Dirk Strumberg

Dirk Strumberg

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Dirk Strumberg

Dirk Strumberg

Publications by authors named "Dirk Strumberg"

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Pressurized intraperitoneal aerosol chemotherapy with low-dose cisplatin and doxorubicin (PIPAC C/D) in patients with gastric cancer and peritoneal metastasis: a phase II study.

Ther Adv Med Oncol 2019 13;11:1758835919846402. Epub 2019 May 13.

Department of General and Transplant Surgery, University Hospital Tübingen, Germany National Center for Pleura and Peritoneum, University Hospital, Tübingen, Germany.

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http://dx.doi.org/10.1177/1758835919846402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535725PMC
May 2019

A Distinct Oncogenerative Multinucleated Cancer Cell Serves as a Source of Stemness and Tumor Heterogeneity.

Cancer Res 2018 05 12;78(9):2318-2331. Epub 2018 Feb 12.

Institute of Molecular Oncology and Experimental Therapeutics. Division of Haematology and Oncology, Marienhospital Herne, Ruhr University Bochum, Medical School, Herne, Germany.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-17-1861DOI Listing
May 2018

Cytotoxic stress induces transfer of mitochondria-associated human endogenous retroviral RNA and proteins between cancer cells.

Oncotarget 2017 Nov 7;8(56):95945-95964. Epub 2017 Oct 7.

Institute for Molecular Oncology and Experimental Therapeutics, Department of Hematology and Medical Oncology, Marienhospital Herne, Ruhr-University of Bochum, Bochum, Germany.

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http://www.oncotarget.com/fulltext/21606
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http://dx.doi.org/10.18632/oncotarget.21606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707072PMC
November 2017

Preclinical evaluation of a diabody-based (177)Lu-radioimmunoconjugate for CD22-directed radioimmunotherapy in a non-Hodgkin lymphoma mouse model.

Cancer Lett 2016 10 11;381(2):296-304. Epub 2016 Aug 11.

Department of Medical Oncology, National Center for Tumor Diseases, Heidelberg University Hospital, Im Neuenheimer Feld 460, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.08.007DOI Listing
October 2016

Therapeutic potential of antiviral drugs targeting chemorefractory colorectal adenocarcinoma cells overexpressing endogenous retroviral elements.

J Exp Clin Cancer Res 2015 Aug 12;34:81. Epub 2015 Aug 12.

Institute for Molecular Oncology and Experimental Therapeutics, Division of Oncology and Hematology, Marienhospital Herne, Ruhr University of Bochum, Medical School, Marienhospital Herne, Duengelstr. 33, 44623, Herne, Germany.

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http://dx.doi.org/10.1186/s13046-015-0199-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542094PMC
August 2015

First-in-human phase I study of the liposomal RNA interference therapeutic Atu027 in patients with advanced solid tumors.

J Clin Oncol 2014 Dec 17;32(36):4141-8. Epub 2014 Nov 17.

Beate Schultheis and Dirk Strumberg, Marienhospital Herne/University of Bochum, Herne; Ansgar Santel, Christiane Vank, Frank Gebhardt, Oliver Keil, Christian Lange, Klaus Giese, Jörg Kaufmann, and Michael Khan, Silence Therapeutics, Berlin; and Joachim Drevs, UniFontis Clinic, Tübingen, Germany.

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http://dx.doi.org/10.1200/JCO.2013.55.0376DOI Listing
December 2014

Sarcomatoid non-small cell lung cancer responding to sunitinib.

Int J Clin Pharmacol Ther 2013 Jan;51(1):87-8

Department of Hematology and Oncology, Marienhospital Herne, Ruhr University Bochum, Germany. beate.schultheis@marienhospital-herne-de

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http://dx.doi.org/10.5414/cpp51087DOI Listing
January 2013

Phase I open-label study of cediranib, an oral inhibitor of VEGF signalling, in combination with the oral Src inhibitor saracatinib in patients with advanced solid tumours.

Invest New Drugs 2012 Oct 12;30(5):1962-71. Epub 2011 Oct 12.

Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisbug-Essen Essen, Hufelandstr. 55, 45122, Essen, Germany.

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http://dx.doi.org/10.1007/s10637-011-9754-xDOI Listing
October 2012

Phase II study of nimotuzumab, a humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody, in patients with locally advanced or metastatic pancreatic cancer.

Invest New Drugs 2012 Jun 21;30(3):1138-43. Epub 2010 Dec 21.

Department of Hematology and Medical Oncology, University of Bochum, Marienhospital Herne, Hölkeskampring 40, 44625, Herne, Germany.

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http://dx.doi.org/10.1007/s10637-010-9619-8DOI Listing
June 2012

Results of a phase II trial of S-1 as first-line treatment of metastatic pancreatic cancer (CESAR-study group).

Invest New Drugs 2012 Jun 12;30(3):1184-92. Epub 2011 Apr 12.

Department of Haematology and Medical Oncology, University of Bochum (Marienhospital Herne), Herne, Germany.

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http://link.springer.com/10.1007/s10637-011-9665-x
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http://dx.doi.org/10.1007/s10637-011-9665-xDOI Listing
June 2012

Regorafenib for cancer.

Expert Opin Investig Drugs 2012 Jun;21(6):879-89

University of Bochum, Marienhospital Herne, Department of Hematology and Medical Oncology, 40, 44625 Herne, Germany.

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http://dx.doi.org/10.1517/13543784.2012.684752DOI Listing
June 2012

Effect of food and a proton pump inhibitor on the pharmacokinetics of S-1 following oral administration of S-1 in patients with advanced solid tumors.

Cancer Chemother Pharmacol 2012 Mar 22;69(3):753-61. Epub 2011 Oct 22.

West German Cancer Center, University of Essen, Essen, Germany.

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http://dx.doi.org/10.1007/s00280-011-1761-2DOI Listing
March 2012

Sorafenib for the treatment of renal cancer.

Authors:
Dirk Strumberg

Expert Opin Pharmacother 2012 Feb 20;13(3):407-19. Epub 2012 Jan 20.

University of Bochum - Hematology and Oncology, Marienhospital Herne , Hölkeskampring 40, 44625 Herne , Germany.

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http://dx.doi.org/10.1517/14656566.2012.654776DOI Listing
February 2012

Paclitaxel in combination with sorafenib and bevacizumab in patients with locally advanced or metastatic solid tumors.

Int J Clin Pharmacol Ther 2012 Jan;50(1):72-3

Department of Hematology and Oncology, Marienhospital Herne, University of Bochum, Herne, Germany.

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http://dx.doi.org/10.5414/cpp50072DOI Listing
January 2012

Angioimmunoblastic T-cell lymphoma, combined with antiphospholipid syndrome and autoimmune thrombocytopenia (case report).

Int J Clin Pharmacol Ther 2012 Jan;50(1):74-5

Department of Hematology and Oncology, Marienhospital Herne, University of Bochum, Herne, Germany.

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http://dx.doi.org/10.5414/cpp50074DOI Listing
January 2012

Phase I clinical development of Atu027, a siRNA formulation targeting PKN3 in patients with advanced solid tumors.

Int J Clin Pharmacol Ther 2012 Jan;50(1):76-8

Department of Hematology and Oncology, Marienhospital Herne, University of Bochum, Herne, Germany.

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http://dx.doi.org/10.5414/cpp50076DOI Listing
January 2012

Observation of de novo bladder dysfunction under treatment with Her2-neu antibodies.

Urol Int 2011 27;86(1):80-4. Epub 2010 Nov 27.

Department of Urology, Ruhr-Universität Bochum, Bochum, Germany.

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http://dx.doi.org/10.1159/000317441DOI Listing
July 2011

Combined detection of Her2/neu gene amplification and protein overexpression in effusions from patients with breast and ovarian cancer.

J Cancer Res Clin Oncol 2010 Sep 9;136(9):1389-400. Epub 2010 Mar 9.

Marienhospital Herne, Medizinische Klinik III: Hämatologie und Onkologie, Klinikum der Ruhr-Universität Bochum, Hölkeskampring 40, 44625, Herne, Germany.

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http://dx.doi.org/10.1007/s00432-010-0790-2DOI Listing
September 2010

Patient-based strategy for systemic treatment of metastatic renal cell carcinoma.

Expert Rev Anticancer Ther 2010 Apr;10(4):585-96

Klinikum Region Hannover GmbH, Krankenhaus Siloah, Medizinische Klinik III, Roesebeckstr 15, 30449 Hannover, Germany.

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http://dx.doi.org/10.1586/era.10.25DOI Listing
April 2010

Multicenter phase II trial of S-1 plus cisplatin in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma.

J Clin Oncol 2006 Feb;24(4):663-7

Department of Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1200/JCO.2005.04.2994DOI Listing
February 2006

Preclinical and clinical development of the oral multikinase inhibitor sorafenib in cancer treatment.

Authors:
Dirk Strumberg

Drugs Today (Barc) 2005 Dec;41(12):773-84

Department of Hematology and Medical Oncology, Marienhospital Herne, University of Bochum, Herne, Germany.

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http://dx.doi.org/10.1358/dot.2005.41.12.937959DOI Listing
December 2005

Phase II trial of cisplatin, gemcitabine and treosulfan in patients with metastatic uveal melanoma.

Melanoma Res 2005 Jun;15(3):205-7

Department of Internal Medicine III (Haematology, Oncology and Transfusion Medicine), Charité, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany.

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June 2005

The Raf kinase inhibitor BAY 43-9006 reduces cellular uptake of platinum compounds and cytotoxicity in human colorectal carcinoma cell lines.

Anticancer Drugs 2005 Feb;16(2):129-36

Department of Internal Medicine and Medical Oncology, West German Cancer Centre, University Medical School of Essen, Essen, Germany.

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http://dx.doi.org/10.1097/00001813-200502000-00003DOI Listing
February 2005

Raf kinase inhibitors in oncology.

Onkologie 2005 Feb;28(2):101-7

Department of Internal Medicine and Medical Oncology, West German Cancer Center, University of Essen, Germany.

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http://dx.doi.org/10.1159/000083373DOI Listing
February 2005

Metal-dependent inhibition of HIV-1 integrase.

J Med Chem 2002 Dec;45(26):5661-70

Department of Pharmaceutical Sciences, University of Southern California, School of Pharmacy, 1985 Zonal Avenue, Los Angeles, California 90089, USA.

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http://dx.doi.org/10.1021/jm0201417DOI Listing
December 2002

Importance of the fourth alpha-helix within the CAP homology domain of type II topoisomerase for DNA cleavage site recognition and quinolone action.

Antimicrob Agents Chemother 2002 Sep;46(9):2735-46

Department of Internal Medicine and Medical Oncology, West German Cancer Center, University Medical School of Essen, 45122 Essen, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC127396PMC
http://dx.doi.org/10.1128/aac.46.9.2735-2746.2002DOI Listing
September 2002