and low V/Q probability.

Thromb Res 2008 18;122(4):450-4. Epub 2007 Dec 18.

Département de Médecine Interne et de Pneumologie, Centre Hospitalier Universitaire de la Cavale Blanche, 29609 Brest Cedex, France.

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https://linkinghub.elsevier.com/retrieve/pii/S00493848070039
Publisher Site
http://dx.doi.org/10.1016/j.thromres.2007.10.024DOI Listing
November 2008

Differential associations between lipid-lowering drugs, statins and fibrates, and venous thromboembolism: role of drug induced homocysteinemia?

Thromb Res 2008 28;122(3):314-9. Epub 2007 Nov 28.

Brest University, GETBO EA 3878, EPI-PHARM, Brest, F-29609, France.

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http://dx.doi.org/10.1016/j.thromres.2007.10.014DOI Listing
October 2008

Fibrinogen Aalpha-Thr312Ala and factor XIII-A Val34Leu polymorphisms in idiopathic venous thromboembolism.

Thromb Res 2007 12;121(3):333-8. Epub 2007 Jun 12.

EA 3878, Department of Internal Medicine and Chest Diseases, Brest University Hospital, Brest, France.

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http://dx.doi.org/10.1016/j.thromres.2007.05.003DOI Listing
April 2008

Thrombin generation in first-degree relatives of patients with venous thromboembolism who have factor V Leiden. A pilot study.

Thromb Haemost 2008 Jan;99(1):223-8

G.E.T.B.O. (Groupe d'Etude de la Thrombose de Bretagne Occidentale), EA 3878, Department of Internal Medicine and Chest Diseases, University Hospital of Brest, Brest, France.

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http://dx.doi.org/10.1160/TH07-08-0515DOI Listing
January 2008

Interrelation of hyperhomocysteinemia and inherited risk factors for venous thromboembolism. Results from the E.D.I.TH. study: a hospital-based case-control study.

Thromb Res 2007 28;120(2):207-14. Epub 2006 Nov 28.

G.E.T.B.O. EA-3878 (Groupe d'Etude de la Thrombose de Bretagne Occidentale), Department of Internal Medicine and Chest Diseases, Brest University Hospital, 29609 Brest Cedex, France.

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http://dx.doi.org/10.1016/j.thromres.2006.10.002DOI Listing
July 2007

Antiplatelet drug use preceding the onset of intracerebral hemorrhage is associated with increased mortality.

Fundam Clin Pharmacol 2007 Jun;21(3):327-33

Department of Internal Medicine and Chest Diseases, G.E.T.B.O. (Groupe d'Etude de la Thrombose de Bretagne Occidentale), Brest Cedex, France.

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http://dx.doi.org/10.1111/j.1472-8206.2007.00488.xDOI Listing
June 2007

[Incidence and risk factors for venous thromboembolism].

Rev Prat 2007 Apr;57(7):711-3, 716, 719-20

Université de Bretagne occidentale, GETBO EA-3878, hôpital de la Cavale-Blanche, 29609 Brest.

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April 2007

[Do observational studies have a role in assessing treatment?].

Presse Med 2007 Mar 30;36(3 Pt 2):536-40. Epub 2007 Jan 30.

EA 3878 (Groupe d'étude de la thrombose de Bretagne occidentale), Département de Médecine Interne et de Pneumologie, CHU de la Cavale Blanche, Brest.

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http://dx.doi.org/10.1016/j.lpm.2007.01.014DOI Listing
March 2007

Incidence of venous thromboembolism in first-degree relatives of patients with venous thromboembolism who have factor V Leiden.

Thromb Haemost 2006 Dec;96(6):744-9

GETBO, EA 3878, Department of Internal Medicine and Chest Diseases, University Hospital Centre La Cavale Blanche, 29609 Brest, Cedex, France.

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December 2006

[Deep venous thrombosis and pulmonary embolism].

Rev Prat 2005 Nov;55(18):2071-9

Groupe d'études de la thrombose de Bretagne occidentale, EA 38 78, CHRU de la Cavale Blanche, 29609 Brest Cedex.

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November 2005

Management of suspected venous thromboembolism: the impact of a multifaceted intervention.

Int J Qual Health Care 2005 Oct 4;17(5):433-8. Epub 2005 May 4.

Groupe d'Etude de la Thrombose de Bretagne Occidentale (GETBO), Hôpital de la Cavale Blanche, F-29609 Brest Cedex, France.

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http://dx.doi.org/10.1093/intqhc/mzi050DOI Listing
October 2005

Statins but not fibrates are associated with a reduced risk of venous thromboembolism: a hospital-based case-control study.

Fundam Clin Pharmacol 2004 Aug;18(4):477-82

Groupe d'Etude de la Thrombose de Bretagne Occidentale (GETBO), Department of Internal Medicine and Chest Diseases, Hôpital de la Cavale Blanche, 29609 Brest Cedex, France.

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http://doi.wiley.com/10.1111/j.1472-8206.2004.00252.x
Publisher Site
http://dx.doi.org/10.1111/j.1472-8206.2004.00252.xDOI Listing
August 2004

[Diagnosis of postoperative venous thromboembolism].

Presse Med 2003 May;32(18):852-9

G.E.T.B.O (Groupe d'Etude de la Thrombose de Bretagne Occidentale), Département de médecine interne et pneumologie, Hôpital de la Cavale Blanche, 29609 Brest.

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May 2003

High plasma concentration of factor VIII coagulant is also a risk factor for venous thromboembolism in the elderly.

Haematologica 2003 Apr;88(4):465-9

Department of Internal Medicine and Chest Diseases, Hôpital de la Cavale Blanche, F-29609 Brest Cedex, France.

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April 2003

Is APC resistance a risk factor for venous thromboembolism in patients over 70 years?

Thromb Haemost 2002 Oct;88(4):587-91

Groupe d'Etude de la Thrombose de Bretagne Occidentale, Department of Internal Medicine and Chest Diseases, Hôpital de la Cavale Blanche, F-29609 Brest Cedex, France.

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October 2002

High prevalence of asymptomatic deep vein thrombosis on admission in a medical unit among elderly patients.

Thromb Haemost 2002 Oct;88(4):592-7

Groupe d'Etude de la Thrombose de Bretagne Occidentale, Department of Internal Medecine and Chest Diseases, Hôpital de la Cavale Blanche, F-29609 Brest Cedex, France.

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October 2002

[Effect of stressful life events on clinical development of temporal arteritis and/or polymyalgia rheumatica].

Presse Med 2002 Jun;31(19):873-9

Service de médecine interne 4, CHU de la Cavale Blanche, Avenue Tanguy Prigent, 29 609 Brest.

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June 2002