Publications by authors named "Dirk J Slotboom"

25Publications

Bacterial multi-solute transporters.

FEBS Lett 2020 Aug 18. Epub 2020 Aug 18.

Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1002/1873-3468.13912DOI Listing
August 2020

An ECF-type transporter scavenges heme to overcome iron-limitation in .

Elife 2020 Jun 9;9. Epub 2020 Jun 9.

Interfaculty Institute of Microbiology and Infection Medicine, Department of Infection Biology, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.7554/eLife.57322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299338PMC
June 2020

Elevator-type mechanisms of membrane transport.

Biochem Soc Trans 2020 06;48(3):1227-1241

Groningen Biomolecular Sciences and Biotechnology Institute, Membrane Enzymology, University of Groningen, The Netherlands.

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http://dx.doi.org/10.1042/BST20200290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329351PMC
June 2020

Membrane mediated toppling mechanism of the folate energy coupling factor transporter.

Nat Commun 2020 04 9;11(1):1763. Epub 2020 Apr 9.

University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.

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http://dx.doi.org/10.1038/s41467-020-15554-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145868PMC
April 2020

Structural ensemble of a glutamate transporter homologue in lipid nanodisc environment.

Nat Commun 2020 02 21;11(1):998. Epub 2020 Feb 21.

Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 4, 9747AG, Groningen, The Netherlands.

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http://dx.doi.org/10.1038/s41467-020-14834-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035293PMC
February 2020

Molecular insight into a new low-affinity xylan binding module from the xylanolytic gut symbiont Roseburia intestinalis.

FEBS J 2020 May 20;287(10):2105-2117. Epub 2019 Nov 20.

Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.

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http://dx.doi.org/10.1111/febs.15117DOI Listing
May 2020

A one-gate elevator mechanism for the human neutral amino acid transporter ASCT2.

Nat Commun 2019 07 31;10(1):3427. Epub 2019 Jul 31.

Membrane Enzymology, University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute, Groningen, The Netherlands.

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http://dx.doi.org/10.1038/s41467-019-11363-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668440PMC
July 2019

Binding and transport of D-aspartate by the glutamate transporter homolog Glt.

Elife 2019 04 10;8. Epub 2019 Apr 10.

Groningen Biomolecular Sciences and Biotechnology Institute, Zernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands.

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https://elifesciences.org/articles/45286
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http://dx.doi.org/10.7554/eLife.45286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482001PMC
April 2019

Models to determine the kinetic mechanisms of ion-coupled transporters.

J Gen Physiol 2019 03 10;151(3):369-380. Epub 2019 Jan 10.

Membrane Enzymology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands

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http://dx.doi.org/10.1085/jgp.201812055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400521PMC
March 2019

Cryo-EM structure of the human neutral amino acid transporter ASCT2.

Nat Struct Mol Biol 2018 06 5;25(6):515-521. Epub 2018 Jun 5.

University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute, Membrane Enzymology, Groningen, the Netherlands.

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http://dx.doi.org/10.1038/s41594-018-0076-yDOI Listing
June 2018

Functional and structural characterization of an ECF-type ABC transporter for vitamin B12.

Elife 2018 05 29;7. Epub 2018 May 29.

Groningen Biomolecular and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.7554/eLife.35828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997447PMC
May 2018

The structural basis of proton driven zinc transport by ZntB.

Nat Commun 2017 11 3;8(1):1313. Epub 2017 Nov 3.

Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747AG, Groningen, The Netherlands.

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http://dx.doi.org/10.1038/s41467-017-01483-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670123PMC
November 2017

Dynamic Combinatorial Chemistry to Identify Binders of ThiT, an S-Component of the Energy-Coupling Factor Transporter for Thiamine.

ChemMedChem 2017 10 6;12(20):1693-1696. Epub 2017 Oct 6.

Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 7, 9747, AG, Groningen, The Netherlands.

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http://dx.doi.org/10.1002/cmdc.201700440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698757PMC
October 2017

Single-Molecule Fluorescence Studies of Membrane Transporters Using Total Internal Reflection Microscopy.

Methods Enzymol 2017 18;594:101-121. Epub 2017 Jul 18.

University of Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2017.05.009DOI Listing
January 2018

Structural insight in the toppling mechanism of an energy-coupling factor transporter.

Nat Commun 2016 Mar 30;7:11072. Epub 2016 Mar 30.

Groningen Biomolecular Science and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1038/ncomms11072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820897PMC
March 2016

Competition between Different S-Components for the Shared Energy Coupling Factor Module in Energy Coupling Factor Transporters.

Biochemistry 2015 Aug 30;54(31):4763-6. Epub 2015 Jul 30.

†Department of Biochemistry, University of Groningen, Groningen Biomolecular Science and Biotechnology Institute, Nijenborg 4, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1021/acs.biochem.5b00609DOI Listing
August 2015

Structure-based design of potent small-molecule binders to the S-component of the ECF transporter for thiamine.

Chembiochem 2015 Mar 12;16(5):819-26. Epub 2015 Feb 12.

Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen (The Netherlands) http://www.rug.nl/research/membrane-enzymology/

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http://doi.wiley.com/10.1002/cbic.201402673
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http://dx.doi.org/10.1002/cbic.201402673DOI Listing
March 2015

Structural and mechanistic insights into prokaryotic energy-coupling factor transporters.

Authors:
Dirk J Slotboom

Nat Rev Microbiol 2014 02 23;12(2):79-87. Epub 2013 Dec 23.

University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for advanced Materials, Groningen, The Netherlands.

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http://www.nature.com/articles/nrmicro3175
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http://dx.doi.org/10.1038/nrmicro3175DOI Listing
February 2014

Genomic distribution of the small multidrug resistance protein EmrE over 29 Escherichia coli strains reveals two forms of the protein.

FEBS J 2013 Jan 11;280(1):244-55. Epub 2012 Dec 11.

Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/febs.12065DOI Listing
January 2013

The yeast vacuolar membrane proteome.

Mol Cell Proteomics 2009 Feb 10;8(2):380-92. Epub 2008 Nov 10.

Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1074/mcp.M800372-MCP200DOI Listing
February 2009

Tuning Escherichia coli for membrane protein overexpression.

Proc Natl Acad Sci U S A 2008 Sep 16;105(38):14371-6. Epub 2008 Sep 16.

Center for Biomembrane Research, Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.0804090105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567230PMC
September 2008

Identification of genes encoding the folate- and thiamine-binding membrane proteins in Firmicutes.

J Bacteriol 2008 Nov 5;190(22):7591-4. Epub 2008 Sep 5.

Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA.

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http://dx.doi.org/10.1128/JB.01070-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576666PMC
November 2008