Dirk Schadendorf

Dirk Schadendorf

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Dirk Schadendorf

Publications by authors named "Dirk Schadendorf"

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Prognostic factors for pulmonary metastasectomy in malignant melanoma: size matters.

Eur J Cardiothorac Surg 2019 Dec;56(6):1104-1109

Department of Thoracic Surgery, University Medicine Essen-Ruhrlandklinik, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1093/ejcts/ezz211DOI Listing
December 2019

Corrigendum to 'Prediction of melanoma evolution in melanocytic nevi via artificial intelligence: A call for prospective data' [Eur J Cancer, 119 (September 2019) Pages 30-34].

Eur J Cancer 2019 Nov 7. Epub 2019 Nov 7.

Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany; National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 460, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.10.003DOI Listing
November 2019

ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope.

Eur J Immunol 2019 Nov 15. Epub 2019 Nov 15.

Friedrich Loeffler Institut für Medizinische Mikrobiologie-Virologie, Universitätsmedizin Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1002/eji.201948116DOI Listing
November 2019

Complex Formation with Monomeric α-Tubulin and Importin 13 Fosters c-Jun Protein Stability and Is Required for c-Jun's Nuclear Translocation and Activity.

Cancers (Basel) 2019 Nov 17;11(11). Epub 2019 Nov 17.

Institute of Biochemistry (Emil-Fischer Center), Friedrich-Alexander University, Erlangen-Nürnberg, 91054 Erlangen, Germany.

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http://dx.doi.org/10.3390/cancers11111806DOI Listing
November 2019

An Animal Model of Cutaneous Cyst Development Enables the Identification of Three Quantitative Trait Loci, Including the Homologue of a Human Locus (TRICY1).

J Invest Dermatol 2019 Oct 27;139(10):2235-2238.e5. Epub 2019 Apr 27.

Institute of Pathology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1016/j.jid.2019.03.1154DOI Listing
October 2019

Superior skin cancer classification by the combination of human and artificial intelligence.

Eur J Cancer 2019 Oct 10;120:114-121. Epub 2019 Sep 10.

National Center for Tumor Diseases, German Cancer Research Center, Heidelberg, Germany; Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.07.019DOI Listing
October 2019

Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.

N Engl J Med 2019 10 28;381(16):1535-1546. Epub 2019 Sep 28.

From the Royal Marsden NHS Foundation Trust, London (J.L.), and the College of Medicine, Swansea University, Swansea (J.W.) - both in the United Kingdom; the Oncology Institute of Veneto IRCCS, Padua (V.C.-S.), the European Institute of Oncology, IRCCS, Milan (P.F.F.), Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples (P.A.A.), the Immunotherapy and Somatic Cell Therapy Unit, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola (M.G.), and the Center for Immuno-Oncology, Medical Oncology and Immunotherapy, University Hospital, Siena (M.M.) - all in Italy; the University of Colorado Cancer Center, Aurora (R.G.); Aix-Marseille University, Assistance Publique-Hôpitaux de Marseille Hôpital Timone, Marseille (J.-J.G.), and Université de Paris, INSERM Unité 976, Assistance Publique-Hôpitaux de Paris Dermatology and Centres d'Investigation Clinique, Saint Louis Hospital, Paris (C.L.) - both in France; the Maria Sklodowska-Curie Institute-Oncology Center, Warsaw, Poland (P.R.); the University of Michigan, Ann Arbor (C.D.L.); Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas (C.L.C.); the Department of Dermatology, University of Essen, Essen, and the German Cancer Consortium, Heidelberg - both in Germany (D.S.); Universitäts Spital, Zurich, Switzerland (R.D.); Cross Cancer Institute, Edmonton, AB (M.S.), and the Princess Margaret Cancer Centre, Toronto (D.H.) - both in Canada; Tasman Oncology Research, Southport, QLD (A.H.), the Crown Princess Mary Cancer Centre, Melanoma Institute Australia, University of Sydney, Sydney, NSW (M.S.C., G.V.L.), and the Royal North Shore and Mater Hospitals (G.V.L.), Sydney, and the Peter MacCallum Cancer Centre, Melbourne, VIC (G.M.) - all in Australia; General University Hospital Gregorio Marañon and Centro de Investigación Biomédica en Red de Oncología, Madrid (I.M.-R.); the Netherlands Cancer Institute, Amsterdam (J.H.); the Leuven Cancer Institute, Department of General Medical Oncology, University Hospital Leuven, Leuven, Belgium (P.S.); University of California San Diego Health-La Jolla Moores Cancer Center, La Jolla (G.A.D.); the Department of Oncology, Odense University Hospital, Odense, Denmark (L.B.); Bristol-Myers Squibb, Princeton, NJ (J.I.R., A.B., A.M.); Dana-Farber Cancer Institute, Boston (F.S.H.); and the Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York (J.D.W.).

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http://dx.doi.org/10.1056/NEJMoa1910836DOI Listing
October 2019

Deep learning outperformed 11 pathologists in the classification of histopathological melanoma images.

Eur J Cancer 2019 Sep 18;118:91-96. Epub 2019 Jul 18.

National Center for Tumor Diseases, German Cancer Research Center, Heidelberg, Germany; Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.06.012DOI Listing
September 2019

Deep neural networks are superior to dermatologists in melanoma image classification.

Eur J Cancer 2019 Sep 8;119:11-17. Epub 2019 Aug 8.

Department of Dermatology, Heidelberg University, Mannheim, Germany; Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejca.2019.05.023DOI Listing
September 2019

Impact of American Joint Committee on Cancer 8th edition classification on staging and survival of patients with melanoma.

Eur J Cancer 2019 Sep 8;119:18-29. Epub 2019 Aug 8.

Department of Dermatology, University Hospital Essen, Essen, Germany and German Cancer Consortium of Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.06.011DOI Listing
September 2019

Prediction of melanoma evolution in melanocytic nevi via artificial intelligence: A call for prospective data.

Eur J Cancer 2019 Sep 8;119:30-34. Epub 2019 Aug 8.

Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany; National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 460, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.07.009DOI Listing
September 2019

Clinical and genetic analysis of melanomas arising in acral sites.

Eur J Cancer 2019 Sep 14;119:66-76. Epub 2019 Aug 14.

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany; Dermatological Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.07.008DOI Listing
September 2019

The Era of Checkpoint Inhibition: Lessons Learned from Melanoma.

Recent Results Cancer Res 2020 ;214:169-187

Department of Dermatology, University Hospital Essen, University Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany.

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http://dx.doi.org/10.1007/978-3-030-23765-3_6DOI Listing
September 2019

Quality, Readability, and Understandability of German Booklets Addressing Melanoma Patients.

J Cancer Educ 2019 Aug;34(4):760-767

Department of Dermatology, Dresden University Hospital Carl Gustav Carus, Fetscherstr. 74, 01307, Dresden, Germany.

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http://dx.doi.org/10.1007/s13187-018-1369-xDOI Listing
August 2019

Predictors of quality of life in melanoma patients 4 years after diagnosis: Results of a nationwide cohort study in Germany.

J Psychosoc Oncol 2018 Nov-Dec;36(6):734-753. Epub 2018 Oct 15.

b Department of Dermatology , University Hospital Essen, University of Duisburg-Essen , Essen , Germany.

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https://www.tandfonline.com/doi/full/10.1080/07347332.2018.1
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http://dx.doi.org/10.1080/07347332.2018.1499691DOI Listing
August 2019

Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma.

N Engl J Med 2019 08 4;381(7):626-636. Epub 2019 Jun 4.

From Institut Gustave Roussy and Paris-Sud-Paris-Saclay University, Villejuif (C.R.), Aix-Marseille University, Marseille (J.J.G.), and Assistance Publique-Hôpitaux de Paris Dermatology and Clinical Investigation Center, Unité 976, Université de Paris, Hôpital Saint-Louis, Paris (C.L.) - all in France; Moscow City Oncology Hospital, Moscow (D. Stroyakovskiy), and the Petrov Research Institute of Oncology, St. Petersburg (E.L.) - both in Russia; Przychodnia Lekarska Komed, Konin (B.K.), the University of Medical Sciences, Poznań (A.M.), and the Maria Skłodowska-Curie Institute-Oncology Center, Warsaw (P.R.) - all in Poland; the University Hospital Schleswig-Holstein, Kiel (A.H.), the Department of Dermatology, University of Tübingen, Tübingen (C.G.), University Hospital Essen, Essen (D. Schadendorf), and the German Cancer Consortium, Heidelberg (D. Schadendorf) - all in Germany; the Veneto Institute of Oncology, Padua (V.C.S.), and Papa Giovanni XXIII Hospital, Bergamo (M.M.) - both in Italy; the Ella Lemelbaum Institute for Immuno-Oncology and Melanoma, Sheba Medical Center, Tel Hashomer (J.S.), and Sackler Medical School, Tel Aviv University, Tel Aviv (J.S.) - both in Israel; Dnipropetrovsk State Medical Academy, Dnipropetrovsk, Ukraine (I.B.); Laiko General Hospital, National and Kapodistrian University of Athens School of Medicine, Athens (H.G.); the Netherlands Cancer Institute, Amsterdam (J.B.A.G.H.); Mount Vernon Cancer Centre, Northwood, United Kingdom (P.D.N.); the University of California, Los Angeles, Los Angeles (A.R.); the University of Texas M.D. Anderson Cancer Center, Houston (M.A.D.); Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston (K.T.F.); Novartis Pharma, Basel, Switzerland (P.B.); Novartis Pharmaceuticals, East Hanover, NJ (M.T., E.G., M.V.); and the Melanoma Institute Australia, the University of Sydney, and Royal North Shore and Mater Hospitals, Sydney (G.V.L.).

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http://dx.doi.org/10.1056/NEJMoa1904059DOI Listing
August 2019

Cardiovascular Adverse Events Associated With BRAF and MEK Inhibitors: A Systematic Review and Meta-analysis.

JAMA Netw Open 2019 Aug 2;2(8):e198890. Epub 2019 Aug 2.

West German Heart and Vascular Center, Department of Cardiology and Vascular Medicine, University Hospital Essen, Essen, Germany.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.8890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692687PMC
August 2019

Pathologist-level classification of histopathological melanoma images with deep neural networks.

Eur J Cancer 2019 Jul 23;115:79-83. Epub 2019 May 23.

National Center for Tumor Diseases, German Cancer Research Center, Heidelberg, Germany; Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.04.021DOI Listing
July 2019

Efficacy of PD-1-based immunotherapy after radiologic progression on targeted therapy in stage IV melanoma.

Eur J Cancer 2019 Jul 15;116:207-215. Epub 2019 Jun 15.

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.05.015DOI Listing
July 2019

Targeting the H3K4 Demethylase KDM5B Reprograms the Metabolome and Phenotype of Melanoma Cells.

J Invest Dermatol 2019 Jun 21. Epub 2019 Jun 21.

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium, University of Duisburg-Essen, Duisburg/Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.06.124DOI Listing
June 2019

Reply to E. Hindié and K.R. Hess.

J Clin Oncol 2019 May 2;37(15):1356-1358. Epub 2019 Apr 2.

Georgina V. Long, MD, PhD, Melanoma Institute Australia, The University of Sydney, and Royal North Shore and Mater Hospitals, Sydney, NSW, Australia; Reinhard Dummer, MD, University Hospital Zürich Skin Cancer Center, Zürich, Switzerland; Dirk Schadendorf, MD, PhD, University Hospital Essen, Essen, Germany, and German Cancer Consortium, Heidelberg, Germany; Mario Santinami, MD, Fondazione Istituto Nazionale Tumori, Milan, Italy; Victoria Atkinson, MD, Princess Alexandra Hospital, Gallipoli Medical Research Foundation, and University of Queensland, Brisbane, QLD, Australia; Mario Mandalà, MD, Papa Giovanni XXIII Cancer Center Hospital, Bergamo, Italy; Vanna Chiarion-Sileni, MD, Veneto Institute of Oncology-Istituto di Ricovero e Cura a Carattere Scientifico, Padua, Italy; James Larkin, MD, PhD, Royal Marsden National Health Service Foundation Trust, London, United Kingdom; Marta Nyakas, MD, Oslo University Hospital, Oslo, Norway; Caroline Dutriaux, MD, Centre Hospitalier Universitaire de Bordeaux, Hôpital Saint-André, Bordeaux, France; Andrew Haydon, MD, PhD, The Alfred Hospital, Melbourne, VIC, Australia; Caroline Robert, MD, PhD, Institute Gustave Roussy, Paris, France; Laurent Mortier, MD, PhD, Université de Lille, Institut National de la Santé et de la Recherche Médicale U 1189, Centre Hospitalier Universitaire Lille, Lille, France; Jacob Schachter, MD, PhD, Sheba Medical Center, Tel HaShomer, Israel, and Tel Aviv University, Tel Aviv, Israel; Thierry Lesimple, MD, MSc, Centre Eugène Marquis, Rennes, France; Ruth Plummer, MD, PhD, Freeman Hospital and Newcastle University, Newcastle upon Tyne, United Kingdom; Kohinoor Dasgupta, PhD, Novartis Healthcare, Hyderabad, India; Tomas Haas, PhD, Novartis AG, Basel, Switzerland; Mark Shilkrut, MD, PhD and Eduard Gasal, MD, Novartis Pharmaceuticals, East Hanover, NJ; Richard Kefford, MD, PhD, Melanoma Institute Australia, The University of Sydney, Macquarie University, and Westmead Hospital, Sydney, NSW, Australia; John M. Kirkwood, MD, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA; and Axel Hauschild, MD, University Hospital Schleswig-Holstein, Kiel, Germany.

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http://ascopubs.org/doi/10.1200/JCO.19.00004
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http://dx.doi.org/10.1200/JCO.19.00004DOI Listing
May 2019

Deep learning outperformed 136 of 157 dermatologists in a head-to-head dermoscopic melanoma image classification task.

Eur J Cancer 2019 May 10;113:47-54. Epub 2019 Apr 10.

National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 460, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejca.2019.04.001DOI Listing
May 2019

Unmet information needs of patients with melanoma in Germany.

Melanoma Res 2019 04;29(2):196-204

Department of Dermatology, Dresden University Hospital Carl Gustav Carus, Dresden.

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http://dx.doi.org/10.1097/CMR.0000000000000464DOI Listing
April 2019

The prognostic value of sentinel lymph nodes on distant metastasis-free survival in patients with high-risk squamous cell carcinoma.

Eur J Cancer 2019 Apr 5;111:107-115. Epub 2019 Mar 5.

Department of Dermatology, Venerology and Allergology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; West German Cancer Center, University Duisburg-Essen, 45122 Essen, Germany; German Cancer Consortium (DKTK), 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.02.004DOI Listing
April 2019

[Merkel cell carcinoma].

Hautarzt 2019 Mar;70(3):215-227

Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Essen, Hufelandstraße 55, 45147, Essen, Deutschland.

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http://dx.doi.org/10.1007/s00105-019-4360-5DOI Listing
March 2019

Immunotherapy in non-melanoma skin cancer: updates and new perspectives.

Drugs Context 2019 25;8:212583. Epub 2019 Mar 25.

Department for Dermatology, Venerology and Allergology, University Hospital Essen, Essen, Germany.

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http://dx.doi.org/10.7573/dic.212583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434981PMC
March 2019

Can integrated 18F-FDG PET/MR replace sentinel lymph node resection in malignant melanoma?

Eur J Nucl Med Mol Imaging 2018 11 6;45(12):2093-2102. Epub 2018 Jun 6.

Medical Faculty, Department of Nuclear Medicine, Univ Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1007/s00259-018-4061-9DOI Listing
November 2018

Patient-reported outcomes with nivolumab in advanced solid cancers.

Cancer Treat Rev 2018 Nov 2;70:75-87. Epub 2018 Aug 2.

Bristol-Myers Squibb, Rt 206 & Province Line Road, Princeton, NJ 08543, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2018.08.001DOI Listing
November 2018

Telomere length, telomerase reverse transcriptase promoter mutations, and melanoma risk.

Genes Chromosomes Cancer 2018 11 11;57(11):564-572. Epub 2018 Sep 11.

Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1002/gcc.22669DOI Listing
November 2018

Re: van Poppelen et al.: Genetic background of iris melanomas and iris melanocytic tumors of uncertain malignant potential (Ophthalmology. 2018;125:904-912).

Ophthalmology 2018 11;125(11):e78-e79

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany; Dermatopathologie bei Mainz, Nieder-Olm, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01616420183090
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http://dx.doi.org/10.1016/j.ophtha.2018.05.021DOI Listing
November 2018

Skin Cancer Classification Using Convolutional Neural Networks: Systematic Review.

J Med Internet Res 2018 10 17;20(10):e11936. Epub 2018 Oct 17.

National Center for Tumor Diseases, Department of Translational Oncology, German Cancer Research Center, Heidelberg, Germany.

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http://www.jmir.org/2018/10/e11936/
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http://dx.doi.org/10.2196/11936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231861PMC
October 2018

Longer Follow-Up Confirms Relapse-Free Survival Benefit With Adjuvant Dabrafenib Plus Trametinib in Patients With Resected BRAF V600-Mutant Stage III Melanoma.

J Clin Oncol 2018 Oct 22:JCO1801219. Epub 2018 Oct 22.

Axel Hauschild, University Hospital Schleswig-Holstein, Kiel; Dirk Schadendorf, University Hospital Essen, Essen; German Cancer Consortium, Heidelberg, Germany; Reinhard Dummer, University Hospital Zürich Skin Cancer Center, Zürich; Tomas Haas, Novartis AG, Basel, Switzerland; Mario Santinami, Fondazione Istituto Nazionale Tumori, Milan; Mario Mandalà, Papa Giovanni XXIII Cancer Center Hospital, Bergamo; Vanna Chiarion-Sileni, Veneto Institute of Oncology-Istituto di Ricovero e Cura a Carattere Scientifico, Padova, Italy; Victoria Atkinson, Princess Alexandra Hospital; Gallipoli Medical Research Foundation; University of Queensland, Brisbane, Queensland; Andrew Haydon, The Alfred Hospital, Melbourne, Victoria; Richard Kefford, Macquarie University; Westmead Hospital; Richard Kefford and Georgina V. Long, Melanoma Institute Australia; University of Sydney; Royal North Shore and Mater Hospitals, Sydney, New South Wales, Australia; James Larkin, Royal Marsden National Health Service Foundation Trust, London; Ruth Plummer, Freeman Hospital and Newcastle University, Newcastle upon Tyne, United Kingdom; Marta Nyakas, Oslo University Hospital, Oslo, Norway; Caroline Dutriaux, Centre Hospitalier Universitaire de Bordeaux, Hôpital Saint-André, Bordeaux; Caroline Robert, Institute Gustave Roussy, Paris; Laurent Mortier, Université de Lille, Institut National de la Santé et de la Recherche Médicale U1189, Centre Hospitalier Universitaire de sa Region Lille, Lille; Thierry Lesimple, Centre Eugène Marquis, Rennes, France; Jacob Schachter, Sheba Medical Center, Tel Hashomer; Tel Aviv University, Tel Aviv, Israel; Kohinoor Dasgupta, Novartis Healthcare, Hyderabad, India; Mark Shilkrut and Eduard Gasal, Novartis Pharmaceuticals Corporation, East Hanover, NJ; and John M. Kirkwood, UPMC Hillman Cancer Center; University of Pittsburgh, Pittsburgh, PA.

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http://ascopubs.org/doi/10.1200/JCO.18.01219
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http://dx.doi.org/10.1200/JCO.18.01219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286159PMC
October 2018

Role of Elevated Copy Number as a Prognostic and Progression Marker for Cutaneous Melanoma.

Clin Cancer Res 2018 09 18;24(17):4119-4125. Epub 2018 May 18.

Center for Melanoma Research and Treatment, California Pacific Medical Center (CPMC) Research Institute, San Francisco, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125189PMC
September 2018

Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling.

Clin Cancer Res 2018 09 11;24(18):4494-4504. Epub 2018 Jun 11.

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0763DOI Listing
September 2018

Facial-Aging App Availability in Waiting Rooms as a Potential Opportunity for Skin Cancer Prevention.

JAMA Dermatol 2018 09;154(9):1085-1086

Department of Dermatology, University Hospital of Essen, Essen, Germany.

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http://dx.doi.org/10.1001/jamadermatol.2018.1907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143041PMC
September 2018

Information-seeking and use of information resources among melanoma patients of German skin cancer centers.

J Dtsch Dermatol Ges 2018 Sep 9;16(9):1093-1101. Epub 2018 Aug 9.

Department of Dermatology, Dresden University Hospital Carl Gustav Carus, Dresden, Germany.

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http://dx.doi.org/10.1111/ddg.13630DOI Listing
September 2018

Informationssuche und Nutzung von Informationsquellen durch Melanompatienten deutscher Hautkrebszentren.

J Dtsch Dermatol Ges 2018 Sep;16(9):1093-1102

Klinik und Poliklinik für Dermatologie, Universitätsklinikum Carl Gustav Carus, Dresden, Deutschland.

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http://dx.doi.org/10.1111/ddg.13630_gDOI Listing
September 2018

Melanoma.

Lancet 2018 09;392(10151):971-984

Department of Dermatology, University Hospital Essen, Essen, Germany; German Cancer Consortium, Heidelberg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183155
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http://dx.doi.org/10.1016/S0140-6736(18)31559-9DOI Listing
September 2018

Patterns of disease control and survival in patients with melanoma brain metastases undergoing immune-checkpoint blockade.

Eur J Cancer 2018 08 12;99:58-65. Epub 2018 Jun 12.

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, 97080 Würzburg, Germany; Department of Dermatology, Venereology and Allergology, University Hospital Essen, University Duisburg-Essen, Essen, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2018.05.012DOI Listing
August 2018

MEK inhibition may increase survival of NRAS-mutated melanoma patients treated with checkpoint blockade: Results of a retrospective multicentre analysis of 364 patients.

Eur J Cancer 2018 07 26;98:10-16. Epub 2018 May 26.

Department of Dermatology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Ulmenweg 18, 91054 Erlangen, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049183081
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http://dx.doi.org/10.1016/j.ejca.2018.04.010DOI Listing
July 2018

PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma.

N Engl J Med 2018 07 4;379(4):341-351. Epub 2018 Jun 4.

From the Departments of Dermatology and Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston (M.R.M.), and South Texas Accelerated Research Therapeutics (START), San Antonio (K.P.P.) - both in Texas; the Department of Medical Oncology, Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, VIC (D.R., A.A.T.), the Department of Medical Oncology, Royal North Shore Hospital, St. Leonards, VIC (A.G.), the Department of Medical Oncology, Sir Charles Gairdner Hospital, Perth, WA (A.M.L.), and Royal Brisbane and Women's Hospital and University of Queensland, Brisbane (B.G.M.H.) - all in Australia; the Department of Dermatology, Brigham and Women's Hospital (C.D.S.), the Department of Dermatology, Harvard Medical School (C.D.S.), and the Department of Medical Oncology, Dana-Farber Cancer Institute (G.R.) - all in Boston; Schleswig-Holstein University Hospital, Kiel (A.H.), and University Hospital Essen, Essen and German Cancer Consortium, Essen (D.S.) - both in Germany; University of Colorado Denver, School of Medicine, Aurora (K.D.L.); the Departments of Head and Neck-Endocrine Oncology (C.H.C.) and Cutaneous Oncology (N.I.K.), H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; the Division of Medical Oncology, Department of Medicine, Washington University School of Medicine, St. Louis (L.H.-A.); the Department of Dermatology, Stanford University School of Medicine, Redwood City (A.L.S.C.), and the Division of Dermatology, City of Hope, Duarte (B.M.) - both in California; the Department of Medicine, Head and Neck Medical Oncology, Memorial Sloan Kettering Cancer Center, New York (L.A.D.), and Regeneron Pharmaceuticals, Tarrytown (F.S., M.M., K.M., G.D.Y., I.L., M.G.F.) - both in New York; Regeneron Pharmaceuticals, Basking Ridge, NJ (B.G., S.L., J.L., J.B., E.S.); University of Arizona Cancer Center, Tucson (H.M.B.), and Banner MD Anderson Cancer (J.H.) and the Department of Medical Oncology, Banner MD Anderson Cancer Center (J.N.), Gilbert - all in Arizona; Medical Oncology Department, Vall D'Hebron University Hospital (I.B.), and Institut Català D'Oncologia, Oncobell Program (IDIBELL), L'Hospitalet de Llobregat (M.G.-M.), Barcelona, and START Madrid-FJD, Hospital Fundación Jiménez Díaz, Madrid (V.M.) - all in Spain; Sarah Cannon Research Institute, Nashville (M.L.J.); and the Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta (T.K.O.).

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http://www.nejm.org/doi/10.1056/NEJMoa1805131
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July 2018

STAT5 expression correlates with recurrence and survival in melanoma patients treated with interferon-α.

Melanoma Res 2018 06;28(3):204-210

Department of Dermatology and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg.

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http://Insights.ovid.com/crossref?an=00008390-900000000-9931
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http://dx.doi.org/10.1097/CMR.0000000000000435DOI Listing
June 2018

Tumor CDKN2A-Associated JAK2 Loss and Susceptibility to Immunotherapy Resistance.

J Natl Cancer Inst 2018 06;110(6):677-681

Department of Dermatology, University Hospital Essen, University Duisburg-Essen, and German Cancer Consortium partner site Essen/Düsseldorf, Essen, Germany (DKTK).

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http://dx.doi.org/10.1093/jnci/djx271DOI Listing
June 2018

Dose-dependent toxicity of ipilimumab in metastatic melanoma.

Eur J Cancer 2018 05 21;95:104-108. Epub 2018 Feb 21.

Department of Dermatology, University of Duisburg-Essen, Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2018.01.088DOI Listing
May 2018

Liquid Profiling of Circulating Tumor DNA in Plasma of Melanoma Patients for Companion Diagnostics and Monitoring of BRAF Inhibitor Therapy.

Clin Chem 2018 05 26;64(5):830-842. Epub 2018 Feb 26.

Department of Clinical Chemistry, University Medical Centre, Ruprecht-Karls University of Heidelberg, Mannheim, Germany;

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http://dx.doi.org/10.1373/clinchem.2017.281543DOI Listing
May 2018

Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma.

N Engl J Med 2018 May 15;378(19):1789-1801. Epub 2018 Apr 15.

From the Gustave Roussy Cancer Campus Grand Paris and University Paris-Saclay, Villejuif (A.M.M.E., C.R.), Hospices Civils de Lyon Cancer Institute, Cancer Research Center of Lyon, Lyon University, Lyon (S.D.), and Aix-Marseille University, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, Marseille (J.-J.G.) - all in France; Netherlands Cancer Institute-Antoni van Leeuwenhoek (C.U.B., A.C.J.A.) and VU University Medical Center (A.J.M.E.), Amsterdam, and Radboud University Medical Center Nijmegen, Nijmegen (R.K.) - all in the Netherlands; Azienda Ospedaliera Papa Giovanni XXIII, Bergamo (M. Mandala), Istituto Nazionale Tumori Istituto di Ricovero e Cura a Carattere Scientifico Fondazione G. Pascale, Naples (P.A.A.), and Universita Degli Studi Di Siena-Policlinico le Scotte, Siena (M. Maio) - all in Italy; Melanoma Institute Australia, the University of Sydney, and Mater and Royal North Shore Hospitals (G.V.L.) and Westmead and Blacktown Hospitals, Melanoma Institute Australia and the University of Sydney (M.S.C.), Sydney, Princess Alexandra Hospital, University of Queensland, Brisbane (V.A.), Alfred Hospital (A.H.) and Peter MacCallum Cancer Centre (S. Sandhu), Melbourne, VIC, and Fiona Stanley Hospital-University of Western Australia-Edith Cowan University Perth, Perth (A.K.) - all in Australia; Cancer Research Center, Moscow (M.L.); Royal Marsden Hospital, London (J.L.); Hospital Clinic Universitari de Barcelona, Barcelona (S.P.); Maria Sklodowska-Curie Institute-Oncology Center, Warsaw, Poland (P.R.); University Hospital Essen, Essen and German Cancer Consortium, Heidelberg (D.S.), and the Skin Cancer Center, Department of Dermatology, Hannover Medical School, Hannover (R.G.) - all in Germany; Washington University School of Medicine, St. Louis (L.H.-A.); Centre Hospitalier de l'Université de Montréal (CHUM), Centre de Recherche du CHUM, Montreal (R.J.); Christie NHS Foundation Trust, Manchester, United Kingdom (P.L.); Merck, Kenilworth, NJ (N.I.); and the European Organization for the Research and Treatment of Cancer Headquarters, Brussels (S.M., S. Suciu).

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http://dx.doi.org/10.1056/NEJMoa1802357DOI Listing
May 2018

Postsurgical Treatment of Split Skin Graft Donor Sites in Dermatological Departments.

Int J Low Extrem Wounds 2018 Mar 5;17(1):22-29. Epub 2018 Mar 5.

1 Department of Dermatology, Venerology and Allergology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1177/1534734617747685DOI Listing
March 2018