Dion Kaiserman

Dion Kaiserman

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Dion Kaiserman

Dion Kaiserman

Publications by authors named "Dion Kaiserman"

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Detection of Active Granzyme A in NK92 Cells with Fluorescent Activity-Based Probe.

J Med Chem 2020 Mar 16;63(6):3359-3369. Epub 2020 Mar 16.

Wrocław University of Science and Technology, Department of Chemical Biology and Bioimaging, Wyb. Wyspiańskiego 29, 50-370 Wroclaw, Poland.

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http://dx.doi.org/10.1021/acs.jmedchem.9b02042DOI Listing
March 2020

SerpinB1 controls encephalitogenic T helper cells in neuroinflammation.

Proc Natl Acad Sci U S A 2019 10 23;116(41):20635-20643. Epub 2019 Sep 23.

The Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1905762116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789640PMC
October 2019

A Novel Serpin Regulatory Mechanism: SerpinB9 IS REVERSIBLY INHIBITED BY VICINAL DISULFIDE BOND FORMATION IN THE REACTIVE CENTER LOOP.

J Biol Chem 2016 Feb 15;291(7):3626-38. Epub 2015 Dec 15.

From the Department of Biochemistry & Molecular Biology, Biomedicine Discovery Institute, Monash University Clayton, Clayton, Victoria 3800 Australia and

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http://dx.doi.org/10.1074/jbc.M115.699298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751400PMC
February 2016

A natural genetic variant of granzyme B confers lethality to a common viral infection.

PLoS Pathog 2014 Dec 11;10(12):e1004526. Epub 2014 Dec 11.

Immunology and Virology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Crawley, Western Australia, Australia; Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia, Australia.

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http://dx.doi.org/10.1371/journal.ppat.1004526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263754PMC
December 2014

Absence of SERPINB6A causes sensorineural hearing loss with multiple histopathologies in the mouse inner ear.

Am J Pathol 2013 Jul 10;183(1):49-59. Epub 2013 May 10.

Department of Otolaryngology, University of Melbourne, East Melbourne, Australia.

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http://dx.doi.org/10.1016/j.ajpath.2013.03.009DOI Listing
July 2013

Detection of human and mouse granzyme B activity in cell extracts.

Methods Mol Biol 2012 ;844:251-60

Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-61779-527-5_18DOI Listing
May 2012

Intracellular production of recombinant serpins in yeast.

Methods Enzymol 2011 ;501:1-12

Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/B978-0-12-385950-1.00001-8DOI Listing
March 2012

Predicting serpin/protease interactions.

Methods Enzymol 2011 ;501:237-73

Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/B978-0-12-385950-1.00012-2DOI Listing
March 2012

Serpins flex their muscle: II. Structural insights into target peptidase recognition, polymerization, and transport functions.

J Biol Chem 2010 Aug 24;285(32):24307-12. Epub 2010 May 24.

From the Department of Biochemistry and Molecular Biology and ARC Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1074/jbc.R110.141408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915666PMC
August 2010

Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems.

J Biol Chem 2010 Aug 24;285(32):24299-305. Epub 2010 May 24.

Department of Pediatrics and Cell Biology and Physiology, Children's Hospital of Pittsburgh and Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15201, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.R110.112771
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http://dx.doi.org/10.1074/jbc.R110.112771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915665PMC
August 2010

Expression, purification and characterization of recombinant Z alpha(1)-antitrypsin--the most common cause of alpha(1)-antitrypsin deficiency.

Protein Expr Purif 2009 Dec 23;68(2):226-32. Epub 2009 Jun 23.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Vic. 3800, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S104659280900150
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http://dx.doi.org/10.1016/j.pep.2009.06.011DOI Listing
December 2009

The effects of exosite occupancy on the substrate specificity of thrombin.

Arch Biochem Biophys 2009 Sep 26;489(1-2):48-54. Epub 2009 Jul 26.

Department of Biochemistry & Molecular Biology, Monash University, Clayton, Vic. 3800, Australia.

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http://dx.doi.org/10.1016/j.abb.2009.07.012DOI Listing
September 2009

Antihemostatic activity of human granzyme B mediated by cleavage of von Willebrand factor.

J Biol Chem 2008 Aug 24;283(33):22498-504. Epub 2008 Jun 24.

Department of Biochemistry and Molecular Biology, Monash University, Clayton 3800, Victoria, Australia.

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http://dx.doi.org/10.1074/jbc.M709080200DOI Listing
August 2008

Mechanisms of serpin dysfunction in disease.

Expert Rev Mol Med 2006 Dec 11;8(31):1-19. Epub 2006 Dec 11.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1017/S1462399406000184DOI Listing
December 2006

The major human and mouse granzymes are structurally and functionally divergent.

J Cell Biol 2006 Nov;175(4):619-30

Department of Biochemistry and Molecular Biology and 2Victorian Bioinformatics Consortium, Monash University, Victoria 3800, Australia.

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http://dx.doi.org/10.1083/jcb.200606073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064598PMC
November 2006

Elucidation of the substrate specificity of the C1s protease of the classical complement pathway.

J Biol Chem 2005 Nov 16;280(47):39510-4. Epub 2005 Sep 16.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1074/jbc.M506131200DOI Listing
November 2005

Analysis of vertebrate genomes suggests a new model for clade B serpin evolution.

BMC Genomics 2005 Nov 23;6:167. Epub 2005 Nov 23.

Department of Biochemistry & Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1186/1471-2164-6-167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1308813PMC
November 2005

Enhancement of DNA vaccine potency by coadministration of a tumor antigen gene and DNA encoding serine protease inhibitor-6.

Cancer Res 2004 Jan;64(1):400-5

Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1158/0008-5472.can-03-1475DOI Listing
January 2004