Publications by authors named "Dirk Brenner"

49Publications

Regulatory t cell metabolism at the intersection between autoimmune diseases and cancer.

Eur J Immunol 2020 Oct 16. Epub 2020 Oct 16.

Experimental and Molecular Immunology, Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.

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http://dx.doi.org/10.1002/eji.201948470DOI Listing
October 2020

Metabolic Modulation of Immunity: A New Concept in Cancer Immunotherapy.

Cell Rep 2020 Jul;32(1):107848

Experimental & Molecular Immunology, Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg; Odense Research Center for Anaphylaxis, Department of Dermatology and Allergy Center, Odense University Hospital, University of Southern Denmark, Odense, Denmark; Immunology and Genetics, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Belvaux, Luxembourg. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107848DOI Listing
July 2020

Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function.

Cell Metab 2020 May 25;31(5):920-936.e7. Epub 2020 Mar 25.

Experimental & Molecular Immunology, Department of Infection and Immunity, Luxembourg Institute of Health, 29 Rue Henri Koch, Esch-sur-Alzette, Luxembourg; Odense Research Center for Anaphylaxis (ORCA), Department of Dermatology and Allergy Center, Odense University Hospital, University of Southern Denmark, Odense, Denmark; Immunology & Genetics, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 7 Avenue des Hauts Fourneaux, Esch-sur-Alzette, Luxembourg. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2020.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265172PMC
May 2020

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam-Klages William W Agace Nima Aghaeepour Mübeccel Akdis Matthieu Allez Larissa Nogueira Almeida Giorgia Alvisi Graham Anderson Immanuel Andrä Francesco Annunziato Achille Anselmo Petra Bacher Cosima T Baldari Sudipto Bari Vincenzo Barnaba Joana Barros-Martins Luca Battistini Wolfgang Bauer Sabine Baumgart Nicole Baumgarth Dirk Baumjohann Bianka Baying Mary Bebawy Burkhard Becher Wolfgang Beisker Vladimir Benes Rudi Beyaert Alfonso Blanco Dominic A Boardman Christian Bogdan Jessica G Borger Giovanna Borsellino Philip E Boulais Jolene A Bradford Dirk Brenner Ryan R Brinkman Anna E S Brooks Dirk H Busch Martin Büscher Timothy P Bushnell Federica Calzetti Garth Cameron Ilenia Cammarata Xuetao Cao Susanna L Cardell Stefano Casola Marco A Cassatella Andrea Cavani Antonio Celada Lucienne Chatenoud Pratip K Chattopadhyay Sue Chow Eleni Christakou Luka Čičin-Šain Mario Clerici Federico S Colombo Laura Cook Anne Cooke Andrea M Cooper Alexandra J Corbett Antonio Cosma Lorenzo Cosmi Pierre G Coulie Ana Cumano Ljiljana Cvetkovic Van Duc Dang Chantip Dang-Heine Martin S Davey Derek Davies Sara De Biasi Genny Del Zotto Gelo Victoriano Dela Cruz Michael Delacher Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing James P Di Santo Andreas Diefenbach Francesco Dieli Andreas Dolf Thomas Dörner Regine J Dress Diana Dudziak Michael Dustin Charles-Antoine Dutertre Friederike Ebner Sidonia B G Eckle Matthias Edinger Pascale Eede Götz R A Ehrhardt Marcus Eich Pablo Engel Britta Engelhardt Anna Erdei Charlotte Esser Bart Everts Maximilien Evrard Christine S Falk Todd A Fehniger Mar Felipo-Benavent Helen Ferry Markus Feuerer Andrew Filby Kata Filkor Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Britta Frehse Paul S Frenette Stefan Frischbutter Wolfgang Fritzsche David W Galbraith Anastasia Gangaev Natalio Garbi Brice Gaudilliere Ricardo T Gazzinelli Jens Geginat Wilhelm Gerner Nicholas A Gherardin Kamran Ghoreschi Lara Gibellini Florent Ginhoux Keisuke Goda Dale I Godfrey Christoph Goettlinger Jose M González-Navajas Carl S Goodyear Andrea Gori Jane L Grogan Daryl Grummitt Andreas Grützkau Claudia Haftmann Jonas Hahn Hamida Hammad Günter Hämmerling Leo Hansmann Goran Hansson Christopher M Harpur Susanne Hartmann Andrea Hauser Anja E Hauser David L Haviland David Hedley Daniela C Hernández Guadalupe Herrera Martin Herrmann Christoph Hess Thomas Höfer Petra Hoffmann Kristin Hogquist Tristan Holland Thomas Höllt Rikard Holmdahl Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Fang-Ping Huang Johanna E Huber Jochen Huehn Michael Hundemer Christopher A Hunter William Y K Hwang Anna Iannone Florian Ingelfinger Sabine M Ivison Hans-Martin Jäck Peter K Jani Beatriz Jávega Stipan Jonjic Toralf Kaiser Tomas Kalina Thomas Kamradt Stefan H E Kaufmann Baerbel Keller Steven L C Ketelaars Ahad Khalilnezhad Srijit Khan Jan Kisielow Paul Klenerman Jasmin Knopf Hui-Fern Koay Katja Kobow Jay K Kolls Wan Ting Kong Manfred Kopf Thomas Korn Katharina Kriegsmann Hendy Kristyanto Thomas Kroneis Andreas Krueger Jenny Kühne Christian Kukat Désirée Kunkel Heike Kunze-Schumacher Tomohiro Kurosaki Christian Kurts Pia Kvistborg Immanuel Kwok Jonathan Landry Olivier Lantz Paola Lanuti Francesca LaRosa Agnès Lehuen Salomé LeibundGut-Landmann Michael D Leipold Leslie Y T Leung Megan K Levings Andreia C Lino Francesco Liotta Virginia Litwin Yanling Liu Hans-Gustaf Ljunggren Michael Lohoff Giovanna Lombardi Lilly Lopez Miguel López-Botet Amy E Lovett-Racke Erik Lubberts Herve Luche Burkhard Ludewig Enrico Lugli Sebastian Lunemann Holden T Maecker Laura Maggi Orla Maguire Florian Mair Kerstin H Mair Alberto Mantovani Rudolf A Manz Aaron J Marshall Alicia Martínez-Romero Glòria Martrus Ivana Marventano Wlodzimierz Maslinski Giuseppe Matarese Anna Vittoria Mattioli Christian Maueröder Alessio Mazzoni James McCluskey Mairi McGrath Helen M McGuire Iain B McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Stephen D Miller Kingston H G Mills Hans Minderman Jenny Mjösberg Jonni Moore Barry Moran Lorenzo Moretta Tim R Mosmann Susann Müller Gabriele Multhoff Luis Enrique Muñoz Christian Münz Toshinori Nakayama Milena Nasi Katrin Neumann Lai Guan Ng Antonia Niedobitek Sussan Nourshargh Gabriel Núñez José-Enrique O'Connor Aaron Ochel Anna Oja Diana Ordonez Alberto Orfao Eva Orlowski-Oliver Wenjun Ouyang Annette Oxenius Raghavendra Palankar Isabel Panse Kovit Pattanapanyasat Malte Paulsen Dinko Pavlinic Livius Penter Pärt Peterson Christian Peth Jordi Petriz Federica Piancone Winfried F Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Zhiyong Poon Katharina Pracht Immo Prinz Carlo E M Pucillo Sally A Quataert Linda Quatrini Kylie M Quinn Helena Radbruch Tim R D J Radstake Susann Rahmig Hans-Peter Rahn Bartek Rajwa Gevitha Ravichandran Yotam Raz Jonathan A Rebhahn Diether Recktenwald Dorothea Reimer Caetano Reis e Sousa Ester B M Remmerswaal Lisa Richter Laura G Rico Andy Riddell Aja M Rieger J Paul Robinson Chiara Romagnani Anna Rubartelli Jürgen Ruland Armin Saalmüller Yvan Saeys Takashi Saito Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Inga Sandrock Angela Santoni Ramon Bellmàs Sanz Marina Saresella Catherine Sautes-Fridman Birgit Sawitzki Linda Schadt Alexander Scheffold Hans U Scherer Matthias Schiemann Frank A Schildberg Esther Schimisky Andreas Schlitzer Josephine Schlosser Stephan Schmid Steffen Schmitt Kilian Schober Daniel Schraivogel Wolfgang Schuh Thomas Schüler Reiner Schulte Axel Ronald Schulz Sebastian R Schulz Cristiano Scottá Daniel Scott-Algara David P Sester T Vincent Shankey Bruno Silva-Santos Anna Katharina Simon Katarzyna M Sitnik Silvano Sozzani Daniel E Speiser Josef Spidlen Anders Stahlberg Alan M Stall Natalie Stanley Regina Stark Christina Stehle Tobit Steinmetz Hannes Stockinger Yousuke Takahama Kiyoshi Takeda Leonard Tan Attila Tárnok Gisa Tiegs Gergely Toldi Julia Tornack Elisabetta Traggiai Mohamed Trebak Timothy I M Tree Joe Trotter John Trowsdale Maria Tsoumakidou Henning Ulrich Sophia Urbanczyk Willem van de Veen Maries van den Broek Edwin van der Pol Sofie Van Gassen Gert Van Isterdael René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Anouk von Borstel Konrad von Volkmann Ari Waisman Rachael V Walker Paul K Wallace Sa A Wang Xin M Wang Michael D Ward Kirsten A Ward-Hartstonge Klaus Warnatz Gary Warnes Sarah Warth Claudia Waskow James V Watson Carsten Watzl Leonie Wegener Thomas Weisenburger Annika Wiedemann Jürgen Wienands Anneke Wilharm Robert John Wilkinson Gerald Willimsky James B Wing Rieke Winkelmann Thomas H Winkler Oliver F Wirz Alicia Wong Peter Wurst Jennie H M Yang Juhao Yang Maria Yazdanbakhsh Liping Yu Alice Yue Hanlin Zhang Yi Zhao Susanne Maria Ziegler Christina Zielinski Jakob Zimmermann Arturo Zychlinsky

Eur J Immunol 2019 Oct;49(10):1457-1973

Max Planck Institute for Infection Biology, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.201970107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350392PMC
October 2019

Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery.

Eur J Immunol 2019 05 20;49(5):770-781. Epub 2019 Feb 20.

The John Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.20184796
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http://dx.doi.org/10.1002/eji.201847960DOI Listing
May 2019

The TNF Family of Ligands and Receptors: Communication Modules in the Immune System and Beyond.

Physiol Rev 2019 01;99(1):115-160

Department of Infection and Immunity, Experimental and Molecular Immunology, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg ; Odense Research Center for Anaphylaxis, Department of Dermatology and Allergy Center, Odense University Hospital, University of Southern Denmark , Odense , Denmark ; and Life Sciences Research Unit, Molecular Disease Mechanisms Group, University of Luxembourg, Belvaux, Luxembourg.

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https://www.physiology.org/doi/10.1152/physrev.00045.2017
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http://dx.doi.org/10.1152/physrev.00045.2017DOI Listing
January 2019

B-Cell Metabolic Remodeling and Cancer.

Trends Cancer 2018 02 1;4(2):138-150. Epub 2018 Feb 1.

Department of Infection and Immunity, Experimental and Molecular Immunology, Luxembourg Institute of Health, 29 rue Henri Koch, L-4354 Esch-sur-Alzette, Luxembourg; Odense Research Center for Anaphylaxis (ORCA), Department of Dermatology and Allergy Center, Odense University Hospital, University of Southern Denmark, Odense, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.trecan.2017.12.006DOI Listing
February 2018

Reactive Oxygen Species: Involvement in T Cell Signaling and Metabolism.

Trends Immunol 2018 06 13;39(6):489-502. Epub 2018 Feb 13.

Department of Infection and Immunity, Experimental and Molecular Immunology, Luxembourg Institute of Health, L-4354 Esch-sur-Alzette, Luxembourg; Odense Research Center for Anaphylaxis (ORCA), Department of Dermatology and Allergy Center, Odense University Hospital, University of Southern Denmark, Odense, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.it.2018.01.005DOI Listing
June 2018

Survival of the fittest: Cancer challenges T cell metabolism.

Cancer Lett 2018 01 24;412:216-223. Epub 2017 Oct 24.

Department of Infection and Immunity, Experimental and Molecular Immunology, Luxembourg Institute of Health, 29, rue Henri Koch, L-4354 Esch-sur-Alzette, Luxembourg; Odense Research Center for Anaphylaxis (ORCA), Department of Dermatology and Allergy Center, Odense University Hospital, University of Southern Denmark, Odense, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.10.014DOI Listing
January 2018

Glutathione Primes T Cell Metabolism for Inflammation.

Immunity 2017 04;46(4):675-689

Department of Infection and Immunity, Experimental and Molecular Immunology, Luxembourg Institute of Health, Esch-sur-Alzette, L-4354, Luxembourg; Odense Research Center for Anaphylaxis, Department of Dermatology and Allergy Center, Odense University Hospital, University of Southern Denmark, Odense, DK-5000, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.03.019DOI Listing
April 2017

TNF and ROS Crosstalk in Inflammation.

Trends Cell Biol 2016 Apr 12;26(4):249-261. Epub 2016 Jan 12.

Department of Infection and Immunity, Experimental and Molecular Immunology, Luxembourg Institute of Health, 29, rue Henri Koch, 4354 Esch-sur-Alzette, Luxembourg; Odense Research Center for Anaphylaxis (ORCA), Department of Dermatology and Allergy Center, Odense University Hospital, University of Southern Denmark, Odense, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2015.12.002DOI Listing
April 2016

Regulation of tumour necrosis factor signalling: live or let die.

Nat Rev Immunol 2015 Jun;15(6):362-74

1] The Campbell Family Cancer Research Institute, Ontario Cancer Institute, University Health Network, Toronto, Ontario M5G 2M9, Canada. [2] Department of Immunology, University of Toronto, Ontario M5S 1A8, Canada. [3] Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Ontario M5G 1L7, Canada.

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http://dx.doi.org/10.1038/nri3834DOI Listing
June 2015

Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression.

Cancer Cell 2015 Feb 22;27(2):211-22. Epub 2015 Jan 22.

The Campbell Family Institute for Breast Cancer Research, University Health Network, 620 University Avenue, Toronto, ON M5G 2M9, Canada; Department of Medical Biophysics, University Health Network, 620 University Avenue, Toronto, ON M5G 2M9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2014.11.019DOI Listing
February 2015

Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis.

Proc Natl Acad Sci U S A 2015 Jan 12;112(4):1119-24. Epub 2015 Jan 12.

Department of Immunology, University of Toronto, Toronto, Ontario, Canada M5S 1A8; Campbell Family Cancer Research Institute, University Health Network, Toronto, Ontario, Canada M5G 2C1;

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http://dx.doi.org/10.1073/pnas.1423588112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313859PMC
January 2015

Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells.

Proc Natl Acad Sci U S A 2014 Jan 7;111(3):1060-5. Epub 2014 Jan 7.

The Campbell Family Cancer Research Institute, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada M5G 2C1.

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http://dx.doi.org/10.1073/pnas.1323166111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903229PMC
January 2014

Energy-sensitive regulation of Na+/K+-ATPase by Janus kinase 2.

Am J Physiol Cell Physiol 2014 Feb 4;306(4):C374-84. Epub 2013 Dec 4.

Department of Physiology, University of Tübingen, Tübingen, Germany;

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http://dx.doi.org/10.1152/ajpcell.00320.2013DOI Listing
February 2014

Lymphocyte-derived ACh regulates local innate but not adaptive immunity.

Proc Natl Acad Sci U S A 2013 Jan 7;110(4):1410-5. Epub 2013 Jan 7.

Campbell Family Institute for Breast Cancer Research, University Health Network, Toronto, ON, Canada M5G 2C1.

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http://dx.doi.org/10.1073/pnas.1221655110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557089PMC
January 2013

2-Methoxyestradiol inhibits experimental autoimmune encephalomyelitis through suppression of immune cell activation.

Proc Natl Acad Sci U S A 2012 Dec 3;109(51):21034-9. Epub 2012 Dec 3.

Campbell Family Institute for Breast Cancer Research, University Health Network, Toronto, ON, Canada M5G 2C1.

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http://dx.doi.org/10.1073/pnas.1215558110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529073PMC
December 2012

The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells.

J Clin Invest 2012 Dec 1;122(12):4698-709. Epub 2012 Nov 1.

The Campbell Family Cancer Research Institute, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1172/JCI63528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590210PMC
December 2012

Enterohaemorrhagic, but not enteropathogenic, Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha.

Microbiology (Reading) 2011 Oct 28;157(Pt 10):2963-2973. Epub 2011 Jul 28.

Department of Laboratory Medicine and Pathobiology University of Toronto, Medical Sciences Building, 1 King's College Circle, University of Toronto, Toronto, ON M5S 1A8, Canada.

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http://dx.doi.org/10.1099/mic.0.051094-0DOI Listing
October 2011

HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1.

Proc Natl Acad Sci U S A 2010 Feb 22;107(6):2622-7. Epub 2010 Jan 22.

Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute at Princess Margaret Hospital, University Health Network, Toronto, ON M5G 2C1, Canada.

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http://dx.doi.org/10.1073/pnas.0914492107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823890PMC
February 2010

Histone deacetylase inhibitor-induced sensitization to TNFalpha/TRAIL-mediated apoptosis in cervical carcinoma cells is dependent on HPV oncogene expression.

Int J Cancer 2010 Sep;127(6):1384-92

Infektionen und Krebs, Deutsches Krebsforschungszentrum, Abteilung Virale Transformationsmechanismen, Heidelberg, Germany.

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http://doi.wiley.com/10.1002/ijc.25170
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http://dx.doi.org/10.1002/ijc.25170DOI Listing
September 2010

Mitochondrial cell death effectors.

Curr Opin Cell Biol 2009 Dec 12;21(6):871-7. Epub 2009 Oct 12.

The Campbell Family Cancer Research Institute, Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S09550674090016
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http://dx.doi.org/10.1016/j.ceb.2009.09.004DOI Listing
December 2009

Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells.

Proc Natl Acad Sci U S A 2009 Aug 11;106(34):14508-13. Epub 2009 Aug 11.

Division of Immunogenetics, Tumor Immunology Program, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0900457106
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http://dx.doi.org/10.1073/pnas.0900457106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732850PMC
August 2009

Concepts of activated T cell death.

Crit Rev Oncol Hematol 2008 Apr;66(1):52-64

Tumor Immunology Program, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S104084280800013
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http://dx.doi.org/10.1016/j.critrevonc.2008.01.002DOI Listing
April 2008

Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes.

Blood 2007 Dec 21;110(12):3968-77. Epub 2007 Aug 21.

Tumor Immunology Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1182/blood-2007-01-071167DOI Listing
December 2007

In vitro generated human memory-like T cells are CD95 type II cells and resistant towards CD95-mediated apoptosis.

Eur J Immunol 2006 Nov;36(11):2894-903

Tumor Immunology Program, Division of Immunogenetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/eji.200635925DOI Listing
November 2006

How T lymphocytes switch between life and death.

Eur J Immunol 2006 Jul;36(7):1654-8

Tumor Immunology Program, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1002/eji.200636197DOI Listing
July 2006

The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.

J Exp Med 2006 May 8;203(5):1295-305. Epub 2006 May 8.

Division of Immunogenetics, Tumorimmunology Program, German Cancer Research Center, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1084/jem.20051556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121210PMC
May 2006

Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death.

EMBO J 2005 Dec 8;24(24):4279-90. Epub 2005 Dec 8.

Tumor Immunology Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/sj.emboj.7600894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356335PMC
December 2005

c-FLIPR, a new regulator of death receptor-induced apoptosis.

J Biol Chem 2005 Apr 8;280(15):14507-13. Epub 2005 Feb 8.

Division of Immunogenetics, Tumorimmunology Program, German Cancer Research Center, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1074/jbc.M414425200DOI Listing
April 2005

HDAC inhibitors trigger apoptosis in HPV-positive cells by inducing the E2F-p73 pathway.

Oncogene 2004 Jun;23(28):4807-17

Deutsches Krebsforschungszentrum, Forschungsschwerpunkt Angewandte Tumorvirologie, Abteilung Virale Transformationsmechanismen, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1038/sj.onc.1207620DOI Listing
June 2004

Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt.

Hepatology 2004 Mar;39(3):645-54

Tumor Immunology Program, Division of Immunogenetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1002/hep.20138DOI Listing
March 2004