Dirk Arnold

Dirk Arnold

UNVERIFIED PROFILE

Are you Dirk Arnold?   Register this Author

Register author
Dirk Arnold

Dirk Arnold

Publications by authors named "Dirk Arnold"

Are you Dirk Arnold?   Register this Author

100Publications

2051Reads

10Profile Views

Maintenance Olaparib for Germline -Mutated Metastatic Pancreatic Cancer.

N Engl J Med 2019 Jun 2. Epub 2019 Jun 2.

From the Oncology Institute, Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel (T.G.); Hôpital Beaujon (Assistance Publique-Hôpitaux de Paris), Clichy, and University Paris VII, Paris (P.H.); IRCCS Ospedale San Raffaele Scientific Institute, Milan (M.R.), Azienda Ospedaliera Universitaria Integrata Verona, Verona (G.T.), and Fondazione Policlinico Universitario Gemelli IRCCS, Rome (G.T.) - all in Italy; University Hospitals Gasthuisberg and KU Leuven, Leuven, Belgium (E.V.C.); Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona (T.M.); Fox Chase Cancer Center, Philadelphia (M.J.H.); Samsung Medical Center, Sungkyunkwan University School of Medicine (J.-O.P.), and Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine (D.-Y.O.) - both in Seoul, South Korea; University College London Cancer Institute, London (D.H.), and AstraZeneca, Cambridge (D.M.) - both in the United Kingdom; Asklepios Tumorzentrum Hamburg Asklepios Klinik Altona, Hamburg (D.A.), St. Josef-Hospital, Ruhr University Bochum, Bochum (A.R.-S.), and Klinikum rechts der Isar, Department of Internal Medicine II, Technische Universität München, Munich (H.A.) - all in Germany; Memorial Sloan Kettering Cancer Center, New York (E.M.O.); AstraZeneca, Gaithersburg, MD (K.Y.C., G.Y.L.); Merck, Kenilworth, NJ (K.S.); and the University of Chicago, Chicago (H.L.K.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1903387DOI Listing
June 2019

Maximising clinical benefit with adequate patient management beyond the second line in mCRC.

ESMO Open 2019 13;4(2):e000495. Epub 2019 May 13.

Digestive Oncology, University Hospitals Leuven and KU Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/esmoopen-2019-000495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555611PMC
May 2019

Neuromechanical Model of Rat Hindlimb Walking with Two-Layer CPGs.

Biomimetics (Basel) 2019 Mar 1;4(1). Epub 2019 Mar 1.

Department of Mechanical and Materials Engineering, Portland State University, Portland, OR 97207, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/biomimetics4010021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477610PMC
March 2019

Perioperative Systemic Chemotherapy, Cytoreductive Surgery, and Hyperthermic Intraperitoneal Chemotherapy in Patients With Colorectal Peritoneal Metastasis: Results of the Prospective Multicenter Phase 2 COMBATAC Trial.

Clin Colorectal Cancer 2018 12 31;17(4):285-296. Epub 2018 Jul 31.

Department of Surgery, University Medical Center Regensburg, Regensburg, Germany; Department of Surgery, Krankenhaus Barmherzige Brüder Regensburg, Regensburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clcc.2018.07.011DOI Listing
December 2018

Impact of the Localization of the Primary Tumor and RAS/BRAF Mutational Status on Maintenance Strategies After First-line Oxaliplatin, Fluoropyrimidine, and Bevacizumab in Metastatic Colorectal Cancer: Results From the AIO 0207 Trial.

Clin Colorectal Cancer 2018 12 25;17(4):e733-e739. Epub 2018 Jul 25.

Division of Hematology, Oncology and Palliative Care, St. Josef-Hospital Bochum, Ruhr-University, Bochum, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clcc.2018.07.007DOI Listing
December 2018

Impact of primary tumour location on efficacy of bevacizumab plus chemotherapy in metastatic colorectal cancer.

Br J Cancer 2018 Dec 29;119(12):1451-1455. Epub 2018 Nov 29.

University of Southern California, Norris Comprehensive Cancer Center, Keck School of Medicine, 1441 Eastlake Ave, Los Angeles, CA, 90033, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41416-018-0304-6
Publisher Site
http://dx.doi.org/10.1038/s41416-018-0304-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288128PMC
December 2018

Targeted therapy for metastatic colorectal cancer.

Expert Rev Anticancer Ther 2018 10 3;18(10):991-1006. Epub 2018 Aug 3.

n Medical Oncology , Cabrini Hospital and Monash University , Melbourne , Australia.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14737140.2018.1
Publisher Site
http://dx.doi.org/10.1080/14737140.2018.1502664DOI Listing
October 2018

Adjuvant therapy for resected colon cancer 2017, including the IDEA analysis.

Expert Rev Anticancer Ther 2018 04 1;18(4):339-349. Epub 2018 Mar 1.

o Medical Oncology, University of Queensland , Brisbane , Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14737140.2018.1444481DOI Listing
April 2018

Baseline and On-Treatment Markers Determining Prognosis of First-Line Chemotherapy in Combination with Bevacizumab in Patients with Metastatic Colorectal Cancer.

Oncol Res Treat 2017 18;40(1-2):21-26. Epub 2017 Jan 18.

Hubertus Wald Tumor Center, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000454774DOI Listing
September 2017

Method to test the long-term stability of functional electrical stimulation via multichannel electrodes (e.g., applicable for laryngeal pacing) and to define best points for stimulation: in vivo animal analysis.

Eur Arch Otorhinolaryngol 2017 Jan 19;274(1):327-336. Epub 2016 Jul 19.

Division for Motor Research, Pathophysiology and Biomechanics, Department for Trauma-, Hand- and Reconstructive Surgery, University Hospital, Friedrich-Schiller-University Jena, Erfurter Str. 35, 07740, Jena, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00405-016-4202-3DOI Listing
January 2017

Comparison of Constraint-Handling Mechanisms for the (1,λ)-ES on a Simple Constrained Problem.

Evol Comput 2016 16;24(1):1-23. Epub 2014 Oct 16.

Faculty of Computer Science, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4R2

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1162/EVCO_a_00139DOI Listing
December 2016

Effect of Application and Intensity of Bevacizumab-based Maintenance After Induction Chemotherapy With Bevacizumab for Metastatic Colorectal Cancer: A Meta-analysis.

Clin Colorectal Cancer 2016 06 18;15(2):e29-39. Epub 2015 Dec 18.

CUF Hospitals Cancer Centre, Lisbon, Portugal; Hubertus Wald Tumour Centre, University Cancer Centre Hamburg, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clcc.2015.12.005DOI Listing
June 2016

Treatment approach in patients with hyperbilirubinemia secondary to liver metastases in gastrointestinal malignancies: a case series and review of literature.

Ther Adv Med Oncol 2016 May 17;8(3):144-52. Epub 2016 Mar 17.

University Medical Center Hamburg-Eppendorf, Department of Oncology, Hematology, Bone Marrow Transplantation with Section Pneumology, Hubertus Wald Tumor Center, Hamburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1758834016637585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872252PMC
May 2016

Improving patient outcomes with regorafenib for metastatic colorectal cancer - patient selection, dosing, patient education, prophylaxis, and management of adverse events.

Oncol Res Treat 2015 12;38(6):300-8. Epub 2015 May 12.

Interdisciplinary Tumor Center Mannheim, University Hospital Mannheim, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000382067DOI Listing
March 2016

PREFACE.

Appl Radiat Isot 2016 Mar 19;109:2-5. Epub 2016 Jan 19.

Kievermondeveld 74, B-2440 Geel, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.apradiso.2016.01.018DOI Listing
March 2016

Integrating patient reported measures as predictive parameters into decisionmaking about palliative chemotherapy: a pilot study.

BMC Palliat Care 2016 Mar 1;15:25. Epub 2016 Mar 1.

Department of Oncology, Hematology, BMT with Section Pneumology, University Medical Center Hamburg-Eppendorf, Hubertus Wald Tumour Center - University Cancer Center Hamburg, Martinistr. 52, 20246, Hamburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12904-016-0101-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772352PMC
March 2016

Development of a novel larynx pacemaker multichannel array electrode: In vivo animal analysis.

Laryngoscope 2016 Feb 30;126(2):429-36. Epub 2015 Jul 30.

Division for Motor Research, Pathophysiology and Biomechanics, Department for Trauma-, Hand- and Reconstructive Surgery, Jena University Hospital, Jena.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/lary.25512DOI Listing
February 2016

Pre-clinical evaluation of a minimally invasive laryngeal pacemaker system in mini-pig.

Eur Arch Otorhinolaryngol 2016 Jan 12;273(1):151-8. Epub 2015 Aug 12.

Department Otorhinolaryngology, SRH Wald-Klinikum Gera, 07548, Gera, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00405-015-3735-1DOI Listing
January 2016

Maintenance treatment in metastatic colorectal cancer - Authors' reply.

Lancet Oncol 2015 Dec;16(16):e584-5

Klinik für Tumorbiologie, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(15)00471-4DOI Listing
December 2015

Critical evaluation of the scientific content in clinical practice guidelines.

Cancer 2015 Jun 29;121(11):1907-8. Epub 2015 Jan 29.

Guidelines Committee, Subject Editor for Gastrointestinal Cancer, European Society for Medical Oncology, Viganello-Lugano, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.29261DOI Listing
June 2015

On the behaviour of the (1, λ)-ES for conically constrained linear problems.

Authors:
Dirk V Arnold

Evol Comput 2014 14;22(3):503-23. Epub 2014 Jul 14.

Faculty of Computer Science, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4R2

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1162/EVCO_a_00125DOI Listing
April 2015

Challenges in the multidisciplinary management of stage IV colon and rectal cancer.

Expert Rev Gastroenterol Hepatol 2015 Mar 5;9(3):317-26. Epub 2014 Sep 5.

Department for General- and Visceral Surgery, Hospital Barmherzige Brueder, Pruefeninger Str. 86, 93049 Regensburg Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/17474124.2015.957273DOI Listing
March 2015

Current opinion on optimal systemic treatment for metastatic colorectal cancer: outcome of the ACTG/AGITG expert meeting ECCO 2013.

Expert Rev Anticancer Ther 2014 Dec 20;14(12):1477-93. Epub 2014 Aug 20.

The Queen Elizabeth Hospital, Adelaide Colorectal Tumour Group and University of Adelaide, Adeaide, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/14737140.2014.949678DOI Listing
December 2014

Maintenance treatment with the immunomodulator MGN1703, a Toll-like receptor 9 (TLR9) agonist, in patients with metastatic colorectal carcinoma and disease control after chemotherapy: a randomised, double-blind, placebo-controlled trial.

J Cancer Res Clin Oncol 2014 Sep 10;140(9):1615-24. Epub 2014 May 10.

Department of Internal Medicine IV, Oncology/Hematology, University Clinic Halle (Saale), Center for Cell and Gene Therapy, Martin Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06120, Halle, Germany,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00432-014-1682-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131138PMC
September 2014

The role of relative lymphocyte count as a biomarker for the effect of catumaxomab on survival in malignant ascites patients: results from a phase II/III study.

Clin Cancer Res 2014 Jun 8;20(12):3348-57. Epub 2014 Apr 8.

Authors' Affiliations: Department of Abdominal, Vascular and Transplant Surgery, Cologne-Merheim Medical Center, Witten-Herdecke University, Cologne; University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Neovii (formerly Fresenius) Biotech GmbH; TRION Pharma GmbH, Munich, Germany; and Nottingham University NHS Trust, Nottingham, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-13-2351DOI Listing
June 2014

Anal cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up.

Radiother Oncol 2014 Jun 16;111(3):330-9. Epub 2014 Jun 16.

Klinik für Tumorbiologie, Freiburg, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radonc.2014.04.013DOI Listing
June 2014

Docetaxel, oxaliplatin and capecitabine (TEX regimen) in patients with metastatic gastric or gastro-esophageal cancer: results of a multicenter phase I/II study.

Acta Oncol 2014 Mar 12;53(3):392-8. Epub 2013 Sep 12.

Hubertus Wald Tumor Center, University Cancer Center Hamburg, Department of Oncology, Hematology, BMT with Section Pneumology, University Medical Center Hamburg-Eppendorf , Hamburg , Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/0284186X.2013.833346DOI Listing
March 2014

Gastric cancer: ESMO-ESSO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Radiother Oncol 2014 Jan;110(1):189-94

Department of Medical Oncology, Tumor Biology Clinic, Albert Ludwigs University, Freiburg, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radonc.2013.09.015DOI Listing
January 2014

Resampling versus repair in evolution strategies applied to a constrained linear problem.

Authors:
Dirk V Arnold

Evol Comput 2013 31;21(3):389-411. Epub 2012 Aug 31.

Faculty of Computer Science, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4R2.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1162/EVCO_a_00088DOI Listing
November 2013

New developments in the second-line treatment of metastatic colorectal cancer: potential place in therapy.

Drugs 2013 Jun;73(9):883-91

Tumor Biology Center Freiburg, Breisacher Str. 117, 79106 Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40265-013-0076-5DOI Listing
June 2013

Precise measurement and calculation of coincidence summing corrections for point and linear sources.

Appl Radiat Isot 2012 Sep 27;70(9):2107-11. Epub 2012 Feb 27.

Physics Department, University of Bucharest, P.O. Box MG-11, 077125 Magurele, Romania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.apradiso.2012.02.082DOI Listing
September 2012

PTEN deletion is rare but often homogeneous in gastric cancer.

J Clin Pathol 2012 Aug 25;65(8):693-8. Epub 2012 May 25.

Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jclinpath-2011-200525DOI Listing
August 2012

Personalized treatment of colorectal cancer.

Onkologie 2012 20;35 Suppl 1:42-8. Epub 2012 Jan 20.

Hubertus Wald Tumour Center, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000334821DOI Listing
May 2012

Prevalence and patterns of renal involvement in imaging of malignant lymphoproliferative diseases.

Acta Radiol 2012 Apr 27;53(3):343-8. Epub 2012 Jan 27.

Department of Radiology, Martin-Luther-University Halle-Wittenberg, Halle, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1258/ar.2011.110523DOI Listing
April 2012

Measurements of (60)Co in massive steel samples exposed to the Hiroshima atomic bomb explosion.

Health Phys 2012 Apr;102(4):400-9

European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, EC-JRC-IRMM, Retieseweg 111, 2440 Geel, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HP.0b013e31823a172eDOI Listing
April 2012

Oxaliplatin: a review of approved uses.

Expert Opin Pharmacother 2012 Jan;13(1):125-37

University Cancer Center Hamburg, University Hospital Hamburg-Eppendorf (UKE), Hubertus Wald Tumor Center, Martinistr. 52, 20246 Hamburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/14656566.2012.643870DOI Listing
January 2012

First-line treatment of pancreatic cancer patients with the combination of 5-fluorouracil/folinic acid plus gemcitabine: a multicenter phase II trial by the CONKO-study group.

Cancer Chemother Pharmacol 2011 Nov 15;68(5):1173-8. Epub 2011 Mar 15.

Charité Centrum für Tumormedizin, Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00280-011-1602-3DOI Listing
November 2011

Multimodal treatment approaches for peritoneal carcinosis in colorectal cancer.

Dtsch Arztebl Int 2011 Nov 25;108(47):802-8. Epub 2011 Nov 25.

Klinik für Allgemein- und Viszeralchirurgie Krankenhaus Barmherzige Brüder Prüfeninger Str. 8693049 Regensburg,

View Article

Download full-text PDF

Source
https://www.aerzteblatt.de/10.3238/arztebl.2011.0802
Publisher Site
http://dx.doi.org/10.3238/arztebl.2011.0802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240780PMC
November 2011

On the behaviour of evolution strategies optimising cigar functions.

Evol Comput 2010 31;18(4):661-82. Epub 2010 Aug 31.

Faculty of Computer Science, Dalhousie University, Halifax, Nova Scotia, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1162/EVCO_a_00023DOI Listing
March 2011

[Clinical trials and personalized medicine in oncology?].

Onkologie 2010 16;33 Suppl 7:25-9. Epub 2010 Sep 16.

Klinik für Onkologie, Hämatologie, KMT mit Sektion Pneumologie, Hamburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000319739DOI Listing
February 2011

The role of peri-operative treatment in resectable liver metastases of colorectal cancer.

Ther Adv Med Oncol 2010 Nov;2(6):389-98

Martin-Luther-University Halle/Wittenberg, Department of Internal Medicine IV, Halle, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1758834010375095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126028PMC
November 2010

[Adjuvant therapy in colon cancer].

Onkologie 2010 23;33 Suppl 4:2-7. Epub 2010 Apr 23.

Medizinische Universitätsklinik Knappschaftskrankenhaus, Ruhr-Universität Bochum, Deutschland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000308436DOI Listing
August 2010

[Specific treatment situations in metastatic colorectal cancer].

Onkologie 2010 23;33 Suppl 4:8-18. Epub 2010 Apr 23.

Klinik für Innere Medizin IV, Onkologie/Hämatologie, Universitätsklinikum Halle, Saale, Deutschland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000308447DOI Listing
August 2010

[Treatment of rectal cancer].

Onkologie 2010 23;33 Suppl 4:19-23. Epub 2010 Apr 23.

Klinik für Strahlentherapie und Onkologie, Universität Frankfurt am Main, Deutschland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000308449DOI Listing
August 2010

Breast plasmacytoma.

Acta Radiol 2010 Jun;51(5):498-504

Department of Radiology, Martin-Luther-University of Halle-Wittenberg, Halle, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/02841851003712924DOI Listing
June 2010

Targeted treatments in colorectal cancer: state of the art and future perspectives.

Gut 2010 Jun;59(6):838-58

Department of Internal Medicine IV, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Strasse 40, D-06120 Halle (Saale), Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/gut.2009.196006DOI Listing
June 2010

Peri-operative chemotherapy for the treatment of resectable liver metastases from colorectal cancer: A systematic review and meta-analysis of randomized trials.

BMC Cancer 2010 Jun 21;10:309. Epub 2010 Jun 21.

Department of Internal Medicine, Knappschaftskrankenhaus Bochum Langendreer, University of Bochum, Bochum, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2407-10-309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908098PMC
June 2010