Dietrich A Stephan

Dietrich A Stephan

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Dietrich A Stephan

Dietrich A Stephan

Publications by authors named "Dietrich A Stephan"

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An APOE-independent cis-eSNP on chromosome 19q13.32 influences tau levels and late-onset Alzheimer's disease risk.

Neurobiol Aging 2018 06 3;66:178.e1-178.e8. Epub 2018 Jan 3.

Tanz Centre for Research in Neurodegenerative Diseases, and Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.12.027DOI Listing
June 2018

Whole exome sequencing in females with autism implicates novel and candidate genes.

Int J Mol Sci 2015 Jan 7;16(1):1312-35. Epub 2015 Jan 7.

Departments of Psychiatry & Behavioral Sciences, University of Kansas Medical Center, 3901 Rainbow Boulevard, MS 4015, Kansas City, KS 66160, USA.

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http://dx.doi.org/10.3390/ijms16011312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307305PMC
January 2015

Diagnostics for personalized medicine: what will change in the era of large-scale genomics studies?

Per Med 2013 Nov;10(8):835-848

Silicon Valley Biosystems, 950 Tower Lane, 11th Floor, Foster City, CA 94404, USA.

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https://www.futuremedicine.com/doi/10.2217/pme.13.82
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http://dx.doi.org/10.2217/pme.13.82DOI Listing
November 2013

Genetic determinants of athletic performance.

Recent Pat DNA Gene Seq 2012 Dec;6(3):175-9

Silicon Valley Biosystems, Navigenics, Menlo Park, CA 95026, USA.

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December 2012

The implications of ENCODE for diagnostics.

Nat Biotechnol 2012 Nov;30(11):1064-5

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http://dx.doi.org/10.1038/nbt.2418DOI Listing
November 2012

Why life science needs its own Silicon Valley.

Harv Bus Rev 2012 Jul-Aug;90(7-8):25-7

Pennsylavania State University, Smeal College of Business, USA.

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August 2012

Autism and increased paternal age related changes in global levels of gene expression regulation.

PLoS One 2011 Feb 17;6(2):e16715. Epub 2011 Feb 17.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016715PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040743PMC
February 2011

Alterations in gene expression of human vascular endothelial cells associated with nanotopographic cues.

Biomaterials 2010 Dec 15;31(34):8882-8. Epub 2010 Sep 15.

Department of Chemical and Biological Engineering, School of Engineering, University of Wisconsin, Madison, WI, United States.

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http://dx.doi.org/10.1016/j.biomaterials.2010.08.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622050PMC
December 2010

Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1 (hypermethylated in cancer 1).

J Biol Chem 2009 Jul 12;284(31):20927-35. Epub 2009 Jun 12.

CNRS UMR 8161 Institut de Biologie de Lille, Université de Lille NORD de France, Institut Pasteur de Lille, 59017 Lille, France.

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http://dx.doi.org/10.1074/jbc.M109.022350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742858PMC
July 2009

Gene expression profiling of TGFbeta2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling.

Exp Eye Res 2009 Jun 18;88(6):1020-32. Epub 2009 Jan 18.

Institute of Human Anatomy and Embryology, University of Regensburg, Universitätsstr. 31, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1016/j.exer.2009.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014319PMC
June 2009

SNP imputation in association studies.

Nat Biotechnol 2009 Apr;27(4):349-51

International Computer Science Institute, Berkeley, CA, USA.

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http://dx.doi.org/10.1038/nbt0409-349DOI Listing
April 2009

Maximizing power in association studies.

Nat Biotechnol 2009 Mar;27(3):255-6

International Computer Science Institute, Berkeley, CA 94704, USA.

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http://dx.doi.org/10.1038/nbt0309-255DOI Listing
March 2009

Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.

J Neural Transm (Vienna) 2008 Nov 7;115(11):1573-85. Epub 2008 Oct 7.

ADHD Clinical Research Program, Molecular and Clinical Psychobiology, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Fuechsleinstr. 15, 97080, Wuerzburg, Germany.

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http://dx.doi.org/10.1007/s00702-008-0119-3DOI Listing
November 2008

Elevated amounts of myocilin in the aqueous humor of transgenic mice cause significant changes in ocular gene expression.

Exp Eye Res 2008 Sep 17;87(3):257-67. Epub 2008 Jun 17.

Institute of Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1016/j.exer.2008.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572563PMC
September 2008

Refinement of 2q and 7p loci in a large multiplex NTD family.

Birth Defects Res A Clin Mol Teratol 2008 Jun;82(6):441-52

Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1002/bdra.20462DOI Listing
June 2008

Unraveling autism.

Am J Hum Genet 2008 Jan;82(1):7-9

Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1016/j.ajhg.2007.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253980PMC
January 2008

Chromosomal abnormality at 6p25.1-25.3 identifies a susceptibility locus for hypothalamic hamartoma associated with epilepsy.

Epilepsy Res 2007 Jun 18;75(1):70-3. Epub 2007 May 18.

Epilepsy Center and Division of Pediatric Neurology, Barrow Neurological Institute and Children's Health Center, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.

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http://dx.doi.org/10.1016/j.eplepsyres.2007.04.002DOI Listing
June 2007

A generic research paradigm for identification and validation of early molecular diagnostics and new therapeutics in common disorders.

Mol Diagn Ther 2007 ;11(1):1-14

Neurogenomics Division, The Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1007/BF03256218DOI Listing
April 2007

A novel role for cyclooxygenase-2 in regulating vascular channel formation by human breast cancer cells.

Breast Cancer Res 2006 ;8(6):R69

Department of Biochemistry and Molecular Biology, Mayo Clinic, 13400 E, Shea Blvd, Scottsdale, Arizona 85259, USA.

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http://dx.doi.org/10.1186/bcr1626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797025PMC
February 2007

Genetics, transcriptomics, and proteomics of Alzheimer's disease.

J Clin Psychiatry 2006 Apr;67(4):652-70

Division of Psychiatry Research, University of Zurich, Zurich, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259384PMC
http://dx.doi.org/10.4088/jcp.v67n0418DOI Listing
April 2006

Cognitive dysfunction in NF1 knock-out mice may result from altered vesicular trafficking of APP/DRD3 complex.

BMC Neurosci 2006 Mar 8;7:22. Epub 2006 Mar 8.

Developmental Neurogenetics Laboratory, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.

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http://bmcneurosci.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2202-7-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434756PMC
March 2006

Cyclooxygenase-2 inhibitors in human skeletal fracture healing.

Orthopedics 2006 Mar;29(3):259-61

Hospital for Special Surgery, New York, NY, USA.

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March 2006

Expression profiling reveals multiple myelin alterations in murine succinate semialdehyde dehydrogenase deficiency.

J Inherit Metab Dis 2006 Feb;29(1):143-56

Developmental Neurogenetics Research Laboratory, Barrow Neurological Institute, Phoenix, Arizona, USA.

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http://dx.doi.org/10.1007/s10545-006-0247-6DOI Listing
February 2006

Microarray and protein analysis of human pterygium.

Mol Vis 2006 Jan 23;12:55-64. Epub 2006 Jan 23.

National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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January 2006

Rare variants of the gene encoding the potassium chloride co-transporter 3 are associated with bipolar disorder.

Int J Neuropsychopharmacol 2005 Dec 5;8(4):495-504. Epub 2005 Aug 5.

Clinical and Molecular Psychobiology, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Germany.

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http://dx.doi.org/10.1017/S1461145705005821DOI Listing
December 2005

The Autism Genome Project: goals and strategies.

Am J Pharmacogenomics 2005 ;5(4):233-46

Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, USA.

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October 2005

Identification of disease causing loci using an array-based genotyping approach on pooled DNA.

BMC Genomics 2005 Sep 30;6:138. Epub 2005 Sep 30.

Neurogenomics Division, Translational Genomics Research Institute (TGen), Phoenix, Arizona 85004, USA.

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http://dx.doi.org/10.1186/1471-2164-6-138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262713PMC
September 2005

Dissection of the sets of genes that control the behavior of biglycan-deficient pre-osteoblasts using oligonucleotide microarrays.

Bone 2005 Aug;37(2):192-203

Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S875632820500149
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http://dx.doi.org/10.1016/j.bone.2005.04.006DOI Listing
August 2005

Discovery and development of biomarkers of neurological disease.

Drug Discov Today 2005 Mar;10(5):326-34

Neurogenomics Division, The Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1016/S1359-6446(04)03353-7DOI Listing
March 2005

Applications of whole-genome high-density SNP genotyping.

Expert Rev Mol Diagn 2005 Mar;5(2):159-70

The Translational Genomics Research Institute, Neurogenomics Division, 445 North Fifth Street, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1586/14737159.5.2.159DOI Listing
March 2005

Gene and protein expression changes in human trabecular meshwork cells treated with transforming growth factor-beta.

Invest Ophthalmol Vis Sci 2004 Nov;45(11):4023-34

Section on Aging and Ocular Disease, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1167/iovs.04-0535DOI Listing
November 2004

Inter-platform comparability of microarrays in acute lymphoblastic leukemia.

BMC Genomics 2004 Sep 23;5:71. Epub 2004 Sep 23.

Research Center for Genetic Medicine, Children's National Medical Center, Institute of Biomedical Sciences, George Washington University Medical Center, Washington, D.C. 20037, USA.

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http://dx.doi.org/10.1186/1471-2164-5-71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC522810PMC
September 2004

Biomarker identification in neurologic diseases: improving diagnostics and therapeutics.

Expert Rev Mol Diagn 2004 May;4(3):361-75

The Translational Genomics Research Institute, 400 N. Fifth Street, Suite 1600, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1586/14737159.4.3.361DOI Listing
May 2004

Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure.

Invest Ophthalmol Vis Sci 2004 Apr;45(4):1247-58

Laboratory of Molecular and Developmental Biology, National Eye Institute, Bethesda, Maryland 20814-9692, USA.

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http://dx.doi.org/10.1167/iovs.03-1123DOI Listing
April 2004

Gene arrays and temporal patterns of drug response: corticosteroid effects on rat liver.

Funct Integr Genomics 2003 Dec 20;3(4):171-9. Epub 2003 Aug 20.

Department of Biological Sciences, SUNY at Buffalo, 107 Hochstetter Hall, Buffalo, NY 14260, USA.

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http://dx.doi.org/10.1007/s10142-003-0090-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207265PMC
December 2003

Genome-wide homozygosity mapping localizes a gene for autosomal recessive non-progressive infantile ataxia to 20q11-q13.

Hum Genet 2003 Aug 17;113(3):293-5. Epub 2003 Jun 17.

Department of Audiology, Bispebjerg Hospital, Bispebjerg Bakke 23, DK-2400, Copenhagen NV, Denmark.

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http://dx.doi.org/10.1007/s00439-003-0967-8DOI Listing
August 2003

Correlation of expression of BP1, a homeobox gene, with estrogen receptor status in breast cancer.

Breast Cancer Res 2003 22;5(4):R82-7. Epub 2003 Apr 22.

Department of Biochemistry and Molecular Biology, The George Washington University Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1186/bcr602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC165014PMC
August 2003

Effects of prostaglandin analogues on human ciliary muscle and trabecular meshwork cells.

Invest Ophthalmol Vis Sci 2003 May;44(5):1945-52

Laboratory of Mechanisms of Ocular Diseases, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1167/iovs.02-0920DOI Listing
May 2003

Integrating microarrays into disease-gene identification strategies.

Expert Rev Mol Diagn 2003 May;3(3):375-85

Neurobehavioral Branch, Neurogenomics Program, TGen, The Translational Genomics Research Institute, 400 North Fifth Street, Suite 1600, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1586/14737159.3.3.375DOI Listing
May 2003

Overexpression of the EGFR/FKBP12/HIF-2alpha pathway identified in childhood astrocytomas by angiogenesis gene profiling.

Cancer Res 2003 Apr;63(8):1865-70

Center for Cancer Research, Children's Research Institute, Washington, DC 20010, USA.

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April 2003

Genome-wide analyses of steroid- and radiation-triggered programmed cell death in Drosophila.

Curr Biol 2003 Feb;13(4):350-7

Center for Biosystems Research, University of Maryland Biotechnology Institute and Department of Medicine, University of Maryland, College Park, MD 20742, USA.

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http://dx.doi.org/10.1016/s0960-9822(03)00085-xDOI Listing
February 2003

Nuclear factor 90 mediates activation of the cellular antiviral expression cascade.

AIDS Res Hum Retroviruses 2002 May;18(8):591-604

Department of Biochemistry and Molecular Biology, George Washington University School of Medicine, Washington, D.C. 20037, USA.

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http://www.liebertpub.com/doi/10.1089/088922202753747941
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http://dx.doi.org/10.1089/088922202753747941DOI Listing
May 2002