Publications by authors named "Divya P Kumar"

24Publications

Etiology of Hepatocellular Carcinoma: Special Focus on Fatty Liver Disease.

Authors:
Diwakar Suresh Akshatha N Srinivas Divya P Kumar

Front Oncol 2020 30;10:601710. Epub 2020 Nov 30.

Department of Biochemistry, Center of Excellence in Molecular Biology and Regenerative Medicine (CEMR), Jagadguru Sri Shivarathreeshwara (JSS) Medical College, JSS Academy of Higher Education and Research, Mysuru, India.

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November 2020

Emerging roles of AATF: Checkpoint signaling and beyond.

Authors:
Akshatha N Srinivas Diwakar Suresh Faridoddin Mirshahi Prasanna K Santhekadur Arun J Sanyal Divya P Kumar

J Cell Physiol 2020 Nov 4. Epub 2020 Nov 4.

Department of Biochemistry, CEMR, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.

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November 2020

Identification of a metabolic, transcriptomic and molecular signature of PNPLA3-mediated acceleration of steatohepatitis.

Authors:
Bubu A Banini Divya P Kumar Sophie Cazanave Mulugeta Seneshaw Faridoddin Mirshahi Prasanna K Santhekadur Liangsu Wang Hong Ping Guan Abdul Oseini Cristina Alonso Pierre Bedossa Srinivas V Koduru Hae-Ki Min Arun J Sanyal

Hepatology 2020 Nov 1. Epub 2020 Nov 1.

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, VA, USA.

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November 2020

The PPAR α/γ Agonist Saroglitazar Improves Insulin Resistance and Steatohepatitis in a Diet Induced Animal Model of Nonalcoholic Fatty Liver Disease.

Authors:
Divya P Kumar Rebecca Caffrey Jonathon Marioneaux Prasanna K Santhekadur Madhavi Bhat Cristina Alonso Srinivas V Koduru Binu Philip Mukul R Jain Suresh R Giri Pierre Bedossa Arun J Sanyal

Sci Rep 2020 06 9;10(1):9330. Epub 2020 Jun 9.

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, Virginia, USA.

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June 2020

Author Correction: The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease.

Authors:
Sophie Cazanave Alexei Podtelezhnikov Kristian Jensen Mulugeta Seneshaw Divya P Kumar Hae-Ki Min Prasanna K Santhekadur Bubu Banini Adolfo Gabriele Mauro Abdul M Oseini Robert Vincent Keith Q Tanis Andrea L Webber Liangsu Wang Pierre Bedossa Faridoddin Mirshahi Arun J Sanyal

Sci Rep 2020 May 15;10(1):8374. Epub 2020 May 15.

Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA.

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May 2020

RISC assembly and post-transcriptional gene regulation in Hepatocellular Carcinoma.

Authors:
Prasanna K Santhekadur Divya P Kumar

Genes Dis 2020 Jun 17;7(2):199-204. Epub 2019 Sep 17.

Department of Biochemistry, Center of Excellence in Molecular Biology & Regenerative Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysore, India.

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June 2020

Inflammatory Mediators in Obesity.

Authors:
Divya P Kumar Saisudha Koka Chao Li Senthilkumar Rajagopal

Mediators Inflamm 2019 31;2019:9481819. Epub 2019 Jul 31.

Department of Biochemistry, Rayalaseema University, Kurnool, Andra Pradesh, India.

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June 2020

A Regulatory Role of Apoptosis Antagonizing Transcription Factor in the Pathogenesis of Nonalcoholic Fatty Liver Disease and Hepatocellular Carcinoma.

Authors:
Divya P Kumar Prasanna K Santhekadur Mulugeta Seneshaw Faridoddin Mirshahi Cora Uram-Tuculescu Arun J Sanyal

Hepatology 2019 04 4;69(4):1520-1534. Epub 2019 Mar 4.

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, VA.

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April 2019

The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease.

Authors:
Sophie Cazanave Alexei Podtelezhnikov Kristian Jensen Mulugeta Seneshaw Divya P Kumar Hae-Ki Min Prasanna K Santhekadur Bubu Banini Adolfo Gabriele Mauro Abdul M Oseini Robert Vincent Keith Q Tanis Andrea L Webber Liangsu Wang Pierre Bedossa Faridoddin Mirshahi Arun J Sanyal

Sci Rep 2017 12 8;7(1):17193. Epub 2017 Dec 8.

Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA.

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December 2017

Preclinical models of non-alcoholic fatty liver disease.

Authors:
Prasanna K Santhekadur Divya P Kumar Arun J Sanyal

J Hepatol 2018 02 9;68(2):230-237. Epub 2017 Nov 9.

Div. of Gastroenterology, Hepatology and Nutrition, Dept. of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, United States. Electronic address:

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February 2018

The circulating microbiome signature and inferred functional metagenomics in alcoholic hepatitis.

Authors:
Puneet Puri Suthat Liangpunsakul Jeffrey E Christensen Vijay H Shah Patrick S Kamath Gregory J Gores Susan Walker Megan Comerford Barry Katz Andrew Borst Qigui Yu Divya P Kumar Faridoddin Mirshahi Svetlana Radaeva Naga P Chalasani David W Crabb Arun J Sanyal

Hepatology 2018 04 22;67(4):1284-1302. Epub 2018 Feb 22.

Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Virginia Commonwealth University, Richmond, VA.

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April 2018

The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids.

Authors:
Puneet Puri Kalyani Daita Andrew Joyce Faridoddin Mirshahi Prasanna K Santhekadur Sophie Cazanave Velimir A Luketic Mohammad S Siddiqui Sherry Boyett Hae-Ki Min Divya P Kumar Rohit Kohli Huiping Zhou Phillip B Hylemon Melissa J Contos Michael Idowu Arun J Sanyal

Hepatology 2018 02 23;67(2):534-548. Epub 2017 Dec 23.

Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA.

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February 2018

The multifaceted role of natriuretic peptides in metabolic syndrome.

Authors:
Prasanna K Santhekadur Divya P Kumar Mulugeta Seneshaw Faridoddin Mirshahi Arun J Sanyal

Biomed Pharmacother 2017 Aug 7;92:826-835. Epub 2017 Jun 7.

McGuire Research Institute, McGuire Veterans Affairs Medical Center, Richmond, VA, USA; Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, VA, 23298, USA; Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, 23298, USA. Electronic address:

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August 2017

Activation of Transmembrane Bile Acid Receptor TGR5 Modulates Pancreatic Islet α Cells to Promote Glucose Homeostasis.

Authors:
Divya P Kumar Amon Asgharpour Faridoddin Mirshahi So Hyun Park Sichen Liu Yumi Imai Jerry L Nadler John R Grider Karnam S Murthy Arun J Sanyal

J Biol Chem 2016 Mar 12;291(13):6626-40. Epub 2016 Jan 12.

From the Departments of Internal Medicine and

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March 2016

Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation.

Authors:
Senthilkumar Rajagopal Ancy D Nalli Divya P Kumar Sayak Bhattacharya Wenhui Hu Sunila Mahavadi John R Grider Karnam S Murthy

J Pharmacol Exp Ther 2015 Mar 30;352(3):509-18. Epub 2014 Dec 30.

Department of Physiology and Biophysics, VCU Program in Enteric Neuromuscular Sciences, Virginia Commonwealth University, Richmond, Virginia

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March 2015

Release of GLP-1 and PYY in response to the activation of G protein-coupled bile acid receptor TGR5 is mediated by Epac/PLC-ε pathway and modulated by endogenous H2S.

Authors:
Vanitha Bala Senthilkumar Rajagopal Divya P Kumar Ancy D Nalli Sunila Mahavadi Arun J Sanyal John R Grider Karnam S Murthy

Front Physiol 2014 3;5:420. Epub 2014 Nov 3.

Department of Physiology, VCU Program in Enteric Neuromuscular Sciences, Virginia Commonwealth University Richmond, VA, USA.

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November 2014

Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle.

Authors:
Sunila Mahavadi Ancy D Nalli Divya P Kumar Wenhui Hu John F Kuemmerle John R Grider Karnam S Murthy

Am J Physiol Cell Physiol 2014 Aug 18;307(4):C402-11. Epub 2014 Jun 18.

Department of Physiology and Biophysics, Virginia Commonwealth University Program in Enteric Neuromuscular Sciences, Virginia Commonwealth University, Richmond, Virginia; and

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August 2014

Regulation of Gβγi-dependent PLC-β3 activity in smooth muscle: inhibitory phosphorylation of PLC-β3 by PKA and PKG and stimulatory phosphorylation of Gαi-GTPase-activating protein RGS2 by PKG.

Authors:
Ancy D Nalli Divya P Kumar Othman Al-Shboul Sunila Mahavadi John F Kuemmerle John R Grider Karnam S Murthy

Cell Biochem Biophys 2014 Nov;70(2):867-80

Department of Physiology, VCU Program in Enteric Neuromuscular Sciences, Virginia Commonwealth University, Richmond, VA, 23298-0711, USA.

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November 2014

Hypercontractility of intestinal longitudinal smooth muscle induced by cytokines is mediated by the nuclear factor-κB/AMP-activated kinase/myosin light chain kinase pathway.

Authors:
Ancy D Nalli Divya P Kumar Sunila Mahavadi Othman Al-Shboul Reem Alkahtani John F Kuemmerle John R Grider Karnam S Murthy

J Pharmacol Exp Ther 2014 Jul 25;350(1):89-98. Epub 2014 Apr 25.

Department of Physiology and Biophysics, Program in Enteric Neuromuscular Sciences, Virginia Commonwealth University, Richmond, Virginia

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July 2014

Jun kinase-induced overexpression of leukemia-associated Rho GEF (LARG) mediates sustained hypercontraction of longitudinal smooth muscle in inflammation.

Authors:
Othman Al-Shboul Ancy D Nalli Divya P Kumar Ruizhe Zhou Sunila Mahavadi John F Kuemmerle John R Grider Karnam S Murthy

Am J Physiol Cell Physiol 2014 Jun 16;306(12):C1129-41. Epub 2014 Apr 16.

Department of Physiology and Biophysics, VCU Program in Enteric Neuromuscular Sciences, Virginia Commonwealth University, Richmond, Virginia

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June 2014

Inhibition of Gαi activity by Gβγ is mediated by PI 3-kinase-γ- and cSrc-dependent tyrosine phosphorylation of Gαi and recruitment of RGS12.

Authors:
Jiean Huang Ancy D Nalli Sunila Mahavadi Divya P Kumar Karnam S Murthy

Am J Physiol Gastrointest Liver Physiol 2014 May 27;306(9):G802-10. Epub 2014 Feb 27.

Department of Physiology and Biophysics, Program in Enteric Neuromuscular Sciences, Virginia Commonwealth University, Richmond, Virginia.

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May 2014

Increased PDE5 activity and decreased Rho kinase and PKC activities in colonic muscle from caveolin-1-/- mice impair the peristaltic reflex and propulsion.

Authors:
Sunila Mahavadi Sayak Bhattacharya Divya P Kumar Chereena Clay Gracious Ross Hamid I Akbarali John R Grider Karnam S Murthy

Am J Physiol Gastrointest Liver Physiol 2013 Dec 24;305(12):G964-74. Epub 2013 Oct 24.

Box 980551, Dept. of Physiology, School of Medicine, Virginia Commonwealth Univ., Richmond, VA 23298-0551.

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December 2013

Activation of G protein-coupled bile acid receptor, TGR5, induces smooth muscle relaxation via both Epac- and PKA-mediated inhibition of RhoA/Rho kinase pathway.

Authors:
Senthilkumar Rajagopal Divya P Kumar Sunila Mahavadi Sayak Bhattacharya Ruizhe Zhou Carlos U Corvera Nigel W Bunnett John R Grider Karnam S Murthy

Am J Physiol Gastrointest Liver Physiol 2013 Mar 28;304(5):G527-35. Epub 2012 Dec 28.

Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA 23298-0551, USA.

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March 2013

Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic β cells.

Authors:
Divya P Kumar Senthilkumar Rajagopal Sunila Mahavadi Faridoddin Mirshahi John R Grider Karnam S Murthy Arun J Sanyal

Biochem Biophys Res Commun 2012 Oct 27;427(3):600-5. Epub 2012 Sep 27.

Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

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October 2012