Dihua Yu

Dihua Yu

UNVERIFIED PROFILE

Are you Dihua Yu?   Register this Author

Register author
Dihua Yu

Dihua Yu

Publications by authors named "Dihua Yu"

Are you Dihua Yu?   Register this Author

100Publications

2391Reads

13Profile Views

Proteomics analysis of the matrisome from MC38 experimental mouse liver metastases.

Am J Physiol Gastrointest Liver Physiol 2019 Nov 23;317(5):G625-G639. Epub 2019 Sep 23.

Cancer Research United Kingdom/Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpgi.00014.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879896PMC
November 2019

Suppressing immunotherapy by organ-specific tumor microenvironments: what is in the brain?

Cell Biosci 2019 7;9:82. Epub 2019 Oct 7.

Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13578-019-0349-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781341PMC
October 2019

Brain Metastasis Organotropism.

Cold Spring Harb Perspect Med 2019 Sep 23. Epub 2019 Sep 23.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/cshperspect.a037242DOI Listing
September 2019

The importance of developing therapies targeting the biological spectrum of metastatic disease.

Clin Exp Metastasis 2019 Aug 17;36(4):305-309. Epub 2019 May 17.

Division of Hematology and Oncology, Department of Medicine, Department of Otolaryngology, Tisch Cancer Institute, Black Family Stem Cell Institute, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10585-019-09972-3
Publisher Site
http://dx.doi.org/10.1007/s10585-019-09972-3DOI Listing
August 2019

Sphingosine Kinase 1 Signaling Promotes Metastasis of Triple-Negative Breast Cancer.

Cancer Res 2019 Aug 25;79(16):4211-4226. Epub 2019 Jun 25.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-18-3803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697620PMC
August 2019

Exosomes in cancer development, metastasis, and immunity.

Authors:
Lin Zhang Dihua Yu

Biochim Biophys Acta Rev Cancer 2019 04 30;1871(2):455-468. Epub 2019 Apr 30.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbcan.2019.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542596PMC
April 2019

Oncogenic Kinase-Induced PKM2 Tyrosine 105 Phosphorylation Converts Nononcogenic PKM2 to a Tumor Promoter and Induces Cancer Stem-like Cells.

Cancer Res 2018 05 12;78(9):2248-2261. Epub 2018 Feb 12.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-17-2726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932213PMC
May 2018

Working together to make AJCR stronger.

Authors:
Dihua Yu

Am J Cancer Res 2018 10;8(1). Epub 2018 Jan 10.

Department of Molecular & Cellular Oncology, The University of Texas MD Anderson Cancer CenterHouston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794716PMC
January 2018

Targeting Aberrant p70S6K Activation for Estrogen Receptor-Negative Breast Cancer Prevention.

Cancer Prev Res (Phila) 2017 Nov 6;10(11):641-650. Epub 2017 Sep 6.

Department of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1940-6207.CAPR-17-0106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668174PMC
November 2017

14-3-3ζ loss leads to neonatal lethality by microRNA-126 downregulation-mediated developmental defects in lung vasculature.

Cell Biosci 2017 2;7:58. Epub 2017 Nov 2.

Department of Molecular and Cellular Oncology, Unit 108, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 USA.

View Article

Download full-text PDF

Source
http://cellandbioscience.biomedcentral.com/articles/10.1186/
Publisher Site
http://dx.doi.org/10.1186/s13578-017-0186-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667492PMC
November 2017

14-3-3ζ loss impedes oncogene-induced mammary tumorigenesis and metastasis by attenuating oncogenic signaling.

Am J Cancer Res 2017 1;7(8):1654-1664. Epub 2017 Aug 1.

Department of Molecular & Cellular Oncology, The University of Texas MD Anderson Cancer CenterHouston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574938PMC
August 2017

Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis.

J Vis Exp 2017 02 8(120). Epub 2017 Feb 8.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3791/55085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409267PMC
February 2017

Brain metastasis: Unique challenges and open opportunities.

Biochim Biophys Acta Rev Cancer 2017 Jan 6;1867(1):49-57. Epub 2016 Dec 6.

Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbcan.2016.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5272787PMC
January 2017

Deubiquitination and Stabilization of PD-L1 by CSN5.

Cancer Cell 2016 Dec 17;30(6):925-939. Epub 2016 Nov 17.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Unit 108, 1515 Holcombe Boulevard, Houston, TX 77030, USA; Graduate School of Biomedical Sciences, The University of Texas Health Science Center, Houston, TX 77030, USA; Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University, Taichung 404, Taiwan; Department of Biotechnology, Asia University, Taichung 413, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2016.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171205PMC
December 2016

Advances in decoding breast cancer brain metastasis.

Cancer Metastasis Rev 2016 12;35(4):677-684

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10555-016-9638-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215972PMC
December 2016

Downregulation of GLUT4 contributes to effective intervention of estrogen receptor-negative/HER2-overexpressing early stage breast disease progression by lapatinib.

Am J Cancer Res 2016 1;6(5):981-95. Epub 2016 May 1.

Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer CenterHouston, TX 77030, USA; Cancer Biology Program, The University of Texas Graduate School of Biomedical Sciences at HoustonHouston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889714PMC
June 2016

Selective expression of constitutively active pro-apoptotic protein BikDD gene in primary mammary tumors inhibits tumor growth and reduces tumor initiating cells.

Am J Cancer Res 2015 15;5(12):3624-34. Epub 2015 Nov 15.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer CenterHouston, Texas, 77030, USA; Graduate School of Biomedical Sciences, The University of Texas Health Science Center at HoustonHouston, Texas, 77030, USA; Center of Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University and HospitalTaichung, 404, Taiwan; Department of Biotechnology, Asia UniversityTaichung, 413, Taiwan.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731636PMC
February 2016

PI3K-independent mTOR activation promotes lapatinib resistance and IAP expression that can be effectively reversed by mTOR and Hsp90 inhibition.

Cancer Biol Ther 2015 ;16(3):402-11

a Department of Molecular and Cellular Oncology ; The University of Texas MD Anderson Cancer Center ; Houston , TX USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15384047.2014.1002693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623386PMC
January 2016

Fluoxetine induces cytotoxic endoplasmic reticulum stress and autophagy in triple negative breast cancer.

World J Clin Oncol 2015 Dec;6(6):299-311

Michelle Bowie, Siya Lem, Abigail Hoffman, Shraddha Desai, Amira Carter, Adrian Ambrose, Victoria Seewaldt, Catherine Ibarra Drendall, Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, NC 27710, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5306/wjco.v6.i6.299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675916PMC
December 2015

Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer.

Cancer Res 2015 Nov 17;75(22):4863-75. Epub 2015 Sep 17.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Center for Molecular Medicine, China Medical University, Taichung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-14-2345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651709PMC
November 2015

Cooperativity of oncogenic K-ras and downregulated p16/INK4A in human pancreatic tumorigenesis.

PLoS One 2014 16;9(7):e101452. Epub 2014 Jul 16.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101452PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100754PMC
March 2015

14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2.

Cancer Cell 2015 Feb;27(2):177-92

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; The University of Texas Graduate School of Biomedical Sciences, Houston, TX 77030, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2014.11.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325275PMC
February 2015

Definition of PKC-α, CDK6, and MET as therapeutic targets in triple-negative breast cancer.

Cancer Res 2014 Sep 26;74(17):4822-35. Epub 2014 Jun 26.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas. Graduate Institute for Cancer Biology and Center for Molecular Medicine, China Medical University, Taichung, Taiwan. Department of Biotechnology, Asia University, Taichung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-14-0584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154991PMC
September 2014

MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer.

Sci Signal 2014 Jul 29;7(336):ra71. Epub 2014 Jul 29.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX 77030, USA. Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University, Taichung 404, Taiwan. Department of Biotechnology, Asia University, Taichung 413, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scisignal.2005076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161976PMC
July 2014

S6K1 promotes invasiveness of breast cancer cells in a model of metastasis of triple-negative breast cancer.

Am J Transl Res 2014 18;6(4):361-76. Epub 2014 Jul 18.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center Houston, Texas ; The University of Texas Graduate School of Biomedical Sciences at Houston Houston, Texas ; Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University Taichung 402, Taiwan ; Department of Biotechnology, Asia University Taichung, Taiwan.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113498PMC
July 2014

Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis.

PLoS One 2013 5;8(9):e73406. Epub 2013 Sep 5.

Department of Molecular and Cellular Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America ; Cancer Biology Program, the University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073406PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764163PMC
June 2014

Biomarker-guided sequential targeted therapies to overcome therapy resistance in rapidly evolving highly aggressive mammary tumors.

Cell Res 2014 May 28;24(5):542-59. Epub 2014 Mar 28.

1] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA [2] Cancer Biology Program, Graduate School of Biomedical Sciences-Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/cr.2014.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011340PMC
May 2014

Enhanced PI3K p110α signaling confers acquired lapatinib resistance that can be effectively reversed by a p110α-selective PI3K inhibitor.

Mol Cancer Ther 2014 Jan 18;13(1):60-70. Epub 2013 Nov 18.

Corresponding Author: Dihua Yu, Department of Molecular and Cellular Oncology, MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-13-0518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902650PMC
January 2014

SRC family kinases as novel therapeutic targets to treat breast cancer brain metastases.

Cancer Res 2013 Sep 1;73(18):5764-74. Epub 2013 Aug 1.

Authors' Affiliations: Departments of Molecular and Cellular Oncology, Neurosurgery, and Pathology, The University of Texas MD Anderson Cancer Center; Cancer Biology Program, Graduate School of Biomedical Sciences-Houston, Houston, Texas; Women's Cancers Section, Laboratory of Molecular Pharmacology, National Cancer Institute, Bethesda, Maryland; and Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-12-1803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781592PMC
September 2013

Growth factor signaling in metastasis: current understanding and future opportunities.

Cancer Metastasis Rev 2012 Dec;31(3-4):479-91

Department of Molecular & Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10555-012-9380-xDOI Listing
December 2012

Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer.

Cancer Res 2012 Sep 6;72(17):4417-28. Epub 2012 Jul 6.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-12-1339-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556997PMC
September 2012

Targeting Src family kinases in anti-cancer therapies: turning promise into triumph.

Trends Pharmacol Sci 2012 Mar 9;33(3):122-8. Epub 2011 Dec 9.

Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tips.2011.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675659PMC
March 2012

Evidence that GTP-binding domain but not catalytic domain of transglutaminase 2 is essential for epithelial-to-mesenchymal transition in mammary epithelial cells.

Breast Cancer Res 2012 Jan 6;14(1):R4. Epub 2012 Jan 6.

Department of Experimental Therapeutics, The University of Texas M.D., Anderson Cancer Center, 1901 East Road, 4SCR3,1006, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/bcr3085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496119PMC
January 2012

Nucleolin protein interacts with microprocessor complex to affect biogenesis of microRNAs 15a and 16.

J Biol Chem 2011 Dec 2;286(51):44095-103. Epub 2011 Nov 2.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M111.265439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243533PMC
December 2011

Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells.

PLoS One 2011 8;6(6):e20701. Epub 2011 Jun 8.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020701PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110765PMC
October 2011

Cancer cell migration: integrated roles of matrix mechanics and transforming potential.

PLoS One 2011 27;6(5):e20355. Epub 2011 May 27.

Department of Biomedical Engineering, The University of Texas at Austin, Austin, Texas, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020355PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103552PMC
September 2011

p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs.

Nat Cell Biol 2011 Mar 20;13(3):317-23. Epub 2011 Feb 20.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb2173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075845PMC
March 2011

Microenvironment determinants of brain metastasis.

Cell Biosci 2011 Feb 25;1(1). Epub 2011 Feb 25.

Department of Molecular and Cellular Oncology, The University of Texas M,D, Anderson Cancer Center, Houston, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/2045-3701-1-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125212PMC
February 2011

High-resolution fiber-optic microendoscopy for in situ cellular imaging.

J Vis Exp 2011 Jan 11(47). Epub 2011 Jan 11.

Department of Bioengineering, Rice University, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3791/2306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182629PMC
January 2011

Activation of p21(CIP1/WAF1) in mammary epithelium accelerates mammary tumorigenesis and promotes lung metastasis.

Biochem Biophys Res Commun 2010 Dec 30;403(1):103-7. Epub 2010 Oct 30.

Department of Molecular and Cellular Oncology, The University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2010.10.126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001223PMC
December 2010

14-3-3ζ as a prognostic marker and therapeutic target for cancer.

Expert Opin Ther Targets 2010 Dec;14(12):1343-54

The University of Texas M. D. Anderson Cancer Center, Department of Molecular and Cellular Oncology, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://www.tandfonline.com/doi/full/10.1517/14728222.2010.53
Publisher Site
http://dx.doi.org/10.1517/14728222.2010.531011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017465PMC
December 2010

PTEN, PIK3CA, p-AKT, and p-p70S6K status: association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer.

Am J Pathol 2010 Oct 2;177(4):1647-56. Epub 2010 Sep 2.

Department of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2353/ajpath.2010.090885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947262PMC
October 2010

Cancer cell stiffness: integrated roles of three-dimensional matrix stiffness and transforming potential.

Biophys J 2010 Oct;99(7):2048-57

Department of Biomedical Engineering, The University of Texas, Austin, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bpj.2010.07.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042573PMC
October 2010

Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells.

PLoS One 2010 Oct 12;5(10):e13390. Epub 2010 Oct 12.

Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013390PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953521PMC
October 2010

PI(3)king apart PTEN's role in cancer.

Clin Cancer Res 2010 Sep 8;16(17):4325-30. Epub 2010 Jul 8.

Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-09-2990DOI Listing
September 2010

Molecular predictors of response to trastuzumab and lapatinib in breast cancer.

Nat Rev Clin Oncol 2010 Feb 22;7(2):98-107. Epub 2009 Dec 22.

Department of Breast Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030-4009, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrclinonc.2009.216DOI Listing
February 2010

Upregulation of neutrophil gelatinase-associated lipocalin by ErbB2 through nuclear factor-kappaB activation.

Cancer Res 2009 Dec;69(24):9163-8

Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-09-2483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794902PMC
December 2009

14-3-3zeta/tau heterodimers regulate Slingshot activity in migrating keratinocytes.

Biochem Biophys Res Commun 2009 Jun 14;383(4):450-4. Epub 2009 Apr 14.

Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Tarry 8-716, 303 E. Chicago Avenue, Chicago, IL 60611, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2009.04.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727353PMC
June 2009

Breast cancer metastasis: challenges and opportunities.

Cancer Res 2009 Jun 26;69(12):4951-3. Epub 2009 May 26.

Department of Molecular and Cellular Oncology, University of Texas, M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-09-0099DOI Listing
June 2009

14-3-3zeta overexpression defines high risk for breast cancer recurrence and promotes cancer cell survival.

Cancer Res 2009 Apr 24;69(8):3425-32. Epub 2009 Mar 24.

Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-08-2765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671640PMC
April 2009

Oxygen sensor boosts growth factor signaling.

Nat Med 2009 Mar;15(3):246-7

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm0309-246DOI Listing
March 2009

Mitotic deregulation by survivin in ErbB2-overexpressing breast cancer cells contributes to Taxol resistance.

Clin Cancer Res 2009 Feb;15(4):1326-34

Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-08-0954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663973PMC
February 2009

Ph.D. Training in cancer biology.

Cancer Res 2008 Nov;68(22):9122-4

Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-08-2626DOI Listing
November 2008

14-3-3 zeta down-regulates p53 in mammary epithelial cells and confers luminal filling.

Cancer Res 2008 Mar;68(6):1760-7

Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-07-3177DOI Listing
March 2008

Molecular mechanisms of erbB2-mediated breast cancer chemoresistance.

Authors:
Ming Tan Dihua Yu

Adv Exp Med Biol 2007 ;608:119-29

Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-0-387-74039-3_9DOI Listing
December 2007

Novel approaches for chemosensitization of breast cancer cells: the E1A story.

Adv Exp Med Biol 2007 ;608:144-69

Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-0-387-74039-3_11DOI Listing
December 2007

Preclinical testing of clinically applicable strategies for overcoming trastuzumab resistance caused by PTEN deficiency.

Clin Cancer Res 2007 Oct;13(19):5883-8

Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-06-2837DOI Listing
October 2007

High prevalence of p53 exon 4 mutations in soft tissue sarcoma.

Cancer 2007 Jun;109(11):2323-33

Department of Surgical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.22680DOI Listing
June 2007

Adenoviral-Vector Based siRNA for Mutant K-ras as a Promising Tool for Lung Cancer Gene Therapy: A License to Kill.

Authors:
Jing Lu Dihua Yu

Cancer Biol Ther 2006 Dec 28;5(12):1724-5. Epub 2006 Dec 28.

Department of Molecular and Cellular Onocology, MD Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cbt.5.12.3761DOI Listing
December 2006

Cytoplasmic expression of p21CIP1/WAF1 is correlated with IKKbeta overexpression in human breast cancers.

Int J Oncol 2006 Nov;29(5):1103-10

Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
November 2006

Wild-type p53 inhibits nuclear factor-kappaB-induced matrix metalloproteinase-9 promoter activation: implications for soft tissue sarcoma growth and metastasis.

Mol Cancer Res 2006 Nov 31;4(11):803-10. Epub 2006 Oct 31.

Departments of 1 Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-06-0201DOI Listing
November 2006

Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer.

Nat Clin Pract Oncol 2006 May;3(5):269-80

Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston 77030-4009, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncponc0509DOI Listing
May 2006

Selective inhibition of ErbB2-overexpressing breast cancer in vivo by a novel TAT-based ErbB2-targeting signal transducers and activators of transcription 3-blocking peptide.

Cancer Res 2006 Apr;66(7):3764-72

Departments of Surgical Oncology and Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-05-2747DOI Listing
April 2006

Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells.

Mol Cancer Ther 2006 Feb;5(2):317-28

Section of Molecular Hematology and Therapy, Department of Blood and Marrow Transplantation, The University of Texas M.D. Anderson Cancer Center, Unit 448, 1400 Holcombe Boulevard, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-05-0350DOI Listing
February 2006

A knotty turnabout?: Akt1 as a metastasis suppressor.

Cancer Cell 2005 Dec;8(6):437-9

Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2005.11.006DOI Listing
December 2005

Mechanisms of trastuzumab resistance and their clinical implications.

Ann N Y Acad Sci 2005 Nov;1059:70-5

Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1196/annals.1339.026DOI Listing
November 2005

ErbB2 promotes Src synthesis and stability: novel mechanisms of Src activation that confer breast cancer metastasis.

Cancer Res 2005 Mar;65(5):1858-67

Department of Surgical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-04-2353DOI Listing
March 2005

Transcriptional repression of protein kinase Calpha via Sp1 by wild type p53 is involved in inhibition of multidrug resistance 1 P-glycoprotein phosphorylation.

J Biol Chem 2005 Feb 24;280(6):4825-33. Epub 2004 Nov 24.

Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M407450200
Publisher Site
http://dx.doi.org/10.1074/jbc.M407450200DOI Listing
February 2005

Expression of receptor tyrosine kinases epidermal growth factor receptor and HER-2/neu in synovial sarcoma.

Cancer 2005 Feb;103(4):830-8

Department of Pathology, University of Michigan Health System, Ann Arbor, Michigan 48109-0602, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.20847DOI Listing
February 2005