Publications by authors named "Dirkje Postma"

100Publications

IL1RL1 gene variations are associated with asthma exacerbations in children and adolescents using inhaled corticosteroids.

Allergy 2020 04 17;75(4):984-989. Epub 2019 Dec 17.

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/all.14125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176513PMC
April 2020

Small airways dysfunction: is there any involvement in patients with atopy? - Authors' reply.

Lancet Respir Med 2019 09;7(9):e27

Department of Pulmonology, Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen 9713 GZ, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(19)30248-6DOI Listing
September 2019

Genetic risk scores do not improve asthma prediction in childhood.

J Allergy Clin Immunol 2019 09 27;144(3):857-860.e7. Epub 2019 May 27.

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.05.017DOI Listing
September 2019

Pathway analysis of a genome-wide gene by air pollution interaction study in asthmatic children.

J Expo Sci Environ Epidemiol 2019 06 26;29(4):539-547. Epub 2019 Apr 26.

Channing Division of Network Medicine, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.1038/s41370-019-0136-3DOI Listing
June 2019

Predictors of clinical response to extrafine and non-extrafine particle inhaled corticosteroids in smokers and ex-smokers with asthma.

Respir Res 2018 Dec 18;19(1):256. Epub 2018 Dec 18.

Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, PO Box 30.0001, 9700, RB, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/s12931-018-0961-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299530PMC
December 2018

microRNA-mRNA regulatory networks underlying chronic mucus hypersecretion in COPD.

Eur Respir J 2018 09 6;52(3). Epub 2018 Sep 6.

Dept of Pathology and Medical Biology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1183/13993003.01556-2017DOI Listing
September 2018

Predictive value of eosinophils and neutrophils on clinical effects of ICS in COPD.

Respirology 2018 11 26;23(11):1023-1031. Epub 2018 Apr 26.

Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/resp.13312DOI Listing
November 2018

Genetic regulation of methylation and IL1RL1-a protein levels in asthma.

Eur Respir J 2018 03 8;51(3). Epub 2018 Mar 8.

Dept of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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http://dx.doi.org/10.1183/13993003.01377-2017DOI Listing
March 2018

Occupational exposure to pesticides is associated with differential DNA methylation.

Occup Environ Med 2018 06 19;75(6):427-435. Epub 2018 Feb 19.

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1136/oemed-2017-104787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969365PMC
June 2018

SIRT1/FoxO3 axis alteration leads to aberrant immune responses in bronchial epithelial cells.

J Cell Mol Med 2018 04 7;22(4):2272-2282. Epub 2018 Feb 7.

Istituto di Biomedicina e Immunologia Molecolare-Consiglio Nazionale delle Ricerche, Palermo, Italy.

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http://dx.doi.org/10.1111/jcmm.13509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867095PMC
April 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Lung tissue gene-expression signature for the ageing lung in COPD.

Thorax 2017 Dec 6. Epub 2017 Dec 6.

University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, The Netherlands.

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http://dx.doi.org/10.1136/thoraxjnl-2017-210074DOI Listing
December 2017

Extrafine compared to non-extrafine particle inhaled corticosteroids in smokers and ex-smokers with asthma.

Respir Med 2017 Sep 8;130:35-42. Epub 2017 Jul 8.

University of Groningen, University Medical Centre Groningen, Department of Pulmonary Diseases, PO Box 30.0001, 9700 RB Groningen, The Netherlands; University of Groningen, University Medical Centre Groningen, Groningen Research Institute for Asthma and COPD, PO Box 30.0001, 9700 RB Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2017.07.005DOI Listing
September 2017

Targeting the small airways with dry powder adenosine: a challenging concept.

Eur Clin Respir J 2017 6;4(1):1369328. Epub 2017 Sep 6.

Department of Pulmonary Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1080/20018525.2017.1369328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642194PMC
September 2017

Extrafine Versus Fine Inhaled Corticosteroids in Relation to Asthma Control: A Systematic Review and Meta-Analysis of Observational Real-Life Studies.

J Allergy Clin Immunol Pract 2018 May - Jun;6(3):907-915.e7. Epub 2017 Sep 20.

Observational and Pragmatic Research Institute Pte Ltd, Singapore; Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2017.07.032DOI Listing
October 2019

Genetic and epigenetic regulation of YKL-40 in childhood.

J Allergy Clin Immunol 2018 03 21;141(3):1105-1114. Epub 2017 Jul 21.

Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Department of Pediatric Pulmonology and Pediatric Allergology, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2017.06.030DOI Listing
March 2018

Childhood factors associated with complete and clinical asthma remission at 25 and 49 years.

Eur Respir J 2017 06 8;49(6). Epub 2017 Jun 8.

University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands

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http://dx.doi.org/10.1183/13993003.01974-2016DOI Listing
June 2017

The effect of COPD severity and study duration on exacerbation outcome in randomized controlled trials.

Int J Chron Obstruct Pulmon Dis 2017 15;12:1457-1468. Epub 2017 May 15.

Department of Pulmonary Medicine and Tuberculosis, University Medical Center Groningen, GRIAC Research Institute, University of Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.2147/COPD.S130713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440002PMC
March 2018

miR-146a-5p plays an essential role in the aberrant epithelial-fibroblast cross-talk in COPD.

Eur Respir J 2017 05 25;49(5). Epub 2017 May 25.

Dept of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1183/13993003.02538-2016DOI Listing
May 2017

Pubertal Timing and Cardiometabolic Markers at Age 16 Years.

J Pediatr 2017 08 8;187:158-164. Epub 2017 May 8.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.jpeds.2017.04.008DOI Listing
August 2017

Sulfatase modifying factor 1 (SUMF1) is associated with Chronic Obstructive Pulmonary Disease.

Respir Res 2017 05 2;18(1):77. Epub 2017 May 2.

Respiratory Medicine and Allergology, Department of Clinical Sciences Lund, BMC, D12, Lund University, Skåne University Hospital, 221 84, Lund, Sweden.

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http://dx.doi.org/10.1186/s12931-017-0562-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414362PMC
May 2017

Sex-Related Allergic Rhinitis Prevalence Switch from Childhood to Adulthood: A Systematic Review and Meta-Analysis.

Int Arch Allergy Immunol 2017 29;172(4):224-235. Epub 2017 Apr 29.

ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.

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http://dx.doi.org/10.1159/000464324DOI Listing
August 2017

Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study.

Eur J Hum Genet 2017 06 12;25(7):877-885. Epub 2017 Apr 12.

Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1038/ejhg.2017.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520063PMC
June 2017

Control of moderate-to-severe asthma with randomized ciclesonide doses of 160, 320 and 640 μg/day.

J Asthma Allergy 2017 7;10:35-46. Epub 2017 Mar 7.

Department of Pulmonology, Griac Research Institute, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.2147/JAA.S111712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349703PMC
March 2017

Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes.

J Allergy Clin Immunol 2017 02;139(2):388-399

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2016.12.940DOI Listing
February 2017

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

Nat Genet 2017 Mar 6;49(3):426-432. Epub 2017 Feb 6.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381275PMC
March 2017

Airway wall thickness on HRCT scans decreases with age and increases with smoking.

BMC Pulm Med 2017 02 1;17(1):27. Epub 2017 Feb 1.

Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/s12890-017-0363-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286807PMC
February 2017

Real-Life Outcomes for Patients with Asthma Prescribed Spacers for Use with Either Extrafine- or Fine-Particle Inhaled Corticosteroids.

J Allergy Clin Immunol Pract 2017 Jul - Aug;5(4):1040-1049.e4. Epub 2017 Jan 18.

Observational and Pragmatic Research Institute Pte Ltd, Singapore; Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132198163058
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http://dx.doi.org/10.1016/j.jaip.2016.11.026DOI Listing
January 2018

Early efficacy of budesonide/formoterol in patients with moderate-to-very-severe COPD.

Int J Chron Obstruct Pulmon Dis 2017 19;12:13-25. Epub 2016 Dec 19.

Department of Pulmonary Medicine and Tuberculosis, GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

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https://www.dovepress.com/early--efficacy-of-budesonideformo
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http://dx.doi.org/10.2147/COPD.S114209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182036PMC
August 2017

Identifying Risk of Future Asthma Attacks Using UK Medical Record Data: A Respiratory Effectiveness Group Initiative.

J Allergy Clin Immunol Pract 2017 Jul - Aug;5(4):1015-1024.e8. Epub 2016 Dec 22.

Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom; NIHR Southampton Respiratory Biomedical Research Unit, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jaip.2016.11.007DOI Listing
January 2018

Human asthma is characterized by more IRF5+ M1 and CD206+ M2 macrophages and less IL-10+ M2-like macrophages around airways compared with healthy airways.

J Allergy Clin Immunol 2017 07 19;140(1):280-283.e3. Epub 2016 Dec 19.

Department of Pharmacokinetics, Toxicology, and Targeting, Groningen Research Institute for Pharmacy, University of Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.11.020DOI Listing
July 2017

The Well-Known Gene HHIP and Novel Gene MECR Are Implicated in Small Airway Obstruction.

Am J Respir Crit Care Med 2016 11;194(10):1299-1302

1 University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC) Groningen, the Netherlands.

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http://dx.doi.org/10.1164/rccm.201604-0843LEDOI Listing
November 2016

TRPA1 gene polymorphisms and childhood asthma.

Pediatr Allergy Immunol 2017 03 8;28(2):191-198. Epub 2016 Dec 8.

Centre for Primary Care and Public Health, Barts and The London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1111/pai.12673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324656PMC
March 2017

Novel Genetic Susceptibility Loci for FEV1 in the Context of Occupational Exposure in Never-Smokers.

Am J Respir Crit Care Med 2016 09;194(6):769-72

1 University of Groningen, University Medical Center Groningen Groningen, the Netherlands.

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http://dx.doi.org/10.1164/rccm.201603-0646LEDOI Listing
September 2016

Genome-wide association study on the FEV/FVC ratio in never-smokers identifies HHIP and FAM13A.

J Allergy Clin Immunol 2017 02 6;139(2):533-540. Epub 2016 Sep 6.

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.06.062DOI Listing
February 2017

Air pollution exposure is associated with restrictive ventilatory patterns.

Eur Respir J 2016 10 4;48(4):1221-1224. Epub 2016 Aug 4.

Dept of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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http://dx.doi.org/10.1183/13993003.00556-2016DOI Listing
October 2016

Individualized prediction of lung-function decline in chronic obstructive pulmonary disease.

CMAJ 2016 Oct 2;188(14):1004-1011. Epub 2016 Aug 2.

Centre for Clinical Epidemiology and Evaluation (Zafari, Bryan, Sadatsafavi), Vancouver Coastal Health Research Institute, University of British Columbia; Centre for Heart and Lung Innovation (Sin, Man, McManus, Hollander), St. Paul's Hospital; Institute for Heart and Lung Health (Sin, Man, McManus, Hollander, Sadatsafavi), University of British Columbia; Division of Respiratory Medicine (Sin, Lam, Man, Sadatsafavi), Department of Medicine, University of British Columbia, Vancouver, BC; University Medical Center Groningen (Postma, Vonk), Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, Groningen; University Medical Center Groningen (Postma), Department of Pulmonary Diseases, University of Groningen, Groningen, the Netherlands; Department of Respiratory Medicine and Allergology (Löfdahl), Lund University, Lund, Sweden; Department of Epidemiology (Vonk), University of Groningen, University Medical Center Groningen, the Netherlands; School of Population and Public Health (Bryan), University of British Columbia, Vancouver, BC; Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences (Khakban), University of British Columbia, Vancouver, BC; David Geffen School of Medicine at UCLA (Tashkin), Los Angeles, Calif.; Johns Hopkins University School of Medicine (Wise), Baltimore, Md.; University of Minnesota School of Public Health (Connett), Minneapolis, Minn.; PROOF Centre for Excellence (McManus, Ng, Hollander), Vancouver, BC; Department of Community Health Sciences (Tammemagi), Brock University, St. Catharines, Ont.

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http://dx.doi.org/10.1503/cmaj.151483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047815PMC
October 2016

Interleukin-1α drives the dysfunctional cross-talk of the airway epithelium and lung fibroblasts in COPD.

Eur Respir J 2016 08 13;48(2):359-69. Epub 2016 Jul 13.

University of Groningen, University Medical Center Groningen, Dept of Pathology and Medical Biology, Groningen, The Netherlands University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The Netherlands University of Groningen, University Medical Center Groningen, Dept of Pulmonology, Groningen, The Netherlands These two authors contributed equally to this work.

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http://dx.doi.org/10.1183/13993003.01911-2015DOI Listing
August 2016

Airway hyperresponsiveness in chronic obstructive pulmonary disease: A marker of asthma-chronic obstructive pulmonary disease overlap syndrome?

J Allergy Clin Immunol 2016 12 24;138(6):1571-1579.e10. Epub 2016 May 24.

UBC James Hogg Research Center & the Institute for Heart and Lung Health, St Paul's Hospital, Vancouver, British Columbia, Canada; Department of Medicine (Pulmonary Division), University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.04.022DOI Listing
December 2016

The Dutch National Program for Respiratory Research.

Lancet Respir Med 2016 05;4(5):356-7

University of Groningen, Department of Respiratory Medicine, Amsterdam, Academic Medical Centre, University of Amsterdam, Netherlands.

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http://dx.doi.org/10.1016/S2213-2600(16)30035-2DOI Listing
May 2016

Susceptibility genes for lung diseases in the major histocompatibility complex revealed by lung expression quantitative trait loci analysis.

Eur Respir J 2016 08 12;48(2):573-6. Epub 2016 May 12.

Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada Dept of Molecular Medicine, Laval University, Québec, QC, Canada

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http://dx.doi.org/10.1183/13993003.00114-2016DOI Listing
August 2016

Cigarette smoke-induced epithelial expression of WNT-5B: implications for COPD.

Eur Respir J 2016 08 28;48(2):504-15. Epub 2016 Apr 28.

University of Groningen, University Medical Center Groningen, Dept of Pulmonology, Groningen, The Netherlands University of Groningen, University Medical Center Groningen GRIAC Research Institute, Groningen, The Netherlands.

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http://dx.doi.org/10.1183/13993003.01541-2015DOI Listing
August 2016

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.

Authors:
Bonnie R Joubert Janine F Felix Paul Yousefi Kelly M Bakulski Allan C Just Carrie Breton Sarah E Reese Christina A Markunas Rebecca C Richmond Cheng-Jian Xu Leanne K Küpers Sam S Oh Cathrine Hoyo Olena Gruzieva Cilla Söderhäll Lucas A Salas Nour Baïz Hongmei Zhang Johanna Lepeule Carlos Ruiz Symen Ligthart Tianyuan Wang Jack A Taylor Liesbeth Duijts Gemma C Sharp Soesma A Jankipersadsing Roy M Nilsen Ahmad Vaez M Daniele Fallin Donglei Hu Augusto A Litonjua Bernard F Fuemmeler Karen Huen Juha Kere Inger Kull Monica Cheng Munthe-Kaas Ulrike Gehring Mariona Bustamante Marie José Saurel-Coubizolles Bilal M Quraishi Jie Ren Jörg Tost Juan R Gonzalez Marjolein J Peters Siri E Håberg Zongli Xu Joyce B van Meurs Tom R Gaunt Marjan Kerkhof Eva Corpeleijn Andrew P Feinberg Celeste Eng Andrea A Baccarelli Sara E Benjamin Neelon Asa Bradman Simon Kebede Merid Anna Bergström Zdenko Herceg Hector Hernandez-Vargas Bert Brunekreef Mariona Pinart Barbara Heude Susan Ewart Jin Yao Nathanaël Lemonnier Oscar H Franco Michael C Wu Albert Hofman Wendy McArdle Pieter Van der Vlies Fahimeh Falahi Matthew W Gillman Lisa F Barcellos Ashish Kumar Magnus Wickman Stefano Guerra Marie-Aline Charles John Holloway Charles Auffray Henning W Tiemeier George Davey Smith Dirkje Postma Marie-France Hivert Brenda Eskenazi Martine Vrijheid Hasan Arshad Josep M Antó Abbas Dehghan Wilfried Karmaus Isabella Annesi-Maesano Jordi Sunyer Akram Ghantous Göran Pershagen Nina Holland Susan K Murphy Dawn L DeMeo Esteban G Burchard Christine Ladd-Acosta Harold Snieder Wenche Nystad Gerard H Koppelman Caroline L Relton Vincent W V Jaddoe Allen Wilcox Erik Melén Stephanie J London

Am J Hum Genet 2016 Apr 31;98(4):680-96. Epub 2016 Mar 31.

National Institute of Environmental Health Sciences, NIH, U.S. Department of Health and Human Services, Research Triangle Park, NC 27709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833289PMC
April 2016

Reply.

J Allergy Clin Immunol Pract 2016 Mar-Apr;4(2):372-3

Research in Real Life, Ltd, Cambridge, United Kingdom; Academic Primary Care, University of Aberdeen, Aberdeen, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2015.12.006DOI Listing
July 2016

Fibulin-5 as a potential therapeutic target in COPD.

Expert Opin Ther Targets 2016 09 25;20(9):1031-3. Epub 2016 Mar 25.

a Department of Pathology and Medical Biology , University of Groningen, University Medical Center Groningen , Groningen , The Netherlands.

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http://dx.doi.org/10.1517/14728222.2016.1164696DOI Listing
September 2016

Early response to inhaled bronchodilators and corticosteroids as a predictor of 12-month treatment responder status and COPD exacerbations.

Int J Chron Obstruct Pulmon Dis 2016 25;11:381-90. Epub 2016 Feb 25.

George Institute for Global Health, Concord Clincal School, The University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.2147/COPD.S93303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772946PMC
October 2016

TGF-β-induced profibrotic signaling is regulated in part by the WNT receptor Frizzled-8.

FASEB J 2016 05 5;30(5):1823-35. Epub 2016 Feb 5.

Comprehensive Pneumology Center, Helmholtz Center Munich, German Center for Lung Research (DZL), University Hospital Grosshadern, Ludwig Maximilians University Munich, Munich, Germany;

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http://dx.doi.org/10.1096/fj.201500129DOI Listing
May 2016

A pro-inflammatory role for the Frizzled-8 receptor in chronic bronchitis.

Thorax 2016 Apr 21;71(4):312-22. Epub 2016 Jan 21.

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1136/thoraxjnl-2015-206958DOI Listing
April 2016

Sexual maturation protects against development of lung inflammation through estrogen.

Am J Physiol Lung Cell Mol Physiol 2016 Jan 25;310(2):L166-74. Epub 2015 Nov 25.

University of Groningen, Department of Pharmacokinetics, Toxicology, and Targeting, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands;

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http://dx.doi.org/10.1152/ajplung.00119.2015DOI Listing
January 2016

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.

Authors:
Janine F Felix Jonathan P Bradfield Claire Monnereau Ralf J P van der Valk Evie Stergiakouli Alessandra Chesi Romy Gaillard Bjarke Feenstra Elisabeth Thiering Eskil Kreiner-Møller Anubha Mahajan Niina Pitkänen Raimo Joro Alana Cavadino Ville Huikari Steve Franks Maria M Groen-Blokhuis Diana L Cousminer Julie A Marsh Terho Lehtimäki John A Curtin Jesus Vioque Tarunveer S Ahluwalia Ronny Myhre Thomas S Price Natalia Vilor-Tejedor Loïc Yengo Niels Grarup Ioanna Ntalla Wei Ang Mustafa Atalay Hans Bisgaard Alexandra I Blakemore Amelie Bonnefond Lisbeth Carstensen Johan Eriksson Claudia Flexeder Lude Franke Frank Geller Mandy Geserick Anna-Liisa Hartikainen Claire M A Haworth Joel N Hirschhorn Albert Hofman Jens-Christian Holm Momoko Horikoshi Jouke Jan Hottenga Jinyan Huang Haja N Kadarmideen Mika Kähönen Wieland Kiess Hanna-Maaria Lakka Timo A Lakka Alexandra M Lewin Liming Liang Leo-Pekka Lyytikäinen Baoshan Ma Per Magnus Shana E McCormack George McMahon Frank D Mentch Christel M Middeldorp Clare S Murray Katja Pahkala Tune H Pers Roland Pfäffle Dirkje S Postma Christine Power Angela Simpson Verena Sengpiel Carla M T Tiesler Maties Torrent André G Uitterlinden Joyce B van Meurs Rebecca Vinding Johannes Waage Jane Wardle Eleftheria Zeggini Babette S Zemel George V Dedoussis Oluf Pedersen Philippe Froguel Jordi Sunyer Robert Plomin Bo Jacobsson Torben Hansen Juan R Gonzalez Adnan Custovic Olli T Raitakari Craig E Pennell Elisabeth Widén Dorret I Boomsma Gerard H Koppelman Sylvain Sebert Marjo-Riitta Järvelin Elina Hyppönen Mark I McCarthy Virpi Lindi Niinikoski Harri Antje Körner Klaus Bønnelykke Joachim Heinrich Mads Melbye Fernando Rivadeneira Hakon Hakonarson Susan M Ring George Davey Smith Thorkild I A Sørensen Nicholas J Timpson Struan F A Grant Vincent W V Jaddoe

Hum Mol Genet 2016 Jan 24;25(2):389-403. Epub 2015 Nov 24.

The Generation R Study Group, Department of Pediatrics, Department of Epidemiology.

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http://hmg.oxfordjournals.org/content/early/2015/12/16/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854022PMC
January 2016

Meta-analysis identifies seven susceptibility loci involved in the atopic march.

Nat Commun 2015 Nov 6;6:8804. Epub 2015 Nov 6.

Max-Delbrück-Center (MDC) for Molecular Medicine, Berlin, Germany.

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http://dx.doi.org/10.1038/ncomms9804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667629PMC
November 2015

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Johannes Waage Hansjörg Baurecht Melanie Hotze David P Strachan John A Curtin Klaus Bønnelykke Chao Tian Atsushi Takahashi Jorge Esparza-Gordillo Alexessander Couto Alves Jacob P Thyssen Herman T den Dekker Manuel A Ferreira Elisabeth Altmaier Patrick Ma Sleiman Feng Li Xiao Juan R Gonzalez Ingo Marenholz Birgit Kalb Maria Pino Yanes Cheng-Jian Xu Lisbeth Carstensen Maria M Groen-Blokhuis Cristina Venturini Craig E Pennell Sheila J Barton Albert M Levin Ivan Curjuric Mariona Bustamante Eskil Kreiner-Møller Gabrielle A Lockett Jonas Bacelis Supinda Bunyavanich Rachel A Myers Anja Matanovic Ashish Kumar Joyce Y Tung Tomomitsu Hirota Michiaki Kubo Wendy L McArdle A J Henderson John P Kemp Jie Zheng George Davey Smith Franz Rüschendorf Anja Bauerfeind Min Ae Lee-Kirsch Andreas Arnold Georg Homuth Carsten O Schmidt Elisabeth Mangold Sven Cichon Thomas Keil Elke Rodríguez Annette Peters Andre Franke Wolfgang Lieb Natalija Novak Regina Fölster-Holst Momoko Horikoshi Juha Pekkanen Sylvain Sebert Lise L Husemoen Niels Grarup Johan C de Jongste Fernando Rivadeneira Albert Hofman Vincent Wv Jaddoe Suzanne Gma Pasmans Niels J Elbert André G Uitterlinden Guy B Marks Philip J Thompson Melanie C Matheson Colin F Robertson Janina S Ried Jin Li Xian Bo Zuo Xiao Dong Zheng Xian Yong Yin Liang Dan Sun Maeve A McAleer Grainne M O'Regan Caoimhe Mr Fahy Linda E Campbell Milan Macek Michael Kurek Donglei Hu Celeste Eng Dirkje S Postma Bjarke Feenstra Frank Geller Jouke Jan Hottenga Christel M Middeldorp Pirro Hysi Veronique Bataille Tim Spector Carla Mt Tiesler Elisabeth Thiering Badri Pahukasahasram James J Yang Medea Imboden Scott Huntsman Natàlia Vilor-Tejedor Caroline L Relton Ronny Myhre Wenche Nystad Adnan Custovic Scott T Weiss Deborah A Meyers Cilla Söderhäll Erik Melén Carole Ober Benjamin A Raby Angela Simpson Bo Jacobsson John W Holloway Hans Bisgaard Jordi Sunyer Nicole M Probst Hensch L Keoki Williams Keith M Godfrey Carol A Wang Dorret I Boomsma Mads Melbye Gerard H Koppelman Deborah Jarvis Wh Irwin McLean Alan D Irvine Xue Jun Zhang Hakon Hakonarson Christian Gieger Esteban G Burchard Nicholas G Martin Liesbeth Duijts Allan Linneberg Marjo-Riitta Jarvelin Markus M Noethen Susanne Lau Norbert Hübner Young-Ae Lee Mayumi Tamari David A Hinds Daniel Glass Sara J Brown Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2015 Dec 19;47(12):1449-1456. Epub 2015 Oct 19.

Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.3424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753676PMC
December 2015