Publications by authors named "Dietmar Pfeifer"

100Publications

TGF-β Signaling Regulates SLC8A3 Expression and Prevents Oxidative Stress in Developing Midbrain Dopaminergic and Dorsal Raphe Serotonergic Neurons.

Int J Mol Sci 2020 Apr 15;21(8). Epub 2020 Apr 15.

Institute of Anatomy and Cell Biology, Department of Molecular Embryology, Faculty of Medicine, University of Freiburg, Albertstrasse 17, 79104 Freiburg, Germany.

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http://dx.doi.org/10.3390/ijms21082735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216069PMC
April 2020

A novel conditional NPM-ALK-driven model of CD30+ T-cell lymphoma mediated by a translational stop cassette.

Oncogene 2020 Feb 21;39(9):1904-1913. Epub 2019 Nov 21.

Department of Hematology, Oncology and Stem Cell Transplantation, Medical Center, Faculty of Medicine, University of Freiburg, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41388-019-1058-1DOI Listing
February 2020

Boehmite Nanofillers in Epoxy Oligosiloxane Resins: Influencing the Curing Process by Complex Physical and Chemical Interactions.

Materials (Basel) 2019 May 9;12(9). Epub 2019 May 9.

Federal Institute for Material Research and Testing (BAM), 12205 Berlin, Germany.

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http://dx.doi.org/10.3390/ma12091513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540208PMC
May 2019

PIM1 inhibition effectively enhances plerixafor-induced HSC mobilization by counteracting CXCR4 upregulation and blocking CXCL12 secretion.

Leukemia 2019 05 28;33(5):1296-1301. Epub 2019 Feb 28.

Department of Hematology and Oncology, Freiburg University Medical Center, Albert-Ludwigs-University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41375-019-0428-6DOI Listing
May 2019

Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation.

Leukemia 2019 04 23;33(4):945-956. Epub 2018 Nov 23.

Division of Hematology, Oncology and Stem Cell Transplantation, Department of Internal Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41375-018-0293-8DOI Listing
April 2019

Droplet digital PCR for the simultaneous analysis of minimal residual disease and hematopoietic chimerism after allogeneic cell transplantation.

Clin Chem Lab Med 2019 04;57(5):641-647

Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg, Faculty of Medicine, Freiburg, Germany.

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http://dx.doi.org/10.1515/cclm-2018-0827DOI Listing
April 2019

Silencing of TGFβ signalling in microglia results in impaired homeostasis.

Nat Commun 2018 10 1;9(1):4011. Epub 2018 Oct 1.

Institute for Anatomy and Cell Biology, Department of Molecular Embryology, Faculty of Medicine, University of Freiburg, 79104, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41467-018-06224-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167353PMC
October 2018

Multivariate multiple test procedures based on nonparametric copula estimation.

Biom J 2019 01 12;61(1):40-61. Epub 2018 Jul 12.

Institute for Statistics, University of Bremen, Bibliothekstraße 1, D-28359, Bremen, Germany.

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http://dx.doi.org/10.1002/bimj.201700205DOI Listing
January 2019

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 Apr;24(4):526

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http://dx.doi.org/10.1038/nm0418-526cDOI Listing
April 2018

Biosynthesis and Characterization of Zearalenone-14-Sulfate, Zearalenone-14-Glucoside and Zearalenone-16-Glucoside Using Common Fungal Strains.

Toxins (Basel) 2018 03 1;10(3). Epub 2018 Mar 1.

Institute of Food Chemistry, Hamburg School of Food Science, University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany.

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http://dx.doi.org/10.3390/toxins10030104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869392PMC
March 2018

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 03 12;24(3):282-291. Epub 2018 Feb 12.

Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/nm.4484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029618PMC
March 2018

Inflammatory Pathways Regulated by Tumor Necrosis Receptor-Associated Factor 1 Protect From Metabolic Consequences in Diet-Induced Obesity.

Circ Res 2018 03 22;122(5):693-700. Epub 2018 Jan 22.

From the Cardiology and Angiology I, University Heart Center and Medical Center (N.A.M., C.C., B.D., N.H., K.P., T.M., F.W., P.S., I.H., T.H., C.v.z.M., C.B., A.Z., D.W.), Faculty of Biology (N.A.M.), Department of Radiology, Medical Physics, Medical Center (D.v.E.), Hematology and Oncology (D.P.), and Department of Urology (R.S.), University of Freiburg, Germany; Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA (K.B., A.B.P., E.E., K.L., D.W.); Neurosurgery, University of Erlangen, Germany (B.S.); Center for Cardiovascular Research (U.K.) and Department of Endocrinology & Metabolism, Center for Cardiovascular Research (CCR), Germany (S.B.), Charité-Universitätsmedizin Berlin, Germany; and Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Partner Site Berlin, Germany (S.B.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.312055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834385PMC
March 2018

Cell-free DNA characteristics and chimerism analysis in patients after allogeneic cell transplantation.

Clin Biochem 2018 Feb 24;52:137-141. Epub 2017 Nov 24.

Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg, Faculty of Medicine, Freiburg, Germany.

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http://dx.doi.org/10.1016/j.clinbiochem.2017.11.015DOI Listing
February 2018

C. elegans DAF-16/FOXO interacts with TGF-ß/BMP signaling to induce germline tumor formation via mTORC1 activation.

PLoS Genet 2017 May 26;13(5):e1006801. Epub 2017 May 26.

Bioinformatics and Molecular Genetics, Faculty of Biology, University of Freiburg, Freiburg, Baden-Wuerttemberg, Germany.

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http://dx.plos.org/10.1371/journal.pgen.1006801
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1006801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467913PMC
May 2017

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.

Cell 2016 11 27;167(5):1264-1280.e18. Epub 2016 Oct 27.

Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; Center of Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.09.054DOI Listing
November 2016

Calmodulin Regulated Spectrin Associated Protein 1 mRNA is Directly Regulated by miR-126 in Primary Human Osteoblasts.

J Cell Biochem 2017 07 5;118(7):1756-1763. Epub 2017 Jan 5.

Departments of Plastic and Hand Surgery, University of Freiburg Medical Center, Freiburg, 79106, Germany.

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http://dx.doi.org/10.1002/jcb.25838DOI Listing
July 2017

Mechanochemically Induced Conversion of Crystalline Benzamide Polymorphs by Seeding.

Angew Chem Int Ed Engl 2016 11 20;55(46):14281-14285. Epub 2016 Oct 20.

BAM Federal Institute for Materials Research and Testing, Richard-Willstätter-Str. 11, 12489, Berlin, Germany.

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http://dx.doi.org/10.1002/anie.201607358DOI Listing
November 2016

Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD.

Blood 2016 07 24;128(3):427-39. Epub 2016 May 24.

Starzl Transplantation Institute and Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1182/blood-2015-12-684142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957164PMC
July 2016

The Hsp70 homolog Ssb and the 14-3-3 protein Bmh1 jointly regulate transcription of glucose repressed genes in Saccharomyces cerevisiae.

Nucleic Acids Res 2016 07 21;44(12):5629-45. Epub 2016 Mar 21.

Institute of Biochemistry and Molecular Biology, ZBMZ, University of Freiburg, D-79104 Freiburg, Germany BIOSS Centre for Biological Signaling Studies, University of Freiburg, D-79104 Freiburg, Germany

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http://dx.doi.org/10.1093/nar/gkw168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937304PMC
July 2016

Sensitive and accurate quantification of JAK2 V617F mutation in chronic myeloproliferative neoplasms by droplet digital PCR.

Ann Hematol 2016 Apr 1;95(5):739-44. Epub 2016 Mar 1.

Department of Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1007/s00277-016-2623-0DOI Listing
April 2016

A Resource for the Transcriptional Signature of Bona Fide Trophoblast Stem Cells and Analysis of Their Embryonic Persistence.

Stem Cells Int 2015 14;2015:218518. Epub 2015 Dec 14.

Renal Department, Centre for Clinical Research, University Medical Centre, Breisacher Strasse 66, 79106 Freiburg, Germany; Institute of Experimental and Clinical Pharmacology and Toxicology, University of Freiburg, Freiburg, Germany; BIOSS, Centre for Biological Signalling Studies, Albert Ludwigs University, Freiburg, Germany.

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http://dx.doi.org/10.1155/2015/218518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691490PMC
January 2016

Transcriptomic Changes in Osteoblasts Following Endothelial Cell-Cocultivation Suggest a Role of Extracellular Matrix in Cellular Interaction.

J Cell Biochem 2016 08 21;117(8):1869-79. Epub 2016 Jan 21.

Department of Plastic and Hand Surgery, University Hospital of Erlangen, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1002/jcb.25486DOI Listing
August 2016

Identification of a blood-borne miRNA signature of synovial sarcoma.

Mol Cancer 2015 Aug 7;14:151. Epub 2015 Aug 7.

Department of Plastic and Hand Surgery, University Medical Center Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1186/s12943-015-0424-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528907PMC
August 2015

MicroRNA-155-deficient dendritic cells cause less severe GVHD through reduced migration and defective inflammasome activation.

Blood 2015 Jul 13;126(1):103-12. Epub 2015 May 13.

Department of Hematology and Oncology, Freiburg University Medical Center, Centre for Biological Signalling Studies BIOSS, Albert-Ludwigs-University, Freiburg, Germany.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-12-61
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http://dx.doi.org/10.1182/blood-2014-12-617258DOI Listing
July 2015

In vitro phase I metabolism of cis-zearalenone.

Chem Res Toxicol 2014 Nov 15;27(11):1972-8. Epub 2014 Oct 15.

Department of Analytical Chemistry; Reference Materials, Federal Institute for Materials Research and Testing (BAM) , Richard-Willstaetter-Strasse 11, 12489 Berlin, Germany.

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http://dx.doi.org/10.1021/tx500312gDOI Listing
November 2014

MiR-146a regulates the TRAF6/TNF-axis in donor T cells during GVHD.

Blood 2014 Oct 9;124(16):2586-95. Epub 2014 Sep 9.

Department of Hematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Center, Centre for Biological Signaling Studies, Albert Ludwigs University Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1182/blood-2014-04-569046DOI Listing
October 2014

Genetic targets of hydrogen sulfide in ventilator-induced lung injury--a microarray study.

PLoS One 2014 15;9(7):e102401. Epub 2014 Jul 15.

Department of Anaesthesiology and Intensive Care Medicine, University Medical Center Freiburg, Freiburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102401PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099342PMC
December 2015

PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1).

Mol Cancer Ther 2014 May 21;13(5):1231-45. Epub 2014 Mar 21.

Authors' Affiliations: Department of Hematology/Oncology; Centre of Chronic Immunodeficiency, University Medical Centre Freiburg; Faculty of Biology; BIOSS Centre for Biological Signaling Studies, University of Freiburg, Freiburg, Germany; Department of Biomedicine, University Hospital Basel, Basel, Switzerland; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School; Department of Cancer Biology, Dana-Faber Cancer Institute, Boston, Massachusetts; and Department of Hematology, Leiden University Medical Centre, Leiden, the Netherlands.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0575-TDOI Listing
May 2014

mRNA and miRNA analyses in cytologically positive endobronchial ultrasound-guided transbronchial needle aspiration: implications for molecular staging in lung cancer patients.

Cancer Cytopathol 2014 Apr 26;122(4):292-8. Epub 2014 Feb 26.

Department of Thoracic Surgery, Lung Clinic Merheim, University Medical Center Witten/Herdecke, Köln, Germany.

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http://dx.doi.org/10.1002/cncy.21398DOI Listing
April 2014

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric imaging of synthetic polymer sample spots prepared using ionic liquid matrices.

Rapid Commun Mass Spectrom 2014 Mar;28(5):489-98

Federal Institute for Materials Research and Testing (BAM), Richard-Willstätter-Strasse 11, D-12489, Berlin, Germany.

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http://dx.doi.org/10.1002/rcm.6810DOI Listing
March 2014

Insulin-like growth factor-1 receptor (IGF1R) as a novel target in chronic lymphocytic leukemia.

Blood 2013 Aug 17;122(9):1621-33. Epub 2013 Jul 17.

Department of Hematology/Oncology, University Medical Center Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1182/blood-2013-02-484386DOI Listing
August 2013

The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells.

Dev Biol 2013 Aug 3;380(2):286-98. Epub 2013 May 3.

Institute for Anatomy and Cell Biology, Department of Molecular Embryology, Albert-Ludwigs-University, Freiburg, Germany.

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http://dx.doi.org/10.1016/j.ydbio.2013.04.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544970PMC
August 2013

Decitabine induces very early in vivo DNA methylation changes in blasts from patients with acute myeloid leukemia.

Leuk Res 2013 Feb 15;37(2):190-6. Epub 2012 Nov 15.

Division Epigenomics and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.leukres.2012.10.015DOI Listing
February 2013

Endogenous transforming growth factor-beta promotes quiescence of primary microglia in vitro.

Glia 2013 Feb 12;61(2):287-300. Epub 2012 Oct 12.

Institute for Anatomy and Cell Biology, Department of Molecular Embryology, Albert-Ludwigs-University, Freiburg, Germany.

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http://dx.doi.org/10.1002/glia.22435DOI Listing
February 2013

MeDIP coupled with a promoter tiling array as a platform to investigate global DNA methylation patterns in AML cells.

Leuk Res 2013 Jan 11;37(1):102-11. Epub 2012 Oct 11.

Division of Hematology/Oncology, Department of Medicine, University Medical Center Freiburg, Germany.

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http://dx.doi.org/10.1016/j.leukres.2012.09.014DOI Listing
January 2013

Immune response as a possible mechanism of long-lasting disease control in spontaneous remission of MLL/AF9-positive acute myeloid leukemia.

Ann Hematol 2012 Jan 29;91(1):27-32. Epub 2011 Sep 29.

Department of Hematology and Oncology, University of Freiburg Medical Center, Hugstetter Straße 55, 79106 Freiburg, Germany.

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http://dx.doi.org/10.1007/s00277-011-1332-yDOI Listing
January 2012

Genome-wide profiling in AML patients relapsing after allogeneic hematopoietic cell transplantation.

Biol Blood Marrow Transplant 2011 Oct 23;17(10):1450-1459.e1. Epub 2011 Jul 23.

Section of Allogeneic Stem Cell Transplantation, Department of Hematology/Oncology, Freiburg University Medical Center, Freiburg, Germany.

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http://dx.doi.org/10.1016/j.bbmt.2011.07.012DOI Listing
October 2011

Definition and characterization of the systemic T-cell dysregulation in untreated indolent B-cell lymphoma and very early CLL.

Blood 2011 Apr 26;117(14):3836-46. Epub 2011 Jan 26.

Department of Hematology/Oncology, University Medical Center Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1182/blood-2010-07-299321DOI Listing
April 2011