Dominik Glodzik

Dominik Glodzik

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Dominik Glodzik

Dominik Glodzik

Publications by authors named "Dominik Glodzik"

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17Publications

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Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study.

Authors:
Johan Staaf Dominik Glodzik Ana Bosch Johan Vallon-Christersson Christel Reuterswärd Jari Häkkinen Andrea Degasperi Tauanne Dias Amarante Lao H Saal Cecilia Hegardt Hilary Stobart Anna Ehinger Christer Larsson Lisa Rydén Niklas Loman Martin Malmberg Anders Kvist Hans Ehrencrona Helen R Davies Åke Borg Serena Nik-Zainal

Nat Med 2019 Oct 30;25(10):1526-1533. Epub 2019 Sep 30.

Academic Department of Medical Genetics, The Clinical School University of Cambridge, Cambridge Biomedical Research Campus, Cambridge, UK.

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http://dx.doi.org/10.1038/s41591-019-0582-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859071PMC
October 2019

Genomic landscape and chronological reconstruction of driver events in multiple myeloma.

Authors:
Francesco Maura Niccoló Bolli Nicos Angelopoulos Kevin J Dawson Daniel Leongamornlert Inigo Martincorena Thomas J Mitchell Anthony Fullam Santiago Gonzalez Raphael Szalat Federico Abascal Bernardo Rodriguez-Martin Mehmet Kemal Samur Dominik Glodzik Marco Roncador Mariateresa Fulciniti Yu Tzu Tai Stephane Minvielle Florence Magrangeas Philippe Moreau Paolo Corradini Kenneth C Anderson Jose M C Tubio David C Wedge Moritz Gerstung Hervé Avet-Loiseau Nikhil Munshi Peter J Campbell

Nat Commun 2019 08 23;10(1):3835. Epub 2019 Aug 23.

The Cancer, Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.

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http://dx.doi.org/10.1038/s41467-019-11680-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707220PMC
August 2019

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation.

Authors:
Arie B Brinkman Serena Nik-Zainal Femke Simmer F Germán Rodríguez-González Marcel Smid Ludmil B Alexandrov Adam Butler Sancha Martin Helen Davies Dominik Glodzik Xueqing Zou Manasa Ramakrishna Johan Staaf Markus Ringnér Anieta Sieuwerts Anthony Ferrari Sandro Morganella Thomas Fleischer Vessela Kristensen Marta Gut Marc J van de Vijver Anne-Lise Børresen-Dale Andrea L Richardson Gilles Thomas Ivo G Gut John W M Martens John A Foekens Michael R Stratton Hendrik G Stunnenberg

Nat Commun 2019 04 15;10(1):1749. Epub 2019 Apr 15.

Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, PO Box 9101, Nijmegen, 6500 HB, The Netherlands.

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http://dx.doi.org/10.1038/s41467-019-09828-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465362PMC
April 2019

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Authors:
Serena Nik-Zainal Helen Davies Johan Staaf Manasa Ramakrishna Dominik Glodzik Xueqing Zou Inigo Martincorena Ludmil B Alexandrov Sancha Martin David C Wedge Peter Van Loo Young Seok Ju Marcel Smid Arie B Brinkman Sandro Morganella Miriam R Aure Ole Christian Lingjærde Anita Langerød Markus Ringnér Sung-Min Ahn Sandrine Boyault Jane E Brock Annegien Broeks Adam Butler Christine Desmedt Luc Dirix Serge Dronov Aquila Fatima John A Foekens Moritz Gerstung Gerrit K J Hooijer Se Jin Jang David R Jones Hyung-Yong Kim Tari A King Savitri Krishnamurthy Hee Jin Lee Jeong-Yeon Lee Yilong Li Stuart McLaren Andrew Menzies Ville Mustonen Sarah O'Meara Iris Pauporté Xavier Pivot Colin A Purdie Keiran Raine Kamna Ramakrishnan F Germán Rodríguez-González Gilles Romieu Anieta M Sieuwerts Peter T Simpson Rebecca Shepherd Lucy Stebbings Olafur A Stefansson Jon Teague Stefania Tommasi Isabelle Treilleux Gert G Van den Eynden Peter Vermeulen Anne Vincent-Salomon Lucy Yates Carlos Caldas Laura Van't Veer Andrew Tutt Stian Knappskog Benita Kiat Tee Tan Jos Jonkers Åke Borg Naoto T Ueno Christos Sotiriou Alain Viari P Andrew Futreal Peter J Campbell Paul N Span Steven Van Laere Sunil R Lakhani Jorunn E Eyfjord Alastair M Thompson Ewan Birney Hendrik G Stunnenberg Marc J van de Vijver John W M Martens Anne-Lise Børresen-Dale Andrea L Richardson Gu Kong Gilles Thomas Michael R Stratton

Nature 2019 02;566(7742):E1

Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.

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http://www.nature.com/articles/s41586-019-0883-2
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http://dx.doi.org/10.1038/s41586-019-0883-2DOI Listing
February 2019

Short inverted repeats contribute to localized mutability in human somatic cells.

Authors:
Xueqing Zou Sandro Morganella Dominik Glodzik Helen Davies Yilin Li Michael R Stratton Serena Nik-Zainal

Nucleic Acids Res 2017 Nov;45(19):11213-11221

Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1093/nar/gkx731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737083PMC
November 2017

Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers.

Authors:
Dominik Glodzik Sandro Morganella Helen Davies Peter T Simpson Yilong Li Xueqing Zou Javier Diez-Perez Johan Staaf Ludmil B Alexandrov Marcel Smid Arie B Brinkman Inga Hansine Rye Hege Russnes Keiran Raine Colin A Purdie Sunil R Lakhani Alastair M Thompson Ewan Birney Hendrik G Stunnenberg Marc J van de Vijver John W M Martens Anne-Lise Børresen-Dale Andrea L Richardson Gu Kong Alain Viari Douglas Easton Gerard Evan Peter J Campbell Michael R Stratton Serena Nik-Zainal

Nat Genet 2017 10;49(11):1661

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http://dx.doi.org/10.1038/ng1117-1661aDOI Listing
October 2017

Whole-Genome Sequencing Reveals Breast Cancers with Mismatch Repair Deficiency.

Authors:
Helen Davies Sandro Morganella Colin A Purdie Se Jin Jang Elin Borgen Hege Russnes Dominik Glodzik Xueqing Zou Alain Viari Andrea L Richardson Anne-Lise Børresen-Dale Alastair Thompson Jorunn E Eyfjord Gu Kong Michael R Stratton Serena Nik-Zainal

Cancer Res 2017 09;77(18):4755-4762

Wellcome Trust Sanger Institute, Hinxton, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-1083DOI Listing
September 2017

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.

Authors:
Helen Davies Dominik Glodzik Sandro Morganella Lucy R Yates Johan Staaf Xueqing Zou Manasa Ramakrishna Sancha Martin Sandrine Boyault Anieta M Sieuwerts Peter T Simpson Tari A King Keiran Raine Jorunn E Eyfjord Gu Kong Åke Borg Ewan Birney Hendrik G Stunnenberg Marc J van de Vijver Anne-Lise Børresen-Dale John W M Martens Paul N Span Sunil R Lakhani Anne Vincent-Salomon Christos Sotiriou Andrew Tutt Alastair M Thompson Steven Van Laere Andrea L Richardson Alain Viari Peter J Campbell Michael R Stratton Serena Nik-Zainal

Nat Med 2017 Apr 13;23(4):517-525. Epub 2017 Mar 13.

Wellcome Trust Sanger Institute, Hinxton, UK.

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http://dx.doi.org/10.1038/nm.4292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833945PMC
April 2017

A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers.

Authors:
Dominik Glodzik Sandro Morganella Helen Davies Peter T Simpson Yilong Li Xueqing Zou Javier Diez-Perez Johan Staaf Ludmil B Alexandrov Marcel Smid Arie B Brinkman Inga Hansine Rye Hege Russnes Keiran Raine Colin A Purdie Sunil R Lakhani Alastair M Thompson Ewan Birney Hendrik G Stunnenberg Marc J van de Vijver John W M Martens Anne-Lise Børresen-Dale Andrea L Richardson Gu Kong Alain Viari Douglas Easton Gerard Evan Peter J Campbell Michael R Stratton Serena Nik-Zainal

Nat Genet 2017 Mar 23;49(3):341-348. Epub 2017 Jan 23.

Wellcome Trust Sanger Institute, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.3771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988034PMC
March 2017

Whole-exome sequencing in an isolated population from the Dalmatian island of Vis.

Authors:
Ana Jeroncic Yasin Memari Graham Rs Ritchie Audrey E Hendricks Anja Kolb-Kokocinski Angela Matchan Veronique Vitart Caroline Hayward Ivana Kolcic Dominik Glodzik Alan F Wright Igor Rudan Harry Campbell Richard Durbin Ozren Polašek Eleftheria Zeggini Vesna Boraska Perica

Eur J Hum Genet 2016 10 6;24(10):1479-87. Epub 2016 Apr 6.

Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1038/ejhg.2016.23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950961PMC
October 2016

Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Authors:
Serena Nik-Zainal Helen Davies Johan Staaf Manasa Ramakrishna Dominik Glodzik Xueqing Zou Inigo Martincorena Ludmil B Alexandrov Sancha Martin David C Wedge Peter Van Loo Young Seok Ju Marcel Smid Arie B Brinkman Sandro Morganella Miriam R Aure Ole Christian Lingjærde Anita Langerød Markus Ringnér Sung-Min Ahn Sandrine Boyault Jane E Brock Annegien Broeks Adam Butler Christine Desmedt Luc Dirix Serge Dronov Aquila Fatima John A Foekens Moritz Gerstung Gerrit K J Hooijer Se Jin Jang David R Jones Hyung-Yong Kim Tari A King Savitri Krishnamurthy Hee Jin Lee Jeong-Yeon Lee Yilong Li Stuart McLaren Andrew Menzies Ville Mustonen Sarah O'Meara Iris Pauporté Xavier Pivot Colin A Purdie Keiran Raine Kamna Ramakrishnan F Germán Rodríguez-González Gilles Romieu Anieta M Sieuwerts Peter T Simpson Rebecca Shepherd Lucy Stebbings Olafur A Stefansson Jon Teague Stefania Tommasi Isabelle Treilleux Gert G Van den Eynden Peter Vermeulen Anne Vincent-Salomon Lucy Yates Carlos Caldas Laura van't Veer Andrew Tutt Stian Knappskog Benita Kiat Tee Tan Jos Jonkers Åke Borg Naoto T Ueno Christos Sotiriou Alain Viari P Andrew Futreal Peter J Campbell Paul N Span Steven Van Laere Sunil R Lakhani Jorunn E Eyfjord Alastair M Thompson Ewan Birney Hendrik G Stunnenberg Marc J van de Vijver John W M Martens Anne-Lise Børresen-Dale Andrea L Richardson Gu Kong Gilles Thomas Michael R Stratton

Nature 2016 06 2;534(7605):47-54. Epub 2016 May 2.

Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature17676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910866PMC
June 2016

The topography of mutational processes in breast cancer genomes.

Authors:
Sandro Morganella Ludmil B Alexandrov Dominik Glodzik Xueqing Zou Helen Davies Johan Staaf Anieta M Sieuwerts Arie B Brinkman Sancha Martin Manasa Ramakrishna Adam Butler Hyung-Yong Kim Åke Borg Christos Sotiriou P Andrew Futreal Peter J Campbell Paul N Span Steven Van Laere Sunil R Lakhani Jorunn E Eyfjord Alastair M Thompson Hendrik G Stunnenberg Marc J van de Vijver John W M Martens Anne-Lise Børresen-Dale Andrea L Richardson Gu Kong Gilles Thomas Julian Sale Cristina Rada Michael R Stratton Ewan Birney Serena Nik-Zainal

Nat Commun 2016 May 2;7:11383. Epub 2016 May 2.

Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1038/ncomms11383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001788PMC
May 2016

The genome as a record of environmental exposure.

Authors:
Serena Nik-Zainal Jill E Kucab Sandro Morganella Dominik Glodzik Ludmil B Alexandrov Volker M Arlt Annette Weninger Monica Hollstein Michael R Stratton David H Phillips

Mutagenesis 2015 Nov 6;30(6):763-70. Epub 2015 Oct 6.

Analytical and Environmental Sciences Division, MRC-PHE Centre for Environment and Health, King's College London, Franklin-Wilkins Building, London SE1 9NH, UK,

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http://dx.doi.org/10.1093/mutage/gev073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637815PMC
November 2015

Plasma vitamin D concentration influences survival outcome after a diagnosis of colorectal cancer.

Authors:
Lina Zgaga Evropi Theodoratou Susan M Farrington Farhat V N Din Li Yin Ooi Dominik Glodzik Susan Johnston Albert Tenesa Harry Campbell Malcolm G Dunlop

J Clin Oncol 2014 Aug 7;32(23):2430-9. Epub 2014 Jul 7.

Lina Zgaga, Susan M. Farrington, Farhat V.N. Din, Li Yin Ooi, Dominik Glodzik, Albert Tenesa, Harry Campbell, and Malcolm G. Dunlop, University of Edinburgh and Western General Hospital; Evropi Theodoratou and Harry Campbell, University of Edinburgh, Edinburgh; Albert Tenesa, University of Edinburgh, Roslin; Susan Johnston, Glasgow Royal Infirmary, Glasgow, United Kingdom; Lina Zgaga, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1200/JCO.2013.54.5947DOI Listing
August 2014

Local exome sequences facilitate imputation of less common variants and increase power of genome wide association studies.

Authors:
Peter K Joshi James Prendergast Ross M Fraser Jennifer E Huffman Veronique Vitart Caroline Hayward Ruth McQuillan Dominik Glodzik Ozren Polašek Nicholas D Hastie Igor Rudan Harry Campbell Alan F Wright Chris S Haley James F Wilson Pau Navarro

PLoS One 2013 16;8(7):e68604. Epub 2013 Jul 16.

Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0068604PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712964PMC
February 2014

Inference of identity by descent in population isolates and optimal sequencing studies.

Authors:
Dominik Glodzik Pau Navarro Veronique Vitart Caroline Hayward Ruth McQuillan Sarah H Wild Malcolm G Dunlop Igor Rudan Harry Campbell Chris Haley Alan F Wright James F Wilson Paul McKeigue

Eur J Hum Genet 2013 Oct 30;21(10):1140-5. Epub 2013 Jan 30.

MRC Institute of Genetics and Molecular Medicine (MRC IGMM), MRC Human Genetics Unit, University of Edinburgh, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1038/ejhg.2012.307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778345PMC
October 2013

Utility of non-rule-based visual matching as a strategy to allow novices to achieve skin lesion diagnosis.

Authors:
R Benjamin Aldridge Dominik Glodzik Lucia Ballerini Robert B Fisher Jonathan L Rees

Acta Derm Venereol 2011 May;91(3):279-83

Department of Dermatology, University of Edinburgh, Scotland.

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http://dx.doi.org/10.2340/00015555-1049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160473PMC
May 2011