Dolores Isla

Dolores Isla

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Dolores Isla

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Oral vinorelbine versus etoposide with cisplatin and chemo-radiation as treatment in patients with stage III non-small cell lung cancer: A randomized phase II (RENO study).

Authors:
Dolores Isla Ramón De Las Peñas Amelia Insa Raquel Marsé Natividad Martínez-Banaclocha Pilar Mut Teresa Morán María Ángeles Sala Bartomeu Massuti Ana Laura Ortega José Miguel Jurado José Gómez-Codina Pilar Diz Ángel Artal Vanesa Gutiérrez María Francisca Vázquez Nuria Viñolas Inmaculada Maestu Carlos Camps Rosa Álvarez Melchor Álvarez de Mon Soto Santiago Ponce Mariano Provencio

Lung Cancer 2019 Sep 1;135:161-168. Epub 2018 Dec 1.

Medical Oncology, University Hospital Puerta de Hierro, Majadahonda Medical Oncology. Spanish Lung Cancer Group (SLCG), Spain. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.11.041DOI Listing
September 2019

Clinical utility of plasma-based digital next-generation sequencing in oncogene-driven non-small-cell lung cancer patients with tyrosine kinase inhibitor resistance.

Authors:
Jon Zugazagoitia Ana Gómez-Rueda Eloisa Jantus-Lewintre Dolores Isla Carlos Camps Inmaculada Ramos Jose Manuel Trigo Reyes Bernabé Oscar Juan-Vidal Jose Miguel Sanchez-Torres Rosario García-Campelo Mariano Provencio Enriqueta Felip Javier de Castro Iris Faull Richard B Lanman Santiago Ponce-Aix Luis Paz-Ares Pilar Garrido

Lung Cancer 2019 Aug 30;134:72-78. Epub 2019 May 30.

CIBERONC, Spain; Medical Oncology Department, IRYCIS Hospital Universitario Ramón y Cajal, Universidad Alcalá, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.05.032DOI Listing
August 2019

Thermal Liquid Biopsy (TLB): A Predictive Score Derived from Serum Thermograms as a Clinical Tool for Screening Lung Cancer Patients.

Authors:
Alberto Rodrigo Jorge L Ojeda Sonia Vega Oscar Sanchez-Gracia Angel Lanas Dolores Isla Adrian Velazquez-Campoy Olga Abian

Cancers (Basel) 2019 Jul 19;11(7). Epub 2019 Jul 19.

Institute of Biocomputation and Physics of Complex Systems (BIFI), Joint Units IQFR-CSIC-BIFI, and GBsC-CSIC-BIFI, Universidad de Zaragoza, 50018 Zaragoza, Spain.

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http://dx.doi.org/10.3390/cancers11071012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678750PMC
July 2019

Afatinib With Pembrolizumab for Treatment of Patients With Locally Advanced/Metastatic Squamous Cell Carcinoma of the Lung: The LUX-Lung IO/KEYNOTE 497 Study Protocol.

Authors:
Benjamin Levy Luis Paz-Ares Jaafar Bennouna Enriqueta Felip Delvys Rodríguez Abreu Dolores Isla Fabrice Barlesi Olivier Molinier Jeannick Madelaine Clarisse Audigier-Valette Sang-We Kim Hye Ryun Kim Mustafa Ozguroglu Mustafa Erman Firas Benyamine Badin Tarek M Mekhail Ronald Scheff Michael J Chisamore Behbood Sadrolhefazi Jonathan W Riess

Clin Lung Cancer 2019 05 4;20(3):e407-e412. Epub 2019 Jan 4.

UC Davis Comprehensive Cancer Center, Sacramento, CA.

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http://dx.doi.org/10.1016/j.cllc.2018.12.022DOI Listing
May 2019

Trastuzumab Emtansine (T-DM1) in Patients with Previously Treated HER2-Overexpressing Metastatic Non-Small Cell Lung Cancer: Efficacy, Safety, and Biomarkers.

Authors:
Solange Peters Rolf Stahel Lukas Bubendorf Philip Bonomi Augusto Villegas Dariusz M Kowalski Christina S Baik Dolores Isla Javier De Castro Carpeno Pilar Garrido Achim Rittmeyer Marcello Tiseo Christoph Meyenberg Sanne de Haas Lisa H Lam Michael W Lu Thomas E Stinchcombe

Clin Cancer Res 2019 01 11;25(1):64-72. Epub 2018 Sep 11.

Duke Cancer Institute, Duke University School of Medicine, Durham, North Carolina.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-18-1590DOI Listing
January 2019

Lung cancer in Spanish women: The WORLD07 project.

Authors:
Pilar Garrido Nuria Viñolas Dolores Isla Mariano Provencio Margarita Majem Angel Artal Enric Carcereny Rosario Garcia Campelo Pilar Lianes Ramon De La Peñas Enriqueta Felip

Eur J Cancer Care (Engl) 2019 Jan 2;28(1):e12941. Epub 2018 Oct 2.

Hospital Vall Hebron, Barcelona, Spain.

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http://doi.wiley.com/10.1111/ecc.12941
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http://dx.doi.org/10.1111/ecc.12941DOI Listing
January 2019

Association of ERBB Mutations With Clinical Outcomes of Afatinib- or Erlotinib-Treated Patients With Lung Squamous Cell Carcinoma: Secondary Analysis of the LUX-Lung 8 Randomized Clinical Trial.

Authors:
Glenwood D Goss Enriqueta Felip Manuel Cobo Shun Lu Konstantinos Syrigos Ki Hyeong Lee Erdem Göker Vassilis Georgoulias Wei Li Salih Guclu Dolores Isla Young Joo Min Alessandro Morabito Andrea Ardizzoni Shirish M Gadgeel Andrea Fülöp Claudia Bühnemann Neil Gibson Nicole Krämer Flavio Solca Agnieszka Cseh Eva Ehrnrooth Jean-Charles Soria

JAMA Oncol 2018 09;4(9):1189-1197

Department of Medical Oncology, Gustave Roussy Cancer Campus and University Paris-Sud, Paris, France.

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http://dx.doi.org/10.1001/jamaoncol.2018.0775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143014PMC
September 2018

Clinical management and outcome of patients with advanced NSCLC carrying EGFR mutations in Spain.

Authors:
Edurne Arriola Ramón García Gómez Pilar Diz Margarita Majem Maite Martínez Aguillo Javier Valdivia Alfredo Paredes José Miguel Sánchez-Torres Sergio Peralta Muñoz Isidoro Barneto Vanesa Gutierrez Jesús Manuel Andrade Santiago Francisco Aparisi Dolores Isla Santiago Ponce David Vicente Baz Angel Artal Mariluz Amador Mariano Provencio

BMC Cancer 2018 01 30;18(1):106. Epub 2018 Jan 30.

Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1186/s12885-018-4004-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791371PMC
January 2018

Reflections on the Implementation of Low-Dose Computed Tomography Screening in Individuals at High Risk of Lung Cancer in Spain.

Authors:
Pilar Garrido Marcelo Sánchez José Belda Sanchis Nicolás Moreno Mata Ángel Artal Ángel Gayete José María Matilla González José Marcelo Galbis Caravajal Dolores Isla Luis Paz-Ares Luis M Seijo

Arch Bronconeumol 2017 Oct 14;53(10):568-573. Epub 2017 Apr 14.

Servicio de Neumología, Hospital Universitario Fundación Jiménez Díaz, Instituto de Investigación Sanitaria, CIBERES, Madrid, España.

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http://dx.doi.org/10.1016/j.arbres.2017.03.004DOI Listing
October 2017

-paclitaxel/carboplatin induction in squamous NSCLC: longitudinal quality of life while on chemotherapy.

Authors:
Michael Thomas David R Spigel Robert M Jotte Michael McCleod Mark A Socinski Ray D Page Laurent Gressot Jeanna Knoble Oscar Juan Daniel Morgensztern Dolores Isla Edward S Kim Howard West Amy Ko Teng Jin Ong Nataliya Trunova Cesare Gridelli

Lung Cancer (Auckl) 2017 30;8:207-216. Epub 2017 Oct 30.

Department of Oncology/Hematology, S.G. Moscati Hospital, Avellino, Italy.

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http://dx.doi.org/10.2147/LCTT.S138570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679693PMC
October 2017

Evaluation of the VeriStrat serum protein test in patients with advanced squamous cell carcinoma of the lung treated with second-line afatinib or erlotinib in the phase III LUX-Lung 8 study.

Authors:
Shirish Gadgeel Glenwood Goss Jean-Charles Soria Enriqueta Felip Vassilis Georgoulias Shun Lu Manuel Cobo Konstantinos Syrigos Ki Hyeong Lee Erdem Göker Salih Z Guclu Dolores Isla Alessandro Morabito Nicholas Dupuis Claudia Bühnemann Nicole Krämer Flavio Solca Eva Ehrnrooth Andrea Ardizzoni

Lung Cancer 2017 07 11;109:101-108. Epub 2017 May 11.

University Hospital, Via Albertoni 15, 40138 Bologna, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.05.010DOI Listing
July 2017

A phase Ib trial of continuous once-daily oral afatinib plus sirolimus in patients with epidermal growth factor receptor mutation-positive non-small cell lung cancer and/or disease progression following prior erlotinib or gefitinib.

Authors:
Teresa Moran Ramón Palmero Mariano Provencio Amelia Insa Margarita Majem Noemí Reguart Joaquim Bosch-Barrera Dolores Isla Enric Carcereny Costa Chooi Lee Marta Puig Sandrine Kraemer David Schnell Rafael Rosell

Lung Cancer 2017 06 22;108:154-160. Epub 2017 Mar 22.

Cancer Biology & Precision Medicine Program, Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Spain; Dr. Rosell Oncology Institute, Quirón Dexeus University Hospital, Barcelona, Spain; Molecular Oncology Research Foundation (MORe), Barcelona, Spain; Universitat Autònoma de Barcelona (UAB) Campus Can Ruti, Carretera de Canyet s/n, 08916 Badalona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.03.009DOI Listing
June 2017

Lung Cancer in Never-Smoking Women: A Sub-Analysis of the Spanish Female-Specific Database WORLD07.

Authors:
Nuria Viñolas Pilar Garrido Dolores Isla Mariano Provencio Margarita Majem Angel Artal Enric Carcereny Rosario Garcia Campelo Pilar Lianes Ramon De La Peñas Enriqueta Felip

Cancer Invest 2017 May 28;35(5):358-365. Epub 2017 Mar 28.

k Hospital Vall d'Hebron , Barcelona , Spain.

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http://dx.doi.org/10.1080/07357907.2017.1295461DOI Listing
May 2017

Equity, barriers and cancer disparities: study of the Spanish Society of Medical Oncology on the access to oncologic drugs in the Spanish Regions.

Authors:
Javier Salvador Jorge Aparicio Francisco Javier Baron Rosario Garcia-Campelo Rocio Garcia-Carbonero Pilar Lianes Antonio Llombart Dolores Isla Josep Manuel Piera Montserrat Munoz Javier Puente Fernando Rivera Cesar A Rodriguez Juan Antonio Virizuela Miguel Martin Pilar Garrido

Clin Transl Oncol 2017 03 25;19(3):341-356. Epub 2016 Aug 25.

Medical Oncology Department, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

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http://dx.doi.org/10.1007/s12094-016-1535-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306184PMC
March 2017

Correlation of DNA Repair Gene Polymorphisms With Clinical Outcome in Patients With Locally Advanced Non-Small-Cell Lung Cancer Receiving Induction Chemotherapy Followed by Surgery.

Authors:
Mariacarmela Santarpia Jose Luis Ramirez Itziar de Aguirre Pilar Garrido Maria Pérez Cano Cristina Queralt Jose Luis Gonzalez-Larriba Amelia Insa Mariano Provencio Dolores Isla Carlos Camps Remei Blanco Teresa Moran Rafael Rosell

Clin Lung Cancer 2017 03 9;18(2):178-188.e4. Epub 2016 Nov 9.

Cancer Biology and Precision Medicine Program, Hospital Germans Trias i Pujol, Catalan Institute of Oncology, Badalona, Spain; Dr Rosell Oncology Institute, Quirón Dexeus University Hospital, Barcelona, Spain; Germans Trias i Pujol Health Sciences Institute and Hospital, Campus Can Ruti, Badalona, Spain.

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http://dx.doi.org/10.1016/j.cllc.2016.08.007DOI Listing
March 2017

Efficacy and Safety Results From a Phase II, Placebo-Controlled Study of Onartuzumab Plus First-Line Platinum-Doublet Chemotherapy for Advanced Squamous Cell Non-Small-Cell Lung Cancer.

Authors:
Fred R Hirsch Ramaswamy Govindan Zanete Zvirbule Fadi Braiteh Achim Rittmeyer Cristóbal Belda-Iniesta Dolores Isla Thomas Cosgriff Michelle Boyer Masamichi Ueda See Phan David R Gandara

Clin Lung Cancer 2017 01 4;18(1):43-49. Epub 2016 Jun 4.

Division of Hematology-Oncology, University of California Davis Cancer Center, Sacramento, CA.

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http://dx.doi.org/10.1016/j.cllc.2016.05.011DOI Listing
January 2017

Lung Cancer in Women with a Family History of Cancer: The Spanish Female-specific Database WORLD07.

Authors:
Dolores Isla Enriqueta Felip Nuria Viñolas Mariano Provencio Margarita Majem Angel Artal Isabel Bover Pilar Lianes Ramón DE Las Peñas Silvia Catot Javier DE Castro Ana Blasco Josefa Terrasa José Luis Gonzalez-Larriba Oscar Juan Manuel Dómine Reyes Bernabe Pilar Garrido

Anticancer Res 2016 12;36(12):6647-6653

Medical Oncology Department, Hospital Ramón y Cajal, Madrid, Spain.

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http://dx.doi.org/10.21873/anticanres.11273DOI Listing
December 2016

Costs of adverse events associated with erlotinib or afatinib in first-line treatment of advanced EGFR-positive non-small cell lung cancer.

Authors:
Dolores Isla Javier De Castro Oscar Juan Santiago Grau Javier Orofino Rocío Gordo Carlos Rubio-Terrés Darío Rubio-Rodríguez

Clinicoecon Outcomes Res 2017 30;9:31-38. Epub 2016 Dec 30.

Health Value, Health Economics, Madrid, Spain.

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http://dx.doi.org/10.2147/CEOR.S121093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221482PMC
December 2016

Therapeutic Potential of Denosumab in Patients With Lung Cancer: Beyond Prevention of Skeletal Complications.

Authors:
Javier De Castro Rosario García Pilar Garrido Dolores Isla Bartomeu Massuti Belén Blanca Jimena Vázquez

Clin Lung Cancer 2015 Nov 25;16(6):431-46. Epub 2015 Jun 25.

Amgen S.A., Barcelona, Spain.

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http://dx.doi.org/10.1016/j.cllc.2015.06.004DOI Listing
November 2015

Afatinib versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung (LUX-Lung 8): an open-label randomised controlled phase 3 trial.

Authors:
Jean-Charles Soria Enriqueta Felip Manuel Cobo Shun Lu Konstantinos Syrigos Ki Hyeong Lee Erdem Göker Vassilis Georgoulias Wei Li Dolores Isla Salih Z Guclu Alessandro Morabito Young J Min Andrea Ardizzoni Shirish M Gadgeel Bushi Wang Vikram K Chand Glenwood D Goss

Lancet Oncol 2015 Aug 5;16(8):897-907. Epub 2015 Jul 5.

Division of Medical Oncology, University of Ottawa, Ottawa, ON, Canada.

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http://dx.doi.org/10.1016/S1470-2045(15)00006-6DOI Listing
August 2015

Association of EGFR L858R Mutation in Circulating Free DNA With Survival in the EURTAC Trial.

Authors:
Niki Karachaliou Clara Mayo-de las Casas Cristina Queralt Itziar de Aguirre Boris Melloni Felipe Cardenal Ramon Garcia-Gomez Bartomeu Massuti José Miguel Sánchez Ruth Porta Santiago Ponce-Aix Teresa Moran Enric Carcereny Enriqueta Felip Isabel Bover Amelia Insa Noemí Reguart Dolores Isla Alain Vergnenegre Filippo de Marinis Radj Gervais Romain Corre Luis Paz-Ares Daniela Morales-Espinosa Santiago Viteri Ana Drozdowskyj Núria Jordana-Ariza Jose Luis Ramirez-Serrano Miguel Angel Molina-Vila Rafael Rosell

JAMA Oncol 2015 May;1(2):149-57

Instituto Oncológico Dr Rosell, Quiron-Dexeus University Hospital, Barcelona, Spain3Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain22MORe Foundation, Barcelona, Spain23Cancer Therapeutic Innovation Group, New York, New York.

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http://dx.doi.org/10.1001/jamaoncol.2014.257DOI Listing
May 2015

Phase I/II trial of vorinostat (SAHA) and erlotinib for non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations after erlotinib progression.

Authors:
Noemi Reguart Rafael Rosell Felipe Cardenal Andres F Cardona Dolores Isla Ramon Palmero Teresa Moran Christian Rolfo M Cinta Pallarès Amelia Insa Enric Carcereny Margarita Majem Javier De Castro Cristina Queralt Miguel A Molina Miquel Taron

Lung Cancer 2014 May 2;84(2):161-7. Epub 2014 Mar 2.

Medical Oncology Department, Hospital Germans Trías i Pujol, Institut Català d'Oncologia-ICO, Badalona, Barcelona, Spain; Pangaea Biotech, Hospital Universitario Quirón, Dexeus, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.lungcan.2014.02.011DOI Listing
May 2014

Randomized phase II trial of non-platinum induction or consolidation chemotherapy plus concomitant chemoradiation in stage III NSCLC patients: mature results of the Spanish Lung Cancer Group 0008 study.

Authors:
Pilar Garrido Rafael Rosell Antonio Arellano Francisco Andreu Manuel Dómine Ana Perez-Casas Felipe Cardenal María Del Mar Arnaiz Teresa Morán Rosa Morera Dolores Isla Javier Valencia Manuel Cobo Raquel Delgado Ramón García-Gómez Felipe Calvo Javier Zamora Alfredo Ramos Bartomeu Massutí

Lung Cancer 2013 Jul 21;81(1):84-90. Epub 2013 Apr 21.

Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Hospital Universitario Ramón y Cajal, Madrid, Spain.

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http://dx.doi.org/10.1016/j.lungcan.2013.03.009DOI Listing
July 2013

Zoledronic acid in lung cancer with bone metastases: a review.

Authors:
Dolores Isla Ruth Afonso Joaquim Bosch-Barrera Natividad Martínez

Expert Rev Anticancer Ther 2013 Apr;13(4):421-6

Servicio de Oncología Médica, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.

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http://dx.doi.org/10.1586/era.13.15DOI Listing
April 2013

Pilot study on workload estimate in breast cancer, lung cancer and colorectal cancer in a Medical Oncology Service at Valme hospital.

Authors:
Javier Salvador Cristina Grávalos Joan Albanell Agustin Barnadas Pablo Borrega Jesús García-Mata Pilar Garrido Encarnación Gonzalez-Flores Dolores Isla María Lomas Alvaro Rodríguez-Lescure Juan Jesus Cruz Emilio Alba

Clin Transl Oncol 2012 Nov 2;14(11):820-6. Epub 2012 Aug 2.

Servicio de Oncología Médica, Avda. Cádiz s/nº, 41014, Sevilla, Spain.

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http://dx.doi.org/10.1007/s12094-012-0873-4DOI Listing
November 2012

Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium.

Authors:
Michele L Coté Mei Liu Stefano Bonassi Monica Neri Ann G Schwartz David C Christiani Margaret R Spitz Joshua E Muscat Gad Rennert Katja K Aben Angeline S Andrew Vladimir Bencko Heike Bickeböller Paolo Boffetta Paul Brennan Hermann Brenner Eric J Duell Eleonora Fabianova John K Field Lenka Foretova Søren Friis Curtis C Harris Ivana Holcatova Yun-Chul Hong Dolores Isla Vladimir Janout Lambertus A Kiemeney Chikako Kiyohara Qing Lan Philip Lazarus Jolanta Lissowska Loic Le Marchand Dana Mates Keitaro Matsuo Jose I Mayordomo John R McLaughlin Hal Morgenstern Heiko Müeller Irene Orlow Bernard J Park Mila Pinchev Olaide Y Raji Hedy S Rennert Peter Rudnai Adeline Seow Isabelle Stucker Neonila Szeszenia-Dabrowska M Dawn Teare Anne Tjønnelan Donatella Ugolini Henricus F M van der Heijden Erich Wichmann John K Wiencke Penella J Woll Ping Yang David Zaridze Zuo-Feng Zhang Carol J Etzel Rayjean J Hung

Eur J Cancer 2012 Sep 19;48(13):1957-68. Epub 2012 Mar 19.

Wayne State University School of Medicine and the Karmanos Cancer Institute, Michigan, USA.

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http://dx.doi.org/10.1016/j.ejca.2012.01.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445438PMC
September 2012

Trabectedin in patients with advanced non-small-cell lung cancer (NSCLC) with XPG and/or ERCC1 overexpression and BRCA1 underexpression and pretreated with platinum.

Authors:
Bartomeu Massuti Manuel Cobo Carlos Camps Manuel Dómine Mariano Provencio Vicente Alberola Nuria Viñolas Rafael Rosell Miguel Tarón Vanesa Gutiérrez-Calderón Pilar Lardelli Vicente Alfaro Antonio Nieto Dolores Isla

Lung Cancer 2012 Jun 23;76(3):354-61. Epub 2011 Dec 23.

Hospital General Universitario de Alicante, Alicante, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S01695002110063
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http://dx.doi.org/10.1016/j.lungcan.2011.12.002DOI Listing
June 2012

MO19390 (SAiL): bleeding events in a phase IV study of first-line bevacizumab with chemotherapy in patients with advanced non-squamous NSCLC.

Authors:
Eric Dansin Saverio Cinieri Pilar Garrido Frank Griesinger Dolores Isla Manfred Koehler Martin Kohlhaeufl

Lung Cancer 2012 Jun 10;76(3):373-9. Epub 2012 Jan 10.

Centre Oscar Lambret, Département de cancérologie générale, Lille Cedex, France.

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http://linkinghub.elsevier.com/retrieve/pii/S016950021100594
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http://dx.doi.org/10.1016/j.lungcan.2011.11.020DOI Listing
June 2012

Functions and workload of medical oncologists in Spain.

Authors:
Cristina Grávalos Javier Salvador Joan Albanell Agustín Barnadas Pablo Borrega Jesús García-Mata Pilar Garrido Encarnación González-Flores Dolores Isla María Lomas Álvaro Rodríguez-Lescure Juan Jesús Cruz Emilio Alba

Clin Transl Oncol 2012 Jun;14(6):423-9

Servicio de Oncología Médica, Hospital Universitario 12 de Octubre, Avda. de Córdoba, s/n - km 5,400, ES-28041 Madrid, Spain.

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http://dx.doi.org/10.1007/s12094-012-0819-xDOI Listing
June 2012

Guidelines for biomarker testing in advanced non-small-cell lung cancer. A national consensus of the Spanish Society of Medical Oncology (SEOM) and the Spanish Society of Pathology (SEAP).

Authors:
Pilar Garrido Javier de Castro Ángel Concha Enriqueta Felip Dolores Isla Fernando López-Ríos Luis Paz-Ares José Ramírez Julián Sanz José Javier Gómez

Clin Transl Oncol 2012 May;14(5):338-49

Medical Oncology Service, Universitary Hospital Ramón y Cajal, Madrid, Spain.

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http://dx.doi.org/10.1007/s12094-012-0806-2DOI Listing
May 2012

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial.

Authors:
Rafael Rosell Enric Carcereny Radj Gervais Alain Vergnenegre Bartomeu Massuti Enriqueta Felip Ramon Palmero Ramon Garcia-Gomez Cinta Pallares Jose Miguel Sanchez Rut Porta Manuel Cobo Pilar Garrido Flavia Longo Teresa Moran Amelia Insa Filippo De Marinis Romain Corre Isabel Bover Alfonso Illiano Eric Dansin Javier de Castro Michele Milella Noemi Reguart Giuseppe Altavilla Ulpiano Jimenez Mariano Provencio Miguel Angel Moreno Josefa Terrasa Jose Muñoz-Langa Javier Valdivia Dolores Isla Manuel Domine Olivier Molinier Julien Mazieres Nathalie Baize Rosario Garcia-Campelo Gilles Robinet Delvys Rodriguez-Abreu Guillermo Lopez-Vivanco Vittorio Gebbia Lioba Ferrera-Delgado Pierre Bombaron Reyes Bernabe Alessandra Bearz Angel Artal Enrico Cortesi Christian Rolfo Maria Sanchez-Ronco Ana Drozdowskyj Cristina Queralt Itziar de Aguirre Jose Luis Ramirez Jose Javier Sanchez Miguel Angel Molina Miquel Taron Luis Paz-Ares

Lancet Oncol 2012 Mar 26;13(3):239-46. Epub 2012 Jan 26.

Catalan Institute of Oncology, Badalona, Spain.

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http://dx.doi.org/10.1016/S1470-2045(11)70393-XDOI Listing
March 2012

Inoperable stage III non-small cell lung cancer: Current treatment and role of vinorelbine.

Authors:
Mariano Provencio Dolores Isla Antonio Sánchez Blanca Cantos

J Thorac Dis 2011 Sep;3(3):197-204

Department of Medical Oncology, University Hospital Puerta de Hierro, Madrid, Spain;

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http://www.jthoracdis.com/article/view/132/
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http://dx.doi.org/10.3978/j.issn.2072-1439.2011.01.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256525PMC
September 2011

SEOM clinical guidelines for the treatment of oesophageal cancer.

Authors:
Javier Gallego Andrés Cervantes Carles Pericay Dolores Isla

Clin Transl Oncol 2011 Aug;13(8):520-4

Servicio de Oncología Médica, Hospital General Universitario de Elche, Elche, Alicante, Spain.

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http://dx.doi.org/10.1007/s12094-011-0691-0DOI Listing
August 2011

SEOM clinical guidelines for the treatment of anal cancer.

Authors:
Joan Maurel Carlos Fernández-Martos Jaime Feliu Dolores Isla

Clin Transl Oncol 2011 Aug;13(8):525-7

Medical Oncology Department, Hospital Clinic i Provincial de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12094-011-0692-zDOI Listing
August 2011

SEOM clinical guidelines for the treatment of pancreatic cancer.

Authors:
Carlos Gómez-Martín Manuel Hidalgo Josep Tabernero Dolores Isla

Clin Transl Oncol 2011 Aug;13(8):528-35

Servicio de Oncología Médica, Hospital Universitario 12 de Octubre, Madrid, Spain.

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http://dx.doi.org/10.1007/s12094-011-0693-yDOI Listing
August 2011

Hepatocellular and biliary tract carcinomas: SEOM clinical guidelines.

Authors:
Jaime Feliu Javier Sastre Joan Maurel Dolores Isla

Clin Transl Oncol 2011 Aug;13(8):536-44

Medical Oncology Department, Hospital Universitario La Paz (IdiPAZ), RETICC, Madrid, Spain.

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http://dx.doi.org/10.1007/s12094-011-0694-xDOI Listing
August 2011

SEOM clinical guidelines for the diagnosis and treatment of gastroenteropancreatic neuroendocrine tumours (GEP NETS).

Authors:
Rocío García-Carbonero Ramón Salazar Isabel Sevilla Dolores Isla

Clin Transl Oncol 2011 Aug;13(8):545-51

Medical Oncology Department, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.

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http://dx.doi.org/10.1007/s12094-011-0695-9DOI Listing
August 2011

SEOM clinical guidelines for the treatment of invasive bladder cancer.

Authors:
Rafael Morales Albert Font Joan Carles Dolores Isla

Clin Transl Oncol 2011 Aug;13(8):552-9

Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12094-011-0696-8DOI Listing
August 2011

SEOM clinical guidelines for diagnosis and treatment of testicular seminoma (2010).

Authors:
Jorge Aparicio Javier Sastre José Ramón Germà Dolores Isla

Clin Transl Oncol 2011 Aug;13(8):560-4

Servicio de Oncología Médica, Hospital Universitario La Fe, Valencia, Spain.

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http://dx.doi.org/10.1007/s12094-011-0697-7DOI Listing
August 2011

SEOM guidelines: non-seminomatous germ cell cancer (NSGCC).

Authors:
Pablo Maroto Xavier Garcí Del Muro Javier Sastre Dolores Isla

Clin Transl Oncol 2011 Aug;13(8):565-8

Servicio de Oncología Médica, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12094-011-0698-6DOI Listing
August 2011

SEOM guidelines for the treatment of malignant pleural mesothelioma.

Authors:
Pilar Lianes Jordi Remon Isabel Bover Dolores Isla

Clin Transl Oncol 2011 Aug;13(8):569-73

Servicio de Oncología Médica, Hospital de Mataró, Mataró, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12094-011-0699-5DOI Listing
August 2011

SEOM clinical guidelines for the treatment of thyroid cancer.

Authors:
Javier Martínez Trufero Jaume Capdevilla Juan Jesús Cruz Dolores Isla

Clin Transl Oncol 2011 Aug;13(8):574-9

Servicio de Oncología Médica, Hospital Universitario Miguel Servet, Zaragoza, Spain.

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http://dx.doi.org/10.1007/s12094-011-0700-3DOI Listing
August 2011

SEOM clinical guidelines for hereditary cancer.

Authors:
Begoña Graña Enrique Lastra Gemma Llort Joan Brunet Dolores Isla

Clin Transl Oncol 2011 Aug;13(8):580-6

High Risk and Cancer Prevention Unit, Medical Oncology Department, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.

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http://dx.doi.org/10.1007/s12094-011-0701-2DOI Listing
August 2011

SEOM clinical guidelines for using molecular markers in clinical practice.

Authors:
Virginia Arrazubi Roberto Pazo Dolores Isla José Luis Pérez Gracia

Clin Transl Oncol 2011 Aug;13(8):587-91

Medical Oncology Department, Hospital de Navarra, Pamplona, Navarra, Spain.

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http://link.springer.com/10.1007/s12094-011-0702-1
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http://dx.doi.org/10.1007/s12094-011-0702-1DOI Listing
August 2011

SEOM guidelines on thrombosis in cancer patients.

Authors:
Andrés J Muñoz Nuria Viñolas Ricardo Cubedo Dolores Isla

Clin Transl Oncol 2011 Aug;13(8):592-6

Servicio de Oncología Médica Hospital General Universitario Gregorio MarañónC/ Dr. Esquerdo, 46ES-28007 Madrid, Spain.

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http://dx.doi.org/10.1007/s12094-011-0703-0DOI Listing
August 2011

Treatment patterns, use of resources, and costs of advanced non-small-cell lung cancer patients in Spain: results from a Delphi panel.

Authors:
Dolores Isla Nuria González-Rojas Diana Nieves Max Brosa Henrik W Finnern

Clin Transl Oncol 2011 Jul;13(7):460-71

Medical Oncology Department, University Hospital Lozano Blesa, Zaragoza, Spain.

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http://link.springer.com/10.1007/s12094-011-0683-0
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http://dx.doi.org/10.1007/s12094-011-0683-0DOI Listing
July 2011

First-line therapy and methylation status of CHFR in serum influence outcome to chemotherapy versus EGFR tyrosine kinase inhibitors as second-line therapy in stage IV non-small-cell lung cancer patients.

Authors:
Fernanda Salazar Miguel Angel Molina Maria Sanchez-Ronco Teresa Moran Jose Luis Ramirez Jose Miguel Sanchez Rolf Stahel Pilar Garrido Manuel Cobo Dolores Isla Jordi Bertran-Alamillo Bartomeu Massuti Felipe Cardenal Christian Manegold Pilar Lianes Jose Manuel Trigo Jose Javier Sanchez Miquel Taron Rafael Rosell

Lung Cancer 2011 Apr 11;72(1):84-91. Epub 2010 Aug 11.

Catalan Institute of Oncology, Badalona, Spain.

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http://linkinghub.elsevier.com/retrieve/pii/S016950021000368
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http://dx.doi.org/10.1016/j.lungcan.2010.07.008DOI Listing
April 2011

Pretreatment EGFR T790M mutation and BRCA1 mRNA expression in erlotinib-treated advanced non-small-cell lung cancer patients with EGFR mutations.

Authors:
Rafael Rosell Miguel Angel Molina Carlota Costa Sara Simonetti Ana Gimenez-Capitan Jordi Bertran-Alamillo Clara Mayo Teresa Moran Pedro Mendez Felipe Cardenal Dolores Isla Mariano Provencio Manuel Cobo Amelia Insa Rosario Garcia-Campelo Noemi Reguart Margarita Majem Santiago Viteri Enric Carcereny Ruth Porta Bartomeu Massuti Cristina Queralt Itziar de Aguirre Jose Miguel Sanchez Maria Sanchez-Ronco Jose Luis Mate Aurelio Ariza Susana Benlloch Jose Javier Sanchez Trever G Bivona Charles L Sawyers Miquel Taron

Clin Cancer Res 2011 Mar 13;17(5):1160-8. Epub 2011 Jan 13.

Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain.

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http://clincancerres.aacrjournals.org/content/17/5/1160.full
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-10-2158DOI Listing
March 2011

Genome-wide significant association between a sequence variant at 15q15.2 and lung cancer risk.

Authors:
Thorunn Rafnar Patrick Sulem Soren Besenbacher Daniel F Gudbjartsson Carlo Zanon Julius Gudmundsson Simon N Stacey Jelena P Kostic Thorgeir E Thorgeirsson Gudmar Thorleifsson Hjordis Bjarnason Halla Skuladottir Tomas Gudbjartsson Helgi J Isaksson Dolores Isla Laura Murillo Maria D García-Prats Angeles Panadero Katja K H Aben Sita H Vermeulen Henricus F M van der Heijden William J Feser York E Miller Paul A Bunn Augustine Kong Holly J Wolf Wilbur A Franklin Jose I Mayordomo Lambertus A Kiemeney Steinn Jonsson Unnur Thorsteinsdottir Kari Stefansson

Cancer Res 2011 Feb 8;71(4):1356-61. Epub 2011 Feb 8.

deCODE genetics, Department of Medical Oncology, Landspitali-University Hospital, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-2852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077097PMC
February 2011

Adjuvant docetaxel for high-risk, node-negative breast cancer.

Authors:
Miguel Martín Miguel A Seguí Antonio Antón Amparo Ruiz Manuel Ramos Encarna Adrover Ignacio Aranda Alvaro Rodríguez-Lescure Regina Grosse Lourdes Calvo Agustí Barnadas Dolores Isla Purificación Martinez del Prado Manuel Ruiz Borrego Jerzy Zaluski Angels Arcusa Montserrat Muñoz José M López Vega José R Mel Blanca Munarriz Cristina Llorca Carlos Jara Emilio Alba Jesús Florián Junfang Li José A López García-Asenjo Amparo Sáez María José Rios Sergio Almenar Gloria Peiró Ana Lluch

N Engl J Med 2010 Dec;363(23):2200-10

Hospital General Universitario Gregorio Marañón, Madrid, Spain.

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http://dx.doi.org/10.1056/NEJMoa0910320DOI Listing
December 2010

Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer.

Authors:
Sara Simonetti Miguel Angel Molina Cristina Queralt Itziar de Aguirre Clara Mayo Jordi Bertran-Alamillo José Javier Sanchez Jose Luis Gonzalez-Larriba Ulpiano Jimenez Dolores Isla Teresa Moran Santiago Viteri Carlos Camps Rosario Garcia-Campelo Bartomeu Massuti Susana Benlloch Santiago Ramon y Cajal Miquel Taron Rafael Rosell

J Transl Med 2010 Dec 18;8:135. Epub 2010 Dec 18.

Pangaea Biotech, USP Dexeus University Institute, Barcelona, Spain.

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http://dx.doi.org/10.1186/1479-5876-8-135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016260PMC
December 2010

Preoperative chemotherapy plus surgery versus surgery plus adjuvant chemotherapy versus surgery alone in early-stage non-small-cell lung cancer.

Authors:
Enriqueta Felip Rafael Rosell José Antonio Maestre José Manuel Rodríguez-Paniagua Teresa Morán Julio Astudillo Guillermo Alonso José Manuel Borro José Luis González-Larriba Antonio Torres Carlos Camps Ricardo Guijarro Dolores Isla Rafael Aguiló Vicente Alberola José Padilla Abel Sánchez-Palencia José Javier Sánchez Eduardo Hermosilla Bartomeu Massuti

J Clin Oncol 2010 Jul 1;28(19):3138-45. Epub 2010 Jun 1.

Vall d'Hebron University Hospital, Barcelona, Spain.

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http://dx.doi.org/10.1200/JCO.2009.27.6204DOI Listing
July 2010

Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium.

Authors:
Therese Truong Rayjean J Hung Christopher I Amos Xifeng Wu Heike Bickeböller Albert Rosenberger Wiebke Sauter Thomas Illig H-Erich Wichmann Angela Risch Hendrik Dienemann Rudolph Kaaks Ping Yang Ruoxiang Jiang John K Wiencke Margaret Wrensch Helen Hansen Karl T Kelsey Keitaro Matsuo Kazuo Tajima Ann G Schwartz Angie Wenzlaff Adeline Seow Chen Ying Andrea Staratschek-Jox Peter Nürnberg Erich Stoelben Jürgen Wolf Philip Lazarus Joshua E Muscat Carla J Gallagher Shanbeh Zienolddiny Aage Haugen Henricus F M van der Heijden Lambertus A Kiemeney Dolores Isla Jose Ignacio Mayordomo Thorunn Rafnar Kari Stefansson Zuo-Feng Zhang Shen-Chih Chang Jin Hee Kim Yun-Chul Hong Eric J Duell Angeline S Andrew Flavio Lejbkowicz Gad Rennert Heiko Müller Hermann Brenner Loïc Le Marchand Simone Benhamou Christine Bouchardy M Dawn Teare Xiaoyan Xue John McLaughlin Geoffrey Liu James D McKay Paul Brennan Margaret R Spitz

J Natl Cancer Inst 2010 Jul 14;102(13):959-71. Epub 2010 Jun 14.

Genetic Epidemiology Group, International Agency for Research on Cancer, 150 Cours Albert Thomas, Lyon Cedex 08, France.

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http://jnci.oxfordjournals.org/content/102/13/959.full.pdf
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http://jnci.oxfordjournals.org/cgi/doi/10.1093/jnci/djq178
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http://dx.doi.org/10.1093/jnci/djq178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897877PMC
July 2010

Blood-based CHRNA3 single nucleotide polymorphism and outcome in advanced non-small-cell lung cancer patients.

Authors:
Enric Carcereny Jose Luis Ramirez Maria Sanchez-Ronco Dolores Isla Manuel Cobo Teresa Moran Itziar de Aguirre Tatsuro Okamoto Jia Wei Mariano Provencio Guillermo Lopez-Vivanco Carlos Camps Manuel Domine Vicente Alberola Jose Miguel Sanchez Bartomeu Massuti Pedro Mendez Miquel Taron Rafael Rosell

Lung Cancer 2010 Jun 5;68(3):491-7. Epub 2009 Sep 5.

Catalan Institute of Oncology, Badalona, Spain.

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http://dx.doi.org/10.1016/j.lungcan.2009.08.004DOI Listing
June 2010

Lung cancer and treatment in elderly patients: the Achilles Study.

Authors:
Mariano Provencio Carlos Camps Vicente Alberola Bertomeu Massutti Nuria Viñolas Dolores Isla Manuel Dómine Isabel Millán Manuel Cobo Rafael Rosell

Lung Cancer 2009 Oct 4;66(1):103-6. Epub 2009 Feb 4.

Department of Medical Oncology, Hospital Puerta de Hierro, Madrid 28222, Spain.

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http://dx.doi.org/10.1016/j.lungcan.2008.12.021DOI Listing
October 2009

Screening for epidermal growth factor receptor mutations in lung cancer.

Authors:
Rafael Rosell Teresa Moran Cristina Queralt Rut Porta Felipe Cardenal Carlos Camps Margarita Majem Guillermo Lopez-Vivanco Dolores Isla Mariano Provencio Amelia Insa Bartomeu Massuti Jose Luis Gonzalez-Larriba Luis Paz-Ares Isabel Bover Rosario Garcia-Campelo Miguel Angel Moreno Silvia Catot Christian Rolfo Noemi Reguart Ramon Palmero José Miguel Sánchez Roman Bastus Clara Mayo Jordi Bertran-Alamillo Miguel Angel Molina Jose Javier Sanchez Miquel Taron

N Engl J Med 2009 Sep 19;361(10):958-67. Epub 2009 Aug 19.

Catalan Institute of Oncology and Autonomous University of Barcelona, Hospital Germans Trias i Pujol, Barcelona, Spain.

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http://dx.doi.org/10.1056/NEJMoa0904554DOI Listing
September 2009

Customized treatment in non-small-cell lung cancer based on EGFR mutations and BRCA1 mRNA expression.

Authors:
Rafael Rosell Laia Perez-Roca Jose Javier Sanchez Manuel Cobo Teresa Moran Imane Chaib Mariano Provencio Manuel Domine Maria Angeles Sala Ulpiano Jimenez Pilar Diz Isidoro Barneto Jose Antonio Macias Ramon de Las Peñas Silvia Catot Dolores Isla Jose Miguel Sanchez Rafael Ibeas Guillermo Lopez-Vivanco Juana Oramas Pedro Mendez Noemi Reguart Remei Blanco Miquel Taron

PLoS One 2009 5;4(5):e5133. Epub 2009 May 5.

Catalan Institute of Oncology, Badalona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005133PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673583PMC
July 2009

Clinical-molecular factors predicting response and survival for tyrosine-kinase inhibitors.

Authors:
Mariano Provencio Rosario García-Campelo Dolores Isla Javier de Castro

Clin Transl Oncol 2009 Jul;11(7):428-36

Medical Oncology Department, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1007/s12094-009-0381-3DOI Listing
July 2009

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.

Authors:
Thorunn Rafnar Patrick Sulem Simon N Stacey Frank Geller Julius Gudmundsson Asgeir Sigurdsson Margret Jakobsdottir Hafdis Helgadottir Steinunn Thorlacius Katja K H Aben Thorarinn Blöndal Thorgeir E Thorgeirsson Gudmar Thorleifsson Kristleifur Kristjansson Kristin Thorisdottir Rafn Ragnarsson Bardur Sigurgeirsson Halla Skuladottir Tomas Gudbjartsson Helgi J Isaksson Gudmundur V Einarsson Kristrun R Benediktsdottir Bjarni A Agnarsson Karl Olafsson Anna Salvarsdottir Hjordis Bjarnason Margret Asgeirsdottir Kari T Kristinsson Sigurborg Matthiasdottir Steinunn G Sveinsdottir Silvia Polidoro Veronica Höiom Rafael Botella-Estrada Kari Hemminki Peter Rudnai D Timothy Bishop Marcello Campagna Eliane Kellen Maurice P Zeegers Petra de Verdier Ana Ferrer Dolores Isla Maria Jesus Vidal Raquel Andres Berta Saez Pablo Juberias Javier Banzo Sebastian Navarrete Alejandro Tres Donghui Kan Annika Lindblom Eugene Gurzau Kvetoslava Koppova Femmie de Vegt Jack A Schalken Henricus F M van der Heijden Hans J Smit René A Termeer Egbert Oosterwijk Onno van Hooij Eduardo Nagore Stefano Porru Gunnar Steineck Johan Hansson Frank Buntinx William J Catalona Giuseppe Matullo Paolo Vineis Anne E Kiltie José I Mayordomo Rajiv Kumar Lambertus A Kiemeney Michael L Frigge Thorvaldur Jonsson Hafsteinn Saemundsson Rosa B Barkardottir Eirikur Jonsson Steinn Jonsson Jon H Olafsson Jeffrey R Gulcher Gisli Masson Daniel F Gudbjartsson Augustine Kong Unnur Thorsteinsdottir Kari Stefansson

Nat Genet 2009 Feb 18;41(2):221-7. Epub 2009 Jan 18.

deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525478PMC
February 2009

Retrospective study of efficacy and toxicity on patients older than 70 years within a randomized clinical trial of two cisplatin-based combinations in patients with small-cell lung cancer.

Authors:
María José Safont Angel Artal-Cortes Rafael Sirera José Gómez-Codina José Luis González-Larriba Isidoro Barneto Alfredo Carrato Dolores Isla Rafael Rosell Carlos Camps

Lung Cancer 2009 Jan 13;63(1):83-7. Epub 2008 Jun 13.

Servicio de Oncología Médica, Hospital General Universitario de Valencia, Spain.

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http://dx.doi.org/10.1016/j.lungcan.2008.04.015DOI Listing
January 2009

Prognostic significance and diagnostic value of protein S-100 and tyrosinase in patients with malignant melanoma.

Authors:
Raquel Andrés Jose I Mayordomo Carmen Visus Dolores Isla Javier Godino Pilar Escudero Alberto Saenz Eugenia Ortega Rodrigo Lastra Julio Lambea Elena Aguirre Luis Elosegui Ivan Marcos Manuel Ruiz-Echarri Esther Millastre Berta Sáez-Gutierrez Laura Asin Maria J Vidal Ana Ferrer Armando Giner Luis Larrad Francisco J Carapeto Alejandro Tres

Am J Clin Oncol 2008 Aug;31(4):335-9

Servicio de Oncología Médica, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.

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http://dx.doi.org/10.1097/COC.0b013e318162f11eDOI Listing
August 2008

Randomized phase II study of cisplatin and 5-FU continuous infusion (PF) versus cisplatin, UFT and vinorelbine (UFTVP) as induction chemotherapy in locally advanced squamous cell head and neck cancer (LA-SCHNC).

Authors:
Fernando Rivera M Eugenia Vega-Villegas Marta López-Brea Dolores Isla Marta Mayorga Piedad Galdós Antonio Rubio Adolfo Del Valle Fe García-Reija Belen García-Montesinos Julio Rodríguez-Iglesias Jose Mayordomo Julio Rama Ramón Saiz-Bustillo Jaime Sanz-Ortiz

Cancer Chemother Pharmacol 2008 Jul 28;62(2):253-61. Epub 2007 Sep 28.

Department of Medical Oncology, Hospital Universitario Marqués de Valdecilla, 39008, Santander, Spain.

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http://dx.doi.org/10.1007/s00280-007-0599-0DOI Listing
July 2008

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.

Authors:
Thorgeir E Thorgeirsson Frank Geller Patrick Sulem Thorunn Rafnar Anna Wiste Kristinn P Magnusson Andrei Manolescu Gudmar Thorleifsson Hreinn Stefansson Andres Ingason Simon N Stacey Jon T Bergthorsson Steinunn Thorlacius Julius Gudmundsson Thorlakur Jonsson Margret Jakobsdottir Jona Saemundsdottir Olof Olafsdottir Larus J Gudmundsson Gyda Bjornsdottir Kristleifur Kristjansson Halla Skuladottir Helgi J Isaksson Tomas Gudbjartsson Gregory T Jones Thomas Mueller Anders Gottsäter Andrea Flex Katja K H Aben Femmie de Vegt Peter F A Mulders Dolores Isla Maria J Vidal Laura Asin Berta Saez Laura Murillo Thorsteinn Blondal Halldor Kolbeinsson Jon G Stefansson Ingunn Hansdottir Valgerdur Runarsdottir Roberto Pola Bengt Lindblad Andre M van Rij Benjamin Dieplinger Meinhard Haltmayer Jose I Mayordomo Lambertus A Kiemeney Stefan E Matthiasson Hogni Oskarsson Thorarinn Tyrfingsson Daniel F Gudbjartsson Jeffrey R Gulcher Steinn Jonsson Unnur Thorsteinsdottir Augustine Kong Kari Stefansson

Nature 2008 Apr;452(7187):638-642

deCODE Genetics, Reykjavik Iceland.

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http://dx.doi.org/10.1038/nature06846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539558PMC
April 2008

Early intervention with epoetin beta prevents severe anaemia in lung cancer patients receiving platinum-based chemotherapy: a subgroup analysis of the NeoPrevent study.

Authors:
Javier de Castro Cristóbal Belda-Iniesta Dolores Isla Manuel Dómine Alfredo Sánchez Eduard Batiste Manuel González Barón

Lung Cancer 2008 Feb 17;59(2):211-8. Epub 2007 Sep 17.

Servicio de Oncología Médica, Hospital Universitario La Paz (Madrid), Paseo de la Castellana, 261, 28046 Madrid, Spain.

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http://dx.doi.org/10.1016/j.lungcan.2007.08.006DOI Listing
February 2008

Platinum resistance related to a functional NER pathway.

Authors:
Rafael Rosell Pedro Mendez Dolores Isla Miquel Taron

J Thorac Oncol 2007 Dec;2(12):1063-6

Medical Oncology Service, Catalan Institute of Oncology, Badalona, Spain.

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http://dx.doi.org/10.1097/JTO.0b013e31815ba2a1DOI Listing
December 2007

Long-term survival associated with complete resection after induction chemotherapy in stage IIIA (N2) and IIIB (T4N0-1) non small-cell lung cancer patients: the Spanish Lung Cancer Group Trial 9901.

Authors:
Pilar Garrido José Luis González-Larriba Amelia Insa Mariano Provencio Antonio Torres Dolores Isla José Miguel Sanchez Felipe Cardenal Manuel Domine Jose Ramon Barcelo Vicente Tarrazona Andres Varela Rafael Aguilo Julio Astudillo Ignacio Muguruza Angel Artal Florentino Hernando-Trancho Bartomeu Massuti Maria Sanchez-Ronco Rafael Rosell

J Clin Oncol 2007 Oct;25(30):4736-42

Hospital Ramon y Cajal, Madrid, Spain.

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http://dx.doi.org/10.1200/JCO.2007.12.0014DOI Listing
October 2007

Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in non-small-cell lung cancer.

Authors:
Manuel Cobo Dolores Isla Bartomeu Massuti Ana Montes Jose Miguel Sanchez Mariano Provencio Nuria Viñolas Luis Paz-Ares Guillermo Lopez-Vivanco Miguel Angel Muñoz Enriqueta Felip Vicente Alberola Carlos Camps Manuel Domine Jose Javier Sanchez Maria Sanchez-Ronco Kathleen Danenberg Miquel Taron David Gandara Rafael Rosell

J Clin Oncol 2007 Jul;25(19):2747-54

Hospital Carlos Haya, Malaga, Spain.

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http://dx.doi.org/10.1200/JCO.2006.09.7915DOI Listing
July 2007

Early intervention with epoetin beta prevents severe anaemia in patients with solid tumours receiving platinum-based chemotherapy: results of the NeoPrevent study.

Authors:
Javier de Castro Amalio Ordóñez Dolores Isla Alfredo Sánchez Antonio Arrivi José Luis Manzano Manuel González Barón

Cancer Chemother Pharmacol 2007 Jan 28;59(1):35-42. Epub 2006 Jul 28.

Servicio de Oncología Médica, Hospital Universitario La Paz (Madrid), Paseo de la Castellana, 261, 28046, Madrid, Spain.

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http://dx.doi.org/10.1007/s00280-006-0251-4DOI Listing
January 2007

Epidermal growth factor receptor activation: how exon 19 and 21 mutations changed our understanding of the pathway.

Authors:
Rafael Rosell Miquel Taron Noemi Reguart Dolores Isla Teresa Moran

Clin Cancer Res 2006 Dec;12(24):7222-31

Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-0627DOI Listing
December 2006

Phase III study comparing cisplatin plus fluorouracil to paclitaxel, cisplatin, and fluorouracil induction chemotherapy followed by chemoradiotherapy in locally advanced head and neck cancer.

Authors:
Ricardo Hitt Antonio López-Pousa Javier Martínez-Trufero Vicente Escrig Joan Carles Alfredo Rizo Dolores Isla M Eugenia Vega Juan L Martí Francisco Lobo Pedro Pastor Vicente Valentí Joaquín Belón Miguel A Sánchez Carlos Chaib Cinta Pallarés Antonio Antón Andrés Cervantes Luis Paz-Ares Hernán Cortés-Funes

J Clin Oncol 2005 Dec 7;23(34):8636-45. Epub 2005 Nov 7.

Servicio de Oncología Médica, Hospital Universitario 12 de Octubre de Madrid, Carretera de Andalucía, km 5,400, 28041, Madrid, Spain.

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http://dx.doi.org/10.1200/JCO.2004.00.1990DOI Listing
December 2005

Applications of genomics in NSCLC.

Authors:
Rafael Rosella Manuel Cobo Dolores Isla Jose Miguel Sanchez Miquel Taron Giuseppe Altavilla Mariacarmela Santarpia Teresa Moran Silvia Catot Olatz Etxaniza

Lung Cancer 2005 Dec;50S2:S33-S40

Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Ctra Canyet, s/n Badalona (Barcelona), Spain.

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December 2005

Applications of genomics in NSCLC.

Authors:
Rafael Rosell Manuel Cobo Dolores Isla Jose Miguel Sanchez Miquel Taron Giuseppe Altavilla Mariacarmela Santarpia Teresa Moran Silvia Catot Olatz Etxaniz

Lung Cancer 2005 Dec;50 Suppl 2:S33-40

Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Ctra Canyet, s/n, 08916 Badalona, Barcelona, Spain.

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December 2005

Gemcitabine/capecitabine in patients with metastatic breast cancer pretreated with anthracyclines and taxanes.

Authors:
Raquel Andres Jose Ignacio Mayordomo Ricardo Lara Rodrigo Lastra Eugenia Ortega Eduardo Polo Julio Lambea Dolores Isla Alberto Saenz-Cusi Pilar Escudero Alejandro Tres

Clin Breast Cancer 2005 Jun;6(2):158-62

Division of Medical Oncology, Hospital Clinico Universitario, Zaragoza, Spain.

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http://dx.doi.org/10.3816/cbc.2005.n.018DOI Listing
June 2005

Prognostic value of serum S-100B in malignant melanoma.

Authors:
Raquel Andrés José I Mayordomo Pedro Zaballos Javier Rodino Dolores Isla Pilar Escudero Luis Elosegui Elena Filipovich Alberto Saenz Eduardo Polo Alejandro Tres

Tumori 2004 Nov-Dec;90(6):607-10

Division of Medical Oncology, University Hospital, Zaragoza, Spain.

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March 2005

Prospective randomized phase III trial of etoposide/cisplatin versus high-dose epirubicin/cisplatin in small-cell lung cancer.

Authors:
Angel Artal-Cortés Jose Gomez-Codina Jose Luis Gonzalez-Larriba Isidoro Barneto Alfredo Carrato Dolores Isla Carlos Camps Carlos Garcia-Giron Albert Font Alfredo Meana Maria Lomas Catalina Vadell Antonio Arrivi Carmen Alonso Immaculada Maestu Joaquin Campbell Rafael Rosell

Clin Lung Cancer 2004 Nov;6(3):175-83

Hospital Universitario Miguel Servet, Zaragosa, Madrid Spain.

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http://dx.doi.org/10.3816/clc.2004.n.031DOI Listing
November 2004

The promise of pharmacogenomics: gemcitabine and pemetrexed.

Authors:
Rafael Rosell Miquel Taron Jose Miguel Sanchez Teresa Moran Noemi Reguart Benjamin Besse Dolores Isla Bartomeu Massuti Vicente Alberola Jose Javier Sanchez

Oncology (Williston Park) 2004 Nov;18(13 Suppl 8):70-6

Medical Oncology Service, Hospital Germans Trias i Pujol, Badalona, Spain.

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November 2004

Effect of the methylenetetrahydrofolate reductase C677T polymorphism on patients with cisplatin/gemcitabine-treated stage IV non-small-cell lung cancer.

Authors:
Vicente Alberola Carme Sarries Rafael Rosell Miquel Taron Ramon de las Peñas Carlos Camps Bartomeu Massuti Amelia Insa Ramon Garcia-Gomez Dolores Isla Angel Artal Miguel Angel Muñoz Manuel Cobo Isabel Bover Jose Luis Gonzalez-Larria Josefa Terrasa Daniel Almenar Ramon Barcelo Pilar Diz Maria Sanchez-Ronco Jose Javier Sanchez

Clin Lung Cancer 2004 May;5(6):360-5

Medical Oncology Service, Hospital Arnau de Vilanova, Valencia, Spain.

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http://dx.doi.org/10.3816/clc.2004.n.014DOI Listing
May 2004

Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients.

Authors:
Rafael Rosell Kathleen D Danenberg Vincente Alberola Gerold Bepler Jose Javier Sanchez Carlos Camps Mariano Provencio Dolores Isla Miquel Taron Pilar Diz Angel Artal

Clin Cancer Res 2004 Feb;10(4):1318-25

Medical Oncology Service, Institut Català d'Oncologia, Hospital Germans Trias i Pujol, Barcelona, Spain.

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http://dx.doi.org/10.1158/1078-0432.ccr-03-0156DOI Listing
February 2004

Case 4. Hypertrophic osteoarthropathy associated with pulmonary metastasis of uterine leiomyosarcoma.

Authors:
Raquel Andrés Alberto Saenz José I Mayordomo Pedro Zaballos Dolores Isla Pilar Escudero Ignacio Alvarez Eduardo Polo Ricardo Lara Alejandro Tres

J Clin Oncol 2003 Sep;21(18):3540-1

Division of Medical Oncology, University Hospital, Zaragoza, Spain.

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http://dx.doi.org/10.1200/JCO.2003.11.080DOI Listing
September 2003

MDR-1 C3435T genetic polymorphism and tobacco-related lung cancer.

Authors:
Blanca Sinués Ana Fanlo Maria Luisa Bernal Esteban Mayayo Salvador Bello Encarna Rubio Dolores Isla

Oncology 2003 ;64(2):183-5

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http://dx.doi.org/10.1159/000067770DOI Listing
March 2003