Publications by authors named "Dominik Feuerbach"

58 Publications

Alkaloids Purified from Inhibit the Human α3β4 Nicotinic Acetylcholine Receptor with Higher Potencies Compared with the Human α4β2 and α7 Subtypes.

J Nat Prod 2019 07 5;82(7):1953-1960. Epub 2019 Jul 5.

Laboratory of Natural Products and Drug Discovery, Department of Basic Sciences , Universidad de La Frontera , 4780000 Temuco , Chile.

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July 2019

The Discovery of LML134, a Histamine H3 Receptor Inverse Agonist for the Clinical Treatment of Excessive Sleep Disorders.

ChemMedChem 2019 07 21;14(13):1238-1247. Epub 2019 May 21.

Novartis Institutes for BioMedical Research, Novartis Pharma AG, Klybeckstrasse 141, 4057, Basel, Switzerland.

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July 2019

Tricyclic antidepressants inhibit hippocampal α7* and α9α10 nicotinic acetylcholine receptors by different mechanisms.

Int J Biochem Cell Biol 2018 07 25;100:1-10. Epub 2018 Apr 25.

Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, Mexico.

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July 2018

Microglia M2A Polarization as Potential Link between Food Allergy and Autism Spectrum Disorders.

Pharmaceuticals (Basel) 2017 Dec 9;10(4). Epub 2017 Dec 9.

Novartis Pharma AG, CH4002 Basel, Switzerland.

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December 2017

Selectivity of coronaridine congeners at nicotinic acetylcholine receptors and inhibitory activity on mouse medial habenula.

Int J Biochem Cell Biol 2017 11 16;92:202-209. Epub 2017 Oct 16.

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

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November 2017

Task-related fMRI responses to a nicotinic acetylcholine receptor partial agonist in schizophrenia: A randomized trial.

Prog Neuropsychopharmacol Biol Psychiatry 2016 11 28;71:66-75. Epub 2016 Jun 28.

Novartis Pharma AG, Basel, Switzerland; Department of Neurology and Neurosurgery, McGill University, Montreal, Québec, Canada. Electronic address:

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November 2016

Antidepressant therapies inhibit inflammation and microglial M1-polarization.

Pharmacol Ther 2016 07 18;163:82-93. Epub 2016 Apr 18.

Neuroscience Research, NIBR, Fabrikstrasse 22-3.001.02, Basel 4002, Switzerland.

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July 2016

Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders.

Cell Mol Life Sci 2016 Jul 15;73(13):2511-30. Epub 2016 Mar 15.

Neuroscience Research, NIBR, Fabrikstrasse 22-3.001.02, 4002, Basel, Switzerland.

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July 2016

Exploring the positive allosteric modulation of human α7 nicotinic receptors from a single-channel perspective.

Neuropharmacology 2016 08 27;107:189-200. Epub 2016 Feb 27.

Universidad Nacional del Sur/CONICET, Instituto de Investigaciones Bioquímicas de Bahía Blanca, Bahía Blanca 8000, Argentina. Electronic address:

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August 2016

The antidepressant-like activity of nicotine, but not of 3-furan-2-yl-N-p-tolyl-acrylamide, is regulated by the nicotinic receptor β4 subunit.

Neurochem Int 2015 Aug 23;87:110-6. Epub 2015 Jun 23.

Department of Chemistry, Laboratory of Medicinal Chemistry and Neuroengineering, Medical University of Lublin, Lublin, Poland.

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August 2015

Coronaridine congeners inhibit human α3β4 nicotinic acetylcholine receptors by interacting with luminal and non-luminal sites.

Int J Biochem Cell Biol 2015 Aug 27;65:81-90. Epub 2015 May 27.

Department of Chemistry, Medical University of Lublin, Lublin, Poland.

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August 2015

Functional and structural interaction of (-)-lobeline with human α4β2 and α4β4 nicotinic acetylcholine receptor subtypes.

Int J Biochem Cell Biol 2015 Jul 18;64:15-24. Epub 2015 Mar 18.

Faculty of Medicine and CONICET, University of Morón, Argentina.

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July 2015

AQW051, a novel and selective nicotinic acetylcholine receptor α7 partial agonist, reduces l-Dopa-induced dyskinesias and extends the duration of l-Dopa effects in parkinsonian monkeys.

Parkinsonism Relat Disord 2014 Nov 22;20(11):1119-23. Epub 2014 May 22.

Novartis Institutes for BioMedical Research Basel, Basel, Switzerland; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, QC, Canada. Electronic address:

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November 2014

Bupropion-induced inhibition of α7 nicotinic acetylcholine receptors expressed in heterologous cells and neurons from dorsal raphe nucleus and hippocampus.

Eur J Pharmacol 2014 Oct 9;740:103-11. Epub 2014 Jul 9.

Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla 3001, Querétaro 76230, México. Electronic address:

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October 2014

Antidepressant activity in mice elicited by 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic acetylcholine receptor.

Neurosci Lett 2014 May 5;569:126-30. Epub 2014 Apr 5.

Department of Medical Education, California Northstate University College of Medicine, 9700 West Taron Drive, Elk Grove, CA 95757, USA. Electronic address:

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May 2014

Differential pharmacological activity of JN403 between α7 and muscle nicotinic acetylcholine receptors.

Biochemistry 2013 Nov 11;52(47):8480-8. Epub 2013 Nov 11.

Department of Medical Education, California Northstate University College of Medicine , Elk Grove, California 95757, United States.

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November 2013

Novel 2-(substituted benzyl)quinuclidines inhibit human α7 and α4β2 nicotinic receptors by different mechanisms.

Int J Biochem Cell Biol 2013 Nov 14;45(11):2420-30. Epub 2013 Aug 14.

Department of Medical Education, California Northstate University College of Medicine, Elk Grove, CA 95757, USA. Electronic address:

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November 2013

(-)-Reboxetine inhibits muscle nicotinic acetylcholine receptors by interacting with luminal and non-luminal sites.

Neurochem Int 2013 Nov 31;63(5):423-31. Epub 2013 Jul 31.

Department of Medical Education, California Northstate University College of Medicine, Elk Grove, CA, USA. Electronic address:

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November 2013