Publications by authors named "Dirk Trauner"

100Publications

Photolipid Bilayer Permeability is Controlled by Transient Pore Formation.

Langmuir 2020 11 3;36(45):13509-13515. Epub 2020 Nov 3.

Chair for Photonics and Optoelectronics, Nano-Institute Munich, Department of Physics, Ludwig-Maximilians-Universität (LMU), Königinstraße 10, 80539 Munich, Germany.

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http://dx.doi.org/10.1021/acs.langmuir.0c02229DOI Listing
November 2020

Metabolic tuning of inhibition regulates hippocampal neurogenesis in the adult brain.

Proc Natl Acad Sci U S A 2020 10 24;117(41):25818-25829. Epub 2020 Sep 24.

Department of Neurobiology & Behavior, State University of New York at Stony Brook, Stony Brook, NY 11794;

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http://dx.doi.org/10.1073/pnas.2006138117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568294PMC
October 2020

Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor γ (PPARγ).

J Med Chem 2020 Oct 21;63(19):10908-10920. Epub 2020 Sep 21.

Department of Chemistry, New York University, New York, New York 10003, United States.

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http://dx.doi.org/10.1021/acs.jmedchem.0c00654DOI Listing
October 2020

A Conversation with Gerhard Bringmann.

ACS Cent Sci 2020 Aug 6;6(8):1248-1252. Epub 2020 Aug 6.

Department of Chemistry, New York University, New York, New York 10003, United States.

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http://dx.doi.org/10.1021/acscentsci.0c00388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453420PMC
August 2020

Photoswitchable Lipids.

Chembiochem 2020 Aug 13. Epub 2020 Aug 13.

Department of Chemistry, New York University, 100 Washington Square East, New York, NY, 10003-6699, USA.

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http://dx.doi.org/10.1002/cbic.202000449DOI Listing
August 2020

Light-induced lipid mixing implies a causal role of lipid splay in membrane fusion.

Biochim Biophys Acta Biomembr 2020 Nov 8;1862(11):183438. Epub 2020 Aug 8.

Institute for Medical Physics and Biophysics, University of Leipzig, Härtelstr. 16-18, 04107 Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2020.183438DOI Listing
November 2020

Potential energy function for a photo-switchable lipid molecule.

J Comput Chem 2020 Oct 4;41(27):2336-2351. Epub 2020 Aug 4.

Department of Physics, Theoretical Molecular Biophysics Group, Freie Universität Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/jcc.26387DOI Listing
October 2020

Optical Control of Lysophosphatidic Acid Signaling.

J Am Chem Soc 2020 Jun 5;142(24):10612-10616. Epub 2020 Jun 5.

Department of Chemistry, New York University, New York, New York 10003, United States.

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http://dx.doi.org/10.1021/jacs.0c02154DOI Listing
June 2020

Photopharmacological control of lipid function.

Methods Enzymol 2020 27;638:219-232. Epub 2020 Apr 27.

Department of Chemistry, New York University, New York, NY, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2020.04.025DOI Listing
April 2020

Optical Manipulation of F-Actin with Photoswitchable Small Molecules.

J Am Chem Soc 2020 May 11;142(20):9240-9249. Epub 2020 May 11.

Institute for Organic Chemistry and Macromolecular Chemistry, Friedrich-Schiller-University, Humboldtstrasse 10, Jena D-07743, Germany.

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http://dx.doi.org/10.1021/jacs.9b12898DOI Listing
May 2020

A Photoswitchable Inhibitor of the Human Serotonin Transporter.

ACS Chem Neurosci 2020 05 23;11(9):1231-1237. Epub 2020 Apr 23.

Department of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, United States.

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http://dx.doi.org/10.1021/acschemneuro.9b00521DOI Listing
May 2020

Computational Design and Synthesis of a Deeply Red-Shifted and Bistable Azobenzene.

J Am Chem Soc 2020 04 24;142(14):6538-6547. Epub 2020 Mar 24.

Department of Pharmacy, Ludwig-Maximilians-University Munich, Butenandtstraße 5-13, Munich 81377, Germany.

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http://dx.doi.org/10.1021/jacs.9b10430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307923PMC
April 2020

Optical control of the nuclear bile acid receptor FXR with a photohormone.

Chem Sci 2020 Jan 19;11(2):429-434. Epub 2019 Nov 19.

Department of Chemistry , New York University , New York , New York 10003 , USA . Email:

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http://dx.doi.org/10.1039/c9sc02911gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067245PMC
January 2020

PHOTACs enable optical control of protein degradation.

Sci Adv 2020 02 21;6(8):eaay5064. Epub 2020 Feb 21.

Department of Chemistry, New York University, New York, NY 10003, USA.

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http://dx.doi.org/10.1126/sciadv.aay5064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034999PMC
February 2020

A Lipid Photoswitch Controls Fluidity in Supported Bilayer Membranes.

Langmuir 2020 03 3;36(10):2629-2634. Epub 2020 Mar 3.

Chair for Photonics and Optoelectronics, Nano-Institute Munich, Department of Physics, Ludwig-Maximilians-Universität München, Königinstrasse 10, 80539 Munich, Germany.

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http://dx.doi.org/10.1021/acs.langmuir.9b02942DOI Listing
March 2020

Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors.

Angew Chem Int Ed Engl 2020 04 4;59(17):6720-6723. Epub 2020 Mar 4.

Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 8204, Center for Infection and Immunity of Lille (CIIL), 59000, Lille, France.

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http://dx.doi.org/10.1002/anie.201915352DOI Listing
April 2020

Bioinspired Synthesis of (-)-PF-1018.

Angew Chem Int Ed Engl 2020 03 3;59(13):5263-5267. Epub 2020 Feb 3.

Department of Chemistry, New York University, 100 Washington Square East, New York, NY, 10003, USA.

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http://dx.doi.org/10.1002/anie.201912452DOI Listing
March 2020

Optical Control of Cytokine Production Using Photoswitchable Galactosylceramides.

Chemistry 2020 Apr 9;26(20):4476-4479. Epub 2020 Mar 9.

Department of Chemistry, New York University, 100 Washington Square East, New York, NY, 10003, USA.

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http://dx.doi.org/10.1002/chem.201905279DOI Listing
April 2020

Fixing a Photosensitizer Unlocks and Localizes Its Lethality.

ACS Cent Sci 2019 Oct 26;5(10):1636-1638. Epub 2019 Sep 26.

Department of Chemistry and Neuroscience Institute, New York University, New York City, New York 10002, United States.

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http://dx.doi.org/10.1021/acscentsci.9b00887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813549PMC
October 2019

Synthesis of acremines A, B and F and studies on the bisacremines.

Beilstein J Org Chem 2019 23;15:2271-2276. Epub 2019 Sep 23.

Department of Chemistry, University of Munich, Butenandtstraße 5-13, 81377 Munich, Germany.

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http://dx.doi.org/10.3762/bjoc.15.219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774081PMC
September 2019

Oxidative Approach Enables Efficient Access to Cyclic Azobenzenes.

J Am Chem Soc 2019 10 17;141(43):17295-17304. Epub 2019 Oct 17.

Department of Chemistry and Center for Integrated Protein Science (CIPSM) , Ludwig Maximilian University Munich , 81377 Munich , Germany.

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https://pubs.acs.org/doi/10.1021/jacs.9b08794
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http://dx.doi.org/10.1021/jacs.9b08794DOI Listing
October 2019

Photopharmacologic Vision Restoration Reduces Pathological Rhythmic Field Potentials in Blind Mouse Retina.

Sci Rep 2019 09 19;9(1):13561. Epub 2019 Sep 19.

Department of Ophthalmology, University of Washington School of Medicine, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/s41598-019-49999-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753071PMC
September 2019

A Biomimetic Synthesis Elucidates the Origin of Preuisolactone A.

J Am Chem Soc 2019 10 23;141(39):15515-15518. Epub 2019 Sep 23.

Department of Chemistry , New York University , Silver Center, 100 Washington Square East, Room 712 , New York , New York 10002 , United States.

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http://dx.doi.org/10.1021/jacs.9b08892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249536PMC
October 2019

Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers.

Angew Chem Int Ed Engl 2019 10 12;58(43):15421-15428. Epub 2019 Sep 12.

Department of Chemistry and Center for Integrated Protein Science (CIPSM), Ludwig Maximilian University Munich, Butenandtstr. 5-13, 81377, Munich, Germany.

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http://dx.doi.org/10.1002/anie.201905790DOI Listing
October 2019

Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor.

J Am Chem Soc 2019 07 10;141(29):11522-11530. Epub 2019 Jul 10.

Department of Molecular and Cell Biology , University of California , Berkeley , California 94720 , United States.

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http://dx.doi.org/10.1021/jacs.9b02895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271769PMC
July 2019

In honor of Professor Samuel J. Danishefsky.

J Antibiot (Tokyo) 2019 06 27;72(6):324. Epub 2019 May 27.

Department of Chemistry, New York University, New York, USA.

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http://dx.doi.org/10.1038/s41429-019-0182-zDOI Listing
June 2019

New players in phototherapy: photopharmacology and bio-integrated optoelectronics.

Curr Opin Chem Biol 2019 06 17;50:145-151. Epub 2019 May 17.

Department of Chemistry, New York University, 100 Washington Square East, New York, NY 10003-6699, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cbpa.2019.03.013DOI Listing
June 2019

Mapping the Azolog Space Enables the Optical Control of New Biological Targets.

ACS Cent Sci 2019 Apr 13;5(4):607-618. Epub 2019 Mar 13.

Department of Chemistry, New York University, 100 Washington Square East, New York, New York 10003-6699, United States.

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http://dx.doi.org/10.1021/acscentsci.8b00881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487453PMC
April 2019

Body Mass Index in Multiple Sclerosis modulates ceramide-induced DNA methylation and disease course.

EBioMedicine 2019 May 10;43:392-410. Epub 2019 Apr 10.

Department of Neuroscience, Icahn School of Medicine at Mount Sinai, NY, New York, United States of America; Advanced Science Research Center at The Graduate Center of The City University of New York and Inter-Institutional Center for Glial Biology at Icahn School of Medicine New York, New York, United States of America. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523964193023
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http://dx.doi.org/10.1016/j.ebiom.2019.03.087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557766PMC
May 2019

Synthesis and biological evaluation of (±)-hippolachnin and analogs.

J Antibiot (Tokyo) 2019 06 12;72(6):375-383. Epub 2019 Apr 12.

Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377, Munich, Germany.

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http://www.nature.com/articles/s41429-019-0176-x
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http://dx.doi.org/10.1038/s41429-019-0176-xDOI Listing
June 2019

Biomimetic Approach Toward Enterocin and Deoxyenterocin.

J Org Chem 2019 02 18;84(3):1162-1175. Epub 2019 Jan 18.

Department of Chemistry , Ludwig-Maximilians-Universität München , Butenandtstraße 5-13 , 81377 München , Germany.

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http://dx.doi.org/10.1021/acs.joc.8b02273DOI Listing
February 2019

Introduction: Optogenetics and Photopharmacology.

Chem Rev 2018 11;118(21):10627-10628

Department of Chemistry , New York University.

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http://pubs.acs.org/doi/10.1021/acs.chemrev.8b00483
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http://dx.doi.org/10.1021/acs.chemrev.8b00483DOI Listing
November 2018

Optical tools for understanding the complexity of β-cell signalling and insulin release.

Nat Rev Endocrinol 2018 12;14(12):721-737

Institute of Metabolism and Systems Research (IMSR) and Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham, Birmingham, UK.

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http://www.nature.com/articles/s41574-018-0105-2
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http://dx.doi.org/10.1038/s41574-018-0105-2DOI Listing
December 2018

Light-Controlled Lipid Interaction and Membrane Organization in Photolipid Bilayer Vesicles.

Langmuir 2018 11 22;34(44):13368-13374. Epub 2018 Oct 22.

Photonics and Optoelectronics Group, Department of Physics and CeNS , Ludwig-Maximilians-Universität München , Amalienstraße 54 , 80799 Munich , Germany.

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http://pubs.acs.org/doi/10.1021/acs.langmuir.8b03241
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http://dx.doi.org/10.1021/acs.langmuir.8b03241DOI Listing
November 2018

Biomimetic Synthesis of (+)-Aspergillin PZ.

Angew Chem Int Ed Engl 2018 11 2;57(47):15587-15591. Epub 2018 Nov 2.

Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, 81377, München, Germany.

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http://dx.doi.org/10.1002/anie.201809703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417427PMC
November 2018

A Versatile Bis-Allylboron Reagent for the Stereoselective Synthesis of Chiral Diols.

Angew Chem Int Ed Engl 2018 10 5;57(43):14276-14280. Epub 2018 Oct 5.

Department of Chemistry, New York University, 100 Washington Square East, New York, NY, 10003, USA.

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http://dx.doi.org/10.1002/anie.201808234DOI Listing
October 2018

SNAP-Tagged Nanobodies Enable Reversible Optical Control of a G Protein-Coupled Receptor via a Remotely Tethered Photoswitchable Ligand.

ACS Chem Biol 2018 09 7;13(9):2682-2688. Epub 2018 Sep 7.

Department of Chemical Biology , Max Planck Institute for Medical Research , Jahnstrasse 29 , 69120 Heidelberg , Germany.

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http://pubs.acs.org/doi/10.1021/acschembio.8b00628
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http://dx.doi.org/10.1021/acschembio.8b00628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620112PMC
September 2018

Optical control of L-type Ca channels using a diltiazem photoswitch.

Nat Chem Biol 2018 08 16;14(8):764-767. Epub 2018 Jul 16.

Department of Chemistry, University of Munich and Center for Integrated Protein Science (CIPSM), Munich, Germany.

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http://www.nature.com/articles/s41589-018-0090-8
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http://dx.doi.org/10.1038/s41589-018-0090-8DOI Listing
August 2018

Optical Control of a Delayed Rectifier and a Two-Pore Potassium Channel with a Photoswitchable Bupivacaine.

ACS Chem Neurosci 2018 12 14;9(12):2886-2891. Epub 2018 Aug 14.

Department of Chemistry and Center for Integrated Protein Science , LMU Munich , Butenandtstr. 5-13 , 81377 Munich , Germany.

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http://dx.doi.org/10.1021/acschemneuro.8b00279DOI Listing
December 2018

In Vivo Photopharmacology.

Chem Rev 2018 11 9;118(21):10710-10747. Epub 2018 Jul 9.

Department of Chemistry , New York University , 100 Washington Square East , New York , New York 10003-6699 , United States.

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http://pubs.acs.org/doi/10.1021/acs.chemrev.8b00037
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http://dx.doi.org/10.1021/acs.chemrev.8b00037DOI Listing
November 2018

Total Synthesis of (±)-Exotine B.

Org Lett 2018 07 6;20(14):4358-4361. Epub 2018 Jul 6.

Department of Chemistry , New York University , 100 Washington Square East , New York , New York 10003 , United States.

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http://dx.doi.org/10.1021/acs.orglett.8b01817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056846PMC
July 2018

Total Synthesis of the Norhasubanan Alkaloid Stephadiamine.

J Am Chem Soc 2018 07 9;140(28):8675-8680. Epub 2018 Jul 9.

Department of Chemistry , University of Munich , Butenandtstraße 5-13 , Munich 81377 , Germany.

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http://pubs.acs.org/doi/10.1021/jacs.8b01918
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http://dx.doi.org/10.1021/jacs.8b01918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130314PMC
July 2018

Optical control of GPR40 signalling in pancreatic β-cells.

Chem Sci 2017 Nov 30;8(11):7604-7610. Epub 2017 Aug 30.

Department of Chemistry , Center for Integrated Protein Science , Ludwig Maximilians University Munich , Butenandtstraße 5-13 , 81377 Munich , Germany.

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http://dx.doi.org/10.1039/c7sc01475aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848828PMC
November 2017

Toward (-)-Enterocin: An Improved Cuprate Barbier Protocol To Overcome Strain and Sterical Hindrance.

Org Lett 2018 04 19;20(7):1841-1844. Epub 2018 Mar 19.

Department of Chemistry and Center for Integrated Protein Science , Ludwig-Maximilians-Universitat München , Butenandtstrasse 5-13 , 81377 München , Germany.

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http://dx.doi.org/10.1021/acs.orglett.8b00353DOI Listing
April 2018

A (+)-Larixol Congener with High Affinity and Subtype Selectivity toward TRPC6.

ChemMedChem 2018 05 26;13(10):1028-1035. Epub 2018 Apr 26.

Rudolf Boehm Institute for Pharmacology and Toxicology, Leipzig University, Härtelstr. 16-18, 04107, Leipzig, Germany.

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http://doi.wiley.com/10.1002/cmdc.201800021
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http://dx.doi.org/10.1002/cmdc.201800021DOI Listing
May 2018

Azomethine Ylide Cycloaddition Approach toward Dendrobine: Synthesis of 5-Deoxymubironine C.

J Org Chem 2018 03 6;83(6):3061-3068. Epub 2018 Mar 6.

Department of Chemistry Ludwig-Maximilians-Universität München Butenandtstrasse 5-13 , 81377 München , Germany.

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http://dx.doi.org/10.1021/acs.joc.8b00192DOI Listing
March 2018

Selective Synthesis of Divergolide I.

J Am Chem Soc 2018 02 15;140(8):2748-2751. Epub 2018 Feb 15.

Department of Chemistry, Ludwig-Maximilians University Munich , Butenandtstraße 5-13, 81377 Munich, Germany.

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http://dx.doi.org/10.1021/jacs.7b13092DOI Listing
February 2018

A Predictive Approach for the Optical Control of Carbonic Anhydrase II Activity.

ACS Chem Biol 2018 03 9;13(3):793-800. Epub 2018 Feb 9.

Department of Chemistry , Ludwig-Maximilian-University Munich and Munich Center for Integrated Protein Science (CIPSM) , Butenandtstrasse 5-13 , 83177 Munich , Germany.

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http://dx.doi.org/10.1021/acschembio.7b00862DOI Listing
March 2018

Reversible optical control of F F -ATP synthase using photoswitchable inhibitors.

FEBS Lett 2018 02 1;592(3):343-355. Epub 2018 Feb 1.

Department of Chemistry, University of Munich, Germany.

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http://dx.doi.org/10.1002/1873-3468.12958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175411PMC
February 2018

The Chemist and the Architect.

Authors:
Dirk Trauner

Angew Chem Int Ed Engl 2018 04 27;57(16):4177-4191. Epub 2017 Dec 27.

Department of Chemistry, New York University, 100 Washington Square East, Room 712, New York, NY, 10003, USA.

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http://dx.doi.org/10.1002/anie.201708325DOI Listing
April 2018

PhoDAGs Enable Optical Control of Diacylglycerol-Sensitive Transient Receptor Potential Channels.

Cell Chem Biol 2018 02 21;25(2):215-223.e3. Epub 2017 Dec 21.

Center for Integrative Physiology and Molecular Medicine, Saarland University, 66421 Homburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2017.11.008DOI Listing
February 2018

Optical Control of a Biological Reaction-Diffusion System.

Angew Chem Int Ed Engl 2018 02 26;57(9):2362-2366. Epub 2018 Jan 26.

Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152, Martinsried, Germany.

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http://dx.doi.org/10.1002/anie.201712002DOI Listing
February 2018

Optical Control of Dopamine Receptors Using a Photoswitchable Tethered Inverse Agonist.

J Am Chem Soc 2017 12 13;139(51):18522-18535. Epub 2017 Dec 13.

Department of Chemistry and Center for Integrated Protein Science, Ludwig-Maximilians-Universität , Butenandtstraße 5-13, Munich 81377, Germany.

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http://dx.doi.org/10.1021/jacs.7b07659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942546PMC
December 2017

Synthesis of Photoswitchable Δ-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling.

J Am Chem Soc 2017 12 12;139(50):18206-18212. Epub 2017 Dec 12.

Department of Chemistry and Center for Integrated Protein Science, Ludwig Maximilians University Munich , Butenandtstraße 5-13, 81377 Munich, Germany.

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http://dx.doi.org/10.1021/jacs.7b06456DOI Listing
December 2017

Specificity and Speed: Tethered Photopharmacology.

Biochemistry 2017 10 14;56(39):5214-5220. Epub 2017 Sep 14.

Department of Chemistry and Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München , Butenandtstrasse 5-13, 81377 Munich, Germany.

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http://dx.doi.org/10.1021/acs.biochem.7b00687DOI Listing
October 2017

Total Synthesis of Crocagin A.

Angew Chem Int Ed Engl 2017 10 18;56(42):12848-12851. Epub 2017 Sep 18.

Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377, Munich, Germany.

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http://dx.doi.org/10.1002/anie.201612641DOI Listing
October 2017

Thiocarbonyl Ylide Chemistry Enables a Concise Synthesis of (±)-Hippolachnin A.

J Am Chem Soc 2017 08 16;139(34):11706-11709. Epub 2017 Aug 16.

Department of Chemistry, Ludwig-Maximilians-Universität München , Butenandtstraße 5-13, 81377 Munich, Germany.

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http://dx.doi.org/10.1021/jacs.7b06815DOI Listing
August 2017

Biomimetic Synthesis of Complex Flavonoids Isolated from Daemonorops "Dragon's Blood".

Angew Chem Int Ed Engl 2017 09 16;56(40):12332-12335. Epub 2017 Aug 16.

Department of Chemistry, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.

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http://dx.doi.org/10.1002/anie.201705390DOI Listing
September 2017

Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2.

Angew Chem Int Ed Engl 2017 10 30;56(41):12755-12759. Epub 2017 Aug 30.

Department of Chemistry, University of Munich, Butenandtstrasse 5-13, Haus F, 81377, Munich, Germany.

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http://dx.doi.org/10.1002/anie.201705387DOI Listing
October 2017

Total Synthesis of Lycopladine A and Carinatine A via a Base-Mediated Carbocyclization.

J Org Chem 2017 08 19;82(15):8206-8212. Epub 2017 Jul 19.

Department of Chemistry, Ludwig-Maximilians-Universität München , Butenandtstrasse 5-13, 81377 München, Germany.

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http://dx.doi.org/10.1021/acs.joc.7b00908DOI Listing
August 2017

Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone.

Chem Sci 2017 Jun 19;8(6):4644-4653. Epub 2017 Apr 19.

Department of Chemistry and Center for Integrated Protein Science , LMU Munich , Butenandtstr. 5-13 , 81377 Munich , Germany . Email: ; Email:

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http://dx.doi.org/10.1039/c6sc05044aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471452PMC
June 2017

Asymmetric Synthesis of the Antiviral Diterpene Wickerol A.

J Am Chem Soc 2017 07 7;139(28):9491-9494. Epub 2017 Jul 7.

Department of Chemistry and Center for Integrated Protein Science, Ludwig-Maximilian University Munich , Butenandtstraße 5-13, 81377 Munich, Germany.

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http://dx.doi.org/10.1021/jacs.7b05046DOI Listing
July 2017

Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held.

J Neurosci 2017 06 2;37(25):6043-6052. Epub 2017 Jun 2.

Cellular and Molecular Synaptic Function Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan,

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http://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.0179-1
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http://dx.doi.org/10.1523/JNEUROSCI.0179-17.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596501PMC
June 2017

Structure and Biosynthesis of Crocagins: Polycyclic Posttranslationally Modified Ribosomal Peptides from Chondromyces crocatus.

Angew Chem Int Ed Engl 2017 06 23;56(26):7407-7410. Epub 2017 May 23.

Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Center for Infection Research and Pharmaceutical Biotechnology, Saarland University, Campus, Building E8.1, 66123, Saarbrücken, Germany.

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http://dx.doi.org/10.1002/anie.201612640DOI Listing
June 2017

Optical control of AMPA receptors using a photoswitchable quinoxaline-2,3-dione antagonist.

Chem Sci 2017 Jan 24;8(1):611-615. Epub 2016 Aug 24.

Department of Chemistry and Center for Integrated Protein Science , Ludwig Maximilians University Munich , Butenandtstraße 5-13 , 81377 Munich , Germany . Email:

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http://dx.doi.org/10.1039/c6sc01621aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358534PMC
January 2017

Photoswitchable Inhibitor of a Glutamate Transporter.

ACS Chem Neurosci 2017 08 16;8(8):1668-1672. Epub 2017 May 16.

Department of Chemistry and Center for Integrated Protein Science (CIPSM), LMU Munich , 81377 Munich, Germany.

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http://dx.doi.org/10.1021/acschemneuro.7b00072DOI Listing
August 2017

Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors.

Proc Natl Acad Sci U S A 2017 04 10;114(17):E3546-E3554. Epub 2017 Apr 10.

Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720;

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http://dx.doi.org/10.1073/pnas.1619652114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410775PMC
April 2017

Light-Controlled Membrane Mechanics and Shape Transitions of Photoswitchable Lipid Vesicles.

Langmuir 2017 04 12;33(16):4083-4089. Epub 2017 Apr 12.

Photonics and Optoelectronics Group, Department of Physics and CeNS, Ludwig Maximilians University Munich , Amalienstraße 54, 80799 Munich, Germany.

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http://dx.doi.org/10.1021/acs.langmuir.7b01020DOI Listing
April 2017

Remote control of glucose homeostasis in vivo using photopharmacology.

Sci Rep 2017 03 22;7(1):291. Epub 2017 Mar 22.

Institute of Metabolism and Systems Research (IMSR) and Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham, Edgbaston, B15 2TT, UK.

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http://dx.doi.org/10.1038/s41598-017-00397-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428208PMC
March 2017

Selective Lithiation, Magnesiation, and Zincation of Unsymmetrical Azobenzenes Using Continuous Flow.

Org Lett 2017 04 15;19(7):1666-1669. Epub 2017 Mar 15.

Department Chemie, Ludwig-Maximilians-Universität , Butenandtstrasse 5-13, 81377 München, Germany.

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http://dx.doi.org/10.1021/acs.orglett.7b00460DOI Listing
April 2017

Furans as Versatile Synthons: Total Syntheses of Caribenol A and Caribenol B.

J Am Chem Soc 2017 03 10;139(11):4117-4122. Epub 2017 Mar 10.

Department of Chemistry and Center for Integrated Protein Science, Ludwig-Maximilians-Universität München , Butenandtstrasse 5-13, 81377 München, Germany.

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http://dx.doi.org/10.1021/jacs.7b00234DOI Listing
March 2017

Unravelling Photochemical Relationships Among Natural Products from .

ACS Cent Sci 2017 Jan 19;3(1):39-46. Epub 2016 Dec 19.

Department of Chemistry, Ludwig-Maximilians-Universität , 81377 Munich, Germany.

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http://dx.doi.org/10.1021/acscentsci.6b00293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269658PMC
January 2017

Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO).

Chem Sci 2016 23;7(3):2347-2352. Epub 2015 Nov 23.

Department of Chemistry and Center for Integrated Protein Science, Ludwig Maximilians University Munich, Butenandtstraße 5-13, 81377 Munich, Germany.

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http://dx.doi.org/10.1039/C5SC04084ADOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234268PMC
November 2015

A Conia-Ene-Type Cyclization under Basic Conditions Enables an Efficient Synthesis of (-)-Lycoposerramine R.

Angew Chem Int Ed Engl 2017 01 21;56(3):893-896. Epub 2016 Dec 21.

Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, 81377, München, Germany.

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http://dx.doi.org/10.1002/anie.201610021DOI Listing
January 2017

Enantioselective Synthesis and Racemization of (-)-Sinoracutine.

Angew Chem Int Ed Engl 2017 01 19;56(3):897-901. Epub 2016 Dec 19.

Department of Chemistry, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.

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http://doi.wiley.com/10.1002/anie.201608206
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http://dx.doi.org/10.1002/anie.201608206DOI Listing
January 2017

Optical control of GIRK channels using visible light.

Org Biomol Chem 2016 Dec;15(1):76-81

Department of Chemistry and Center for Integrated Protein Science, Ludwig Maximilians University Munich, Butenandtstraße 5-13, 81377 Munich, Germany.

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http://dx.doi.org/10.1039/c6ob02153kDOI Listing
December 2016

Optical Control of Lipid Rafts with Photoswitchable Ceramides.

J Am Chem Soc 2016 10 26;138(39):12981-12986. Epub 2016 Sep 26.

Department of Chemistry and Center for Integrated Protein Science, Ludwig Maximilians University Munich , Butenandtstraße 5-13, 81377 Munich, Germany.

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http://pubs.acs.org/doi/10.1021/jacs.6b07278
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http://dx.doi.org/10.1021/jacs.6b07278DOI Listing
October 2016

Photoswitchable diacylglycerols enable optical control of protein kinase C.

Nat Chem Biol 2016 09 25;12(9):755-62. Epub 2016 Jul 25.

Department of Chemistry and Center for Integrated Protein Science, Ludwig Maximilians University Munich, Munich, Germany.

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http://dx.doi.org/10.1038/nchembio.2141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101201PMC
September 2016

Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose.

Cell Metab 2016 09 21;24(3):389-401. Epub 2016 Jul 21.

Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London W12 0NN, UK; Institute of Metabolism and Systems Research (IMSR) and Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham, Birmingham B15 2TT, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B15 2TH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031557PMC
September 2016

A Synthesis of (±)-Aplydactone.

Angew Chem Int Ed Engl 2016 09 30;55(37):11251-5. Epub 2016 Jun 30.

Department of Chemistry, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.

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http://dx.doi.org/10.1002/anie.201604102DOI Listing
September 2016

Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand.

ACS Cent Sci 2015 Oct 16;1(7):383-93. Epub 2015 Oct 16.

Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, 81377 München, Germany; Munich Center for Integrated Protein Science, Butenandtstrasse 5-13, 81377 München, Germany.

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http://dx.doi.org/10.1021/acscentsci.5b00260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827557PMC
October 2015

Allosteric Optical Control of a Class B G-Protein-Coupled Receptor.

Angew Chem Int Ed Engl 2016 05 5;55(19):5865-8. Epub 2016 Apr 5.

Imperial College London, Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031193PMC
http://dx.doi.org/10.1002/anie.201600957DOI Listing
May 2016

6-[6-(Pyridin-2-yl)-1,2,4,5-tetra-zin-3-yl]pyridin-3-amine monohydrate.

Acta Crystallogr E Crystallogr Commun 2016 Feb 27;72(Pt 2):238-40. Epub 2016 Jan 27.

Ludwig-Maximilians-Universität, Department, Butenandtstrasse 5-13, 81377 München, Germany.

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http://dx.doi.org/10.1107/S2056989016000608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770950PMC
February 2016

A family of photoswitchable NMDA receptors.

Elife 2016 Mar 1;5. Epub 2016 Mar 1.

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.

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http://dx.doi.org/10.7554/eLife.12040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786437PMC
March 2016

Synthesis of Redshifted Azobenzene Photoswitches by Late-Stage Functionalization.

Chemistry 2016 Mar 17;22(13):4364-8. Epub 2016 Feb 17.

Department of Chemistry, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.

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http://dx.doi.org/10.1002/chem.201505061DOI Listing
March 2016

Expedient Synthesis of (+)-Lycopalhine A.

Angew Chem Int Ed Engl 2016 Feb 8;55(6):2191-4. Epub 2016 Jan 8.

Department of Chemistry, Ludwig-Maximilians-Universität München, 81377, Munich, Germany.

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http://dx.doi.org/10.1002/anie.201509602DOI Listing
February 2016

Synthetic approaches towards alkaloids bearing α-tertiary amines.

Nat Prod Rep 2016 Mar 1;33(3):491-522. Epub 2015 Dec 1.

Fakultät für Chemie und Pharmazie, Ludwig-Maximilians-Universität München, and Munich Center for Integrated Protein Science, Butenandtstr. 5 - 13, 81377 München, Germany.

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http://dx.doi.org/10.1039/c5np00096cDOI Listing
March 2016

Optical Control of Insulin Secretion Using an Incretin Switch.

Angew Chem Int Ed Engl 2015 Dec 2;54(51):15565-9. Epub 2015 Nov 2.

LMU Munich, Department of Chemistry and Centre for Integrated Protein Science (CIPSM), Butenandtstrasse 5-13, 81377 Munich (Germany).

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http://dx.doi.org/10.1002/anie.201506384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736448PMC
December 2015

Calculated Nuclear Magnetic Resonance Spectra of Polytwistane and Related Hydrocarbon Nanorods.

J Chem Theory Comput 2015 Mar;11(3):1020-6

Department of Chemistry, University of Munich (LMU), and Munich Center for Integrated Protein Science (CIPSM) , Butenandtstrasse 5-13, D-81377 Munich, Germany.

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http://dx.doi.org/10.1021/ct5011505DOI Listing
March 2015

The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signalling and gene expression of Legionella pneumophila.

Mol Microbiol 2016 Feb 27;99(4):778-93. Epub 2015 Nov 27.

Max von Pettenkofer Institute, Ludwig-Maximilians University, Pettenkoferstraße 9a, 80336, Munich, Germany.

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http://dx.doi.org/10.1111/mmi.13265DOI Listing
February 2016