Publications by authors named "Dietmar Lohmann"

65Publications

Differentiation Protocol for 3D Retinal Organoids, Immunostaining and Signal Quantitation.

Curr Protoc Stem Cell Biol 2020 Dec;55(1):e120

Institute of Human Genetics, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1002/cpsc.120DOI Listing
December 2020

The impact of RB1 genotype on incidence of second tumours in heritable retinoblastoma.

Eur J Cancer 2020 Jul 17;133:47-55. Epub 2020 May 17.

Institute of Human Genetics, University Duisburg-Essen, Essen, Germany; Eye Oncogenetics Research Group, University Hospital Essen, Essen, Germany; German Consortium for Translational Cancer Research (DKTK), Partner Site Essen, and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejca.2020.04.005DOI Listing
July 2020

Psychosocial impact of prognostic genetic testing in uveal melanoma patients: a controlled prospective clinical observational study.

BMC Psychol 2020 Jan 31;8(1). Epub 2020 Jan 31.

Department of Psychosomatic Medicine and Psychotherapy, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany.

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http://dx.doi.org/10.1186/s40359-020-0371-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995105PMC
January 2020

GNAQ Q209R Mutations Are Highly Specific for Circumscribed Choroidal Hemangioma.

Cancers (Basel) 2019 Jul 22;11(7). Epub 2019 Jul 22.

Department of Pathology, University Hospital Essen, University Duisburg-Essen, Hufelandstr. 55, 45147 Essen, Germany.

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http://dx.doi.org/10.3390/cancers11071031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679048PMC
July 2019

Retinoblastoma with late metastatic spread-a case report.

Pediatr Blood Cancer 2019 06 5;66(6):e27656. Epub 2019 Feb 5.

Hopp Children's Cancer Center (KiTZ), Heidelberg University Hospital, Heidelberg, Germany.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/pbc.27656
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http://dx.doi.org/10.1002/pbc.27656DOI Listing
June 2019

Ectopic intracranial retinoblastoma in a 3.5-month-old infant without eye involvement and without evidence of heritability.

Pediatr Blood Cancer 2019 05 2;66(5):e27599. Epub 2019 Jan 2.

Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.

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http://doi.wiley.com/10.1002/pbc.27599
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http://dx.doi.org/10.1002/pbc.27599DOI Listing
May 2019

Author Correction: The landscape of genomic alterations across childhood cancers.

Nature 2018 07;559(7714):E10

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41586-018-0167-2DOI Listing
July 2018

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

The Interdisciplinary Diagnosis and Treatment of Intraocular Tumors.

Dtsch Arztebl Int 2018 02;115(7):106-111

Department of Ophthalmology, Tumor Center Western Germany, Essen University Hospital; Department of Internal Medicine (Tumor Research), Tumor Center Western Germany, Essen University Hospital; Department of Pediatrics III, Tumor Center Western Germany, Essen University Hospital; Institute for Human Genetics, Tumor Center Western Germany, Essen University Hospital.

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http://dx.doi.org/10.3238/arztebl.2018.0106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842342PMC
February 2018

The landscape of genomic alterations across childhood cancers.

Nature 2018 03 28;555(7696):321-327. Epub 2018 Feb 28.

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature25480DOI Listing
March 2018

Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.

Am J Med Genet A 2017 Apr 7;173(4):1017-1037. Epub 2017 Feb 7.

Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/ajmg.a.38142DOI Listing
April 2017

Psychosocial impact of prognostic genetic testing in the care of uveal melanoma patients: protocol of a controlled prospective clinical observational study.

BMC Cancer 2016 07 7;16:408. Epub 2016 Jul 7.

Clinic for Psychosomatic Medicine and Psychotherapy, LVR Hospital Essen, University of Duisburg-Essen, Virchowstr.174, 45147, Essen, Germany.

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http://dx.doi.org/10.1186/s12885-016-2479-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936050PMC
July 2016

How Eye-Preserving Therapy Affects Long-Term Overall Survival in Heritable Retinoblastoma Survivors.

J Clin Oncol 2016 09 5;34(26):3183-8. Epub 2016 Jul 5.

Petra Temming, Marina Arendt, Anja Viehmann, Lewin Eisele, Claudia H.D. Le Guin, Michael M. Schündeln, Eva Biewald, Jennifer Mäusert, Regina Wieland, Norbert Bornfeld, Wolfgang Sauerwein, Dietmar R. Lohmann, and Karl-Heinz Jöckel, University Hospital Essen, Essen; Petra Temming, Dietmar R. Lohmann, and Karl-Heinz Jöckel, German Consortium for Translational Cancer Research, Heidelberg; and Angelika Eggert, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1200/JCO.2015.65.4012DOI Listing
September 2016

Comparing the Prognostic Value of BAP1 Mutation Pattern, Chromosome 3 Status, and BAP1 Immunohistochemistry in Uveal Melanoma.

Am J Surg Pathol 2016 06;40(6):796-805

*Institute of Neuropathology †Institute of Human Genetics §Department of Opthalmology ∥Institute of Pathology ‡Center for Medical Biotechnology, Microbiology II, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1097/PAS.0000000000000645DOI Listing
June 2016

Pediatric second primary malignancies after retinoblastoma treatment.

Pediatr Blood Cancer 2015 Oct 13;62(10):1799-804. Epub 2015 May 13.

Eye Oncogenetics Research Group, University Hospital Essen, Essen, Germany.

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http://dx.doi.org/10.1002/pbc.25576DOI Listing
October 2015

Acrofacial Dysostosis, Cincinnati Type, a Mandibulofacial Dysostosis Syndrome with Limb Anomalies, Is Caused by POLR1A Dysfunction.

Am J Hum Genet 2015 May 23;96(5):765-74. Epub 2015 Apr 23.

Division of Human Genetics, Department of Pediatrics, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, MLC 4006, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.ajhg.2015.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570288PMC
May 2015

Neoadjuvant/adjuvant treatment of high-risk retinoblastoma: a report from the German Retinoblastoma Referral Centre.

Br J Ophthalmol 2015 Jul 12;99(7):949-53. Epub 2015 Jan 12.

Department of Pediatric Oncology and Hematology, University Hospital Essen, Essen, Germany German Cancer Consortium (DKTK), Heidelberg, Germany Translational Neuro-Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Germany German Cancer Research Center (DKFZ), Heidelberg, Germany Centre for Medical Biotechnology, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1136/bjophthalmol-2014-306222DOI Listing
July 2015

Hereditary Diffuse Infiltrating Retinoblastoma.

Ophthalmic Genet 2016 3;37(1):95-7. Epub 2014 Jun 3.

e Department of Ophthalmology , Vision Institute - IPEPO, Federal University of São Paulo , São Paulo , Brazil.

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http://www.tandfonline.com/doi/full/10.3109/13816810.2014.92
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http://dx.doi.org/10.3109/13816810.2014.921315DOI Listing
September 2016

Autosomal recessive POLR1D mutation with decrease of TCOF1 mRNA is responsible for Treacher Collins syndrome.

Genet Med 2014 Sep 6;16(9):720-4. Epub 2014 Mar 6.

1] Service de Génétique Médicale, Hôpitaux Universitaires de Strasbourg, CHU de Hautepierre, Strasbourg, France [2] Laboratoire de Génétique Médicale, INSERM U1112, Faculté de Médecine, Université de Strasbourg, Strasbourg, France [3] Current affiliation: Service de Génétique, CHU la Réunion, Hôpital Félix Guyon, Saint-Denis, France.

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http://dx.doi.org/10.1038/gim.2014.12DOI Listing
September 2014

The origin of the RB1 imprint.

PLoS One 2013 25;8(11):e81502. Epub 2013 Nov 25.

Institut für Humangenetik, Universitätsklinikum Essen, Essen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0081502PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839921PMC
August 2014

BAP1 germline mutation in two first grade family members with uveal melanoma.

Br J Ophthalmol 2014 Feb 1;98(2):224-7. Epub 2013 Nov 1.

Department of Ophthalmology, University of Regensburg, Germany.

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http://dx.doi.org/10.1136/bjophthalmol-2013-303814DOI Listing
February 2014

Human PPP1R26P1 functions as cis-repressive element in mouse Rb1.

PLoS One 2013 3;8(9):e74159. Epub 2013 Sep 3.

Institut für Humangenetik, Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074159PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760807PMC
May 2014

Chemoreduction improves eye retention in patients with retinoblastoma: a report from the German Retinoblastoma Reference Centre.

Br J Ophthalmol 2013 Oct 17;97(10):1277-83. Epub 2013 Jul 17.

Department of Paediatric Oncology and Haematology, University Hospital Essen, , Essen, Germany.

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http://dx.doi.org/10.1136/bjophthalmol-2013-303452DOI Listing
October 2013

Ultradeep sequencing detects GNAQ and GNA11 mutations in cell-free DNA from plasma of patients with uveal melanoma.

Cancer Med 2013 Apr 14;2(2):208-15. Epub 2013 Feb 14.

Department of Ophthalmology, Faculty of Medicine, University Duisburg-Essen Essen, Germany.

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http://dx.doi.org/10.1002/cam4.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639659PMC
April 2013

Trilateral retinoblastoma in a patient with Peutz-Jeghers syndrome.

Am J Med Genet A 2013 May 5;161A(5):1096-100. Epub 2013 Mar 5.

Department of Molecular Pathology, Canterbury Health Laboratories, Christchurch, New Zealand.

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http://dx.doi.org/10.1002/ajmg.a.35748DOI Listing
May 2013

Sporadic unilateral retinoblastoma or first sign of bilateral disease?

Br J Ophthalmol 2013 Apr 26;97(4):475-80. Epub 2013 Jan 26.

Department of Paediatric Haematology and Oncology, University Hospital Essen, Hufelandstrasse 55, Essen 45122, Germany.

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http://dx.doi.org/10.1136/bjophthalmol-2012-302666DOI Listing
April 2013

Retinoblastoma tumorigenesis: genetic and epigenetic changes walk hand in hand.

Future Oncol 2012 May;8(5):525-8

Eye Oncogenetics Research Group, Department of Human Genetics, Essen, Germany.

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http://dx.doi.org/10.2217/fon.12.41DOI Listing
May 2012

EFS shows biallelic methylation in uveal melanoma with poor prognosis as well as tissue-specific methylation.

BMC Cancer 2011 Aug 26;11:380. Epub 2011 Aug 26.

Institut für Humangenetik, Universitätsklinikum Essen, Hufelandstr, 55, 45157 Essen, Germany.

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http://dx.doi.org/10.1186/1471-2407-11-380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175225PMC
August 2011

Genotype-phenotype correlations in patients with retinoblastoma and interstitial 13q deletions.

Eur J Hum Genet 2011 Sep 20;19(9):947-58. Epub 2011 Apr 20.

Institut für Humangenetik, Universitätsklinikum Essen, Philipp-Rosenthal-Straße 55, Leipzig, Germany.

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http://dx.doi.org/10.1038/ejhg.2011.58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179359PMC
September 2011

Loss at chromosome arm 16q in retinoblastoma: confirmation of the association with diffuse vitreous seeding and refinement of the recurrently deleted region.

Genes Chromosomes Cancer 2011 May 8;50(5):327-37. Epub 2011 Feb 8.

Department of Neuroanatomy, Institute for Anatomy, University of Duisburg-Essen, Hufelandstrasse 55, Essen D-45122, Germany.

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http://dx.doi.org/10.1002/gcc.20857DOI Listing
May 2011

Clinical utility gene card for: retinoblastoma.

Eur J Hum Genet 2011 Mar 8;19(3). Epub 2010 Dec 8.

Klinische Forschergruppe Ophthalmologische Onkologie und Genetik, Institut für Humangenetik, Universität Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1038/ejhg.2010.200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061998PMC
March 2011

Retinoblastoma.

Authors:
Dietmar Lohmann

Adv Exp Med Biol 2010 ;685:220-7

Institut fur Humangenetik, Universitatsklinikum Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1007/978-1-4419-6448-9_21DOI Listing
August 2010

Imprinting of RB1 (the new kid on the block).

Brief Funct Genomics 2010 Jul 15;9(4):347-53. Epub 2010 Jun 15.

Institut für Humangenetik, D-45122 Essen, Germany.

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https://academic.oup.com/bfg/article-lookup/doi/10.1093/bfgp
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http://dx.doi.org/10.1093/bfgp/elq014DOI Listing
July 2010

The human retinoblastoma gene is imprinted.

PLoS Genet 2009 Dec 24;5(12):e1000790. Epub 2009 Dec 24.

Institut für Humangenetik, Universitätsklinikum Essen, Essen, Germany.

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http://dx.plos.org/10.1371/journal.pgen.1000790
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http://dx.doi.org/10.1371/journal.pgen.1000790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791201PMC
December 2009

Identification of a mutation in exon 27 of the RB1 gene associated with incomplete penetrance retinoblastoma.

Fam Cancer 2009 29;8(1):55-8. Epub 2008 May 29.

Institut für Humangenetik, Universitätsklinikum Essen, Hufelandstr. 55, Essen, 45122, Germany.

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http://dx.doi.org/10.1007/s10689-008-9198-4DOI Listing
April 2009

Patterns of missplicing caused by RB1 gene mutations in patients with retinoblastoma and association with phenotypic expression.

Hum Mutat 2008 Apr;29(4):475-84

Retinoblastoma Solutions, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/humu.20664DOI Listing
April 2008

Neurotrophin receptor expression in human primary retinoblastomas and retinoblastoma cell lines.

Pediatr Blood Cancer 2008 Feb;50(2):218-22

Department of Pediatric Hematology, Oncology and Endocrinology, University Hospital of Essen, Essen, Germany.

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http://dx.doi.org/10.1002/pbc.21369DOI Listing
February 2008

Allelic loss in a minimal region on chromosome 16q24 is associated with vitreous seeding of retinoblastoma.

Cancer Res 2007 Jan;67(1):408-16

Institut für Humangenetik, Institut für Zellbiologie, and Augenklinik, Universitätsklinikum Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-1317DOI Listing
January 2007

Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3.

Exp Eye Res 2006 Oct 5;83(4):858-64. Epub 2006 Jun 5.

Department of Ophthalmology, University of Duisburg-Essen, Augenklinik, Universitaetsklinikum Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1016/j.exer.2006.04.004DOI Listing
October 2006

Loss of heterozygosity of 1p in uveal melanomas with monosomy 3.

Int J Cancer 2005 Oct;116(6):909-13

Institut für Humangenetik, Universitätsklinikum Essen, Essen, Germany.

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http://doi.wiley.com/10.1002/ijc.21086
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http://dx.doi.org/10.1002/ijc.21086DOI Listing
October 2005

Detection of chromosomal imbalances in retinoblastoma by matrix-based comparative genomic hybridization.

Genes Chromosomes Cancer 2005 Jul;43(3):294-301

German Cancer Research Center, Division of Molecular Genetics, Heidelberg, Germany.

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http://doi.wiley.com/10.1002/gcc.20186
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http://dx.doi.org/10.1002/gcc.20186DOI Listing
July 2005

Retinoblastoma: revisiting the model prototype of inherited cancer.

Am J Med Genet C Semin Med Genet 2004 Aug;129C(1):23-8

Institut für Humangenetik, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://doi.wiley.com/10.1002/ajmg.c.30024
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http://dx.doi.org/10.1002/ajmg.c.30024DOI Listing
August 2004

Two brothers with Burn-McKeown syndrome.

Clin Dysmorphol 2003 Jul;12(3):171-4

Institut für Humangenetik, Universitätsklinikum Essen, Hufelandstr. 55, 45122 Essen, Germany.

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http://dx.doi.org/10.1097/01.mcd.0000072163.33788.c4DOI Listing
July 2003

A parent-of-origin effect in two families with retinoblastoma is associated with a distinct splice mutation in the RB1 gene.

Am J Hum Genet 2002 Jul 9;71(1):174-9. Epub 2002 May 9.

Institut für Humangenetik, Universitätsklinikum Essen, Germany.

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http://dx.doi.org/10.1086/341284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC384976PMC
July 2002