Dirk Hockemeyer

Dirk Hockemeyer

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Dirk Hockemeyer

Dirk Hockemeyer

Publications by authors named "Dirk Hockemeyer"

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42Publications

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Genetically engineered human cortical spheroid models of tuberous sclerosis.

Nat Med 2018 10 20;24(10):1568-1578. Epub 2018 Aug 20.

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.

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http://www.nature.com/articles/s41591-018-0139-y
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http://dx.doi.org/10.1038/s41591-018-0139-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261470PMC
October 2018

Widespread Translational Remodeling during Human Neuronal Differentiation.

Cell Rep 2017 Nov;21(7):2005-2016

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.10.095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759054PMC
November 2017

Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System.

Stem Cell Reports 2017 06 25;8(6):1770-1783. Epub 2017 May 25.

Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94720-1762, USA; Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720-1462, USA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720-3370, USA; The Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720-3370, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.04.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470111PMC
June 2017

Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo.

Mol Cell Biol 2017 02 19;37(3). Epub 2017 Jan 19.

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA

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http://dx.doi.org/10.1128/MCB.00541-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247607PMC
February 2017

Induced Pluripotent Stem Cells Meet Genome Editing.

Cell Stem Cell 2016 05;18(5):573-86

The Whitehead Institute for Biomedical Research and Department of Biology, MIT, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1016/j.stem.2016.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871596PMC
May 2016

Establishment of Genome-edited Human Pluripotent Stem Cell Lines: From Targeting to Isolation.

J Vis Exp 2016 Feb 2(108):e53583. Epub 2016 Feb 2.

Department of Molecular and Cell Biology, University of California, Berkeley;

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http://dx.doi.org/10.3791/53583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781717PMC
February 2016

Human stem cell-based disease modeling: prospects and challenges.

Curr Opin Cell Biol 2015 Dec 11;37:84-90. Epub 2015 Nov 11.

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ceb.2015.10.007DOI Listing
December 2015

Control of telomerase action at human telomeres.

Nat Struct Mol Biol 2015 Nov;22(11):848-52

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA.

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http://dx.doi.org/10.1038/nsmb.3083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765361PMC
November 2015

Genome editing in human pluripotent stem cells using site-specific nucleases.

Methods Mol Biol 2015 ;1239:267-80

Department of Molecular and Cell Biology, University of California, Berkeley, 400B Li Ka Shing Center, Berkeley, CA, 94720-3370, USA.

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http://dx.doi.org/10.1007/978-1-4939-1862-1_15DOI Listing
July 2015

Cancer-associated TERT promoter mutations abrogate telomerase silencing.

Elife 2015 Jul 21;4. Epub 2015 Jul 21.

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.

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http://dx.doi.org/10.7554/eLife.07918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507476PMC
July 2015

TALEN gene knockouts reveal no requirement for the conserved human shelterin protein Rap1 in telomere protection and length regulation.

Cell Rep 2014 Nov 6;9(4):1273-80. Epub 2014 Nov 6.

Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254571PMC
November 2014

Genome editing 101: let's go digital.

Nat Methods 2014 Mar;11(3):248-9

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA.

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http://dx.doi.org/10.1038/nmeth.2859DOI Listing
March 2014

Transgene excision has no impact on in vivo integration of human iPS derived neural precursors.

PLoS One 2011 22;6(9):e24687. Epub 2011 Sep 22.

Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024687PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178523PMC
March 2012

Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression.

Proc Natl Acad Sci U S A 2011 Nov 19;108(44):18061-6. Epub 2011 Oct 19.

Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1073/pnas.1114946108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207684PMC
November 2011

Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.

Cell 2009 Jul;138(1):90-103

Laboratory for Cell Biology and Genetics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.cell.2009.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723738PMC
July 2009

Functional dissection of human and mouse POT1 proteins.

Mol Cell Biol 2009 Jan 27;29(2):471-82. Epub 2008 Oct 27.

Laboratory for Cell Biology and Genetics, The Rockefeller University, 1230 York Avenue, New York, NY 10065-6399, USA.

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http://delangelab.rockefeller.edu/pubs/110_Palm_MCB2008.pdf
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http://mcb.asm.org/cgi/doi/10.1128/MCB.01352-08
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http://dx.doi.org/10.1128/MCB.01352-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612509PMC
January 2009

Engineered telomere degradation models dyskeratosis congenita.

Genes Dev 2008 Jul 11;22(13):1773-85. Epub 2008 Jun 11.

Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, New York 10065, USA.

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http://dx.doi.org/10.1101/gad.1679208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2492664PMC
July 2008

Telomere protection by mammalian Pot1 requires interaction with Tpp1.

Nat Struct Mol Biol 2007 Aug 15;14(8):754-61. Epub 2007 Jul 15.

Laboratory for Cell Biology and Genetics, The Rockefeller University, 1230 York Avenue, New York, New York 10065, USA.

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http://delangelab.rockefeller.edu/pubs/100_Hockemeyer_NSMB_2
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http://www.nature.com/doifinder/10.1038/nsmb1270
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http://dx.doi.org/10.1038/nsmb1270DOI Listing
August 2007

Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres.

Cell 2006 Jul;126(1):63-77

Laboratory for Cell Biology and Genetics, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.cell.2006.04.044DOI Listing
July 2006

POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end.

EMBO J 2005 Jul 23;24(14):2667-78. Epub 2005 Jun 23.

Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, NY 10021, USA.

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http://dx.doi.org/10.1038/sj.emboj.7600733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1176460PMC
July 2005

POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex.

Genes Dev 2004 Jul 1;18(14):1649-54. Epub 2004 Jul 1.

Laboratory for Cell Biology and Genetics and Laboratory for Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, New York 10021, USA.

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http://dx.doi.org/10.1101/gad.1215404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC478187PMC
July 2004

SRF regulates Bcl-2 expression and promotes cell survival during murine embryonic development.

EMBO J 2004 Apr 1;23(8):1834-44. Epub 2004 Apr 1.

Interfakultäres Institut für Zellbiologie, Abteilung Molekularbiologie, Universität Tübingen, Auf der Morgenstelle, Tübingen, Germany.

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http://dx.doi.org/10.1038/sj.emboj.7600188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC394242PMC
April 2004

Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression.

Nature 2004 Mar;428(6979):185-9

Department of Molecular Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, Texas 75390-9148, USA.

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http://dx.doi.org/10.1038/nature02382DOI Listing
March 2004

Potentiation of serum response factor activity by a family of myocardin-related transcription factors.

Proc Natl Acad Sci U S A 2002 Nov 23;99(23):14855-60. Epub 2002 Oct 23.

Department of Molecular Biology, University of Texas, Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas 75390-9148, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.222561499
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http://dx.doi.org/10.1073/pnas.222561499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137508PMC
November 2002