Dominique Langin

Dominique Langin

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Dominique Langin

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Niacin induces miR-502-3p expression which impairs insulin sensitivity in human adipocytes.

Int J Obes (Lond) 2018 Nov 27. Epub 2018 Nov 27.

Institut National de la Santé et de la Recherche Médicale (Inserm), UMR1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases (I2MC), Toulouse, France.

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http://www.nature.com/articles/s41366-018-0260-5
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http://dx.doi.org/10.1038/s41366-018-0260-5DOI Listing
November 2018

FADS1 genotype is distinguished by human subcutaneous adipose tissue fatty acids, but not inflammatory gene expression.

Int J Obes (Lond) 2018 Aug 6. Epub 2018 Aug 6.

Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada.

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http://dx.doi.org/10.1038/s41366-018-0169-zDOI Listing
August 2018

Caloric Restriction and Diet-Induced Weight Loss Do Not Induce Browning of Human Subcutaneous White Adipose Tissue in Women and Men with Obesity.

Cell Rep 2018 01 28;22(4):1079-1089. Epub 2018 Jan 28.

INSERM, UMR 1048, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France; University of Toulouse, Paul Sabatier University, Toulouse, France; Toulouse University Hospitals, Laboratory of Clinical Biochemistry, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.12.102DOI Listing
January 2018

Molecular Biomarkers for Weight Control in Obese Individuals Subjected to a Multiphase Dietary Intervention.

J Clin Endocrinol Metab 2017 08;102(8):2751-2761

Institut National de la Santé et de la Recherche Médicale, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, 31432 Toulouse, France.

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http://dx.doi.org/10.1210/jc.2016-3997DOI Listing
August 2017

Control of adipogenesis by oxylipins, GPCRs and PPARs.

Biochimie 2017 May 27;136:3-11. Epub 2016 Dec 27.

Université Côte d'Azur, CNRS, Inserm, iBV, France. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2016.12.012DOI Listing
May 2017

Comparison of Early (2 Days) and Later (28 Days) Response of Adipose Tissue to Very Low-Calorie Diet in Obese Women.

J Clin Endocrinol Metab 2016 12 7;101(12):5021-5029. Epub 2016 Oct 7.

Department of Sport Medicine (V.Š., L.R., E.K., J.K., M.K., V.Š., M.Š.), Third Faculty of Medicine, Charles University, 100 00 Prague 10, Czech Republic; Franco-Czech Laboratory for Clinical Research on Obesity (V.Š., L.R., E.K., J.K., M.K., D.L., V.Š., M.Š.), Third Faculty of Medicine, Prague, and Institut des Maladies Métaboliques et Cardiovasculaires, Université Toulouse III Paul Sabatier, Unité Mixte de Recherche, F-31432 Toulouse, France; Second Department of Internal Medicine (E.K., V.Š.), University Hospital Kralovske Vinohrady, 100 34 Prague, Czech Republic; and INSERM (D.L.), Unité Mixte de Recherche 1048, Institute of Metabolic and Cardiovascular Diseases, and University of Toulouse, Paul Sabatier University, and Department of Clinical Biochemistry (D.L.), Toulouse University Hospitals, F-31432 Toulouse, France.

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http://dx.doi.org/10.1210/jc.2016-2161DOI Listing
December 2016

Regiocontrolled syntheses of FAHFAs and LC-MS/MS differentiation of regioisomers.

Org Biomol Chem 2016 Oct 6;14(38):9012-20. Epub 2016 Sep 6.

Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, CNRS, Université Montpellier, ENSCM, Faculté de Pharmacie, 15 av. Charles Flahault, 34093 Montpellier Cedex 5, France.

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http://dx.doi.org/10.1039/c6ob01597bDOI Listing
October 2016

G0/G1 Switch Gene 2 controls adipose triglyceride lipase activity and lipid metabolism in skeletal muscle.

Mol Metab 2016 Jul 22;5(7):527-537. Epub 2016 Apr 22.

INSERM, UMR1048, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France; University of Toulouse, Paul Sabatier University, France. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2016.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921782PMC
July 2016

Adipocyte lipolysis and insulin resistance.

Biochimie 2016 Jun 2;125:259-66. Epub 2015 Nov 2.

INSERM, UMR1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France; University of Toulouse, UMR1048, Paul Sabatier University, France; Toulouse University Hospitals, Department of Clinical Biochemistry, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2015.10.024DOI Listing
June 2016

Defective Natriuretic Peptide Receptor Signaling in Skeletal Muscle Links Obesity to Type 2 Diabetes.

Diabetes 2015 Dec 7;64(12):4033-45. Epub 2015 Aug 7.

Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, INSERM, UMR1048, Toulouse, France University of Toulouse, UMR1048, Paul Sabatier University, Toulouse, France

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http://dx.doi.org/10.2337/db15-0305DOI Listing
December 2015

Fatty acids from fat cell lipolysis do not activate an inflammatory response but are stored as triacylglycerols in adipose tissue macrophages.

Diabetologia 2015 Nov 6;58(11):2627-36. Epub 2015 Aug 6.

Inserm, UMR1048, Institute of Metabolic and Cardiovascular Diseases, I2MC, Obesity Research Laboratory, Team 4, CHU Rangueil, 1 avenue Jean Poulhès, BP 84225, 31432, Toulouse Cedex 4, France.

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http://dx.doi.org/10.1007/s00125-015-3719-0DOI Listing
November 2015

Adipose tissue CIDEA is associated, independently of weight variation, to change in insulin resistance during a longitudinal weight control dietary program in obese individuals.

PLoS One 2014 1;9(7):e98707. Epub 2014 Jul 1.

Institut National de la Santé et de la Recherche Médicale (INSERM), UMR1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases (I2MC), Toulouse, France; University of Toulouse, UMR1048, Paul Sabatier University, Toulouse, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098707PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077708PMC
October 2015

Primary defects in lipolysis and insulin action in skeletal muscle cells from type 2 diabetic individuals.

Biochim Biophys Acta 2015 Sep 24;1851(9):1194-201. Epub 2015 Mar 24.

Inserm, Paul Sabatier University, UMR 1048, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France.

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http://dx.doi.org/10.1016/j.bbalip.2015.03.005DOI Listing
September 2015

MAFB as a novel regulator of human adipose tissue inflammation.

Diabetologia 2015 Sep 27;58(9):2115-23. Epub 2015 Jun 27.

Department of Medicine Huddinge, Lipid laboratory, Karolinska Institutet, Novum, NVS D4, Hälsovägen 7, 14186, Stockholm, Sweden.

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http://link.springer.com/10.1007/s00125-015-3673-x
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http://dx.doi.org/10.1007/s00125-015-3673-xDOI Listing
September 2015

Stress of endoplasmic reticulum modulates differentiation and lipogenesis of human adipocytes.

Biochem Biophys Res Commun 2015 May 24;460(3):684-90. Epub 2015 Mar 24.

Franco-Czech Laboratory for Clinical Research on Obesity, Third Faculty of Medicine, Prague, Czech Republic; Department of Sport Medicine, Third Faculty of Medicine, Charles University in Prague, CZ-100 00, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.03.090DOI Listing
May 2015

Adipose tissue lipases and lipolysis.

Authors:
Dominique Langin

Endocrinol Nutr 2013 ;60 Suppl 1:26-8

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April 2015

α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects.

Biochim Biophys Acta 2015 Mar 24;1851(3):273-81. Epub 2014 Dec 24.

Department of Nutrition, Food Science and Physiology, University of Navarra, Pamplona, Spain; Center for Nutrition Research, University of Navarra, Pamplona, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2014.12.013DOI Listing
March 2015

System model network for adipose tissue signatures related to weight changes in response to calorie restriction and subsequent weight maintenance.

PLoS Comput Biol 2015 Jan 15;11(1):e1004047. Epub 2015 Jan 15.

Institut National de la Santé et de la Recherche Médicale (INSERM), UMR1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases (I2MC), Toulouse, France; University of Toulouse, UMR1048, Paul Sabatier University, Toulouse, France.

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https://dx.plos.org/10.1371/journal.pcbi.1004047
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http://dx.doi.org/10.1371/journal.pcbi.1004047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295881PMC
January 2015

α-lipoic acid reduces fatty acid esterification and lipogenesis in adipocytes from overweight/obese subjects.

Obesity (Silver Spring) 2014 Oct 17;22(10):2210-5. Epub 2014 Jul 17.

Department of Nutrition, Food Science and Physiology, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1002/oby.20846DOI Listing
October 2014

Hormone-sensitive lipase deficiency in humans.

Cell Metab 2014 Aug;20(2):199-201

Inserm, UMR1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, 31432 Toulouse, France; University of Toulouse, Paul Sabatier University, 31062 Toulouse, France; Toulouse University Hospitals, Department of Clinical Biochemistry, 31059 Toulouse, France.

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http://dx.doi.org/10.1016/j.cmet.2014.07.018DOI Listing
August 2014

Positive interaction between prebiotics and thiazolidinedione treatment on adiposity in diet-induced obese mice.

Obesity (Silver Spring) 2014 Jul 19;22(7):1653-61. Epub 2014 Apr 19.

Nutrition and Metabolism Research Group, LDRI, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/oby.20733DOI Listing
July 2014

Influence of lipolysis and fatty acid availability on fuel selection during exercise.

J Physiol Biochem 2014 Jun 15;70(2):583-91. Epub 2013 Dec 15.

Inserm UMR1048, Institute of Metabolic and Cardiovascular Diseases, Obesity Research Laboratory, CHU Rangueil, 1 Avenue Jean Poulhès, BP84225, 31432, Toulouse Cedex 4, France,

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http://dx.doi.org/10.1007/s13105-013-0306-zDOI Listing
June 2014

Lipolysis in lipid turnover, cancer cachexia, and obesity-induced insulin resistance.

Trends Endocrinol Metab 2014 May 11;25(5):255-62. Epub 2014 Apr 11.

Institut National de la Santé et de la Recherche Médicale (INSERM), Unité Mixte de Recherche (UMR) 1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, 31432 Toulouse, France; University of Toulouse, UMR 1048, Paul Sabatier University, 31432 Toulouse, France; Toulouse University Hospitals, Department of Clinical Biochemistry, 31059 Toulouse, France.

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https://linkinghub.elsevier.com/retrieve/pii/S10432760140004
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http://dx.doi.org/10.1016/j.tem.2014.03.002DOI Listing
May 2014

Immune cell Toll-like receptor 4 mediates the development of obesity- and endotoxemia-associated adipose tissue fibrosis.

Cell Rep 2014 May 1;7(4):1116-29. Epub 2014 May 1.

Franco-Czech Laboratory for Clinical Research on Obesity, Inserm, 31432 Toulouse Cedex 4, France; Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, UMR1048, Inserm, 31432 Toulouse Cedex 4, France; UMR1048, Paul Sabatier University, University of Toulouse, 31432 Toulouse Cedex 4, France; Department of Clinical Biochemistry, Toulouse University Hospitals, 31059 Toulouse Cedex 9, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.03.062DOI Listing
May 2014

Soluble CD163 is associated with CD163 mRNA expression in adipose tissue and with insulin sensitivity in steady-state condition but not in response to calorie restriction.

J Clin Endocrinol Metab 2014 Mar 13;99(3):E528-35. Epub 2014 Jan 13.

Department of Sport Medicine (J.K., L.R., Z.K., E.K., J.P., M.T., L.M., V.S., M.S.) and Franco-Czech Laboratory for Clinical Research on Obesity (J.K., L.R., Z.K., E.K., M.T., L.M., V.S., D.L., M.S.), Third Faculty of Medicine, Charles University, 100 00 Prague 100 00 Czech Republic; INSERM, 31059 Toulouse, France; INSERM, Unité Mixte de Recherche 1048 (D.L.), Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, 31432 Toulouse, France; University of Toulouse, Unité Mixte de Recherche 1048 (D.L.), Paul Sabatier University, 31432 Toulouse, France; and Department of Clinical Biochemistry (D.L.), Toulouse University Hospitals, 31000 Toulouse, France.

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http://dx.doi.org/10.1210/jc.2013-3348DOI Listing
March 2014

Pro-fibrotic activity of lysophosphatidic acid in adipose tissue: in vivo and in vitro evidence.

Biochim Biophys Acta 2014 Jan 11;1841(1):88-96. Epub 2013 Oct 11.

Institut National de la Santé et de la Recherche Médicale (INSERM), UMR1048, Toulouse Cedex 4, France; Université de Toulouse, Université Paul Sabatier, Institut des Maladies Métaboliques et Cardiovasculaires, BP84225, 31432 Toulouse Cedex 4, France.

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http://dx.doi.org/10.1016/j.bbalip.2013.10.003DOI Listing
January 2014

Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.

Circulation 2014 Jan 4;129(4):451-62. Epub 2013 Nov 4.

Institut de Recherche Expérimentale et Clinique (IREC), Pole of Pharmacology and Therapeutics (FATH), Université Catholique de Louvain, Brussels, Belgium (C.B., J. Hammond, E.D.-D., B.M., J. Hamelet, A.M., H.E., K.J., I.L., C.D., J.-L.B.); Pole of Cardiovascular Pathology and Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium (C.B., A.-C.P., L.B.); the Division of Cardiology and Pneumology, University of Goettingen, Goettingen, Germany (K.R.G., V.O.N.); the Department of Cardiovascular Sciences, Katholieke Universiteit Leuven, Belgium (A.V., P.H.); the Department of Medicine and Surgery, University of Salerno and RCCS "Multimedica," Milano, Italy (G.I.); Molecular Cardiology, Medizinische Hochschule Hannover, Germany (D.H.-K.); and Université Paul Sabatier, Inserm UMR 1048 - I2MC, Hôpitaux de Toulouse, France (G.T., D.L.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.004940DOI Listing
January 2014

Dynamics of skeletal muscle lipid pools.

Trends Endocrinol Metab 2013 Dec 26;24(12):607-15. Epub 2013 Aug 26.

Obesity Research Laboratory, Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMR) 1048, Institute of Metabolic and Cardiovascular Diseases (I2MC), Toulouse, France; University of Toulouse, UMR1048, Paul Sabatier University, Toulouse, France.

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http://dx.doi.org/10.1016/j.tem.2013.08.001DOI Listing
December 2013

Endurance exercise training up-regulates lipolytic proteins and reduces triglyceride content in skeletal muscle of obese subjects.

J Clin Endocrinol Metab 2013 Dec 31;98(12):4863-71. Epub 2013 Oct 31.

PhD, Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche 1048, Institut des Maladies Métaboliques et Cardiovasculaires, Centre Hospitalier Universitaire Rangueil, BP 84225, 1 Avenue Jean Poulhès, 31432 Toulouse Cedex 4, France.

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http://dx.doi.org/10.1210/jc.2013-2058DOI Listing
December 2013

Comment on: Sitnick et al. Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. Diabetes 2013;62:3350-3361.

Diabetes 2013 Dec;62(12):e29

INSERM UMR1048, Institute of Metabolic and Cardiovascular Diseases, Obesity Research Laboratory, and Paul Sabatier University, Toulouse, France.

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http://dx.doi.org/10.2337/db13-1107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837070PMC
December 2013

Metabolic syndrome, circulating RBP4, testosterone, and SHBG predict weight regain at 6 months after weight loss in men.

Obesity (Silver Spring) 2013 Oct 25;21(10):1997-2006. Epub 2013 May 25.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands.

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http://dx.doi.org/10.1002/oby.20311DOI Listing
October 2013

Enhanced glucose metabolism is preserved in cultured primary myotubes from obese donors in response to exercise training.

J Clin Endocrinol Metab 2013 Sep 24;98(9):3739-47. Epub 2013 Jul 24.

Institut National de la Santé et de la Recherche Médicale (INSERM), Unité Mixte de Recherche (UMR) 1048, Obesity Research Laboratory, 31432 Toulouse, France.

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http://dx.doi.org/10.1210/jc.2013-1727DOI Listing
September 2013

Weight loss improves the adipogenic capacity of human preadipocytes and modulates their secretory profile.

Diabetes 2013 Jun 1;62(6):1990-5. Epub 2013 Feb 1.

Franco-Czech Laboratory for Clinical Research on Obesity, Third Faculty of Medicine, Prague, Czech Republic, and INSERM, Toulouse, France.

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http://dx.doi.org/10.2337/db12-0986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661637PMC
June 2013

In vitro brown and "brite"/"beige" adipogenesis: human cellular models and molecular aspects.

Biochim Biophys Acta 2013 May 10;1831(5):905-14. Epub 2012 Nov 10.

University of Nice Sophia Antipolis, UFR Sciences, Nice, F-06108, France.

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http://dx.doi.org/10.1016/j.bbalip.2012.11.001DOI Listing
May 2013

High-fat diet-mediated lipotoxicity and insulin resistance is related to impaired lipase expression in mouse skeletal muscle.

Endocrinology 2013 Apr 7;154(4):1444-53. Epub 2013 Mar 7.

Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche 1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, 31432 Toulouse Cedex 4, France.

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http://dx.doi.org/10.1210/en.2012-2029DOI Listing
April 2013

WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4.

Proc Natl Acad Sci U S A 2013 Feb 28;110(7):2563-8. Epub 2013 Jan 28.

Lundberg Laboratory for Diabetes Research, Center of Excellence for Metabolic and Cardiovascular Research, Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, SE-413 45 Gothenburg, Sweden.

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http://dx.doi.org/10.1073/pnas.1211255110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574913PMC
February 2013

Adipose tissue secretion and expression of adipocyte-produced and stromavascular fraction-produced adipokines vary during multiple phases of weight-reducing dietary intervention in obese women.

J Clin Endocrinol Metab 2012 Jul 24;97(7):E1176-81. Epub 2012 Apr 24.

Franco-Czech Laboratory for Clinical Research on Obesity, Third Faculty of Medicine, Prague, CZ-100 00, Czech Republic.

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http://dx.doi.org/10.1210/jc.2011-2380DOI Listing
July 2012

Hidden variant of ChREBP in fat links lipogenesis to insulin sensitivity.

Cell Metab 2012 Jun;15(6):795-7

Inserm U1016, Institut Cochin, 75014 Paris, France.

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http://dx.doi.org/10.1016/j.cmet.2012.05.007DOI Listing
June 2012

Regulation of skeletal muscle lipolysis and oxidative metabolism by the co-lipase CGI-58.

J Lipid Res 2012 May 29;53(5):839-48. Epub 2012 Feb 29.

Inserm 1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, Paul Sabatier University, Toulouse, France.

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http://dx.doi.org/10.1194/jlr.M019182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329383PMC
May 2012

Multiple effects of a short-term dexamethasone treatment in human skeletal muscle and adipose tissue.

Physiol Genomics 2012 Feb 22;44(2):141-51. Epub 2011 Nov 22.

Inserm, UMR1048, Obesity Research Laboratory, Institut des Maladies Métaboliques et Cardiovasculaires, France.

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http://dx.doi.org/10.1152/physiolgenomics.00032.2011DOI Listing
February 2012

Catecholamine and insulin control of lipolysis in subcutaneous adipose tissue during long-term diet-induced weight loss in obese women.

Am J Physiol Endocrinol Metab 2012 Jan 8;302(2):E226-32. Epub 2011 Nov 8.

Department of Sports Medicine, Third Faculty of Medicine, Charles University of Prague, Ruska 87, Prague 10, Czech Republic.

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http://www.physiology.org/doi/10.1152/ajpendo.00240.2011
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http://dx.doi.org/10.1152/ajpendo.00240.2011DOI Listing
January 2012

In and out: adipose tissue lipid turnover in obesity and dyslipidemia.

Authors:
Dominique Langin

Cell Metab 2011 Nov;14(5):569-70

INSERM U1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France.

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http://dx.doi.org/10.1016/j.cmet.2011.10.003DOI Listing
November 2011

Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans.

Diabetes 2011 Jun 15;60(6):1734-42. Epub 2011 Apr 15.

INSERM, U1048, Obesity Research Laboratory, Institute of Metabolicand Cardiovascular Diseases (I2MC), Toulouse, France.

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http://dx.doi.org/10.2337/db10-1364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114384PMC
June 2011

CIDEA interacts with liver X receptors in white fat cells.

FEBS Lett 2011 Mar 22;585(5):744-8. Epub 2011 Feb 22.

Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.febslet.2011.02.004DOI Listing
March 2011

Skeletal muscle lipase content and activity in obesity and type 2 diabetes.

J Clin Endocrinol Metab 2010 Dec 15;95(12):5449-53. Epub 2010 Sep 15.

Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht School for Nutrition, Toxicology, and Metabolism, Maastricht University Medical Centre, P.O. Box 616, 6200 MD Maastricht, The Netherlands.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2010-0776DOI Listing
December 2010

Cyclin G2 regulates adipogenesis through PPAR gamma coactivation.

Endocrinology 2010 Nov 15;151(11):5247-54. Epub 2010 Sep 15.

Institut de Recherche en Cancérologie de Montpellier, CRLC Val d'Aurelle, Parc Euromédecine, F-34298, Montpellier Cedex 5, France.

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http://dx.doi.org/10.1210/en.2010-0461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000854PMC
November 2010

Lipid mobilization in subcutaneous adipose tissue during exercise in lean and obese humans. Roles of insulin and natriuretic peptides.

Am J Physiol Endocrinol Metab 2010 Aug 18;299(2):E258-65. Epub 2010 May 18.

Department of Sports Medicine, Third Faculty of Medicine, Charles University of Prague, Ruska 87, Prague 10, Czech Republic.

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http://www.physiology.org/doi/10.1152/ajpendo.00767.2009
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http://dx.doi.org/10.1152/ajpendo.00767.2009DOI Listing
August 2010

Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese Europeans: the NUGENOB study.

Obesity (Silver Spring) 2010 Jul 29;18(7):1369-77. Epub 2009 Oct 29.

Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1038/oby.2009.377DOI Listing
July 2010

Adipose tissue lipolysis.

Curr Opin Clin Nutr Metab Care 2010 Jul;13(4):377-81

Inserm, Unité 858, Obesity Research Laboratory, Rangueil Institute of Molecular Medicine (I2MR), IFR150, Toulouse, France.

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http://dx.doi.org/10.1097/MCO.0b013e32833bed6aDOI Listing
July 2010

Adipose tissue lipolysis revisited (again!): lactate involvement in insulin antilipolytic action.

Authors:
Dominique Langin

Cell Metab 2010 Apr;11(4):242-3

Inserm U858, Obesity Research Laboratory, Rangueil Institute of Molecular Medicine, Toulouse F-31432, France.

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http://dx.doi.org/10.1016/j.cmet.2010.03.003DOI Listing
April 2010

Recruitment of brown fat and conversion of white into brown adipocytes: strategies to fight the metabolic complications of obesity?

Authors:
Dominique Langin

Biochim Biophys Acta 2010 Mar 24;1801(3):372-6. Epub 2009 Sep 24.

Inserm U858, Laboratoire de recherches sur les obésités, Toulouse, F-31432, France.

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http://linkinghub.elsevier.com/retrieve/pii/S138819810900221
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http://dx.doi.org/10.1016/j.bbalip.2009.09.008DOI Listing
March 2010

Peroxisome proliferator-activated receptor-alpha control of lipid and glucose metabolism in human white adipocytes.

Endocrinology 2010 Jan 3;151(1):123-33. Epub 2009 Nov 3.

Institut National de la Santé et de la Recherche Médicale (INSERM) Unité 858, 1 Avenue Jean Pouilhès, BP 84225, 31432 Toulouse Cedex 4, France.

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http://dx.doi.org/10.1210/en.2009-0726DOI Listing
January 2010

Regulation of adipose tissue lipolysis revisited.

Proc Nutr Soc 2009 Nov 24;68(4):350-60. Epub 2009 Aug 24.

Inserm U858, Laboratoire de Recherches sur les Obésités, F-31432 Toulouse, France.

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http://dx.doi.org/10.1017/S0029665109990279DOI Listing
November 2009

Lipolysis and lipid mobilization in human adipose tissue.

Prog Lipid Res 2009 Sep 21;48(5):275-97. Epub 2009 May 21.

Inserm U, Institut de Médecine Moléculaire de Rangueil, IFR-BMT, Toulouse, France.

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http://dx.doi.org/10.1016/j.plipres.2009.05.001DOI Listing
September 2009

Influence of gender, obesity, and muscle lipase activity on intramyocellular lipids in sedentary individuals.

J Clin Endocrinol Metab 2009 Sep 16;94(9):3440-7. Epub 2009 Jun 16.

Department of Molecular and Experimental Endocrinology, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, Louisiana 70808, USA.

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http://dx.doi.org/10.1210/jc.2009-0053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741707PMC
September 2009

Chronic TNFalpha and cAMP pre-treatment of human adipocytes alter HSL, ATGL and perilipin to regulate basal and stimulated lipolysis.

FEBS Lett 2009 Sep 18;583(18):3045-9. Epub 2009 Aug 18.

Laboratoire de Recherches sur Obésités, Inserm U858, Toulouse, France.

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http://dx.doi.org/10.1016/j.febslet.2009.08.019DOI Listing
September 2009

Secretion of adiponectin multimeric complexes from adipose tissue explants is not modified by very low calorie diet.

Eur J Endocrinol 2009 Apr 20;160(4):585-92. Epub 2009 Jan 20.

Sports Medicine Department, Division of Cell and Molecular Biology, Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1530/EJE-08-0727DOI Listing
April 2009

Contribution of energy restriction and macronutrient composition to changes in adipose tissue gene expression during dietary weight-loss programs in obese women.

J Clin Endocrinol Metab 2008 Nov 9;93(11):4315-22. Epub 2008 Sep 9.

Laboratoire de Recherches sur les Obésités, Institut National de la Santé et de la Recherche Médicale Unit 858-I2MR, Equipe 4, IFR31, Institut Louis Bugnard, 1 Avenue Jean Poulhès, BP 84225, 31432 Toulouse cedex 4, France.

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http://dx.doi.org/10.1210/jc.2008-0814DOI Listing
November 2008

Evidence for an important role of CIDEA in human cancer cachexia.

Cancer Res 2008 Nov;68(22):9247-54

Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1343DOI Listing
November 2008

The transcriptional co-activator PGC-1alpha up regulates apelin in human and mouse adipocytes.

Regul Pept 2008 Oct 13;150(1-3):33-7. Epub 2008 Apr 13.

Institut National de la Santé et de la Recherche Médicale, U858, Toulouse, France.

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http://dx.doi.org/10.1016/j.regpep.2008.04.003DOI Listing
October 2008

Gene expression profiling of human skeletal muscle in response to stabilized weight loss.

Am J Clin Nutr 2008 Jul;88(1):125-32

INSERM, U858, Obesity Research Laboratory, Institut de Médecine Moléculaire de Rangueil, Toulouse, France.

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http://dx.doi.org/10.1093/ajcn/88.1.125DOI Listing
July 2008