Publications by authors named "Dirksen Bussiere"

28Publications

First Crystal Structure of a Nonstructural Hepatitis E Viral Protein Identifies a Putative Novel Zinc-Binding Protein.

J Virol 2019 07 14;93(13). Epub 2019 Jun 14.

Structural and Biophysical Chemistry Group, Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, California, USA

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July 2019

High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization.

J Am Chem Soc 2017 12 30;139(49):17824-17833. Epub 2017 Nov 30.

Global Discovery Chemistry, Novartis Institutes for BioMedical Research , 5300 Chiron Way, Emeryville, California 94608, United States.

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December 2017

Design and synthesis of benzoazepin-2-one analogs as allosteric binders targeting the PIF pocket of PDK1.

Bioorg Med Chem Lett 2010 Jul 12;20(13):3897-902. Epub 2010 May 12.

Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA.

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July 2010

The discovery of tetrahydro-beta-carbolines as inhibitors of the kinesin Eg5.

Bioorg Med Chem Lett 2010 Jan 12;20(1):157-60. Epub 2009 Nov 12.

Global Discovery Chemistry/Oncology and Exploratory Chemistry, Novartis Institutes for Biomedical Research, 5400 Hollis Street, Emeryville, CA 94608, USA.

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January 2010