Prof. Dominik R Haudenschild, Ph.D. - University of California Davis Medical Center - Professor

Prof. Dominik R Haudenschild

Ph.D.

University of California Davis Medical Center

Professor

Sacramento, CA | United States

Main Specialties: Other

Additional Specialties: Arthritis Research

ORCID logohttps://orcid.org/0000-0001-9947-9864


Top Author

Prof. Dominik R Haudenschild, Ph.D. - University of California Davis Medical Center - Professor

Prof. Dominik R Haudenschild

Ph.D.

Introduction

Biotech Research at Genzyme Tissue Repair
Academic Research at Scripps Research Institute and University of California Davis

Primary Affiliation: University of California Davis Medical Center - Sacramento, CA , United States

Specialties:

Additional Specialties:

Research Interests:


View Prof. Dominik R Haudenschild’s Resume / CV

Education

Sep 1999 - Jun 2003
University of California Davis
Ph.D. in Biochemistry and Molecular Biology
College of Biological Sciences
Jun 2003
University of California Davis
PhD
Biochemistry and Molecular Biology
Jun 1989
Boston University
B.A.

Experience

Jul 2018 - Jul 2018
University of California Davis School of Medicine
Professor
Department of Orthopaedic Surgery
Jul 2014 - Jun 2018
University of California Davis School of Medicine
Associate Professor
Department of Orthopaedic Surgery
Sep 2008 - Jun 2014
University of California Davis School of Medicine
Assistant Professor
Department of Orthopaedic Surgery
Jun 2005 - Aug 2008
Scripps Research Institute
Post-doc / Adjunct Assistant Professor
Arthritis Research

Publications

26Publications

524Reads

1433Profile Views

211PubMed Central Citations

Effects of Micronized Cartilage Matrix on Cartilage Repair in Osteochondral Lesions of the Talus.

Cartilage 2018 Aug 29:1947603518796125. Epub 2018 Aug 29.

1 Department of Orthopaedic Surgery, University of California Davis Medical Center, Sacramento, CA, USA.

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http://dx.doi.org/10.1177/1947603518796125DOI Listing
August 2018
25 Reads

Flavopiridol Protects Bone Tissue by Attenuating RANKL Induced Osteoclast Formation.

Front Pharmacol 2018 3;9:174. Epub 2018 May 3.

Department of Orthopaedic Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

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http://dx.doi.org/10.3389/fphar.2018.00174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944179PMC
May 2018
8 Reads
1 Citation

Binding to COMP Reduces the BMP2 Dose for Spinal Fusion in a Rat Model.

Spine (Phila Pa 1976) 2016 Jul;41(14):E829-36

*Lawrence J. Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California Davis, Davis, CA †Department of Biomedical Engineering, University of California Davis, Davis, CA ‡J.D. Wheat Veterinary Orthopaedic Laboratory, School of Veterinary Medicine, University of California Davis, One Shields Avenue, Davis, CA.

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http://dx.doi.org/10.1097/BRS.0000000000001408DOI Listing
July 2016
183 Reads
1 Citation
2.300 Impact Factor

In-vitro and in-vivo imaging of MMP activity in cartilage and joint injury.

Biochem Biophys Res Commun 2015 May 26;460(3):741-6. Epub 2015 Mar 26.

Lawrence J. Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California Davis Medical Center, 4635 Second Avenue Suite 2000, Sacramento CA 95817, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.03.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426085PMC
May 2015
16 Reads
4 Citations
2.300 Impact Factor

Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice.

Arthritis Res Ther 2015 Feb 16;17:30. Epub 2015 Feb 16.

Department of Orthopaedic Surgery, University of California-Davis Medical Center, 4635 2nd Ave, Suite 2000, Sacramento, CA, 95817, USA.

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http://dx.doi.org/10.1186/s13075-015-0546-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355375PMC
February 2015
14 Reads
11 Citations
3.753 Impact Factor

Reply: To PMID 24470357.

Arthritis Rheumatol 2014 Dec;66(12):3526

University of California, Davis, Sacramento, CA.

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http://dx.doi.org/10.1002/art.38817DOI Listing
December 2014
13 Reads

Cartilage oligomeric matrix protein and its binding partners in the cartilage extracellular matrix: interaction, regulation and role in chondrogenesis.

Matrix Biol 2014 Jul 2;37:102-11. Epub 2014 Jul 2.

Department of Orthopaedic Surgery, Lawrence J. Ellison Musculoskeletal Research Center, University of California at Davis Medical Center, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.1016/j.matbio.2014.06.001DOI Listing
July 2014
17 Reads
20 Citations
5.074 Impact Factor

Comparison of loading rate-dependent injury modes in a murine model of post-traumatic osteoarthritis.

J Orthop Res 2014 Jan 9;32(1):79-88. Epub 2013 Sep 9.

Department of Orthopaedic Surgery, University of California-Davis Medical Center, 4635 2nd Ave, Suite 2000, Sacramento, California, 95817.

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http://dx.doi.org/10.1002/jor.22480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140447PMC
January 2014
14 Reads
17 Citations
2.990 Impact Factor

The Oncogene LRF Stimulates Proliferation of Mesenchymal Stem Cells and Inhibits Their Chondrogenic Differentiation.

Cartilage 2013 Oct;4(4):329-38

Department of Orthopaedic Surgery, Lawrence J. Ellison Musculoskeletal Research Center, University of California Davis Medical Center, Sacramento, CA, USA.

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http://dx.doi.org/10.1177/1947603513497570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297155PMC
October 2013
14 Reads

Cartilage oligomeric matrix protein enhances osteogenesis by directly binding and activating bone morphogenetic protein-2.

Bone 2013 Jul 23;55(1):23-35. Epub 2013 Mar 23.

Lawrence J. Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California Davis Medical Center, 4635 Second Avenue Suite 2000, Sacramento CA 95817, USA.

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http://dx.doi.org/10.1016/j.bone.2013.03.007DOI Listing
July 2013
13 Reads
7 Citations

c-Maf Transcription Factor Regulates ADAMTS-12 Expression in Human Chondrogenic Cells.

Cartilage 2013 Apr;4(2):177-86

Lawrence J. Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California Davis Medical Center, Sacramento, CA, USA.

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http://dx.doi.org/10.1177/1947603512472697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297105PMC
April 2013
12 Reads
1 Citation

Interactions between FGF21 and BMP-2 in osteogenesis.

Biochem Biophys Res Commun 2013 Mar 14;432(4):677-82. Epub 2013 Feb 14.

Lawrence J.Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California Davis, 4635 Second Avenue, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.1016/j.bbrc.2013.02.019DOI Listing
March 2013
13 Reads
5 Citations
2.300 Impact Factor

The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance.

Carcinogenesis 2012 Nov 30;33(11):2076-83. Epub 2012 Jul 30.

Department of Orthopaedic Surgery, Lawrence J. Ellison Musculoskeletal Research Center, University of California Davis Medical Center, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.1093/carcin/bgs254DOI Listing
November 2012
14 Reads
3 Citations
5.334 Impact Factor

Identification of a 3Kbp mechanoresponsive promoter region in the human cartilage oligomeric matrix protein gene.

Tissue Eng Part A 2012 Sep 10;18(17-18):1882-9. Epub 2012 Aug 10.

Department of Orthopaedic Surgery, University of California, Davis School of Medicine, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.1089/ten.TEA.2011.0497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432897PMC
September 2012
16 Reads
2 Citations

Chondrogenic potential and homogeneity of cell populations of donor and recipient cells in a fresh osteochondral allograft: a case report.

J Bone Joint Surg Am 2012 Feb;94(3):e17

Department of Orthopaedic Surgery, University of California Davis Medical Center, 4860 Y Street, Suite 3800, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.2106/JBJS.J.01969DOI Listing
February 2012
11 Reads
1 Citation
5.280 Impact Factor

Enhanced activity of transforming growth factor β1 (TGF-β1) bound to cartilage oligomeric matrix protein.

J Biol Chem 2011 Dec 22;286(50):43250-8. Epub 2011 Sep 22.

Lawrence J. Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California Davis Medical Center, Sacramento, California 95817, USA.

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http://dx.doi.org/10.1074/jbc.M111.234716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234822PMC
December 2011
15 Reads
11 Citations
4.573 Impact Factor

Vimentin contributes to changes in chondrocyte stiffness in osteoarthritis.

J Orthop Res 2011 Jan;29(1):20-5

Shiley Center for Orthopaedic Research and Education at Scripps Clinic, 11025 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1002/jor.21198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976780PMC
January 2011
14 Reads
22 Citations
2.990 Impact Factor

Role of c-Maf in Chondrocyte Differentiation: A Review.

Cartilage 2011 Jan;2(1):27-35

University of California Davis Medical Center, Division of Orthopaedic Research, Department of Orthopaedic Surgery, Sacramento, CA, USA.

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http://dx.doi.org/10.1177/1947603510377464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300789PMC
January 2011
17 Reads
2 Citations

Rho kinase-dependent activation of SOX9 in chondrocytes.

Arthritis Rheum 2010 Jan;62(1):191-200

The Scripps Research Institute, La Jolla, California, USA.

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http://dx.doi.org/10.1002/art.25051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935318PMC
January 2010
13 Reads
24 Citations
7.764 Impact Factor

Characterization of the chondrocyte actin cytoskeleton in living three-dimensional culture: response to anabolic and catabolic stimuli.

Mol Cell Biomech 2009 Sep;6(3):135-44

Division of Arthritis Research, Department of Molecular and Experimental Medicine, The Scripps Research Institute 10550 North Torrey Pines Road, La Jolla CA 92037, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785729PMC
September 2009
11 Reads
10 Citations

Rho kinase-dependent CCL20 induced by dynamic compression of human chondrocytes.

Arthritis Rheum 2008 Sep;58(9):2735-42

Scripps Research Institute, and Scripps Clinic, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1002/art.23797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562294PMC
September 2008
12 Reads
10 Citations
7.764 Impact Factor

Immunolocalization of IL-17A, IL-17B, and their receptors in chondrocytes during fracture healing.

J Histochem Cytochem 2008 Feb 6;56(2):89-95. Epub 2007 Sep 6.

Center for Tissue Regeneration and Repair, Department of Orthopedics, University of California, School of Medicine, 4635 Second Avenue, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.1369/jhc.7A7223.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324170PMC
February 2008
13 Reads
16 Citations
1.960 Impact Factor

Generation of interleukin-17 receptor-like protein (IL-17RL) in prostate by alternative splicing of RNA.

Prostate 2006 Sep;66(12):1268-74

Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, School of Medicine, University of California, Sacramento, California 95817, USA.

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http://dx.doi.org/10.1002/pros.20422DOI Listing
September 2006
10 Reads
9 Citations
3.565 Impact Factor

Bone morphogenetic protein (BMP)-6 signaling and BMP antagonist noggin in prostate cancer.

Cancer Res 2004 Nov;64(22):8276-84

Center for Tissue Regeneration and Repair, Department of Orthopedic Surgery, School of Medicine, University of California, Davis, Sacramento, California 95817, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-2251DOI Listing
November 2004
10 Reads
24 Citations
9.330 Impact Factor

Top co-authors

Blaine A Christiansen
Blaine A Christiansen

Washington University in St. Louis

4
Eunmee Hong
Eunmee Hong

Lawrence Ellison Center for Tissue Regeneration and Repair

4
Chitrangada Acharya
Chitrangada Acharya

Indian Institute of Technology

4
Martin K Lotz
Martin K Lotz

The Scripps Research Institute

4
Timothy A Moseley
3
Ratna Kumari
Ratna Kumari

Lawrence J. Ellison Musculoskeletal Research Center

3

Followers

Gerrard Rafferty
Gerrard Rafferty

King's College London