Publications by authors named "Dirk J de Jong"

81Publications

Prevalence of- and risk factors for work disability in Dutch patients with inflammatory bowel disease.

World J Gastroenterol 2017 Dec;23(46):8182-8192

Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, 9700 RB Groningen, the Netherlands.

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December 2017

The NOD2 receptor is crucial for immune responses towards New World Leishmania species.

Sci Rep 2017 11 9;7(1):15219. Epub 2017 Nov 9.

Department of Internal Medicine and Radboud Center of Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.

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November 2017

Clinical Predictors of Future Nonadherence in Inflammatory Bowel Disease.

Inflamm Bowel Dis 2017 09;23(9):1568-1576

1Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, the Netherlands; 2Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands; 3Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands; 4Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, the Netherlands; 5Department of Gastroenterology and Hepatology (Co-MIK), Zuyderland Medical Center, Heerlen, Sittard, Geleen, the Netherlands; 6Department of Gastroenterology and Hepatology, Diaconessenhuis, Leiden, the Netherlands; 7Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, the Netherlands; 8Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands; 9Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands; 10Department of Gastroenterology and Hepatology, Antonius Hospital, Nieuwegein, the Netherlands; 11Department of Gastroenterology and Hepatology, Slingeland Hospital, Doetinchem, the Netherlands; 12Department of Gastroenterology and Hepatology, Leiden University Medical Center, the Netherlands; 13Department of Gastroenterology and Hepatology, Maastricht University Medical Center, the Netherlands; 14Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands; 15Department of Gastroenterology and Hepatology, Meander Medical Center, Amersfoort, the Netherlands; and 16Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands.

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September 2017

Long-Term Clinical Outcomes After Switching from Remicade to Biosimilar CT-P13 in Inflammatory Bowel Disease.

Dig Dis Sci 2017 11 30;62(11):3117-3122. Epub 2017 Jun 30.

Inflammatory Bowel Disease Center, Department of Gastroenterology and Hepatology, Radboud University Medical Center, PO Box 9101, Code 455, 6500 HB, Nijmegen, The Netherlands.

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November 2017

More Dose-dependent Side Effects with Mercaptopurine over Azathioprine in IBD Treatment Due to Relatively Higher Dosing.

Inflamm Bowel Dis 2017 10;23(10):1873-1881

Departments of *Gastroenterology, †Human Genetics, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands; ‡Department of Clinical Pharmacy, Pharmacology and Toxicology, Zuyderland Medical Center, Sittard-Geleen, the Netherlands; §Department for Health Evidence, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands; ‖Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht University, Utrecht, the Netherlands; ¶Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, the Netherlands; and **Department of Clinical Pharmacy, Máxima Medical Center, Veldhoven, the Netherlands.

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October 2017

Clinical Outcomes Following a Switch from Remicade® to the Biosimilar CT-P13 in Inflammatory Bowel Disease Patients: A Prospective Observational Cohort Study.

J Crohns Colitis 2016 Nov 19;10(11):1287-1293. Epub 2016 Apr 19.

Inflammatory Bowel Disease Centre, Department of Gastroenterology and Hepatology, Radboud university medical centre, Nijmegen, The Netherlands

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November 2016

The Prevalence of Nodular Regenerative Hyperplasia in Inflammatory Bowel Disease Patients Treated with Thioguanine Is Not Associated with Clinically Significant Liver Disease.

Inflamm Bowel Dis 2016 09;22(9):2112-20

*Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, the Netherlands; †Department of Pathology, Academic Medical Center, Amsterdam, the Netherlands; ‡Department of Gastroenterology and Hepatology, Rijnstate Hospital, Arnhem, the Netherlands; §Department of Gastroenterology and Hepatology, Isala Klinieken, Zwolle, the Netherlands; ‖Department of Gastroenterology and Hepatology, St Antonius Hospital, Nieuwegein, the Netherlands; ¶Department of Gastroenterology and Hepatology, Medical Spectrum Twente, Enschede, the Netherlands; **Department of Internal Medicine, Gastroenterology and Geriatrics, Atrium-Orbis Medical Center, Heerlen-Sittard-Geleen, the Netherlands; ††Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands; Departments of ‡‡Epidemiology and Biostatistics, and §§Pathology, VU University Medical Center, Amsterdam, the Netherlands.

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September 2016

LPS-Stimulated Whole Blood Cytokine Production Is Not Related to Disease Behavior in Patients with Quiescent Crohn's Disease.

PLoS One 2015 24;10(7):e0133932. Epub 2015 Jul 24.

Department of Gastroenterology & Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.

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May 2016

Identification of Patients With Variants in TPMT and Dose Reduction Reduces Hematologic Events During Thiopurine Treatment of Inflammatory Bowel Disease.

Gastroenterology 2015 Oct 11;149(4):907-17.e7. Epub 2015 Jun 11.

Department of Human Genetics, Donders Centre for Neuroscience, Radboud university medical center, Nijmegen, The Netherlands; Department of Psychiatry, Donders Centre for Neuroscience, Radboud university medical center, Nijmegen, The Netherlands.

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October 2015

Allopurinol and 5-aminosalicylic acid influence thiopurine-induced hepatotoxicity in vitro.

Cell Biol Toxicol 2015 Jun 28;31(3):161-71. Epub 2015 Apr 28.

Department of Gastroenterology, Radboud University Nijmegen Medical Center, 455, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands,

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June 2015

Epstein-Barr virus in inflammatory bowel disease: the spectrum of intestinal lymphoproliferative disorders.

J Crohns Colitis 2015 May 4;9(5):398-403. Epub 2015 Mar 4.

Inflammatory Bowel Disease Center, Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, The Netherlands.

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May 2015

Self-reported disability in patients with inflammatory bowel disease largely determined by disease activity and illness perceptions.

Inflamm Bowel Dis 2015 Feb;21(2):369-77

1Department of Gastroenterology and Hepatology, University Medical Center Utrecht, the Netherlands; 2Medical Psychology Section, Leiden University Medical Center, Leiden, the Netherlands; 3Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, the Netherlands; 4Department of Gastroenterology and Hepatology, Orbis Medical Center, Sittard, the Netherlands; 5Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, the Netherlands; 6University of Groningen, Groningen, the Netherlands; 7Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands; 8Division of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, the Netherlands; 9Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands; 10Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands; 11Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands; 12Department of Gastroenterology and Hepatology, Slingeland Hospital, Doetinchem, the Netherlands; 13Department of Gastroenterology and Hepatology, Diaconessenhuis, Leiden, the Netherlands; 14Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands; 15Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, the Netherlands; 16Department of Gastroenterology and Hepatology, Reinier de Graaf Groep, Delft, the Netherlands; and 17Department of Gastroenterology and Hepatology, Meander Medical Center, Amersfoort, the Netherlands.

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February 2015

Recognition of Streptococcus pneumoniae and muramyl dipeptide by NOD2 results in potent induction of MMP-9, which can be controlled by lipopolysaccharide stimulation.

Infect Immun 2014 Dec 2;82(12):4952-8. Epub 2014 Sep 2.

Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud University Medical Center, Nijmegen, The Netherlands Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

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December 2014

Myosin IXb variants and their pivotal role in maintaining the intestinal barrier: a study in Crohn's disease.

Scand J Gastroenterol 2014 Oct 6;49(10):1191-200. Epub 2014 Aug 6.

Department of Gastroenterology and Hepatology, Charité, Campus Mitte, Universitätsmedizin Berlin , Berlin , Germany.

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October 2014

Effect of aging on healthcare costs of inflammatory bowel disease: a glimpse into the future.

Inflamm Bowel Dis 2014 Apr;20(4):637-45

1Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, the Netherlands 2Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands; 3Agis Health Insurance, Amersfoort, the Netherlands; 4Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, the Netherlands; 5Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, the Netherlands; 6Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands; 7Department of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, the Netherlands; 8Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands; 9Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands; 10Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands; 11Department of Gastroenterology and Hepatology, Slingeland Hospital, Doetinchem, the Netherlands; 12Department of Gastroenterology and Hepatology, Orbis Medical Center, Sittard, the Netherlands; 13Department of Gastroenterology and Hepatology, Diaconessenhuis, Leiden, the Netherlands; 14Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands; 15Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, the Netherlands; 16Department of Gastroenterology and Hepatology, Reinier de Graaf Groep, Delft, the Netherlands; and 17Department of Gastroenterology and Hepatology, Meander Medical Center, Amersfoort, the Netherlands.

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April 2014

Prior colorectal neoplasia is associated with increased risk of ileoanal pouch neoplasia in patients with inflammatory bowel disease.

Gastroenterology 2014 Jan 25;146(1):119-28.e1. Epub 2013 Sep 25.

Inflammatory Bowel Disease Center, Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. Electronic address:

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January 2014

Elective switching from infliximab to adalimumab in stable Crohn's disease.

Inflamm Bowel Dis 2013 Mar-Apr;19(4):761-6

Inflammatory Bowel Disease Center , Radboud University Medical Center, Nijmegen, The Netherlands.

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September 2013

Respiratory syncytial virus infection augments NOD2 signaling in an IFN-β-dependent manner in human primary cells.

Eur J Immunol 2012 Oct 20;42(10):2727-35. Epub 2012 Aug 20.

Department of Pediatrics, Radboud University Medical Centre, Nijmegen, Netherlands.

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October 2012

Infliximab exerts no direct hepatotoxic effect on HepG2 cells in vitro.

Dig Dis Sci 2012 Jun 26;57(6):1604-8. Epub 2012 Apr 26.

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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June 2012

High mucosal healing rates in 5-ASA-treated ulcerative colitis patients: results of a meta-analysis of clinical trials.

Inflamm Bowel Dis 2012 Nov 14;18(11):2190-8. Epub 2012 Mar 14.

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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November 2012

A functional polymorphism in UGT1A1 related to hyperbilirubinemia is associated with a decreased risk for Crohn's disease.

J Crohns Colitis 2012 Jun 16;6(5):597-602. Epub 2011 Dec 16.

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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June 2012

HNF4α and CDH1 are associated with ulcerative colitis in a Dutch cohort.

Inflamm Bowel Dis 2011 Aug 28;17(8):1714-8. Epub 2010 Nov 28.

Department of Genetics, University Medical Center Groningen, The Netherlands.

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August 2011

High prevalence of fatigue in inflammatory bowel disease: A case control study.

J Crohns Colitis 2011 Aug 24;5(4):332-7. Epub 2011 Mar 24.

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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August 2011

Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2.

Gut 2011 Sep 15;60(9):1229-35. Epub 2011 Mar 15.

Department of Medicine, Radboud University, Nijmegen Medical Centre, Internal postal code 463, P.O. Box 9101, Geert Grooteplein 8, 6500 HB Nijmegen, The Netherlands.

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September 2011

Effect of childbirth on the course of Crohn's disease; results from a retrospective cohort study in the Netherlands.

BMC Gastroenterol 2011 Jan 26;11. Epub 2011 Jan 26.

Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, PO box 9101, 6500 HB, Nijmegen, The Netherlands.

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January 2011

The functional -765G→C polymorphism of the COX-2 gene may reduce the risk of developing crohn's disease.

PLoS One 2010 Nov 24;5(11):e15011. Epub 2010 Nov 24.

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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November 2010

Recognition of Borrelia burgdorferi by NOD2 is central for the induction of an inflammatory reaction.

J Infect Dis 2010 Jun;201(12):1849-58

Department of Medicine, Nijmegen Institute of Infection, Inflammation, and Immunity, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.

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June 2010

Serious events with infliximab in patients with inflammatory bowel disease: a 9-year cohort study in the Netherlands.

Drug Saf 2008 ;31(12):1135-44

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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March 2009

Crohn's disease patients homozygous for the 3020insC NOD2 mutation have a defective NOD2/TLR4 cross-tolerance to intestinal stimuli.

Immunology 2008 Apr 20;123(4):600-5. Epub 2007 Nov 20.

Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, and Nijmegen University Center for Infectious Diseases, Nijmegen, The Netherlands.

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April 2008

Mycobacterium paratuberculosis is recognized by Toll-like receptors and NOD2.

J Leukoc Biol 2007 Oct 25;82(4):1011-8. Epub 2007 Jul 25.

Department of Internal Medicine and Nijmegen University Center for Infectious Diseases, Radboud University Nijmegen Medical Center, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, The Netherlands.

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October 2007

Potential role of pharmacogenetics in anti-TNF treatment of rheumatoid arthritis and Crohn's disease.

Drug Discov Today 2007 Feb 4;12(3-4):125-31. Epub 2006 Dec 4.

Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, PO Box 9600, NL 2300 RC Leiden, The Netherlands.

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February 2007

Impaired dendritic cell function in Crohn's disease patients with NOD2 3020insC mutation.

J Leukoc Biol 2006 Apr 3;79(4):860-6. Epub 2006 Feb 3.

Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Geert Grooteplein 28, 6525 GA, Nijmegen, The Netherlands.

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April 2006

Protective effect of nonsteroidal anti-inflammatory drugs on colorectal adenomas is modified by a polymorphism in peroxisome proliferator-activated receptor delta.

Pharmacogenet Genomics 2006 Jan;16(1):43-50

Department of Toxicology Pathology and Genetics, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

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January 2006

Side effects of azathioprine in patients with Crohn's disease.

Eur J Gastroenterol Hepatol 2004 Feb;16(2):207-12

Department of Gastroenterology and Hepatology, University Medical Centre Nijmegen, The Netherlands.

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February 2004