Dieter Schmoll

Dieter Schmoll

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Dieter Schmoll

Dieter Schmoll

Publications by authors named "Dieter Schmoll"

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Repletion of branched chain amino acids reverses mTORC1 signaling but not improved metabolism during dietary protein dilution.

Mol Metab 2017 08 24;6(8):873-881. Epub 2017 Jun 24.

Joint Research Division Molecular Metabolic Control, German Cancer Research Center, Center for Molecular Biology, Heidelberg University and Heidelberg University Hospital, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2017.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518726PMC
August 2017

The Keap1-Nrf2 protein-protein interaction: A suitable target for small molecules.

Drug Discov Today Technol 2017 Jun 31;24:11-17. Epub 2017 Oct 31.

Sanofi R&D, Industriepark Hoechst, D-65926 Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.ddtec.2017.10.001DOI Listing
June 2017

Inhibition of citrate cotransporter Slc13a5/mINDY by RNAi improves hepatic insulin sensitivity and prevents diet-induced non-alcoholic fatty liver disease in mice.

Mol Metab 2016 11 13;5(11):1072-1082. Epub 2016 Aug 13.

Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité - University School of Medicine, Berlin, 10117, Germany; DZHK (German Center for Cardiovascular Research), Partner Site, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2016.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081411PMC
November 2016

Pau d'arco activates Nrf2-dependent gene expression via the MEK/ERK-pathway.

J Toxicol Sci 2014 Apr;39(2):353-61

Sanofi-Aventis Deutschland, R&D, Industriepark Hoechst, Germany.

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http://dx.doi.org/10.2131/jts.39.353DOI Listing
April 2014

Identification and synthesis of novel inhibitors of acetyl-CoA carboxylase with in vitro and in vivo efficacy on fat oxidation.

J Med Chem 2010 Dec 17;53(24):8679-87. Epub 2010 Nov 17.

Sanofi-Aventis Deutschland GmbH, R&D, Diabetes Division, Industriepark Hoechst, Building G 878, D-65926 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1021/jm101179eDOI Listing
December 2010

Biophysical characterization of the interaction between hepatic glucokinase and its regulatory protein: impact of physiological and pharmacological effectors.

J Biol Chem 2008 Nov 22;283(46):31333-40. Epub 2008 Sep 22.

Sanofi Aventis Deutschland GmbH, Research and Development, D-65926 Frankfurt am Main, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M805434200
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http://dx.doi.org/10.1074/jbc.M805434200DOI Listing
November 2008

Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors.

Biochemistry 2008 Apr 29;47(16):4683-91. Epub 2008 Mar 29.

Research and Development, Sanofi Aventis Deutschland GmbH, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1021/bi702397dDOI Listing
April 2008

Dysregulated pyruvate dehydrogenase complex in Zucker diabetic fatty rats.

Am J Physiol Endocrinol Metab 2008 Jan 23;294(1):E88-96. Epub 2007 Oct 23.

Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, 65926 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1152/ajpendo.00178.2007DOI Listing
January 2008

CB1 receptor antagonist AVE1625 affects primarily metabolic parameters independently of reduced food intake in Wistar rats.

Am J Physiol Endocrinol Metab 2007 Sep 26;293(3):E826-32. Epub 2007 Jun 26.

Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, 65926 Frankfurt/Main, Germany.

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http://www.physiology.org/doi/10.1152/ajpendo.00264.2007
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http://dx.doi.org/10.1152/ajpendo.00264.2007DOI Listing
September 2007

Modulation of FoxO signaling in human hepatoma cells by exposure to copper or zinc ions.

Arch Biochem Biophys 2006 Oct 30;454(2):107-13. Epub 2006 Aug 30.

Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.abb.2006.08.016DOI Listing
October 2006

Endoplasmic reticulum stress increases glucose-6-phosphatase and glucose cycling in liver cells.

Endocrinology 2006 Jan 13;147(1):350-8. Epub 2005 Oct 13.

Departments of Food Science and Human Nutrition, Colorado State University, Fort Collins, Colorado 80523-1571, USA.

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http://dx.doi.org/10.1210/en.2005-1014DOI Listing
January 2006

The role of glucose 6-phosphate in mediating the effects of glucokinase overexpression on hepatic glucose metabolism.

FEBS J 2006 Jan;273(2):336-46

School of Clinical Medical Sciences-Diabetes, The University of Newcastle upon Tyne, Medical School, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1111/j.1742-4658.2005.05067.xDOI Listing
January 2006

Evidence for an indirect transcriptional regulation of glucose-6-phosphatase gene expression by liver X receptors.

Biochem Biophys Res Commun 2005 Dec 17;338(2):981-6. Epub 2005 Oct 17.

Department of Medical Biochemistry and Molecular Biology, University of Greifswald, D-17487 Greifswald, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2005.10.030DOI Listing
December 2005

FoxO proteins in insulin action and metabolism.

Trends Endocrinol Metab 2005 May-Jun;16(4):183-9

Department of Endocrinology, Diabetes and Rheumatology, University Hospital Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.tem.2005.03.010DOI Listing
July 2005

Characterization of cis-elements mediating the stimulation of glucose-6-phosphate transporter promoter activity by glucocorticoids.

Gene 2003 Nov;320:59-66

Department of Medical Biochemistry and Molecular Biology, University of Greifswald, Sauerbruchstr, D-17487 Greifswald, Germany.

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http://dx.doi.org/10.1016/s0378-1119(03)00810-2DOI Listing
November 2003

Novel concepts in insulin regulation of hepatic gluconeogenesis.

Am J Physiol Endocrinol Metab 2003 Oct;285(4):E685-92

Department of Endocrinology, Heinrich-Heine-University Düsseldorf, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1152/ajpendo.00253.2003DOI Listing
October 2003

DYRK1 is a co-activator of FKHR (FOXO1a)-dependent glucose-6-phosphatase gene expression.

Biochem Biophys Res Commun 2003 Jan;300(3):764-9

Institut für Pharmakologie und Toxikologie, Medizinische Fakultät der RWTH, D-52057 Aachen, Germany.

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http://dx.doi.org/10.1016/s0006-291x(02)02914-5DOI Listing
January 2003

Construction and characterization of a conditionally active construct of the insulin-regulated forkhead transcription factor FKHR.

Exp Clin Endocrinol Diabetes 2002 Sep;110(6):304-9

Institute of Pharmacology and Toxicology, Technical University of Aachen, Wendlingweg 2, D-52057 Aachen, Germany.

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http://dx.doi.org/10.1055/s-2002-34594DOI Listing
September 2002

Regulation of the forkhead transcription factor FKHR (FOXO1a) by glucose starvation and AICAR, an activator of AMP-activated protein kinase.

Endocrinology 2002 Aug;143(8):3183-6

Institut für Pharmakologie und Toxikologie, RWTH Aachen, D-52057 Aachen, Germany.

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http://dx.doi.org/10.1210/endo.143.8.8792DOI Listing
August 2002

Regulation of the Forkhead Transcription Factor FKHR (FOXO1a) by Glucose Starvation and AICAR, an Activator of AMP-Activated Protein Kinase.

Endocrinology 2002 Aug;143(8):3183-3186

German Institute of Human Nutrition, D-14558 Potsdam-Rehbrücke, Germany (H.-G.J.).

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http://dx.doi.org/10.1210/endo.143.8.8792DOI Listing
August 2002