Dirk Foell

Dirk Foell

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Dirk Foell

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Authors:
Claas H Hinze Dirk Foell

Arthritis Rheumatol 2019 Nov 25;71(11):1969-1970. Epub 2019 Sep 25.

University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1002/art.41021DOI Listing
November 2019

Synergistic TLR/IFNα/β-Signaling Facilitates Escape of IL-18 Expression from Endotoxin Tolerance.

Authors:
Emely Verweyen Dirk Holzinger Toni Weinhage Claas Hinze Helmut Wittkowski Peter Pickkers Sabrin Albeituni Katherine Verbist Kim E Nichols Grant Schulert Alexei Grom Dirk Foell Christoph Kessel

Am J Respir Crit Care Med 2019 Nov 11. Epub 2019 Nov 11.

University Hospital Munster, 39069, Pediatric Rheumatology and Immunology, Muenster, Germany;

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http://dx.doi.org/10.1164/rccm.201903-0659OCDOI Listing
November 2019

Identification of Novel Adenosine Deaminase 2 Gene Variants and Varied Clinical Phenotype in Pediatric Vasculitis.

Authors:
Kristen M Gibson Kimberly A Morishita Paul Dancey Paul Moorehead Britt Drögemöller Xiaohua Han Jinko Graham Robert E W Hancock Dirk Foell Susanne Benseler Rashid Luqmani Rae S M Yeung Susan Shenoi Marek Bohm Alan M Rosenberg Colin J Ross David A Cabral Kelly L Brown

Arthritis Rheumatol 2019 Oct 26;71(10):1747-1755. Epub 2019 Aug 26.

University of British Columbia and BC Children's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/art.40913DOI Listing
October 2019

Impact of IL1RN variants on response to interleukin-1 blocking therapy in systemic juvenile idiopathic arthritis.

Authors:
Claas Hinze Sabrina Fuehner Christoph Kessel Helmut Wittkowski Elke Lainka Melanie Baehr Boris Hügle Johannes-Peter Haas Gerd Ganser Elisabeth Weißbarth-Riedel Annette Jansson Dirk Foell

Arthritis Rheumatol 2019 Oct 10. Epub 2019 Oct 10.

Department of Pediatric Rheumatology and Immunology, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1002/art.41130DOI Listing
October 2019

Innately adaptive or truly autoimmune.

Authors:
Christoph Kessel Christian M Hedrich Dirk Foell

Arthritis Rheumatol 2019 Sep 16. Epub 2019 Sep 16.

Department of Pediatric Rheumatology and Immunology, University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/art.41107DOI Listing
September 2019

Tofacitinib Reprograms Human Monocytes of IBD Patients and Healthy Controls Toward a More Regulatory Phenotype.

Authors:
Friederike Cordes Eva Lenker Lea J Spille Toni Weinhage Dominik Bettenworth Christoph Kessel Hartmut H Schmidt Dirk Foell Georg Varga

Inflamm Bowel Dis 2019 Sep 27. Epub 2019 Sep 27.

Department of Pediatric Rheumatology and Immunology, University Children's Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1093/ibd/izz213DOI Listing
September 2019

Purification of Human S100A12 and Its Ion-induced Oligomers for Immune Cell Stimulation.

Authors:
Sabrina Fuehner Dirk Foell Christoph Kessel

J Vis Exp 2019 Sep 29(151). Epub 2019 Sep 29.

Department of Pediatric Rheumatology and Immunology, University Children's Hospital;

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http://dx.doi.org/10.3791/60065DOI Listing
September 2019

Molecular signature characterisation of different inflammatory phenotypes of systemic juvenile idiopathic arthritis.

Authors:
Faekah Gohar Angela McArdle Melissa Jones Niamh Callan Belinda Hernandez Christoph Kessel Maria Miranda-Garcia Miha Lavric Dirk Holzinger Carolin Pretzer Elke Lainka Sebastiaan J Vastert Sytze de Roock Oliver FitzGerald Stephen R Pennington Dirk Foell

Ann Rheum Dis 2019 Aug 20;78(8):1107-1113. Epub 2019 Apr 20.

Department of Paediatric Rheumatology and Immunology, University of Münster, Münster, Germany

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2019-21505
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http://dx.doi.org/10.1136/annrheumdis-2019-215051DOI Listing
August 2019

Classification criteria for autoinflammatory recurrent fevers.

Authors:
Marco Gattorno Michael Hofer Silvia Federici Federica Vanoni Francesca Bovis Ivona Aksentijevich Jordi Anton Juan Ignacio Arostegui Karyl Barron Eldad Ben-Cherit Paul A Brogan Luca Cantarini Isabella Ceccherini Fabrizio De Benedetti Fatma Dedeoglu Erkan Demirkaya Joost Frenkel Raphaela Goldbach-Mansky Ahmet Gul Veronique Hentgen Hal Hoffman Tilmann Kallinich Isabelle Kone-Paut Jasmin Kuemmerle-Deschner Helen J Lachmann Ronald M Laxer Avi Livneh Laura Obici Seza Ozen Dorota Rowczenio Ricardo Russo Yael Shinar Anna Simon Nataša Toplak Isabelle Touitou Yosef Uziel Marielle van Gijn Dirk Foell Claudia Garassino Dan Kastner Alberto Martini Maria Pia Sormani Nicolino Ruperto

Ann Rheum Dis 2019 Aug 24;78(8):1025-1032. Epub 2019 Apr 24.

Clinica Pediatrica e Reumatologia, PRINTO, IRCCS Istituto Giannina Gaslini, Genoa, Italy.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2019-21504
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http://dx.doi.org/10.1136/annrheumdis-2019-215048DOI Listing
August 2019

S100A9 extends lifespan in insulin deficiency.

Authors:
Giorgio Ramadori Sanda Ljubicic Serena Ricci Despoina Mikropoulou Xavier Brenachot Christelle Veyrat-Durebex Ebru Aras Rafael M Ioris Jordi Altirriba Elisabeth Malle Dirk Foell Thomas Vogl Roberto Coppari

Nat Commun 2019 08 7;10(1):3545. Epub 2019 Aug 7.

Diabetes Center of the Faculty of Medicine, University of Geneva, 1211 Geneva 4, Geneva, Switzerland.

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http://dx.doi.org/10.1038/s41467-019-11498-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686003PMC
August 2019

Treatment to Target Using Recombinant Interleukin-1 Receptor Antagonist as First-Line Monotherapy in New-Onset Systemic Juvenile Idiopathic Arthritis: Results From a Five-Year Follow-Up Study.

Authors:
Nienke M Ter Haar E H Pieter van Dijkhuizen Joost F Swart Annet van Royen-Kerkhof Ayman El Idrissi Arjen P Leek Wilco de Jager Mark C H de Groot Saskia Haitjema Dirk Holzinger Dirk Foell Jorg van Loosdregt Nico M Wulffraat Sytze de Roock Sebastiaan J Vastert

Arthritis Rheumatol 2019 Jul 25;71(7):1163-1173. Epub 2019 May 25.

University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/art.40865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617757PMC
July 2019

The German National Registry of Primary Immunodeficiencies (2012-2017).

Authors:
Sabine M El-Helou Anika-Kerstin Biegner Sebastian Bode Stephan R Ehl Maximilian Heeg Maria E Maccari Henrike Ritterbusch Carsten Speckmann Stephan Rusch Raphael Scheible Klaus Warnatz Faranaz Atschekzei Renata Beider Diana Ernst Stev Gerschmann Alexandra Jablonka Gudrun Mielke Reinhold E Schmidt Gesine Schürmann Georgios Sogkas Ulrich H Baumann Christian Klemann Dorothee Viemann Horst von Bernuth Renate Krüger Leif G Hanitsch Carmen M Scheibenbogen Kirsten Wittke Michael H Albert Anna Eichinger Fabian Hauck Christoph Klein Anita Rack-Hoch Franz M Sollinger Anne Avila Michael Borte Stephan Borte Maria Fasshauer Anja Hauenherm Nils Kellner Anna H Müller Anett Ülzen Peter Bader Shahrzad Bakhtiar Jae-Yun Lee Ursula Heß Ralf Schubert Sandra Wölke Stefan Zielen Sujal Ghosh Hans-Juergen Laws Jennifer Neubert Prasad T Oommen Manfred Hönig Ansgar Schulz Sandra Steinmann Klaus Schwarz Gregor Dückers Beate Lamers Vanessa Langemeyer Tim Niehues Sonu Shai Dagmar Graf Carmen Müglich Marc T Schmalzing Eva C Schwaneck Hans-Peter Tony Johannes Dirks Gabriele Haase Johannes G Liese Henner Morbach Dirk Foell Antje Hellige Helmut Wittkowski Katja Masjosthusmann Michael Mohr Linda Geberzahn Christian M Hedrich Christiane Müller Angela Rösen-Wolff Joachim Roesler Antje Zimmermann Uta Behrends Nikolaus Rieber Uwe Schauer Rupert Handgretinger Ursula Holzer Jörg Henes Lothar Kanz Christoph Boesecke Jürgen K Rockstroh Carolynne Schwarze-Zander Jan-Christian Wasmuth Dagmar Dilloo Brigitte Hülsmann Stefan Schönberger Stefan Schreiber Rainald Zeuner Tobias Ankermann Philipp von Bismarck Hans-Iko Huppertz Petra Kaiser-Labusch Johann Greil Donate Jakoby Andreas E Kulozik Markus Metzler Nora Naumann-Bartsch Bettina Sobik Norbert Graf Sabine Heine Robin Kobbe Kai Lehmberg Ingo Müller Friedrich Herrmann Gerd Horneff Ariane Klein Joachim Peitz Nadine Schmidt Stefan Bielack Ute Groß-Wieltsch Carl F Classen Jessica Klasen Peter Deutz Dirk Kamitz Lisa Lassay Klaus Tenbrock Norbert Wagner Benedikt Bernbeck Bastian Brummel Eusebia Lara-Villacanas Esther Münstermann Dominik T Schneider Nadine Tietsch Marco Westkemper Michael Weiß Christof Kramm Ingrid Kühnle Silke Kullmann Hermann Girschick Christof Specker Elisabeth Vinnemeier-Laubenthal Henriette Haenicke Claudia Schulz Lothar Schweigerer Thomas G Müller Martina Stiefel Bernd H Belohradsky Veronika Soetedjo Gerhard Kindle Bodo Grimbacher

Front Immunol 2019 19;10:1272. Epub 2019 Jul 19.

Institute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.01272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659583PMC
July 2019

Predictive factors and biomarkers for the 2-year outcome of uveitis in juvenile idiopathic arthritis: data from the Inception Cohort of Newly diagnosed patients with Juvenile Idiopathic Arthritis (ICON-JIA) study.

Authors:
Arnd Heiligenhaus Jens Klotsche Christoph Tappeiner Claudia Sengler Martina Niewerth Ina Liedmann Sabine Hoeft Karoline Walscheid Miha Lavric Dirk Foell Kirsten Minden

Rheumatology (Oxford) 2019 Jun;58(6):975-986

German Rheumatism Research Center, a Leibniz Institute, Berlin.

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http://dx.doi.org/10.1093/rheumatology/key406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532445PMC
June 2019

Monocyte-Derived Interleukin-1β As the Driver of S100A12-Induced Sterile Inflammatory Activation of Human Coronary Artery Endothelial Cells: Implications for the Pathogenesis of Kawasaki Disease.

Authors:
Giulia Armaroli Emely Verweyen Carolin Pretzer Katharina Kessel Keiichi Hirono Fukiko Ichida Mako Okabe David A Cabral Dirk Foell Kelly L Brown Christoph Kessel

Arthritis Rheumatol 2019 May 25;71(5):792-804. Epub 2019 Mar 25.

University Children's Hospital, Munster, Germany.

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http://doi.wiley.com/10.1002/art.40784
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http://dx.doi.org/10.1002/art.40784DOI Listing
May 2019

Phenotypic variability and disparities in treatment and outcomes of childhood arthritis throughout the world: an observational cohort study.

Authors:
Alessandro Consolaro Gabriella Giancane Alessandra Alongi Evert Hendrik Pieter van Dijkhuizen Amita Aggarwal Sulaiman M Al-Mayouf Francesca Bovis Jaime De Inocencio Erkan Demirkaya Berit Flato Dirk Foell Stella Maris Garay Călin Lazăr Daniel J Lovell Carolina Montobbio Paivi Miettunen Dimitrina Mihaylova Susan Nielsen Ilonka Orban Ingrida Rumba-Rozenfelde Claudia Saad Magalhães Nahid Shafaie Gordana Susic Maria Trachana Nico Wulffraat Angela Pistorio Alberto Martini Nicolino Ruperto Angelo Ravelli

Lancet Child Adolesc Health 2019 Apr 26;3(4):255-263. Epub 2019 Feb 26.

Clinic of Paediatrics and Rheumatology, IRCCS Istituto Giannina Gaslini, University of Genoa, Genoa, Italy; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, and Maternal and Child Sciences, University of Genoa, Genoa, Italy. Electronic address:

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http://dx.doi.org/10.1016/S2352-4642(19)30027-6DOI Listing
April 2019

Serum S100A8/A9 and S100A12 Levels in Children With Polyarticular Forms of Juvenile Idiopathic Arthritis: Relationship to Maintenance of Clinically Inactive Disease During Anti-Tumor Necrosis Factor Therapy and Occurrence of Disease Flare After Discontinuation of Therapy.

Authors:
Claas H Hinze Dirk Foell Anne L Johnson Steven J Spalding Beth S Gottlieb Paula W Morris Yukiko Kimura Karen Onel Suzanne C Li Alexei A Grom Janalee Taylor Hermine I Brunner Jennifer L Huggins James J Nocton Kathleen A Haines Barbara S Edelheit Michael Shishov Lawrence K Jung Calvin B Williams Melissa S Tesher Denise M Costanzo Lawrence S Zemel Jason A Dare Murray H Passo Kaleo C Ede Judyann C Olson Elaine A Cassidy Thomas A Griffin Linda Wagner-Weiner Jennifer E Weiss Larry B Vogler Kelly A Rouster-Stevens Timothy Beukelman Randy Q Cron Daniel Kietz Kenneth Schikler Jay Mehta Tracy V Ting James W Verbsky Anne B Eberhard Bin Huang Edward H Giannini Daniel J Lovell

Arthritis Rheumatol 2019 03 24;71(3):451-459. Epub 2019 Jan 24.

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1002/art.40727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393224PMC
March 2019

Canakinumab in patients with systemic juvenile idiopathic arthritis and active systemic features: results from the 5-year long-term extension of the phase III pivotal trials.

Authors:
Nicolino Ruperto Hermine I Brunner Pierre Quartier Tamàs Constantin Nico M Wulffraat Gerd Horneff Ozgur Kasapcopur Rayfel Schneider Jordi Anton Judith Barash Reinhard Berner Fabrizia Corona Ruben Cuttica Marine Fouillet-Desjonqueres Michel Fischbach Helen E Foster Dirk Foell Sebastião C Radominski Athimalaipet V Ramanan Ralf Trauzeddel Erbil Unsal Jérémy Levy Eleni Vritzali Alberto Martini Daniel J Lovell

Ann Rheum Dis 2018 12 29;77(12):1710-1719. Epub 2018 Sep 29.

Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2018-21315
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http://dx.doi.org/10.1136/annrheumdis-2018-213150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241618PMC
December 2018

Vitamin D deficiency is associated with higher disease activity and the risk for uveitis in juvenile idiopathic arthritis - data from a German inception cohort.

Authors:
Claudia Sengler Julian Zink Jens Klotsche Martina Niewerth Ina Liedmann Gerd Horneff Christoph Kessel Gerd Ganser Angelika Thon Johannes-Peter Haas Anton Hospach Frank Weller-Heinemann Arnd Heiligenhaus Dirk Foell Angela Zink Kirsten Minden

Arthritis Res Ther 2018 12 13;20(1):276. Epub 2018 Dec 13.

German Rheumatism Research Center, a Leibniz Institute, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1186/s13075-018-1765-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293517PMC
December 2018

Evaluation of the S100 protein A12 as a biomarker of neonatal sepsis.

Authors:
Angie M S Tosson Kirsten Glaser Toni Weinhage Dirk Foell Mohamed S Aboualam Amira A Edris Mervat El Ansary Sohilla Lotfy Christian P Speer

J Matern Fetal Neonatal Med 2018 Dec 18:1-191. Epub 2018 Dec 18.

b University Children's Hospital , University of Würzburg , Würzburg , Germany.

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https://www.tandfonline.com/doi/full/10.1080/14767058.2018.1
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http://dx.doi.org/10.1080/14767058.2018.1560411DOI Listing
December 2018

S100A12 Serum Levels and PMN Counts Are Elevated in Childhood Systemic Vasculitides Especially Involving Proteinase 3 Specific Anti-neutrophil Cytoplasmic Antibodies.

Authors:
Kelly L Brown Joanna M Lubieniecka Giulia Armaroli Katharina Kessel Kristen M Gibson Jinko Graham Dongmeng Liu Robert E W Hancock Colin J Ross Susanne M Benseler Raashid A Luqmani David A Cabral Dirk Foell Christoph Kessel

Front Pediatr 2018 23;6:341. Epub 2018 Nov 23.

Department of Pediatric Rheumatology and Immunology, University Hospital Muenster, Muenster, Germany.

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https://www.frontiersin.org/article/10.3389/fped.2018.00341/
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http://dx.doi.org/10.3389/fped.2018.00341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266798PMC
November 2018

Serum S100 Proteins as a Marker of Disease Activity in Large Vessel Vasculitis.

Authors:
Jason Michael Springer Paul Monach David Cuthbertson Simon Carette Nader A Khalidi Carol A McAlear Christian Pagnoux Philip Seo Kenneth J Warrington Steven R Ytterberg Gary Hoffman Carol Langford Thomas Hamilton Dirk Foell Thomas Vogl Dirk Holzinger Peter A Merkel Johannes Roth Rula A Hajj-Ali

J Clin Rheumatol 2018 Oct;24(7):393-395

From the Department of Medicine, University of Kansas Medical Center, Kansas City, KS.

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http://dx.doi.org/10.1097/RHU.0000000000000729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105726PMC
October 2018

Risk Factors and Biomarkers for the Occurrence of Uveitis in Juvenile Idiopathic Arthritis: Data From the Inception Cohort of Newly Diagnosed Patients With Juvenile Idiopathic Arthritis Study.

Authors:
Christoph Tappeiner Jens Klotsche Claudia Sengler Martina Niewerth Ina Liedmann Karoline Walscheid Miha Lavric Dirk Foell Kirsten Minden Arnd Heiligenhaus

Arthritis Rheumatol 2018 10 21;70(10):1685-1694. Epub 2018 Aug 21.

St. Franziskus Hospital, Muenster, Germany.

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http://dx.doi.org/10.1002/art.40544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174956PMC
October 2018

Calcium and zinc tune autoinflammatory Toll-like receptor 4 signaling by S100A12.

Authors:
Christoph Kessel Sabrina Fuehner Jana Zell Bastian Zimmermann Stephan Drewianka Sonja Brockmeyer Dirk Holzinger Claas Hinze Helmut Wittkowski Dirk Foell

J Allergy Clin Immunol 2018 10 3;142(4):1370-1373.e8. Epub 2018 Jul 3.

Department of Pediatric Rheumatology and Immunology, University Children's Hospital, Muenster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.06.027DOI Listing
October 2018

The role of S100 proteins in the pathogenesis and monitoring of autoinflammatory diseases.

Authors:
Dirk Holzinger Dirk Foell Christoph Kessel

Mol Cell Pediatr 2018 Sep 25;5(1). Epub 2018 Sep 25.

Department of Pediatric Rheumatology and Immunology, University Children's Hospital Muenster, Domagkstr. 3, 48149, Muenster, Germany.

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http://dx.doi.org/10.1186/s40348-018-0085-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156694PMC
September 2018

IL1RN Variation Influences Both Disease Susceptibility and Response to Recombinant Human Interleukin-1 Receptor Antagonist Therapy in Systemic Juvenile Idiopathic Arthritis.

Authors:
Victoria L Arthur Emily Shuldiner Elaine F Remmers Anne Hinks Alexei A Grom Dirk Foell Alberto Martini Marco Gattorno Seza Özen Sampath Prahalad Andrew S Zeft John F Bohnsack Norman T Ilowite Elizabeth D Mellins Ricardo Russo Claudio Len Sheila Oliveira Rae S M Yeung Alan M Rosenberg Lucy R Wedderburn Jordi Anton Johannes-Peter Haas Angela Rösen-Wolff Kirsten Minden Ann Marie Szymanski Wendy Thomson Daniel L Kastner Patricia Woo Michael J Ombrello

Arthritis Rheumatol 2018 08 28;70(8):1319-1330. Epub 2018 Jun 28.

National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1002/art.40498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105455PMC
August 2018

Inherited p40phox deficiency differs from classic chronic granulomatous disease.

Authors:
Annemarie van de Geer Alejandro Nieto-Patlán Douglas B Kuhns Anton Tj Tool Andrés A Arias Matthieu Bouaziz Martin de Boer José Luis Franco Roel P Gazendam John L van Hamme Michel van Houdt Karin van Leeuwen Paul Jh Verkuijlen Timo K van den Berg Juan F Alzate Carlos A Arango-Franco Vritika Batura Andrea R Bernasconi Barbara Boardman Claire Booth Siobhan O Burns Felipe Cabarcas Nadine Cerf Bensussan Fabienne Charbit-Henrion Anniek Corveleyn Caroline Deswarte María Esnaola Azcoiti Dirk Foell John I Gallin Carlos Garcés Margarida Guedes Claas H Hinze Steven M Holland Stephen M Hughes Patricio Ibañez Harry L Malech Isabelle Meyts Marcela Moncada-Velez Kunihiko Moriya Esmeralda Neves Matias Oleastro Laura Perez Vimel Rattina Carmen Oleaga-Quintas Neil Warner Aleixo M Muise Jeanet Serafín López Eunice Trindade Julia Vasconcelos Séverine Vermeire Helmut Wittkowski Austen Worth Laurent Abel Mary C Dinauer Peter D Arkwright Dirk Roos Jean-Laurent Casanova Taco W Kuijpers Jacinta Bustamante

J Clin Invest 2018 08 6;128(9):3957-3975. Epub 2018 Aug 6.

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.

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https://www.jci.org/articles/view/97116
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http://dx.doi.org/10.1172/JCI97116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118590PMC
August 2018

Identification of an Amino Acid Motif in HLA-DRβ1 That Distinguishes Uveitis in Patients With Juvenile Idiopathic Arthritis.

Authors:
Anne-Mieke J W Haasnoot Marco W Schilham Sylvia Kamphuis Petra C E Hissink Muller Arnd Heiligenhaus Dirk Foell Kirsten Minden Roel A Ophoff Timothy R D J Radstake Anneke I Den Hollander Tjitske H C M Reinards Sanne Hiddingh Nicoline E Schalij-Delfos Esther P A H Hoppenreijs Marion A J van Rossum Carine Wouters Rotraud K Saurenmann J Merlijn van den Berg Nico M Wulffraat Rebecca Ten Cate Joke H de Boer Sara L Pulit Jonas J W Kuiper

Arthritis Rheumatol 2018 07 29;70(7):1155-1165. Epub 2018 May 29.

University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/art.40484DOI Listing
July 2018

JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies.

Authors:
Gina A Montealegre Sanchez Adam Reinhardt Suzanne Ramsey Helmut Wittkowski Philip J Hashkes Yackov Berkun Susanne Schalm Sara Murias Jason A Dare Diane Brown Deborah L Stone Ling Gao Thomas Klausmeier Dirk Foell Adriana A de Jesus Dawn C Chapelle Hanna Kim Samantha Dill Robert A Colbert Laura Failla Bahar Kost Michelle O'Brien James C Reynolds Les R Folio Katherine R Calvo Scott M Paul Nargues Weir Alessandra Brofferio Ariane Soldatos Angelique Biancotto Edward W Cowen John J Digiovanna Massimo Gadina Andrew J Lipton Colleen Hadigan Steven M Holland Joseph Fontana Ahmad S Alawad Rebecca J Brown Kristina I Rother Theo Heller Kristina M Brooks Parag Kumar Stephen R Brooks Meryl Waldman Harsharan K Singh Volker Nickeleit Maria Silk Apurva Prakash Jonathan M Janes Seza Ozen Paul G Wakim Paul A Brogan William L Macias Raphaela Goldbach-Mansky

J Clin Invest 2018 07 11;128(7):3041-3052. Epub 2018 Jun 11.

Translational Autoinflammatory Disease Section, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1172/JCI98814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026004PMC
July 2018

Proteomics in Chronic Arthritis-Will We Finally Have Useful Biomarkers?

Authors:
Christoph Kessel Angela McArdle Emely Verweyen Toni Weinhage Helmut Wittkowski Stephen R Pennington Dirk Foell

Curr Rheumatol Rep 2018 07 14;20(9):53. Epub 2018 Jul 14.

Department of Paediatric Rheumatology and Immunology, University of Muenster, Domagkstraße 3, 48149, Muenster, Germany.

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http://dx.doi.org/10.1007/s11926-018-0762-0DOI Listing
July 2018

Characterization of drug-neutralizing antibodies in patients with Fabry disease during infusion.

Authors:
Malte Lenders Boris Schmitz Stefan-Martin Brand Dirk Foell Eva Brand

J Allergy Clin Immunol 2018 06 5;141(6):2289-2292.e7. Epub 2018 Feb 5.

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.12.1001DOI Listing
June 2018

Reversal of Sepsis-Like Features of Neutrophils by Interleukin-1 Blockade in Patients With Systemic-Onset Juvenile Idiopathic Arthritis.

Authors:
Nienke M Ter Haar Tamar Tak Michal Mokry Rianne C Scholman Jenny M Meerding Wilco de Jager Anouk Verwoerd Dirk Foell Thomas Vogl Johannes Roth Pieter H C Leliefeld Jorg van Loosdregt Leo Koenderman Sebastiaan J Vastert Sytze de Roock

Arthritis Rheumatol 2018 06 7;70(6):943-956. Epub 2018 May 7.

University Medical Center Utrecht, Wilhelmina Children's Hospital and Utrecht University, Utrecht, The Netherlands.

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http://doi.wiley.com/10.1002/art.40442
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http://dx.doi.org/10.1002/art.40442DOI Listing
June 2018

Treating juvenile idiopathic arthritis to target: recommendations of an international task force.

Authors:
Angelo Ravelli Alessandro Consolaro Gerd Horneff Ronald M Laxer Daniel J Lovell Nico M Wulffraat Jonathan D Akikusa Sulaiman M Al-Mayouf Jordi Antón Tadej Avcin Roberta A Berard Michael W Beresford Ruben Burgos-Vargas Rolando Cimaz Fabrizio De Benedetti Erkan Demirkaya Dirk Foell Yasuhiko Itoh Pekka Lahdenne Esi M Morgan Pierre Quartier Nicolino Ruperto Ricardo Russo Claudia Saad-Magalhães Sujata Sawhney Christiaan Scott Susan Shenoi Joost F Swart Yosef Uziel Sebastiaan J Vastert Josef S Smolen

Ann Rheum Dis 2018 06 11;77(6):819-828. Epub 2018 Apr 11.

Division of Rheumatology, Department of Medicine3, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1136/annrheumdis-2018-213030DOI Listing
June 2018

Development of practice and consensus-based strategies including a treat-to-target approach for the management of moderate and severe juvenile dermatomyositis in Germany and Austria.

Authors:
Claas H Hinze Prasad T Oommen Frank Dressler Andreas Urban Frank Weller-Heinemann Fabian Speth Elke Lainka Jürgen Brunner Heike Fesq Dirk Foell Wolfgang Müller-Felber Ulrich Neudorf Christoph Rietschel Tobias Schwarz Ulrike Schara Johannes-Peter Haas

Pediatr Rheumatol Online J 2018 Jun 25;16(1):40. Epub 2018 Jun 25.

German Center for Pediatric and Adolescent Rheumatology, Garmisch-Partenkirchen Department of Dermatology, Oberammergau Center for Rheumatic Diseases, Oberammergau, Germany.

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http://dx.doi.org/10.1186/s12969-018-0257-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019723PMC
June 2018

Peripheral blood monocytes reveal an activated phenotype in pediatric uveitis.

Authors:
Karoline Walscheid Lisa Neekamp Arnd Heiligenhaus Toni Weinhage Dirk Holzinger Carsten Heinz Maren Kasper Dirk Foell

Clin Immunol 2018 05 18;190:84-88. Epub 2017 Sep 18.

Department of Pediatric Rheumatology and Immunology, University Hospital Muenster, Germany.

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http://dx.doi.org/10.1016/j.clim.2017.09.014DOI Listing
May 2018

Increased Circulating Proinflammatory T Lymphocytes in Children with Different Forms of Anterior Uveitis: Results from a Pilot Study.

Authors:
Karoline Walscheid Lisa Neekamp Arnd Heiligenhaus Toni Weinhage Carsten Heinz Dirk Foell

Ocul Immunol Inflamm 2019 17;27(5):788-797. Epub 2018 May 17.

b Department of Pediatric Rheumatology and Immunology, University Hospital Muenster , Muenster , Germany.

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https://www.tandfonline.com/doi/full/10.1080/09273948.2018.1
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May 2018

The majority of patients with newly diagnosed juvenile idiopathic arthritis achieve a health-related quality of life that is similar to that of healthy peers: results of the German multicenter inception cohort (ICON).

Authors:
Miriam Listing Kirsten Mönkemöller Ina Liedmann Martina Niewerth Claudia Sengler Joachim Listing Dirk Foell Arnd Heiligenhaus Ariane Klein Gerd Horneff Gerd Ganser Johannes-Peter Haas Jens Klotsche Kirsten Minden

Arthritis Res Ther 2018 05 30;20(1):106. Epub 2018 May 30.

Deutsches Rheuma-Forschungszentrum Berlin, Epidemiology Unit, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1186/s13075-018-1588-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977761PMC
May 2018

S100A12 Is Associated with Response to Therapy in Juvenile Idiopathic Arthritis.

Authors:
Faekah Gohar Janneke Anink Halima Moncrieffe Lisette W A Van Suijlekom-Smit Femke H M Prince Marion A J van Rossum Koert M Dolman Esther P A H Hoppenreijs Rebecca Ten Cate Simona Ursu Lucy R Wedderburn Gerd Horneff Michael Frosch Dirk Foell Dirk Holzinger

J Rheumatol 2018 04 15;45(4):547-554. Epub 2018 Jan 15.

From the Department of Pediatric Rheumatology and Immunology, University Children's Hospital Münster, Münster, Germany; Department of Pediatrics/Pediatric Rheumatology, Erasmus MC Sophia Children's Hospital Rotterdam, Rotterdam, the Netherlands; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center; Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA; Emma Children's Hospital, Academic Medical Centre and Amsterdam Rheumatology and Immunology Centre, Reade location, Jan van Breemen Institute; Department of Pediatrics/Pediatric Rheumatology, Onze Lieve Vrouwe Gasthuis, Amsterdam; Department of Pediatrics/Pediatric Rheumatology, St. Maartenskliniek and Radboud University Medical Centre, Nijmegen; Leiden University Medical Centre, Leiden, the Netherlands; School of Biological Sciences, Royal Holloway, University of London; Infection, Immunity, Inflammation Programme, University College London (UCL) Great Ormond Street (GOS) Institute of Child Health; UK National Institute for Health Research (NIHR) GOS Hospital Biomedical Research Centre (BRC); Arthritis Research UK Centre for Adolescent Rheumatology at UCL, London, UK; Centre of Pediatric Rheumatology, Department of General Pediatrics, Asklepios Clinic Sankt Augustin, Sankt Augustin; German Pediatric Pain Centre, Children's and Adolescents' Hospital, Datteln; Klinik für Kinderheilkunde III, Zentrum für Kinder- und Jugendmedizin, Universitätsklinikum Essen, Essen, Germany.

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http://dx.doi.org/10.3899/jrheum.170438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880729PMC
April 2018

Anti-inflammatory monocytes-interplay of innate and adaptive immunity.

Authors:
Georg Varga Dirk Foell

Mol Cell Pediatr 2018 Apr 3;5(1). Epub 2018 Apr 3.

Department of Pediatric Rheumatology and Immunology, University Hospital Muenster, University of Muenster, Domagkstr. 3, 48149, Münster, Germany.

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http://dx.doi.org/10.1186/s40348-018-0083-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882470PMC
April 2018

IL-6 blockade in systemic juvenile idiopathic arthritis - achievement of inactive disease and remission (data from the German AID-registry).

Authors:
M Bielak E Husmann N Weyandt J-P Haas B Hügle G Horneff U Neudorf T Lutz E Lilienthal T Kallinich K Tenbrock R Berendes T Niehues H Wittkowski E Weißbarth-Riedel G Heubner P Oommen J Klotsche Dirk Foell E Lainka

Pediatr Rheumatol Online J 2018 Apr 5;16(1):22. Epub 2018 Apr 5.

Department of Pediatric Rheumatology, University Children's Hospital Essen, Hufelandstr. 55, 45147, Essen, Germany.

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https://ped-rheum.biomedcentral.com/articles/10.1186/s12969-
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http://dx.doi.org/10.1186/s12969-018-0236-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887199PMC
April 2018

The German version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR).

Authors:
Dirk Holzinger Dirk Foell Gerd Horneff Ivan Foeldvari Nikolay Tzaribachev Catrin Tzaribachev Kirsten Minden Tilmann Kallinich Gerd Ganser Lucia Clara Johannes-Peter Haas Boris Hügle Hans-Iko Huppertz Frank Weller Alessandro Consolaro Francesca Bovis Nicolino Ruperto

Rheumatol Int 2018 Apr 7;38(Suppl 1):211-218. Epub 2018 Apr 7.

Clinica Pediatrica e Reumatologia, Paediatric Rheumatology International Trials Organisation (PRINTO), Istituto Giannina Gaslini, Via Gaslini 5, 16147, Genoa, Italy.

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http://dx.doi.org/10.1007/s00296-018-3953-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893737PMC
April 2018

Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome.

Authors:
Eric S Weiss Charlotte Girard-Guyonvarc'h Dirk Holzinger Adriana A de Jesus Zeshan Tariq Jennifer Picarsic Eduardo J Schiffrin Dirk Foell Alexei A Grom Sandra Ammann Stephan Ehl Tomoaki Hoshino Raphaela Goldbach-Mansky Cem Gabay Scott W Canna

Blood 2018 03 11;131(13):1442-1455. Epub 2018 Jan 11.

RK Mellon Institute, Children's Hospital of Pittsburgh of UPMC/University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1182/blood-2017-12-820852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877443PMC
March 2018

Practice and consensus-based strategies in diagnosing and managing systemic juvenile idiopathic arthritis in Germany.

Authors:
Claas H Hinze Dirk Holzinger Elke Lainka Johannes-Peter Haas Fabian Speth Tilmann Kallinich Nikolaus Rieber Markus Hufnagel Annette F Jansson Christian Hedrich Hanna Winowski Thomas Berger Ivan Foeldvari Gerd Ganser Anton Hospach Hans-Iko Huppertz Kirsten Mönkemöller Ulrich Neudorf Elisabeth Weißbarth-Riedel Helmut Wittkowski Gerd Horneff Dirk Foell

Pediatr Rheumatol Online J 2018 Jan 22;16(1). Epub 2018 Jan 22.

Department of Pediatric Rheumatology and Immunology, University Hospital Münster, Münster, Albert-Schweitzer-Campus 1, Building W30, 48149, Münster, Germany.

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http://dx.doi.org/10.1186/s12969-018-0224-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778670PMC
January 2018

Effect of Adalimumab on Peripheral Blood Mononuclear Cells in Non-Infectious Uveitis.

Authors:
Karoline Walscheid Toni Weinhage Dirk Foell Carsten Heinz Maren Kasper Arnd Heiligenhaus

Ocul Immunol Inflamm 2019 11;27(2):330-337. Epub 2017 Oct 11.

a Department of Ophthalmology and Ophtha Lab at St. Franziskus-Hospital Münster , Münster , Germany.

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http://dx.doi.org/10.1080/09273948.2017.1374415DOI Listing
October 2017

Familial Mediterranean fever in children and adolescents: factors for colchicine dosage and predicting parameters for dose increase.

Authors:
Anne-Marie Knieper Jens Klotsche Elke Lainka Thomas Berger Frank Dressler Annette F Jansson Christoph Rietschel Prasad T Oommen Rainer Berendes Tim Niehues Ulrich Neudorf Dirk Foell Helmut Wittkowski Tilmann Kallinich

Rheumatology (Oxford) 2017 09;56(9):1597-1606

Pediatric Pneumology and Immunology, Charité University Medicine Berlin.

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http://dx.doi.org/10.1093/rheumatology/kex222DOI Listing
September 2017

Alarmins firing arthritis: Helpful diagnostic tools and promising therapeutic targets.

Authors:
Miha Lavric María Auxiliadora Miranda-García Dirk Holzinger Dirk Foell Helmut Wittkowski

Joint Bone Spine 2017 Jul 19;84(4):401-410. Epub 2016 Sep 19.

Department of Paediatric Rheumatology and Immunology, University Children's Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1016/j.jbspin.2016.06.010DOI Listing
July 2017

Proinflammatory Cytokine Environments Can Drive Interleukin-17 Overexpression by γ/δ T Cells in Systemic Juvenile Idiopathic Arthritis.

Authors:
Christoph Kessel Katrin Lippitz Toni Weinhage Claas Hinze Helmut Wittkowski Dirk Holzinger Ndate Fall Alexei A Grom Niklas Gruen Dirk Foell

Arthritis Rheumatol 2017 07 12;69(7):1480-1494. Epub 2017 Jun 12.

University Children's Hospital, Münster, Germany.

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http://dx.doi.org/10.1002/art.40099DOI Listing
July 2017

Early Outcomes in Children With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Authors:
Kimberly A Morishita Lakshmi N Moorthy Joanna M Lubieniecka Marinka Twilt Rae S M Yeung Mary B Toth Susan Shenoi Goran Ristic Susan M Nielsen Raashid A Luqmani Suzanne C Li Tzielan Lee Erica F Lawson Mikhail M Kostik Marisa Klein-Gitelman Adam M Huber Aimee O Hersh Dirk Foell Melissa E Elder Barbara A Eberhard Paul Dancey Sirirat Charuvanij Susanne M Benseler David A Cabral

Arthritis Rheumatol 2017 07 9;69(7):1470-1479. Epub 2017 Jun 9.

Kimberly A. Morishita, MD, MHSc, David A. Cabral, MBBS: British Columbia Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/art.40112DOI Listing
July 2017

Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications.

Authors:
Michael J Ombrello Victoria L Arthur Elaine F Remmers Anne Hinks Ioanna Tachmazidou Alexei A Grom Dirk Foell Alberto Martini Marco Gattorno Seza Özen Sampath Prahalad Andrew S Zeft John F Bohnsack Norman T Ilowite Elizabeth D Mellins Ricardo Russo Claudio Len Maria Odete E Hilario Sheila Oliveira Rae S M Yeung Alan M Rosenberg Lucy R Wedderburn Jordi Anton Johannes-Peter Haas Angela Rosen-Wolff Kirsten Minden Klaus Tenbrock Erkan Demirkaya Joanna Cobb Elizabeth Baskin Sara Signa Emily Shuldiner Richard H Duerr Jean-Paul Achkar M Ilyas Kamboh Kenneth M Kaufman Leah C Kottyan Dalila Pinto Stephen W Scherer Marta E Alarcón-Riquelme Elisa Docampo Xavier Estivill Ahmet Gül Carl D Langefeld Susan Thompson Eleftheria Zeggini Daniel L Kastner Patricia Woo Wendy Thomson

Ann Rheum Dis 2017 May 7;76(5):906-913. Epub 2016 Dec 7.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2016-210324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530341PMC
May 2017

Munchausen by proxy syndrome mimicking systemic autoinflammatory disease: case report and review of the literature.

Authors:
Helmut Wittkowski Claas Hinze Sigrid Häfner-Harms Vinzenz Oji Katja Masjosthusmann Martina Monninger Ulrike Grenzebach Dirk Foell

Pediatr Rheumatol Online J 2017 Apr 5;15(1):19. Epub 2017 Apr 5.

Department of Paediatric Rheumatology and Immunology, University Children's Hospital Muenster, Albert-Schweitzer-Campus 1, Bld. W30, D-48149, Muenster, Germany.

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http://dx.doi.org/10.1186/s12969-017-0152-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382472PMC
April 2017

Autoinflammatory diseases: New diagnostic criteria for CAPS - turning horses into zebras?

Authors:
Claas Hinze Dirk Foell

Nat Rev Rheumatol 2017 01 8;13(1):7-8. Epub 2016 Dec 8.

Department of Pediatric Rheumatology and Immunology, University Hospital Münster, Albert-Schweitzer-Campus 1, Münster D-48149, Germany.

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http://www.nature.com/articles/nrrheum.2016.201
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http://dx.doi.org/10.1038/nrrheum.2016.201DOI Listing
January 2017

Correlation of Secretory Activity of Neutrophils With Genotype in Patients With Familial Mediterranean Fever.

Authors:
Faekah Gohar Banu Orak Tilmann Kallinich Marion Jeske Mareike Lieber Horst von Bernuth Arnd Giese Elisabeth Weissbarth-Riedel Johannes-Peter Haas Frank Dressler Dirk Holzinger Peter Lohse Ulrich Neudorf Elke Lainka Claas Hinze Katja Masjosthusmann Christoph Kessel Toni Weinhage Dirk Foell Helmut Wittkowski

Arthritis Rheumatol 2016 12;68(12):3010-3022

University Children's Hospital, Muenster, Germany.

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http://dx.doi.org/10.1002/art.39784DOI Listing
December 2016

S100A8/A9, a potent serum and molecular imaging biomarker for synovial inflammation and joint destruction in seronegative experimental arthritis.

Authors:
Edwin J W Geven Martijn H J van den Bosch Irene Di Ceglie Giuliana Ascone Shahla Abdollahi-Roodsaz Annet W Sloetjes Sven Hermann Michael Schäfers Fons A J van de Loo Peter M van der Kraan Marije I Koenders Dirk Foell Johannes Roth Thomas Vogl Peter L E M van Lent

Arthritis Res Ther 2016 10 24;18(1):247. Epub 2016 Oct 24.

Experimental Rheumatology, Radboud University Medical Center, PO Box 9101, 6525, GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s13075-016-1121-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078998PMC
October 2016

Phenotypic changes of peripheral blood mononuclear cells upon corticosteroid treatment in idiopathic intermediate uveitis.

Authors:
Karoline Walscheid Toni Weinhage Dirk Foell Carsten Heinz Maren Kasper Arnd Heiligenhaus

Clin Immunol 2016 Oct 28. Epub 2016 Oct 28.

Department of Ophthalmology, Ophtha Lab at St. Franziskus-Hospital, Muenster, Germany; Department of Ophthalmology, University of Duisburg-, Essen, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S15216616163053
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http://dx.doi.org/10.1016/j.clim.2016.10.013DOI Listing
October 2016

Activation-dependent cell death of human monocytes is a novel mechanism of fine-tuning inflammation and autoimmunity.

Authors:
Jan Däbritz Toni Weinhage Georg Varga Timo Wirth Jan M Ehrchen Katarzyna Barczyk-Kahlert Johannes Roth Tobias Schwarz Dirk Foell

Eur J Immunol 2016 08 27;46(8):1997-2007. Epub 2016 May 27.

Department of Pediatric Rheumatology and Immunology, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1002/eji.201545802DOI Listing
August 2016

Review of biomarkers in systemic juvenile idiopathic arthritis: helpful tools or just playing tricks?

Authors:
Faekah Gohar Christoph Kessel Miha Lavric Dirk Holzinger Dirk Foell

Arthritis Res Ther 2016 07 13;18:163. Epub 2016 Jul 13.

Department of Paediatric Rheumatology and Immunology, University of Münster, Domagkstraße 3, D-48149, Münster, Germany.

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http://dx.doi.org/10.1186/s13075-016-1069-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944486PMC
July 2016

Sleep Fragmentation and Biomarkers in Juvenile Idiopathic Arthritis.

Authors:
Teresa M Ward Weichao Yuwen Joachim Voss Dirk Foell Faekah Gohar Sarah Ringold

Biol Res Nurs 2016 May 27;18(3):299-306. Epub 2015 Oct 27.

Department of Pediatrics, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, WA, USA.

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http://journals.sagepub.com/doi/ 10.1177/1099800415609997
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http://dx.doi.org/10.1177/1099800415609997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942487PMC
May 2016

Detection of Early Murine Colorectal Cancer by MMP-2/-9-Guided Fluorescence Endoscopy.

Authors:
Katrin Schwegmann Dominik Bettenworth Sven Hermann Andreas Faust Christopher Poremba Dirk Foell Michael Schäfers Dirk Domagk Philipp Lenz

Inflamm Bowel Dis 2016 Jan;22(1):82-91

*European Institute for Molecular Imaging, University of Münster, Münster, Germany; †Department of Medicine B, University Hospital Münster, Germany; ‡Institute of Pathology Munich-North, Munich, Germany; §Department of Pediatric Rheumatology and Immunology, University Children's Hospital Münster, Germany; and ‖Cells-in-Motion Cluster of Excellence (EXC 1003-CiM), University of Münster, Münster, Germany.

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https://academic.oup.com/ibdjournal/article/22/1/82-91/45618
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http://dx.doi.org/10.1097/MIB.0000000000000605DOI Listing
January 2016

Increased serum concentrations of neutrophil-derived protein S100A12 in heterozygous carriers of MEFV mutations.

Authors:
Mareike Lieber Tilmann Kallinich Peter Lohse Jens Klotsche Dirk Holzinger Dirk Foell Helmut Wittkowski

Clin Exp Rheumatol 2015 Nov-Dec;33(6 Suppl 94):S113-6. Epub 2015 Oct 19.

Department of Paediatric Rheumatology and Immunology, University Children's Hospital Münster, Germany.

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January 2016

HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.

Authors:
Michael J Ombrello Elaine F Remmers Ioanna Tachmazidou Alexei Grom Dirk Foell Johannes-Peter Haas Alberto Martini Marco Gattorno Seza Özen Sampath Prahalad Andrew S Zeft John F Bohnsack Elizabeth D Mellins Norman T Ilowite Ricardo Russo Claudio Len Maria Odete E Hilario Sheila Oliveira Rae S M Yeung Alan Rosenberg Lucy R Wedderburn Jordi Anton Tobias Schwarz Anne Hinks Yelda Bilginer Jane Park Joanna Cobb Colleen L Satorius Buhm Han Elizabeth Baskin Sara Signa Richard H Duerr J P Achkar M Ilyas Kamboh Kenneth M Kaufman Leah C Kottyan Dalila Pinto Stephen W Scherer Marta E Alarcón-Riquelme Elisa Docampo Xavier Estivill Ahmet Gül Paul I W de Bakker Soumya Raychaudhuri Carl D Langefeld Susan Thompson Eleftheria Zeggini Wendy Thomson Daniel L Kastner Patricia Woo

Proc Natl Acad Sci U S A 2015 Dec 23;112(52):15970-5. Epub 2015 Nov 23.

Center of Paediatric and Adolescent Rheumatology, University College London, London, WC1N 1EH, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1520779112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702958PMC
December 2015

Elevated S100A8/A9 and S100A12 Serum Levels Reflect Intraocular Inflammation in Juvenile Idiopathic Arthritis-Associated Uveitis: Results From a Pilot Study.

Authors:
Karoline Walscheid Arnd Heiligenhaus Dirk Holzinger Johannes Roth Carsten Heinz Christoph Tappeiner Maren Kasper Dirk Foell

Invest Ophthalmol Vis Sci 2015 Dec;56(13):7653-60

Department of Pediatric Rheumatology and Immunology, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1167/iovs.15-17066DOI Listing
December 2015

No association of IL-12p40 pro1.1 polymorphism with juvenile idiopathic arthritis.

Authors:
Christiane S Eberhardt Johannes-Peter Haas Hermann Girschick Tobias Schwarz Henner Morbach Angela Rösen-Wolff Dirk Foell Guenther Dannecker Carsten Schepp Gerd Ganser Nora Honke Thomas Eggermann Jan Müller-Berghaus Norbert Wagner Kim Ohl Klaus Tenbrock

Pediatr Rheumatol Online J 2015 Dec 15;13:61. Epub 2015 Dec 15.

Department of Pediatrics, Division of Pediatric Pneumology, Allergology and Immunology, RWTH Aachen, University, Pauwelsstr 30, D-52074, Aachen, Germany.

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http://www.ped-rheum.com/content/13/1/61
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678695PMC
December 2015

Clinical features of childhood granulomatosis with polyangiitis (wegener's granulomatosis).

Authors:
Marek Bohm Maria Isabel Gonzalez Fernandez Seza Ozen Angela Pistorio Pavla Dolezalova Paul Brogan Giancarlo Barbano Claudia Sengler Marisa Klein-Gitelman Pierre Quartier Anders Fasth Troels Herlin Maria Teresa R A Terreri Susan Nielsen Marion A J van Rossum Tadej Avcin Esteban Rodolfo Castell Ivan Foeldvari Dirk Foell Anuela Kondi Isabelle Koné-Paut Rolf-Michael Kuester Hartmut Michels Nico Wulffraat Halima Ben Amer Clara Malattia Alberto Martini Nicolino Ruperto

Pediatr Rheumatol Online J 2014 26;12:18. Epub 2014 May 26.

Istituto Giannina Gaslini Pediatria II - Reumatologia, PRINTO, Genova, Italy.

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http://dx.doi.org/10.1186/1546-0096-12-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041043PMC
November 2015

Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated inflammatory diseases.

Authors:
Dirk Holzinger Selina Kathleen Fassl Wilco de Jager Peter Lohse Ute F Röhrig Marco Gattorno Alessia Omenetti Sabrina Chiesa Francesca Schena Judith Austermann Thomas Vogl Douglas B Kuhns Steven M Holland Carlos Rodríguez-Gallego Ricardo López-Almaraz Juan I Arostegui Elena Colino Rosa Roldan Smaragdi Fessatou Bertrand Isidor Sylvaine Poignant Koichi Ito Hans-Joerg Epple Jonathan A Bernstein Michael Jeng Jennifer Frankovich Geraldina Lionetti Joseph A Church Peck Y Ong Mona LaPlant Mario Abinun Rod Skinner Venetia Bigley Ulrich J Sachs Claas Hinze Esther Hoppenreijs Jan Ehrchen Dirk Foell Jae Jin Chae Amanda Ombrello Ivona Aksentijevich Cord Sunderkoetter Johannes Roth

J Allergy Clin Immunol 2015 Nov 27;136(5):1337-45. Epub 2015 May 27.

Institute of Immunology, University of Muenster, Muenster, Germany; Interdisciplinary Centre for Clinical Research IZKF, University Hospital Muenster, University of Muenster, Muenster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591125PMC
November 2015

Redox distress and genetic defects conspire in systemic autoinflammatory diseases.

Authors:
Georg Varga Marco Gattorno Dirk Foell Anna Rubartelli

Nat Rev Rheumatol 2015 Nov 4;11(11):670-80. Epub 2015 Aug 4.

Cell Biology Unit, IRCCS Azienda Ospedaliera Universitaria San Martino-IST, Largo Rosanna Benzi 10, 16132 Genoa, Italy.

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http://dx.doi.org/10.1038/nrrheum.2015.105DOI Listing
November 2015

MRP8/14 serum levels as a predictor of response to starting and stopping anti-TNF treatment in juvenile idiopathic arthritis.

Authors:
Janneke Anink Lisette W A Van Suijlekom-Smit Marieke H Otten Femke H M Prince Marion A J van Rossum Koert M Dolman Esther P A H Hoppenreijs Rebecca ten Cate Simona Ursu Lucy R Wedderburn Gerd Horneff Michael Frosch Thomas Vogl Faekah Gohar Dirk Foell Johannes Roth Dirk Holzinger

Arthritis Res Ther 2015 Aug 7;17:200. Epub 2015 Aug 7.

Interdisciplinary Centre for Clinical Research IZKF, University Hospital Muenster, Muenster and Department of Pediatric Rheumatology and Immunology, University Children's Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1186/s13075-015-0723-1DOI Listing
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August 2015

Granulocyte Macrophage Colony-Stimulating Factor-Activated CD39/CD73 Murine Monocytes Modulate Intestinal Inflammation via Induction of Regulatory T Cells.

Authors:
Toni Weinhage Jan Däbritz Anne Brockhausen Timo Wirth Markus Brückner Michael Belz Dirk Foell Georg Varga

Cell Mol Gastroenterol Hepatol 2015 Jul 6;1(4):433-449.e1. Epub 2015 May 6.

Department of Pediatric Rheumatology and Immunology, University Children's Hospital Münster, Münster, Germany.

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July 2015

Management of juvenile idiopathic arthritis: hitting the target.

Authors:
Claas Hinze Faekah Gohar Dirk Foell

Nat Rev Rheumatol 2015 May 6;11(5):290-300. Epub 2015 Jan 6.

Department of Paediatric Rheumatology and Immunology, University Children's Hospital Münster, Albert-Schweitzer-Campus 1, Building W30, D-48149 Münster, Germany.

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May 2015

MRP8/14 serum levels as a strong predictor of response to biological treatments in patients with rheumatoid arthritis.

Authors:
Ivy Y Choi Danielle M Gerlag Marieke J Herenius Rogier M Thurlings Carla A Wijbrandts Dirk Foell Thomas Vogl Johannes Roth Paul P Tak Dirk Holzinger

Ann Rheum Dis 2015 Mar 2;74(3):499-505. Epub 2013 Dec 2.

Department of Paediatric Rheumatology and Immunology, University Children's Hospital Muenster, Muenster, Germany Institute of Immunology, University Hospital Muenster, Muenster, Germany.

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March 2015

Reprogramming of monocytes by GM-CSF contributes to regulatory immune functions during intestinal inflammation.

Authors:
Jan Däbritz Toni Weinhage Georg Varga Timo Wirth Karoline Walscheid Anne Brockhausen David Schwarzmaier Markus Brückner Matthias Ross Dominik Bettenworth Johannes Roth Jan M Ehrchen Dirk Foell

J Immunol 2015 Mar 4;194(5):2424-38. Epub 2015 Feb 4.

Department of Pediatric Rheumatology and Immunology, University Children's Hospital Münster, Münster 48149, Germany; Interdisciplinary Center of Clinical Research, University Hospital Münster, Münster 48149, Germany;

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March 2015

Interleukin-22: biomarker of maternal and fetal inflammation?

Authors:
Iliana Bersani Maria Pia De Carolis Dirk Foell Toni Weinhage Esther Diana Rossi Sara De Carolis Serena Antonia Rubortone Costantino Romagnoli Christian Paul Speer

Immunol Res 2015 Feb;61(1-2):4-10

Department of Medical and Surgical Neonatology, Bambino Gesù Children's Hospital, Rome, Italy.

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February 2015

Treatment of Muckle-Wells syndrome: analysis of two IL-1-blocking regimens.

Authors:
Jasmin B Kuemmerle-Deschner Helmut Wittkowski Pascal N Tyrrell Ina Koetter Peter Lohse Katharina Ummenhofer Fabian Reess Sandra Hansmann Assen Koitschev Christoph Deuter Anja Bialkowski Dirk Foell Susanne M Benseler

Arthritis Res Ther 2013 ;15(3):R64

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060562PMC
November 2014

Blood-based candidate biomarkers of the presence of neuropsychiatric systemic lupus erythematosus in children.

Authors:
Hermine I Brunner Marisa S Klein-Gitelman Frank Zelko Dean W Beebe Dirk Foell Jiha Lee Ahmad Zaal Jordan Jones Tresa Roebuck-Spencer Jun Ying

Lupus Sci Med 2014 5;1(1):e000038. Epub 2014 Nov 5.

Department of Environmental Health , University of Cincinnati College of Medicine , Cincinnati, Ohio , USA.

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November 2014

Monocyte-induced development of Th17 cells and the release of S100 proteins are involved in the pathogenesis of graft-versus-host disease.

Authors:
Katharina Reinhardt Dirk Foell Thomas Vogl Markus Mezger Helmut Wittkowski Falko Fend Birgit Federmann Christian Gille Tobias Feuchtinger Peter Lang Rupert Handgretinger Wolfgang Andreas Bethge Ursula Holzer

J Immunol 2014 Oct 3;193(7):3355-65. Epub 2014 Sep 3.

University Children's Hospital, 72076 Tuebingen, Germany;

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October 2014

Murine endoscopy for in vivo multimodal imaging of carcinogenesis and assessment of intestinal wound healing and inflammation.

Authors:
Markus Brückner Philipp Lenz Tobias M Nowacki Friederike Pott Dirk Foell Dominik Bettenworth

J Vis Exp 2014 Aug 26(90). Epub 2014 Aug 26.

Department of Medicine B, University Hospital Münster;

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August 2014

Validation of relapse risk biomarkers for routine use in patients with juvenile idiopathic arthritis.

Authors:
Friederike Rothmund Joachim Gerss Nicolino Ruperto Jan Däbritz Helmut Wittkowski Michael Frosch Nico M Wulffraat Lucy R Wedderburn Dirk Holzinger Faekah Gohar Sebastiaan J Vastert Riva Brik Chantel Job Deslandre Jose Antonio Melo-Gomes Claudia Saad Magalhaes Roberto Barcellona Ricardo Russo Marco Gattorno Alberto Martini Johannes Roth Dirk Foell

Arthritis Care Res (Hoboken) 2014 Jun;66(6):949-55

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June 2014

Myeloid-related proteins 8 and 14 contribute to monosodium urate monohydrate crystal-induced inflammation in gout.

Authors:
Dirk Holzinger Nadine Nippe Thomas Vogl Kristina Marketon Vijayashree Mysore Toni Weinhage Nicola Dalbeth Bregina Pool Tony Merriman Dominique Baeten Annette Ives Nathalie Busso Dirk Foell Sylvette Bas Cem Gabay Johannes Roth

Arthritis Rheumatol 2014 May;66(5):1327-39

University Hospital Muenster and University Children's Hospital Muenster, Muenster, Germany.

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May 2014

Significance of hydrogen breath tests in children with suspected carbohydrate malabsorption.

Authors:
Jan Däbritz Michael Mühlbauer Dirk Domagk Nicole Voos Geraldine Henneböhl Maria L Siemer Dirk Foell

BMC Pediatr 2014 Feb 27;14:59. Epub 2014 Feb 27.

Department of Pediatric Rheumatology and Immunology, University Children's Hospital Münster, Röntgenstr 21, Münster 48149, NRW, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975941PMC
February 2014

Diagnostic utility of faecal biomarkers in patients with irritable bowel syndrome.

Authors:
Jan Däbritz Jason Musci Dirk Foell

World J Gastroenterol 2014 Jan;20(2):363-75

Jan Däbritz, Gastrointestinal Research in Inflammation and Pathology, Murdoch Children's Research Institute, The Royal Children's Hospital Melbourne, Parkville 3052, VIC, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923012PMC
January 2014

Peripheral monocyte functions and activation in patients with quiescent Crohn's disease.

Authors:
David Schwarzmaier Dirk Foell Toni Weinhage Georg Varga Jan Däbritz

PLoS One 2013 26;8(4):e62761. Epub 2013 Apr 26.

Department of Pediatric Rheumatology and Immunology, University Children's Hospital Münster, Münster, NRW, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637246PMC
December 2013

Granulocyte macrophage colony-stimulating factor auto-antibodies and disease relapse in inflammatory bowel disease.

Authors:
Jan Däbritz Erin Bonkowski Claudia Chalk Bruce C Trapnell Jost Langhorst Lee A Denson Dirk Foell

Am J Gastroenterol 2013 Dec 22;108(12):1901-10. Epub 2013 Oct 22.

1] Department of Pediatric Rheumatology and Immunology, University Children's Hospital Münster, Münster, Germany [2] Interdisciplinary Center of Clinical Research, University of Münster, Münster, Germany [3] The Royal Children's Hospital Melbourne, Murdoch Children's Research Institute, Parkville, Victoria, Australia [4] Department of Pediatrics, University of Melbourne, Melboure Medical School, Parkville, Victoria, Australia.

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December 2013

Increased intracellular oxygen radical production in neutrophils during febrile episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome.

Authors:
Martina Sundqvist Per Wekell Veronica Osla Johan Bylund Karin Christenson Karin Sävman Dirk Foell David A Cabral Anders Fasth Stefan Berg Kelly L Brown Anna Karlsson

Arthritis Rheum 2013 Nov;65(11):2971-83

University of Gothenburg, Gothenburg, Sweden.

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November 2013

Long-term safety and efficacy of rilonacept in patients with systemic juvenile idiopathic arthritis.

Authors:
Daniel J Lovell Edward H Giannini Andreas O Reiff Yukiko Kimura Suzanne Li Philip J Hashkes Carol A Wallace Karen B Onel Dirk Foell Richard Wu Stephanie Biedermann Jennifer D Hamilton Allen R Radin

Arthritis Rheum 2013 Sep;65(9):2486-96

Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio.

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September 2013

Fecal S100A12: identifying intestinal distress in very-low-birth-weight infants.

Authors:
Jan Däbritz Dirk Foell Stefan Wirth Andreas Jenke

J Pediatr Gastroenterol Nutr 2013 Aug;57(2):204-10

Royal Children's Hospital Melbourne, Murdoch Children's Research Institute, Parkville, Australia.

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August 2013

Phagocyte-derived S100 proteins in autoinflammation: putative role in pathogenesis and usefulness as biomarkers.

Authors:
Christoph Kessel Dirk Holzinger Dirk Foell

Clin Immunol 2013 Jun 7;147(3):229-41. Epub 2012 Dec 7.

Department of Pediatric Rheumatology and Immunology, University Children's Hospital, University of Muenster, Germany.

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June 2013

Proinflammatory S100A12 can activate human monocytes via Toll-like receptor 4.

Authors:
Dirk Foell Helmut Wittkowski Christoph Kessel Aloys Lüken Toni Weinhage Georg Varga Thomas Vogl Timo Wirth Dorothee Viemann Per Björk Marieke A D van Zoelen Faekah Gohar Geetha Srikrishna Matthias Kraft Johannes Roth

Am J Respir Crit Care Med 2013 Jun;187(12):1324-34

Department of Pediatric Rheumatology and Immunology, University Children's Hospital Muenster, Muenster, Germany.

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June 2013

Improving relapse prediction in inflammatory bowel disease by neutrophil-derived S100A12.

Authors:
Jan Däbritz Jost Langhorst Andreas Lügering Jan Heidemann Miriam Mohr Helmut Wittkowski Thomas Krummenerl Dirk Foell

Inflamm Bowel Dis 2013 May;19(6):1130-8

Department of Pediatric Rheumatology and Immunology, University Children's Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1097/MIB.0b013e318280b1cdDOI Listing
May 2013

The alarmin Mrp8/14 as regulator of the adaptive immune response during allergic contact dermatitis.

Authors:
Beatrix Petersen Marc Wolf Judith Austermann Peter van Lent Dirk Foell Martina Ahlmann Verena Kupas Karin Loser Clemens Sorg Johannes Roth Thomas Vogl

EMBO J 2013 Jan 27;32(1):100-11. Epub 2012 Nov 27.

Institute of Immunology, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1038/emboj.2012.309DOI Listing
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January 2013

Phagocyte-specific S100 proteins and high-sensitivity C reactive protein as biomarkers for a risk-adapted treatment to maintain remission in juvenile idiopathic arthritis: a comparative study.

Authors:
Joachim Gerss Johannes Roth Dirk Holzinger Nicolino Ruperto Helmut Wittkowski Michael Frosch Nico Wulffraat Lucy Wedderburn Valda Stanevicha Dimitrina Mihaylova Miroslav Harjacek Claudio Len Claudia Toppino Massimo Masi Kirsten Minden Traudel Saurenmann Yosef Uziel Richard Vesely Maria Teresa Apaz Rolf-Michael Kuester Maria Jesus Rua Elorduy Ruben Burgos-Vargas Maka Ioseliani Silvia Magni-Manzoni Erbil Unsal Jordi Anton Zsolt Balogh Stefan Hagelberg Henryka Mazur-Zielinska Tsivia Tauber Alberto Martini Dirk Foell

Ann Rheum Dis 2012 Dec 11;71(12):1991-7. Epub 2012 Jun 11.

Institute of Biostatistics and Clinical Research, University of Muenster, Muenster, Germany.

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December 2012

Fecal phagocyte-specific S100A12 for diagnosing necrotizing enterocolitis.

Authors:
Jan Däbritz Andreas Jenke Stefan Wirth Dirk Foell

J Pediatr 2012 Dec 15;161(6):1059-64. Epub 2012 Jul 15.

Institute of Immunology, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1016/j.jpeds.2012.06.003DOI Listing
December 2012

Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome.

Authors:
Dirk Holzinger Laura Gieldon Vijayashree Mysore Nadine Nippe Debra J Taxman Joseph A Duncan Peter M Broglie Kristina Marketon Judith Austermann Thomas Vogl Dirk Foell Silke Niemann Georg Peters Johannes Roth Bettina Löffler

J Leukoc Biol 2012 Nov 14;92(5):1069-81. Epub 2012 Aug 14.

Institute of Immunology, Department of General Pediatrics, University Children’s Hospital Münster, Münster, Germany.

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November 2012

Multiple juvenile idiopathic arthritis subtypes demonstrate proinflammatory IgG glycosylation.

Authors:
Altan Ercan Michael G Barnes Melissa Hazen Heather Tory Lauren Henderson Fatma Dedeoglu Robert C Fuhlbrigge Alexei Grom Ingrid A Holm Mark Kellogg Susan Kim Barbara Adamczyk Pauline M Rudd Mary Beth Son Robert P Sundel Dirk Foell David N Glass Susan D Thompson Peter A Nigrovic

Arthritis Rheum 2012 Sep;64(9):3025-33

Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429730PMC
September 2012

The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis.

Authors:
Dirk Holzinger Michael Frosch Astrid Kastrup Femke H M Prince Marieke H Otten Lisette W A Van Suijlekom-Smit Rebecca ten Cate Esther P A H Hoppenreijs Sandra Hansmann Halima Moncrieffe Simona Ursu Lucy R Wedderburn Johannes Roth Dirk Foell Helmut Wittkowski

Ann Rheum Dis 2012 Jun 20;71(6):974-80. Epub 2012 Jan 20.

Institute of Immunology, University Hospital Muenster, Muenster, Germany.

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June 2012

CREMα overexpression decreases IL-2 production, induces a T(H)17 phenotype and accelerates autoimmunity.

Authors:
Ralph Lippe Kim Ohl Georg Varga Thomas Rauen Jose C Crispin Yuang-Taung Juang Stefanie Kuerten Frank Tacke Marc Wolf Kirsten Roebrock Thomas Vogl Eva Verjans Nora Honke Jan Ehrchen Dirk Foell Boris Skryabin Norbert Wagner George C Tsokos Johannes Roth Klaus Tenbrock

J Mol Cell Biol 2012 Apr 20;4(2):121-3. Epub 2012 Feb 20.

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April 2012

MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes.

Authors:
Helmut Wittkowski Jasmin B Kuemmerle-Deschner Judith Austermann Dirk Holzinger Raphaela Goldbach-Mansky Katharina Gramlich Peter Lohse Thomas Jung Johannes Roth Susanne M Benseler Dirk Foell

Ann Rheum Dis 2011 Dec 8;70(12):2075-2081. Epub 2011 Sep 8.

Institute of Immunology, University of Muenster, Muenster, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174360PMC
December 2011

Therapeutic approaches in the treatment of juvenile dermatomyositis in patients with recent-onset disease and in those experiencing disease flare: an international multicenter PRINTO study.

Authors:
Rachana Hasija Angela Pistorio Angelo Ravelli Erkan Demirkaya Raju Khubchandani Dinara Guseinova Clara Malattia Helena Canhao Liora Harel Dirk Foell Carine Wouters Carmen De Cunto Christian Huemer Yukiko Kimura Harald Mangge Carlo Minetti Ellen Berit Nordal Pierre Philippet Rosaria Garozzo Alberto Martini Nicolino Ruperto

Arthritis Rheum 2011 Oct;63(10):3142-52

IRCCS G. Gaslini, Genoa, Italy.

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October 2011

The functional -374T/A polymorphism of the receptor for advanced glycation end products may modulate Crohn's disease.

Authors:
Jan Däbritz Frauke Friedrichs Toni Weinhage Jochen Hampe Torsten Kucharzik Andreas Lügering Ulrich Broeckel Stefan Schreiber Tilmann Spieker Monika Stoll Dirk Foell

Am J Physiol Gastrointest Liver Physiol 2011 May 10;300(5):G823-32. Epub 2011 Feb 10.

Dept. of General Pediatrics, Univ. Children's Hospital Muenster, Münster, Germany.

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May 2011

Granulocyte macrophage-colony-stimulating factor autoantibodies and increased intestinal permeability in Crohn disease.

Authors:
Cade M Nylund Sharon D'Mello Mi-Ok Kim Erin Bonkowski Jan Däbritz Dirk Foell Jon Meddings Bruce C Trapnell Lee A Denson

J Pediatr Gastroenterol Nutr 2011 May;52(5):542-8

Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

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May 2011

Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome.

Authors:
Jasmin B Kuemmerle-Deschner Pascal N Tyrrell Ina Koetter Helmut Wittkowski Anja Bialkowski Nicolai Tzaribachev Peter Lohse Assen Koitchev Christoph Deuter Dirk Foell Susanne M Benseler

Arthritis Rheum 2011 Mar;63(3):840-9

University Hospital Tübingen, Tübingen, Germany.

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March 2011

B cell depletion for autoimmune diseases in paediatric patients.

Authors:
Annette F Jansson Claudia Sengler Jasmin Kuemmerle-Deschner Bernd Gruhn A Birgitta Kranz Hartwig Lehmann Daniela Kleinert Lars Pape Hermann J Girschick Ivan Foeldvari Dieter Haffner Johannes P Haas Dagmar Moebius Dirk Foell Joachim Peitz Veit Grote

Clin Rheumatol 2011 Jan 1;30(1):87-97. Epub 2010 Dec 1.

Ludwig-Maximilians University, Munich, Germany.

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January 2011

Translational research network and patient registry for auto-inflammatory diseases.

Authors:
Elke Lainka Maria Bielak Volker Hilger Oliver Basu Ulrich Neudorf Helmut Wittkowski Dirk Holzinger Johannes Roth Tim Niehues Dirk Foell

Rheumatology (Oxford) 2011 Jan;50(1):237-42

Department of Paediatric Rheumatology, Children's Hospital, University Duisburg-Essen, Essen, Germany.

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January 2011