Djamel Lebeche

Djamel Lebeche

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Djamel Lebeche

Djamel Lebeche

Publications by authors named "Djamel Lebeche"

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A role for calcium in resistin transcriptional activation in diabetic hearts.

Sci Rep 2018 10 23;8(1):15633. Epub 2018 Oct 23.

Cardiovascular Research Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, 10029, USA.

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http://www.nature.com/articles/s41598-018-34112-4
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http://dx.doi.org/10.1038/s41598-018-34112-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199245PMC
October 2018

SERCA control of cell death and survival.

Cell Calcium 2018 01 12;69:46-61. Epub 2017 Jul 12.

Cardiovascular Research Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Diabetes, Obesity and Metabolism Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Graduate School of Biological Sciences, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ceca.2017.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748262PMC
January 2018

HAX-1 regulates SERCA2a oxidation and degradation.

J Mol Cell Cardiol 2018 01 21;114:220-233. Epub 2017 Nov 21.

Department of Pharmacology and Systems Physiology, University of Cincinnati, College of Medicine, Cincinnati, OH, USA; Molecular Biology Division, Biomedical Research Foundation, Academy of Athens, Athens, Greece. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222828173034
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http://dx.doi.org/10.1016/j.yjmcc.2017.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801168PMC
January 2018

Empagliflozin Improves Left Ventricular Diastolic Dysfunction in a Genetic Model of Type 2 Diabetes.

Cardiovasc Drugs Ther 2017 Jun;31(3):233-246

Cardiovascular Research Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://dx.doi.org/10.1007/s10557-017-6734-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681671PMC
June 2017

SERCA2 Deficiency Impairs Pancreatic β-Cell Function in Response to Diet-Induced Obesity.

Diabetes 2016 10 3;65(10):3039-52. Epub 2016 Aug 3.

Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN Department of Medicine, Indiana University School of Medicine, Indianapolis, IN Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN Roudebush VA Medical Center, Indianapolis, IN

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http://dx.doi.org/10.2337/db16-0084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033263PMC
October 2016

The Probability of Inconstancy in Assessment of Cardiac Function Post-Myocardial Infarction in Mice.

Cardiovasc Pharm Open Access 2016 9;5(5). Epub 2016 Sep 9.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130155PMC
September 2016

Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders.

J Biol Chem 2016 Mar 23;291(10):5185-98. Epub 2015 Dec 23.

From the Cardiovascular Research Institute and Diabetes Obesity and Metabolism Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029,

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http://dx.doi.org/10.1074/jbc.M115.705012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777852PMC
March 2016

Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy.

Biochim Biophys Acta 2015 Nov 8;1853(11 Pt A):2870-84. Epub 2015 Aug 8.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2015.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715892PMC
November 2015

Diabetic cardiomyopathy: is resistin a culprit?

Authors:
Djamel Lebeche

Cardiovasc Diagn Ther 2015 Oct;5(5):387-93

Cardiovascular Research Institute, Graduate School of Biological Sciences, Department of Medicine, Division of Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://dx.doi.org/10.3978/j.issn.2223-3652.2015.05.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609909PMC
October 2015

Multifaceted roles of miR-1s in repressing the fetal gene program in the heart.

Cell Res 2014 Mar 31;24(3):278-92. Epub 2014 Jan 31.

Mindich Child Health and Development Institute, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1040, New York, NY 10029, USA.

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http://dx.doi.org/10.1038/cr.2014.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945888PMC
March 2014

Differential patterns of replacement and reactive fibrosis in pressure and volume overload are related to the propensity for ischaemia and involve resistin.

J Physiol 2013 Nov 9;591(21):5337-55. Epub 2013 Sep 9.

D. Lebeche: Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1030, New York, NY 10029, USA.

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http://dx.doi.org/10.1113/jphysiol.2013.258731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936371PMC
November 2013

Bone morphogenetic protein-2 decreases microRNA-30b and microRNA-30c to promote vascular smooth muscle cell calcification.

J Am Heart Assoc 2012 Dec 19;1(6):e003905. Epub 2012 Dec 19.

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1161/JAHA.112.003905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540659PMC
December 2012

Cyclosporine attenuates cardiomyocyte hypertrophy induced by RAF1 mutants in Noonan and LEOPARD syndromes.

J Mol Cell Cardiol 2011 Jul 8;51(1):4-15. Epub 2011 Apr 8.

Departments of Pediatrics and Genetics and Genomic Sciences and the Child Health and Development Institute, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2011.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103595PMC
July 2011

KChIP2 attenuates cardiac hypertrophy through regulation of Ito and intracellular calcium signaling.

J Mol Cell Cardiol 2010 Jun 4;48(6):1169-79. Epub 2010 Jan 4.

Cardiovascular Research Center, Mount Sinai School of Medicine, Atran Building AB5-10, One Gustave L. Levy Place, Box 1030, New York, NY 10029-6574, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2009.12.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866822PMC
June 2010

Diabetic cardiomyopathy: signaling defects and therapeutic approaches.

Expert Rev Cardiovasc Ther 2010 Mar;8(3):373-91

Cardiovascular Research Center, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1586/erc.10.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137585PMC
March 2010

Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy.

Nat Clin Pract Cardiovasc Med 2008 Nov 23;5(11):715-24. Epub 2008 Sep 23.

Cardiovascular Research Center, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://www.nature.com/articles/ncpcardio1347
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http://dx.doi.org/10.1038/ncpcardio1347DOI Listing
November 2008

Ventricular arrhythmias after left ventricular assist device implantation.

Pacing Clin Electrophysiol 2008 Oct;31(10):1246-52

Divisions of Cardiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1111/j.1540-8159.2008.01173.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752870PMC
October 2008

Role of resistin in cardiac contractility and hypertrophy.

J Mol Cell Cardiol 2008 Aug 20;45(2):270-80. Epub 2008 May 20.

Cardiovascular Research Center, Mount Sinai School of Medicine, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2008.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613017PMC
August 2008

Quantitation of CXCR4 expression in myocardial infarction using 99mTc-labeled SDF-1alpha.

J Nucl Med 2008 Jun 15;49(6):963-9. Epub 2008 May 15.

Division of Hematology/Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.2967/jnumed.107.050054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712574PMC
June 2008

Preservation of mechanical and energetic function after adenoviral gene transfer in normal rat hearts.

Clin Exp Pharmacol Physiol 2007 Dec;34(12):1300-6

Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.

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http://dx.doi.org/10.1111/j.1440-1681.2007.04742.xDOI Listing
December 2007

Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair.

Nat Med 2007 Aug 15;13(8):962-9. Epub 2007 Jul 15.

Department of Cardiology, Children's Hospital Boston, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nm1619DOI Listing
August 2007

Targeted gene transfer increases contractility and decreases oxygen cost of contractility in normal rat hearts.

Am J Physiol Heart Circ Physiol 2007 May 12;292(5):H2356-63. Epub 2007 Jan 12.

Mount Sinai School of Medicine, Atran Laboratory Building, One Gustave L. Levy Place, Box 1030, New York, NY 10029-6574, USA.

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http://dx.doi.org/10.1152/ajpheart.01310.2006DOI Listing
May 2007

Transcoronary gene transfer of SERCA2a increases coronary blood flow and decreases cardiomyocyte size in a type 2 diabetic rat model.

Am J Physiol Heart Circ Physiol 2007 Feb 29;292(2):H1204-7. Epub 2006 Sep 29.

Cardiovascular Research Center, Massachusetts General Hospital, 149 13th St., CNY-4, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1152/ajpheart.00892.2006DOI Listing
February 2007

Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer.

Mol Ther 2006 May 24;13(5):987-96. Epub 2006 Feb 24.

Cardiovascular Research Center, Cardiology Laboratory of Integrative Physiology & Imaging, Massachusetts General Hospital, 149 13th Street, CNY-4, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.ymthe.2006.01.002DOI Listing
May 2006

Modulation of action potential duration on myocyte hypertrophic pathways.

J Mol Cell Cardiol 2006 May;40(5):725-35

Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, 02129, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2006.01.018DOI Listing
May 2006

Transgenic models of heart failure: elucidation of the molecular mechanisms of heart disease.

Heart Fail Clin 2005 Jul;1(2):219-36

Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.hfc.2005.03.005DOI Listing
July 2005

In vivo gene transfer of parvalbumin improves diastolic function in aged rat hearts.

Cardiovasc Res 2005 May;66(2):318-23

Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.cardiores.2004.06.028DOI Listing
May 2005

In vivo cardiac gene transfer of Kv4.3 abrogates the hypertrophic response in rats after aortic stenosis.

Circulation 2004 Nov 22;110(22):3435-43. Epub 2004 Nov 22.

Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Mass 02129, USA.

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http://dx.doi.org/10.1161/01.CIR.0000148176.33730.3FDOI Listing
November 2004

Gene transfer of parvalbumin improves diastolic dysfunction in senescent myocytes.

Circulation 2004 Jun 1;109(22):2780-5. Epub 2004 Jun 1.

Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Mass 02129, USA.

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http://dx.doi.org/10.1161/01.CIR.0000131764.62242.96DOI Listing
June 2004

Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling.

Proc Natl Acad Sci U S A 2004 Apr 25;101(15):5622-7. Epub 2004 Mar 25.

Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1073/pnas.0305778101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC397450PMC
April 2004

Candesartan abrogates G protein-coupled receptors agonist-induced MAPK activation and cardiac myocyte hypertrophy.

J Renin Angiotensin Aldosterone Syst 2001 Mar;2(1_suppl):S154-S161

Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA, mgh.harvard.edu.

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http://dx.doi.org/10.1177/14703203010020012701DOI Listing
March 2001