Do-Hyun Nam

Do-Hyun Nam

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Do-Hyun Nam

Do-Hyun Nam

Publications by authors named "Do-Hyun Nam"

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100Publications

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Corrigendum to "Reconstructive outcome of intraoperative cerebrospinal fluid leak after endoscopic endonasal surgery for tumors involving skull base" [J. Clin. Neurosci. 45 (2017) 227-231].

J Clin Neurosci 2018 Dec 2;58:235. Epub 2018 Oct 2.

Department of Neurosurgery, Endoscopic Skull Base Surgery Clinic, Brain Tumor Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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December 2018

The influence of histology on the response of brain metastases to gamma knife radiosurgery: a propensity score-matched study.

Acta Neurochir (Wien) 2018 Dec 9;160(12):2379-2386. Epub 2018 Nov 9.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.

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December 2018

Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor.

Cell 2018 Nov 18;175(6):1665-1678.e18. Epub 2018 Oct 18.

Beijing Neurosurgical Institute, Capital Medical University, 100050 Beijing, China; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 100050 Beijing, China; Center of Brain Tumor, Beijing Institute for Brain Disorders, 100069 Beijing, China; China National Clinical Research Center for Neurological Diseases, 100050 Beijing, China. Electronic address:

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November 2018

Apparent Diffusion Coefficient as a Predictive Biomarker for Survival in Patients with Treatment-Naive Glioblastoma Using Quantitative Multiparametric Magnetic Resonance Profiling.

World Neurosurg 2018 Nov 1. Epub 2018 Nov 1.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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November 2018

Endoscopic endonasal vs. transorbital surgery for middle cranial fossa tumors: Comparison of clinical outcomes based on surgical corridors.

World Neurosurg 2018 Nov 20. Epub 2018 Nov 20.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. Electronic address:

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November 2018

Clinical and ophthalmological outcome of endoscopic transorbital surgery for cranioorbital tumors.

J Neurosurg 2018 Sep 14:1-9. Epub 2018 Sep 14.

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine; and.

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September 2018

Drug repurposing screening identifies bortezomib and panobinostat as drugs targeting cancer associated fibroblasts (CAFs) by synergistic induction of apoptosis.

Invest New Drugs 2018 08 18;36(4):545-560. Epub 2018 Jan 18.

Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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August 2018

Significant therapeutic effects of adult human multipotent neural cells on spinal cord injury.

Stem Cell Res 2018 Aug 19;31:71-78. Epub 2018 Jul 19.

Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, 06351, South Korea; Stem Cell and Regenerative Medicine Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul 06351, South Korea; Department of Anatomy & Cell Biology, Sungkyunkwan University School of Medicine, Suwon 16419, South Korea; Single Cell Network Research Center, Sungkyunkwan University School of Medicine, Suwon, 16419, South Korea; Samsung Biomedical Research Institute, Samsung Medical Center, Seoul 06351, South Korea. Electronic address:

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August 2018

In vivo distribution of U87MG cells injected into the lateral ventricle of rats with spinal cord injury.

PLoS One 2018 16;13(8):e0202307. Epub 2018 Aug 16.

Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea.

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August 2018

TP53-dependence on the effect of doxorubicin and Src inhibitor combination therapy.

Tumour Biol 2018 Aug;40(8):1010428318794217

1 Department of Orthopaedic Surgery, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea.

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August 2018

Anti-SEMA3A Antibody: A Novel Therapeutic Agent to Suppress Glioblastoma Tumor Growth.

Cancer Res Treat 2018 Jul 10;50(3):1009-1022. Epub 2017 Nov 10.

Institute for Refractory Cancer Research, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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July 2018

High-Dose Compound Heat Map for 3D-Cultured Glioblastoma Multiforme Cells in a Micropillar and Microwell Chip Platform.

Biomed Res Int 2017 18;2017:7218707. Epub 2017 Oct 18.

Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul 06351, Republic of Korea.

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July 2018

3D Cell-Based High-Content Screening (HCS) Using a Micropillar and Microwell Chip Platform.

Anal Chem 2018 Jul 29;90(14):8354-8361. Epub 2018 Jun 29.

Department of Biomedical Engineering , Konyang University , Daejeon , 35365 , Republic of Korea.

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July 2018

Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.

Cancer Cell 2018 Jul 21;34(1):119-135.e10. Epub 2018 Jun 21.

Department of Neurosurgery, University of Alabama at Birmingham, Wallace Tumor Institute, 410F, 1720 2nd Avenue S, Birmingham, AL 35294-3300, USA; Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address:

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July 2018

Potent effect of the MDM2 inhibitor AMG232 on suppression of glioblastoma stem cells.

Cell Death Dis 2018 Jul 18;9(8):792. Epub 2018 Jul 18.

Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, 06351, Korea.

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July 2018

Is Low-Lying Optic Chiasm an Obstacle to an Endoscopic Endonasal Approach for Retrochiasmatic Craniopharyngiomas? (Korean Society of Endoscopic Neurosurgery -003).

World Neurosurg 2018 Jun 7;114:e306-e316. Epub 2018 Mar 7.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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June 2018

Astrocyte-derived CCL20 reinforces HIF-1-mediated hypoxic responses in glioblastoma by stimulating the CCR6-NF-κB signaling pathway.

Oncogene 2018 Jun 14;37(23):3070-3087. Epub 2018 Mar 14.

Department of Biomedical Sciences, BK21-plus education program, Seoul National University College of Medicine, Seoul, Korea.

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June 2018

Identification of transcriptome signature for predicting clinical response to bevacizumab in recurrent glioblastoma.

Cancer Med 2018 May 23;7(5):1774-1783. Epub 2018 Mar 23.

Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Korea.

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May 2018

Pharmacokinetics, Biodistribution, and Toxicity Evaluation of Anti-SEMA3A (F11) in Models.

Anticancer Res 2018 05;38(5):2803-2810

Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea

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May 2018

Selection of endoscopic or transcranial surgery for tuberculum sellae meningiomas according to specific anatomical features: a retrospective multicenter analysis (KOSEN-002).

J Neurosurg 2018 May 18:1-10. Epub 2018 May 18.

Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

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May 2018

Clinical and radiological outcomes of proactive Gamma Knife surgery for asymptomatic meningiomas compared with the natural course without intervention.

J Neurosurg 2018 May 18:1-10. Epub 2018 May 18.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; and.

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May 2018

TP53 gain-of-function mutation promotes inflammation in glioblastoma.

Cell Death Differ 2018 May 21. Epub 2018 May 21.

Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea.

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May 2018

Comparison of 1p and 19q status of glioblastoma by whole exome sequencing, array-comparative genomic hybridization, and fluorescence in situ hybridization.

Med Oncol 2018 Mar 29;35(5):60. Epub 2018 Mar 29.

Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

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March 2018

Genetic and Clinical Characteristics of Phyllodes Tumors of the Breast.

Transl Oncol 2018 Feb 13;11(1):18-23. Epub 2017 Nov 13.

Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 06351, Korea; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University, Seoul 06351, Korea; Biomedical Research Institute, Samsung Medical Center, Sungkyunkwan University, Seoul 06351, Korea. Electronic address:

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February 2018

Leptomeningeal enhancement on preoperative brain MRI in patients with glioblastoma and its clinical impact.

Asia Pac J Clin Oncol 2018 Feb 23. Epub 2018 Feb 23.

Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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February 2018

Prognostic Value of Ki-67 Labeling Index and Postoperative Radiotherapy in WHO Grade II Meningioma.

Am J Clin Oncol 2018 Jan;41(1):18-23

Department of Radiation Oncology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul.

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January 2018

Quantitative radiomic profiling of glioblastoma represents transcriptomic expression.

Oncotarget 2018 Jan 5;9(5):6336-6345. Epub 2018 Jan 5.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea.

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January 2018

Antitumor activity, pharmacokinetics, tumor-homing effect, and hepatotoxicity of a species cross-reactive c-Met antibody.

Biochem Biophys Res Commun 2017 12 14;494(1-2):409-415. Epub 2017 Sep 14.

Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul 06351, Republic of Korea; Institute for Refractory Cancer Research, Research Institute for Future Medicine, Samsung Medical Center, Seoul 06351, Republic of Korea; Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea. Electronic address:

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December 2017

Preclinical and clinical implications of promoter mutation in glioblastoma multiforme.

Oncol Lett 2017 Dec 16;14(6):8213-8219. Epub 2017 Oct 16.

Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul 06531, Republic of Korea.

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December 2017

Reconstructive outcome of intraoperative cerebrospinal fluid leak after endoscopic endonasal surgery for tumors involving skull base.

J Clin Neurosci 2017 Nov 29;45:227-231. Epub 2017 Jul 29.

Department of Neurosurgery, Endoscopic Skull Base Surgery Clinic, Brain Tumor Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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November 2017

Tumor Inhibitory Effect of IRCR201, a Novel Cross-Reactive c-Met Antibody Targeting the PSI Domain.

Int J Mol Sci 2017 Sep 13;18(9). Epub 2017 Sep 13.

Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul 06351, Korea.

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September 2017

Sensitive Tumorigenic Potential Evaluation of Adult Human Multipotent Neural Cells Immortalized by hTERT Gene Transduction.

PLoS One 2016 8;11(7):e0158639. Epub 2016 Jul 8.

Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea.

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August 2017

The role of STAT3 in glioblastoma progression through dual influences on tumor cells and the immune microenvironment.

Mol Cell Endocrinol 2017 08 12;451:53-65. Epub 2017 Jan 12.

Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul 06351, South Korea; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul 06351, South Korea; Departments of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, South Korea. Electronic address:

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August 2017

Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG.

Neuro Oncol 2017 Aug;19(8):1119-1126

Tel-Aviv Sourasky Medical Center, Tel-Aviv University; European Organization for Research and Treatment of Cancer, Brussels (EORTC); National Institutes of Health (M.R.M.); University of Alabama at Birmingham; Princess Margaret Cancer Centre, University of Toronto; Lausanne University Hospital; NRG Oncology Statistics and Data Management Center; Odette Cancer Centre and Sunnybrook Health Sciences Centre, University of Toronto; Samsung Medical Center, Sungkyunkwan University School of Medicine; Edinburgh Cancer Centre; Mayo Clinic; Robert-Janker Clinic at the University of Bonn Medical Centre, and MAASTRO clinic, GROW School for Oncology, Maastricht University Medical Centre; Miami Cancer Institute; Erasmus University Hospital; Dana-Farber Cancer Institute and Harvard Medical School; University of Zurich.

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August 2017

Outcome of Endoscopic Transsphenoidal Surgery for Acromegaly.

World Neurosurg 2017 Aug 29;104:272-278. Epub 2017 Apr 29.

Pituitary Center, Seoul National University College of Medicine, Seoul, Korea; Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea. Electronic address:

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August 2017

Optimal treatment of jugular foramen schwannomas: long-term outcome of a multidisciplinary approach for a series of 29 cases in a single institute.

Acta Neurochir (Wien) 2017 08 6;159(8):1517-1527. Epub 2017 Jun 6.

Department of Neurosurgery, Samsung Medical Center Sungkyunkwan University School of Medicine, 81 Ilwon-Ro, Gangnam-Gu, Seoul, 135-710, South Korea.

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August 2017

RNF20 Suppresses Tumorigenesis by Inhibiting SREBP1c-PTTG1 Axis in Kidney Cancer.

Mol Cell Biol 2017 Aug 21. Epub 2017 Aug 21.

National Creative Research Initiatives Center for Adipose Tissue Remodeling, Institute of Molecular Biology and Genetics, Department of Biological Sciences, Seoul National University

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August 2017

MGMT promoter methylation status as a prognostic factor for the outcome of gamma knife radiosurgery for recurrent glioblastoma.

J Neurooncol 2017 Jul 23;133(3):615-622. Epub 2017 May 23.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

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July 2017

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.

Cancer Cell 2017 07;32(1):42-56.e6

Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. Electronic address:

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July 2017

High-Throughput Clonogenic Analysis of 3D-Cultured Patient-Derived Cells with a Micropillar and Microwell Chip.

SLAS Discov 2017 Jun 21;22(5):645-651. Epub 2017 Feb 21.

5 Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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June 2017

Gamma knife radiosurgery for residual or recurrent intracranial hemangiopericytomas.

J Clin Neurosci 2017 Jan 18;35:35-41. Epub 2016 Oct 18.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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January 2017

Genomic and transcriptomic characterization of skull base chordoma.

Oncotarget 2017 Jan;8(1):1321-1328

Graduate School of Health Science & Technology, Samsung Advanced Institute for Health Science & Technology (SAIHST), Sungkyunkwan University, Seoul, Korea.

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January 2017

MicroRNA-1908-5p contributes to the oncogenic function of the splicing factor SRSF3.

Oncotarget 2017 Jan;8(5):8342-8355

Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea.

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January 2017

The Influence of Biomarker Mutations and Systemic Treatment on Cerebral Metastases from NSCLC Treated with Radiosurgery.

J Korean Neurosurg Soc 2017 Jan 29;60(1):21-29. Epub 2016 Dec 29.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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January 2017

Analysis of risk factors to predict communicating hydrocephalus following gamma knife radiosurgery for intracranial schwannoma.

Cancer Med 2016 12 23;5(12):3615-3621. Epub 2016 Nov 23.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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December 2016

Outcomes of Gamma Knife Radiosurgery in Combination with Crizotinib for Patients with Brain Metastasis from Non-Small Cell Lung Cancer.

World Neurosurg 2016 Nov 24;95:399-405. Epub 2016 Aug 24.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Republic of Korea. Electronic address:

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November 2016

Clinical outcome of neurofibromatosis type 2-related vestibular schwannoma: treatment strategies and challenges.

Neurosurg Rev 2016 Oct 4;39(4):643-53. Epub 2016 May 4.

Department of Otolaryngology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.

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October 2016

Therapeutic Strategy for Cavernous Sinus-Invading Non-Functioning Pituitary Adenomas Based on the Modified Knosp Grading System.

Brain Tumor Res Treat 2016 Oct 31;4(2):63-69. Epub 2016 Oct 31.

Department of Neurosurgery, Endoscopic Skull Base Surgery Clinic, Brain Tumor Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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October 2016

Clinical and Radiological Characteristics of Angiomatous Meningiomas.

Brain Tumor Res Treat 2016 Oct 31;4(2):94-99. Epub 2016 Oct 31.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Korea.

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October 2016

Nasoseptal Flap Elevation in Patients with History of Septal Surgery: Does It Increase Flap Failure or Cerebrospinal Fluid Leakage?

World Neurosurg 2016 Sep 11;93:164-7. Epub 2016 Jun 11.

Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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September 2016

Integrative radiogenomic analysis for genomic signatures in glioblastomas presenting leptomeningeal dissemination.

Medicine (Baltimore) 2016 Jul;95(27):e4109

aDepartment of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Korea bDepartments of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea cSamsung Biomedical Research Institute, Samsung Medical Center, Seoul, Korea dInstitute for Refractory Cancer Research, Samsung Medical Center, Seoul, Korea eSamsung Advanced Institute of Technology, Samsung Electronics Co. Ltd., Seoul, Korea fDepartment of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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July 2016

FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2.

PLoS One 2015 7;10(10):e0137703. Epub 2015 Oct 7.

Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea; Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

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June 2016

Serial Re-Expansion of Pituitary Gland Is Associated with Endocrinologic Recovery.

World Neurosurg 2016 Jun 26;90:496-503. Epub 2016 Mar 26.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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June 2016

Functional Outcome of the Facial Nerve After Surgery for Vestibular Schwannoma: Prediction of Acceptable Long-Term Facial Nerve Function Based on Immediate Postoperative Facial Palsy.

World Neurosurg 2016 May 28;89:215-22. Epub 2016 Jan 28.

Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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May 2016

Gamma knife radiosurgery for trigeminal neuralgia secondary to benign lesions.

Headache 2016 May 4;56(5):883-889. Epub 2016 Apr 4.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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May 2016

Anti-miR delivery strategies to bypass the blood-brain barrier in glioblastoma therapy.

Oncotarget 2016 May;7(20):29400-11

Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Korea.

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May 2016

Clinical Concerns about Recurrence of Non-Functioning Pituitary Adenoma.

Brain Tumor Res Treat 2016 Apr 29;4(1):1-7. Epub 2016 Apr 29.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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April 2016

Facilitating tailored therapeutic strategies for glioblastoma through an orthotopic patient-derived xenograft platform.

Histol Histopathol 2016 Mar 18;31(3):269-83. Epub 2015 Nov 18.

Institute for Refractory Cancer Research, Samsung Medical Center, Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University and Departments of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

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March 2016

Novel Morphologic and Genetic Analysis of Cancer Cells in a 3D Microenvironment Identifies STAT3 as a Regulator of Tumor Permeability Barrier Function.

Cancer Res 2016 Mar 16;76(5):1044-54. Epub 2015 Dec 16.

Medicinal Bioconvergence Research Center, Seoul National University, Seoul, Korea. Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Technology, College of Pharmacy, Seoul National University, Seoul, Korea. The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

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March 2016

Endoscopic Modified Transseptal Transsphenoidal Approach for Maximal Preservation of Sinonasal Quality of Life and Olfaction.

World Neurosurg 2016 Mar 28;87:162-9. Epub 2015 Dec 28.

Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. Electronic address:

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March 2016

Involvement of DDX6 gene in radio- and chemoresistance in glioblastoma.

Int J Oncol 2016 Mar 11;48(3):1053-62. Epub 2016 Jan 11.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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March 2016

Integrative radiogenomic analysis for multicentric radiophenotype in glioblastoma.

Oncotarget 2016 Mar;7(10):11526-38

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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March 2016

WNT signaling in glioblastoma and therapeutic opportunities.

Lab Invest 2016 Feb 7;96(2):137-50. Epub 2015 Dec 7.

Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea.

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February 2016

Repurposing antipsychotics as glioblastoma therapeutics: Potentials and challenges.

Oncol Lett 2016 Feb 7;11(2):1281-1286. Epub 2016 Jan 7.

Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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February 2016

USP1 targeting impedes GBM growth by inhibiting stem cell maintenance and radioresistance.

Neuro Oncol 2016 Jan 1;18(1):37-47. Epub 2015 Jun 1.

Department of Neurosurgery, Samsung Medical Center and Samsung Biomedical Research Institute, Seoul, Korea (J.-K.L., Y.Y., H.Y., W.K., D.-H.N.); Graduate School of Health Science & Technology, Samsung Advanced Institute for Health Science & Technology, Sungkyunkwan University, Seoul, Korea (N.C., H.C., Y.T.O., Y.Y., D.-H.N.); Department of Anatomy and Cell Biology, Sungkyunkwan University School of Medicine, Seoul, Korea (K.M.J.); Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio (E.K., Y.S., G.I.M., J.L.).

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January 2016

Malignant Glioma with Neuronal Marker Expression : A Clinicopathological Study of 18 Cases.

J Korean Neurosurg Soc 2016 Jan 20;59(1):44-51. Epub 2016 Jan 20.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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January 2016

Effectiveness of Postoperative Gamma Knife Radiosurgery to the Tumor Bed After Resection of Brain Metastases.

World Neurosurg 2015 Dec 26;84(6):1752-7. Epub 2015 Jul 26.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Republic of Korea. Electronic address:

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December 2015

Natural killer (NK) cells inhibit systemic metastasis of glioblastoma cells and have therapeutic effects against glioblastomas in the brain.

BMC Cancer 2015 Dec 24;15:1011. Epub 2015 Dec 24.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-Dong, Gangnam-Gu, Seoul, 06351, South Korea.

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December 2015

Outcome of gamma knife radiosurgery for metastatic brain tumors derived from non-small cell lung cancer.

J Neurooncol 2015 11 15;125(2):331-8. Epub 2015 Sep 15.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro, Gangnam Gu, Seoul, 135-710, Korea.

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November 2015

Automatic 3D Cell Analysis in High-Throughput Microarray Using Micropillar and Microwell Chips.

J Biomol Screen 2015 Oct 3;20(9):1178-84. Epub 2015 Aug 3.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Korea.

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October 2015

A multicenter study of anaplastic oligodendroglioma: the Korean Radiation Oncology Group Study 13-12.

J Neurooncol 2015 10 4;125(1):207-15. Epub 2015 Sep 4.

Department of Radiation Oncology, Seoul National University College of Medicine, Seoul, Korea.

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October 2015

Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM).

Eur J Med Chem 2015 Oct 4;103:210-22. Epub 2015 Aug 4.

Chemical Kinomics Research Center, Korea Institute of Science and Technology (KIST), Seoul 136-791, South Korea; Department of Biological Chemistry, Korea University of Science and Technology (UST), Daejeon 305-350, South Korea. Electronic address:

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October 2015

Prognostic impact of molecular phenotype in patients with recurrent anaplastic glioma treated with prolonged administration of temozolomide.

J Clin Neurosci 2015 Sep 29;22(9):1425-9. Epub 2015 Jun 29.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong Kangnam-ku, Seoul 135-710, Republic of Korea. Electronic address:

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September 2015

Talin1 targeting potentiates anti-angiogenic therapy by attenuating invasion and stem-like features of glioblastoma multiforme.

Oncotarget 2015 Sep;6(29):27239-51

Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Korea.

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September 2015

Spatiotemporal Evolution of the Primary Glioblastoma Genome.

Cancer Cell 2015 Sep;28(3):318-28

Samsung Biomedical Research Institute, Samsung Medical Center, Seoul 06351, Korea; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Science and Technology (SAIHST), Sungkyunkwan University, Seoul 06351, Korea; Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea. Electronic address:

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September 2015

Prognostic implication of progression pattern after anti-VEGF bevacizumab treatment for recurrent malignant gliomas.

J Neurooncol 2015 Aug 31;124(1):101-10. Epub 2015 May 31.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 135-710, Korea.

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August 2015