Dieter P Reinhardt

Dieter P Reinhardt

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Dieter P Reinhardt

Publications by authors named "Dieter P Reinhardt"

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Biophysical Techniques to Analyze Elastic Tissue Extracellular Matrix Proteins Interacting with ADAMTS Proteins.

Methods Mol Biol 2020 ;2043:213-235

Faculty of Dentistry, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1007/978-1-4939-9698-8_18DOI Listing
January 2020

Quantification of Extracellular Matrix Fiber Systems Related to ADAMTS Proteins.

Methods Mol Biol 2020 ;2043:237-250

Faculty of Medicine, Department of Anatomy and Cell Biology, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1007/978-1-4939-9698-8_19DOI Listing
January 2020

Corrigendum to "The Fibrillin-1 RGD Integrin Binding Site Regulates Gene Expression and Cell Function Through microRNAs" [J. Mol. Biol. 431 (2) (2019) 401-421].

J Mol Biol 2020 Jan 6. Epub 2020 Jan 6.

Faculty of Medicine, McGill University, Montreal, Canada; Faculty of Dentistry, McGill University, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2019.12.022DOI Listing
January 2020

Fibulin-4 exerts a dual role in LTBP-4L-mediated matrix assembly and function.

Proc Natl Acad Sci U S A 2019 10 23;116(41):20428-20437. Epub 2019 Sep 23.

Faculty of Medicine, Department of Anatomy and Cell Biology, McGill University, Montreal, QC H3A 0C7, Canada;

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http://dx.doi.org/10.1073/pnas.1901048116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789559PMC
October 2019

Fibulin-4 deficiency differentially affects cytoskeleton structure and dynamics as well as TGFβ signaling.

Cell Signal 2019 06 4;58:65-78. Epub 2019 Mar 4.

Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Vascular Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Radiation Oncology, Erasmus University Medical Center, Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2019.02.008DOI Listing
June 2019

Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.

Matrix Biol 2019 04 7;77:117-128. Epub 2018 Sep 7.

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.09.004DOI Listing
April 2019

Increasing Cell Seeding Density Improves Elastin Expression and Mechanical Properties in Collagen Gel-Based Scaffolds Cellularized with Smooth Muscle Cells.

Biotechnol J 2019 Mar 17;14(3):e1700768. Epub 2018 Jun 17.

Laboratory for Biomaterials and Bioengineering, Canada Research Chair I in Biomaterials and Bioengineering for the Innovation in Surgery, Department of Min-Met-Materials Engineering, Research Center of CHU de Québec, Division of Regenerative Medicine, Laval University, Québec, QC G1V 0A6, Canada.

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http://dx.doi.org/10.1002/biot.201700768DOI Listing
March 2019

Lessons from tracheal tube development for understanding congenital tracheal malformations.

Eur Respir J 2019 Mar 7;53(3). Epub 2019 Mar 7.

Faculty of Medicine, Dept of Anatomy and Cell Biology, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1183/13993003.00127-2019DOI Listing
March 2019

The Fibrillin-1 RGD Integrin Binding Site Regulates Gene Expression and Cell Function through microRNAs.

J Mol Biol 2019 01 28;431(2):401-421. Epub 2018 Nov 28.

Faculty of Medicine, McGill University, Montreal, Canada; Faculty of Dentistry, McGill University, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2018.11.021DOI Listing
January 2019

Fibrillins.

Methods Cell Biol 2018 8;143:223-246. Epub 2017 Dec 8.

Faculty of Medicine and Faculty of Dentistry, McGill University, Montreal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/bs.mcb.2017.08.013DOI Listing
November 2018

Fibronectin promotes elastin deposition, elasticity and mechanical strength in cellularised collagen-based scaffolds.

Biomaterials 2018 10 12;180:130-142. Epub 2018 Jul 12.

Laboratory for Biomaterials and Bioengineering, Canada Research Chair I in Biomaterials and Bioengineering for the Innovation in Surgery, Department of Min-Met-Materials Engineering, Research Center of CHU de Quebec, Division of Regenerative Medicine, Laval University, Quebec City, QC G1V 0A6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2018.07.013DOI Listing
October 2018

Roles of fibronectin isoforms in neonatal vascular development and matrix integrity.

PLoS Biol 2018 07 23;16(7):e2004812. Epub 2018 Jul 23.

Faculty of Medicine, Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1371/journal.pbio.2004812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072322PMC
July 2018

Fibrillin-2 and Tenascin-C bridge the age gap in lung epithelial regeneration.

Biomaterials 2017 Sep 22;140:212-219. Epub 2017 Jun 22.

Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.1016/j.biomaterials.2017.06.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553709PMC
September 2017

Unusual life cycle and impact on microfibril assembly of ADAMTS17, a secreted metalloprotease mutated in genetic eye disease.

Sci Rep 2017 02 8;7:41871. Epub 2017 Feb 8.

Department of Biomedical Engineering, Cleveland Clinic Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, 44195, USA.

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http://www.nature.com/articles/srep41871
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http://dx.doi.org/10.1038/srep41871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296908PMC
February 2017

The Extracellular Matrix Signature in Vein Graft Disease.

Can J Cardiol 2016 08 1;32(8):1008.e11-7. Epub 2015 Dec 1.

Department of Dermatology, University of Lübeck, Lübeck, Germany; Institute of Virology and Cell Biology, University of Lübeck, Lübeck, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2015.11.014DOI Listing
August 2016

Soluble CD109 binds TGF-β and antagonizes TGF-β signalling and responses.

Biochem J 2016 Mar 30;473(5):537-47. Epub 2015 Nov 30.

Division of Plastic Surgery, Department of Surgery, McGill University Health Centre, Montreal, QC, Canada, H3G1A4

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http://dx.doi.org/10.1042/BJ20141488DOI Listing
March 2016

Fibronectin-targeted drug delivery in cancer.

Adv Drug Deliv Rev 2016 Feb 27;97:101-10. Epub 2015 Nov 27.

Faculty of Medicine, Department of Anatomy and Cell Biology, McGill University, Montreal, QC H3A 0C7, Canada; Faculty of Dentistry, McGill University, Montreal, QC H3A 0C7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2015.11.014DOI Listing
February 2016

Special issue: Extracellular matrix: Therapeutic tools and targets in cancer treatment.

Adv Drug Deliv Rev 2016 Feb;97:1-3

McGill University, Faculty of Medicine, Department of Anatomy and Cell Biology, and Faculty of Dentistry, Montreal, Canada.

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http://dx.doi.org/10.1016/j.addr.2016.01.001DOI Listing
February 2016

Fibrillin-containing microfibrils are key signal relay stations for cell function.

J Cell Commun Signal 2015 Dec 8;9(4):309-25. Epub 2015 Oct 8.

Faculty of Medicine, Department of Anatomy and Cell Biology, and Faculty of Dentistry, McGill University, 3640 University Street, Montreal, Quebec, H3A 0C7, Canada.

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http://dx.doi.org/10.1007/s12079-015-0307-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715827PMC
December 2015

Engineered mutations in fibrillin-1 leading to Marfan syndrome act at the protein, cellular and organismal levels.

Mutat Res Rev Mutat Res 2015 Jul-Sep;765:7-18. Epub 2015 May 5.

Faculty of Medicine, McGill University, Montreal, Canada; Faculty of Dentistry, McGill University, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.mrrev.2015.04.002DOI Listing
November 2015

Fibrillin-1 and alpha8 integrin are co-expressed in the glomerulus and interact to convey adhesion of mesangial cells.

Cell Adh Migr 2014 ;8(4):389-95

a Department for Pediatrics and Adolescent Medicine ; University Hospital of Erlangen ; Erlangen , Germany.

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http://dx.doi.org/10.4161/cam.28988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594580PMC
August 2015

Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia.

Dis Model Mech 2015 May 11;8(5):487-99. Epub 2015 Mar 11.

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA

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http://dx.doi.org/10.1242/dmm.017046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415891PMC
May 2015

Microfibril-associated disorders: fibrillinopathies.

J Glaucoma 2014 Oct-Nov;23(8 Suppl 1):S34-5

McGill University, Faculties of Medicine and Dentistry, Montreal, QC, Canada.

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http://dx.doi.org/10.1097/IJG.0000000000000114DOI Listing
April 2015

In vitro elastogenesis: instructing human vascular smooth muscle cells to generate an elastic fiber-containing extracellular matrix scaffold.

Biomed Mater 2015 Mar 18;10(3):034102. Epub 2015 Mar 18.

Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology (IGB), 70569 Stuttgart, Germany. Department of Women's Health, Research Institute for Women's Health, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1088/1748-6041/10/3/034102DOI Listing
March 2015

Human eye development is characterized by coordinated expression of fibrillin isoforms.

Invest Ophthalmol Vis Sci 2014 Nov 18;55(12):7934-44. Epub 2014 Nov 18.

Department of Biomedical Engineering, Cleveland Clinic, Lerner Research Institute, Cleveland, Ohio, United States.

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http://dx.doi.org/10.1167/iovs.14-15453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263138PMC
November 2014

Identification of molecular mechanisms used by Finegoldia magna to penetrate and colonize human skin.

Mol Microbiol 2014 Oct 11;94(2):403-17. Epub 2014 Sep 11.

Department of Clinical Sciences, Division of Infection Medicine, Lund University, SE-22184, Lund, Sweden.

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http://dx.doi.org/10.1111/mmi.12773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241043PMC
October 2014

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FEBS Lett 2014 Aug 14;588(17):2890-7. Epub 2014 Jul 14.

Faculty of Medicine, Department of Anatomy and Cell Biology, McGill University, Montreal, QC H3A 0C7, Canada; Faculty of Dentistry, McGill University, Montreal, QC H3A 0C7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2014.06.061DOI Listing
August 2014

Modulated growth, stability and interactions of liquid-like coacervate assemblies of elastin.

Matrix Biol 2014 Jun 12;36:39-50. Epub 2014 Apr 12.

Research Institute, Hospital for Sick Children, 555 University Ave, Toronto, Canada; Department of Biochemistry, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2014.03.008DOI Listing
June 2014

Early fibrillin-1 assembly monitored through a modifiable recombinant cell approach.

Biomacromolecules 2014 Apr 7;15(4):1456-68. Epub 2014 Mar 7.

Department of Anatomy and Cell Biology, Faculty of Medicine, McGill University , Montreal, Quebec H3A 0C7, Canada.

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http://dx.doi.org/10.1021/bm5000696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961472PMC
April 2014

Complex contributions of fibronectin to initiation and maturation of microfibrils.

Biochem J 2013 Dec;456(2):283-95

*Faculty of Medicine, Department of Anatomy and Cell Biology, McGill University, Montreal, QC, Canada, H3A 0C7.

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http://dx.doi.org/10.1042/BJ20130699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550319PMC
December 2013

Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.

Invest Ophthalmol Vis Sci 2013 Dec 23;54(13):8337-44. Epub 2013 Dec 23.

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

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http://dx.doi.org/10.1167/iovs.13-13121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875392PMC
December 2013

A new model of development of the mammalian ovary and follicles.

PLoS One 2013 7;8(2):e55578. Epub 2013 Feb 7.

Research Centre for Reproductive Health, Discipline of Obstetrics and Gynaecology, School of Paediatrics and Reproductive Health, Robinson Institute, University of Adelaide, SA, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055578PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567121PMC
September 2013

Fibrillin-1 directly regulates osteoclast formation and function by a dual mechanism.

J Cell Sci 2013 Sep;126(Pt 18):4187-94

Faculty of Dentistry, McGill University, 3640 rue University, Montreal, Quebec, Canada, H3A 0C7.

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http://dx.doi.org/10.1242/jcs.127571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961468PMC
September 2013

Fibulin-3, -4, and -5 are highly susceptible to proteolysis, interact with cells and heparin, and form multimers.

J Biol Chem 2013 Aug 19;288(31):22821-35. Epub 2013 Jun 19.

Faculty of Dentistry, Division of Biomedical Sciences, McGill University, Montreal, Quebec H3A 0C7, Canada.

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http://dx.doi.org/10.1074/jbc.M112.439158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829366PMC
August 2013

Elastogenesis at the onset of human cardiac valve development.

Development 2013 Jun 1;140(11):2345-53. Epub 2013 May 1.

University Women's Hospital Tübingen and Inter-University Centre for Medical Technology Stuttgart-Tübingen (IZST), Eberhard Karls University, 72076 Tübingen, Germany..

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http://dx.doi.org/10.1242/dev.093500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912871PMC
June 2013

Immobilized metal affinity chromatography co-purifies TGF-β1 with histidine-tagged recombinant extracellular proteins.

PLoS One 2012 31;7(10):e48629. Epub 2012 Oct 31.

Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048629PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485342PMC
May 2013

The evolution of extracellular fibrillins and their functional domains.

PLoS One 2012 16;7(3):e33560. Epub 2012 Mar 16.

Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0033560PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306419PMC
August 2012

Construction of a microstructured collagen membrane mimicking the papillary dermis architecture and guiding keratinocyte morphology and gene expression.

Macromol Biosci 2012 May 13;12(5):675-91. Epub 2012 Mar 13.

Department of Biochemistry 280, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/mabi.201100443DOI Listing
May 2012

Classical and neonatal Marfan syndrome mutations in fibrillin-1 cause differential protease susceptibilities and protein function.

J Biol Chem 2011 Sep 22;286(37):32810-23. Epub 2011 Jul 22.

Faculty of Dentistry, Division of Biomedical Sciences, Faculty of Medicine, McGill University, Montreal H3A 2B2, Canada.

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http://dx.doi.org/10.1074/jbc.M111.221804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173189PMC
September 2011

Linkage of regulators of TGF-β activity in the fetal ovary to polycystic ovary syndrome.

FASEB J 2011 Jul 16;25(7):2256-65. Epub 2011 Mar 16.

Research Centre for Reproductive Health, Discipline of Obstetrics and Gynaecology, Robinson Institute, University of Adelaide, SA, 5005, Australia.

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http://dx.doi.org/10.1096/fj.11-181099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219214PMC
July 2011

Homocysteine modifies structural and functional properties of fibronectin and interferes with the fibronectin-fibrillin-1 interaction.

Biochemistry 2011 Jun 19;50(23):5322-32. Epub 2011 May 19.

Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1021/bi200183zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112360PMC
June 2011

Fibrillin-3 expression in human development.

Matrix Biol 2011 Jan 21;30(1):43-52. Epub 2010 Oct 21.

Faculty of Medicine, Department of Anatomy and Cell Biology, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1016/j.matbio.2010.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961473PMC
January 2011

Lymphocytic infiltration leads to degradation of lacrimal gland extracellular matrix structures in NOD mice exhibiting a Sjögren's syndrome-like exocrinopathy.

Exp Eye Res 2010 Feb 21;90(2):223-37. Epub 2009 Oct 21.

Department of Medicine/Cardiology, Cardiovascular Research Laboratories, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1760, USA.

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http://dx.doi.org/10.1016/j.exer.2009.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821966PMC
February 2010

Functional consequences of homocysteinylation of the elastic fiber proteins fibrillin-1 and tropoelastin.

J Biol Chem 2010 Jan 4;285(2):1188-98. Epub 2009 Nov 4.

Faculty of Medicine, Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec H3A 2B2, Canada.

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http://dx.doi.org/10.1074/jbc.M109.021246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801247PMC
January 2010

Microscale mechanical properties of single elastic fibers: the role of fibrillin-microfibrils.

Biomaterials 2009 May 13;30(13):2425-32. Epub 2009 Feb 13.

Department of Biochemistry, Nijmegen Center for Molecular Life Sciences, University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.biomaterials.2009.01.038DOI Listing
May 2009

One more piece in the fibrillin puzzle.

Structure 2009 May;17(5):635-6

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http://dx.doi.org/10.1016/j.str.2009.04.002DOI Listing
May 2009

Fibrillin assembly requires fibronectin.

Mol Biol Cell 2009 Feb 26;20(3):846-58. Epub 2008 Nov 26.

Faculty of Medicine, Department of Anatomy and Cell Biology, McGill University, Montreal, QC, Canada H3A 2B2.

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http://dx.doi.org/10.1091/mbc.e08-08-0830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633374PMC
February 2009

Role for ephrinB2 in postnatal lung alveolar development and elastic matrix integrity.

Dev Dyn 2008 Aug;237(8):2220-34

Department of Molecular Neurobiology, Max-Planck Institute of Neurobiology, Munich-Martinsried, Germany.

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http://doi.wiley.com/10.1002/dvdy.21643
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http://dx.doi.org/10.1002/dvdy.21643DOI Listing
August 2008

Biogenesis of extracellular microfibrils: Multimerization of the fibrillin-1 C terminus into bead-like structures enables self-assembly.

Proc Natl Acad Sci U S A 2008 May 30;105(18):6548-53. Epub 2008 Apr 30.

Faculty of Medicine, Department of Anatomy and Cell Biology and Faculty of Dentistry, Division of Biomedical Sciences, McGill University, Montreal, QC, Canada.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0706335105
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http://dx.doi.org/10.1073/pnas.0706335105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373353PMC
May 2008

A biomaterial composed of collagen and solubilized elastin enhances angiogenesis and elastic fiber formation without calcification.

Tissue Eng Part A 2008 Mar;14(3):349-60

Department of Biochemistry 280, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1089/tea.2007.0076DOI Listing
March 2008

Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.

J Biol Chem 2007 Mar 25;282(12):8935-46. Epub 2007 Jan 25.

Faculty of Medicine, Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec H3A 2B2, Canada.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M608204200
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http://dx.doi.org/10.1074/jbc.M608204200DOI Listing
March 2007

Functional diversity of lysyl hydroxylase 2 in collagen synthesis of human dermal fibroblasts.

Exp Cell Res 2006 Nov 28;312(18):3485-94. Epub 2006 Jul 28.

Department of Dermatology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S001448270600295
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http://dx.doi.org/10.1016/j.yexcr.2006.07.013DOI Listing
November 2006

Fibrillins: from biogenesis of microfibrils to signaling functions.

Curr Top Dev Biol 2006 ;75:93-123

Department of Anatomy and Cell Biology, Faculty of Medicine, McGill University Montreal, Quebec, H3A 2B2, Canada.

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http://dx.doi.org/10.1016/S0070-2153(06)75004-9DOI Listing
October 2006

Role of fibrillin-1 in hypertensive and diabetic glomerular disease.

Am J Physiol Renal Physiol 2006 Jun 27;290(6):F1329-36. Epub 2005 Dec 27.

Hospital for Children and Adolescents, University of Erlangen-Nurnberg, Erlangen, Germany.

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http://dx.doi.org/10.1152/ajprenal.00284.2005DOI Listing
June 2006

Characterization of a conduit system containing laminin-5 in the human thymus: a potential transport system for small molecules.

J Cell Sci 2006 Apr 14;119(Pt 7):1396-405. Epub 2006 Mar 14.

Section for Transplantation Immunology and Immunohematology, Center for Medical Research, University of Tübingen, 72072 Tübingen, Germany.

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http://dx.doi.org/10.1242/jcs.02840DOI Listing
April 2006

Modification of the structure and function of fibrillin-1 by homocysteine suggests a potential pathogenetic mechanism in homocystinuria.

J Biol Chem 2005 Oct 11;280(41):34946-55. Epub 2005 Aug 11.

Faculty of Medicine, Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec H3A2B2, Canada.

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http://dx.doi.org/10.1074/jbc.M504748200DOI Listing
October 2005

Enhanced expression of fibrillin-1, a constituent of the myocardial extracellular matrix in fibrosis.

Am J Physiol Heart Circ Physiol 2005 Sep 22;289(3):H982-91. Epub 2005 Apr 22.

Institut de Recherches Cliniques de Montréal, Montréal, Québec, Canada H2W 1R7.

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http://dx.doi.org/10.1152/ajpheart.00151.2005DOI Listing
September 2005

Microfibrils at basement membrane zones interact with perlecan via fibrillin-1.

J Biol Chem 2005 Mar 17;280(12):11404-12. Epub 2005 Jan 17.

Department of Medical Molecular Biology, University of Lübeck, 23538 Lübeck, Germany.

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http://dx.doi.org/10.1074/jbc.M409882200DOI Listing
March 2005

RGD-containing fibrillin-1 fragments upregulate matrix metalloproteinase expression in cell culture: a potential factor in the pathogenesis of the Marfan syndrome.

Hum Genet 2005 Jan 23;116(1-2):51-61. Epub 2004 Oct 23.

Institute of Medical Genetics, Charité University Hospital, Humboldt University Berlin, Augustenburger Platz 1, Berlin 13353, Germany.

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http://link.springer.com/10.1007/s00439-004-1194-7
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http://dx.doi.org/10.1007/s00439-004-1194-7DOI Listing
January 2005

Characterization of the renal phenotype in a mouse model of Marfan syndrome.

Virchows Arch 2004 Oct 29;445(4):382-8. Epub 2004 Jul 29.

Department of Pediatrics, University of Erlangen-Nürnberg, Loschgestrasse 15, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1007/s00428-004-1081-6DOI Listing
October 2004

Consequences of cysteine mutations in calcium-binding epidermal growth factor modules of fibrillin-1.

J Biol Chem 2004 Jul 25;279(31):32924-31. Epub 2004 May 25.

Department of Medical Molecular Biology of the University of Lübeck, D-23538 Luebeck, Germany.

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http://dx.doi.org/10.1074/jbc.M405239200DOI Listing
July 2004

Molecular structure and interaction of recombinant human type XVI collagen.

J Mol Biol 2004 Jun;339(4):835-53

Institut für Physiologische Chemie und Pathobiochemie, Universitätsklinikum Münster, Waldeyerstr. 15, 48149 Münster, Germany.

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http://dx.doi.org/10.1016/j.jmb.2004.03.042DOI Listing
June 2004

Fibrillin-1 expression in normal and fibrotic rat liver and in cultured hepatic fibroblastic cells: modulation by mechanical stress and role in cell adhesion.

Lab Invest 2004 Feb;84(2):203-12

Groupe de Recherches pour l'Etude du Foie, INSERM E0362, and Institut Fédératif de Recherche 66, Pathologies Infectieuses et Cancers, Université Victor Segalen Bordeaux 2, Bordeaux, France.

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http://dx.doi.org/10.1038/labinvest.3700023DOI Listing
February 2004

Discrete integration of collagen XVI into tissue-specific collagen fibrils or beaded microfibrils.

Matrix Biol 2003 Apr;22(2):131-43

Institut für Physiologische Chemie und Pathobiochemie, Universitätsklinikum Münster, Waldeyerstrasse 15, 48129 Münster, Germany.

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http://dx.doi.org/10.1016/s0945-053x(03)00008-8DOI Listing
April 2003

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

J Biol Chem 2003 Jan 11;278(4):2750-7. Epub 2002 Nov 11.

Department of Biochemistry and Molecular Biology, Shriners Hospital for Children, Oregon Health and Science University, Portland 97239, USA.

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http://dx.doi.org/10.1074/jbc.M209256200DOI Listing
January 2003

Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.

J Biol Chem 2003 Jan 11;278(4):2740-9. Epub 2002 Nov 11.

Department of Biochemistry and Molecular Biology, Shriners Hospital for Children, Oregon Health and Science University, Portland 97201, USA.

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http://dx.doi.org/10.1074/jbc.M209201200DOI Listing
January 2003

Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.

J Biol Chem 2002 Dec 23;277(52):50795-804. Epub 2002 Oct 23.

Department of Medical Molecular Biology, University of Lübeck, Germany.

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http://dx.doi.org/10.1074/jbc.M210611200DOI Listing
December 2002

Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.

Matrix Biol 2002 Dec;21(8):637-46

Department of Histology, University of Göttingen, Kreuzbergring 36, Germany.

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http://dx.doi.org/10.1016/s0945-053x(02)00100-2DOI Listing
December 2002

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

Biochem J 2002 Nov;367(Pt 3):715-21

Institute for Biochemistry, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 52, D-50931 Cologne, Germany.

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http://dx.doi.org/10.1042/BJ20021069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222949PMC
November 2002

Versican interacts with fibrillin-1 and links extracellular microfibrils to other connective tissue networks.

J Biol Chem 2002 Feb 28;277(6):4565-72. Epub 2001 Nov 28.

Shriners Hospital for Children and the Department of Biochemistry and Molecular Biology, Oregon Health Sciences University, Portland, Oregon 97201, USA.

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http://dx.doi.org/10.1074/jbc.M110583200DOI Listing
February 2002