Dieter E Jenne

Dieter E Jenne

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Dieter E Jenne

Dieter E Jenne

Publications by authors named "Dieter E Jenne"

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Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation.

Sci Rep 2019 Jul 9;9(1):9925. Epub 2019 Jul 9.

Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease (iLBD), Helmholtz Zentrum München and University Hospital of the Ludwig-Maximilians University (LMU), Munich, 81377, Germany.

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http://dx.doi.org/10.1038/s41598-019-46206-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616352PMC
July 2019

Preservation with α-antitrypsin improves primary graft function of murine lung transplants.

J Heart Lung Transplant 2018 08 30;37(8):1021-1028. Epub 2018 Mar 30.

Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München and University Hospital of the Ludwig-Maximilians University, Munich, Germany; German Center for Lung Research, Munich, Germany; Max Planck Institute of Neurobiology, Planegg-Martinsried, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10532498183142
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http://dx.doi.org/10.1016/j.healun.2018.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078707PMC
August 2018

Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases.

Biochem Pharmacol 2017 05 11;131:52-67. Epub 2017 Feb 11.

INSERM U-1100, "Centre d'Etude des Pathologies Respiratoires" and Université François Rabelais, Tours, France; Department of Pathology, University of Washington, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.02.009DOI Listing
May 2017

Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease.

Pharmacol Rev 2016 07;68(3):603-30

INSERM U-1100, Centre d'Etude des Pathologies Respiratoires and Université François Rabelais, Tours, France (B.K., C.G., F.G.); Faculty of Chemistry, University of Gdansk, Gdansk, Poland (A.L., M.W.); Architecture et Fonction des Macromolécules Biologiques, Unité Mixte de Recherche 7257, Marseille, France (C.K.); Génétique, Immunothérapie, Chimie et Cancer, Unité Mixte de Recherche 7292, Université François Rabelais, Tours, France (H.W.); Thoracic Diseases Research Unit, Division of Pulmonary and Critical Care Medicine, Mayo Clinic and Foundation, Rochester, Minnesota (U.S.); Comprehensive Pneumology Center, Institute of Lung Biology and Disease, German Center for Lung Research, Munich, Germany (D.E.J.); and Max Planck Institute of Neurobiology, Planegg-Martinsried, Germany (D.E.J.).

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http://dx.doi.org/10.1124/pr.115.012104DOI Listing
July 2016

Allosteric modulation of proteinase 3 activity by anti-neutrophil cytoplasmic antibodies in granulomatosis with polyangiitis.

J Autoimmun 2015 May 3;59:43-52. Epub 2015 Mar 3.

Comprehensive Pneumology Center, Institute of Lung Biology and Disease (iLBD), University Hospital, Ludwig Maximilians University and Helmholtz Zentrum München, Member of the German Center of Lung Research, Max-Lebsche-Platz 31, 81377 Munich, Germany; Max Planck Institute of Neurobiology, Planegg-Martinsried, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2015.02.002DOI Listing
May 2015

Off-target rewards of augmentation therapy with α1-antitrypsin.

Authors:
Dieter E Jenne

Am J Respir Crit Care Med 2014 Dec;190(11):1203-4

1 Comprehensive Pneumology Center Helmholtz Zentrum München Munich, Germany and.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.201410-1809E
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http://dx.doi.org/10.1164/rccm.201410-1809EDDOI Listing
December 2014

Unopposed cathepsin G, neutrophil elastase, and proteinase 3 cause severe lung damage and emphysema.

Am J Pathol 2014 Aug 12;184(8):2197-210. Epub 2014 Jun 12.

Inflammation and Immunity of the Respiratory Epithelium Group, EA-4303, Reims, Inserm U-1111, Lyon-Sud, France. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.04.015DOI Listing
August 2014

Relevance of the mouse model as a therapeutic approach for neutrophil proteinase 3-associated human diseases.

Int Immunopharmacol 2013 Dec 23;17(4):1198-205. Epub 2013 Jul 23.

"Centre d'Etudes des Pathologies Respiratoires", INSERM U-1100/EA-6305 37032, Université François Rabelais, 37032 Tours, France. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2013.07.003DOI Listing
December 2013

A monoclonal antibody (MCPR3-7) interfering with the activity of proteinase 3 by an allosteric mechanism.

J Biol Chem 2013 Sep 31;288(37):26635-48. Epub 2013 Jul 31.

From the Comprehensive Pneumology Center, Institute of Lung Biology and Disease (iLBD), University Hospital, Ludwig Maximilians University and Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Max-Lebsche-Platz 31, 81377 Munich, Germany.

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http://dx.doi.org/10.1074/jbc.M113.495770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772210PMC
September 2013

NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity.

J Immunol 2013 Sep 31;191(5):2700-7. Epub 2013 Jul 31.

Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München, Member of the German Center for Lung Research, 81377 Munich, Germany.

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http://dx.doi.org/10.4049/jimmunol.1301293DOI Listing
September 2013

Perspectives and potential roles for the newly discovered NSP4 in the immune system.

Expert Rev Clin Immunol 2012 Aug;8(6):501-3

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http://dx.doi.org/10.1586/eci.12.39DOI Listing
August 2012

NSP4, an elastase-related protease in human neutrophils with arginine specificity.

Proc Natl Acad Sci U S A 2012 Apr 2;109(16):6229-34. Epub 2012 Apr 2.

Department of Neuroimmunology, Max Planck Institute of Neurobiology, 82152 Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1073/pnas.1200470109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341072PMC
April 2012

Tailor-made inflammation: how neutrophil serine proteases modulate the inflammatory response.

J Mol Med (Berl) 2011 Jan 31;89(1):23-8. Epub 2010 Aug 31.

Department of Anatomy, University of California, 513 Parnassus Avenue, San Francisco, CA 94143-0452, USA.

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http://dx.doi.org/10.1007/s00109-010-0677-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016231PMC
January 2011

Neutrophils require SHP1 to regulate IL-1β production and prevent inflammatory skin disease.

J Immunol 2011 Jan 15;186(2):1131-9. Epub 2010 Dec 15.

Cancer and Haematology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1002702
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http://dx.doi.org/10.4049/jimmunol.1002702DOI Listing
January 2011

Discrimination and variable impact of ANCA binding to different surface epitopes on proteinase 3, the Wegener's autoantigen.

J Autoimmun 2010 Dec;35(4):299-308

Thoracic Diseases Research Unit, Stabile Bldg. 8-56, Division of Pulmonary and Critical Care Medicine, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.jaut.2010.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963671PMC
December 2010

Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.

Pharmacol Rev 2010 Dec;62(4):726-59

INSERM U-618 Protéases et Vectorisation Pulmonaires, Université François Rabelais, Faculté de médecine, 10 Boulevard Tonnellé, Tours, France.

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http://pharmrev.aspetjournals.org/cgi/doi/10.1124/pr.110.002
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http://dx.doi.org/10.1124/pr.110.002733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993259PMC
December 2010

Mapping of conformational epitopes on human proteinase 3, the autoantigen of Wegener's granulomatosis.

J Immunol 2010 Jul 7;185(1):387-99. Epub 2010 Jun 7.

Department of Neuroimmunology, Max-Planck-Institute of Neurobiology, Planegg/Martinsried, Germany.

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http://dx.doi.org/10.4049/jimmunol.0903887DOI Listing
July 2010

Delivery and therapeutic potential of human granzyme B.

Immunol Rev 2010 May;235(1):159-71

Institute of Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1111/j.0105-2896.2010.00894.xDOI Listing
May 2010

Gold fluorescent annexin A5 as a novel apoptosis detection tool.

Cytometry A 2009 Jul;75(7):626-33

Max Planck Institute of Neurobiology, Department of Neuroimmunology, Martinsried, Germany.

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http://dx.doi.org/10.1002/cyto.a.20737DOI Listing
July 2009

A hydrophobic patch on proteinase 3, the target of autoantibodies in Wegener granulomatosis, mediates membrane binding via NB1 receptors.

J Biol Chem 2008 Dec 14;283(51):35976-82. Epub 2008 Oct 14.

Department of Neuroimmunology, Max-Planck-Institute of Neurobiology, D-82152 Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1074/jbc.M806754200DOI Listing
December 2008

Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis.

Proc Natl Acad Sci U S A 2008 Sep 4;105(37):13799-804. Epub 2008 Sep 4.

Department of Neuroimmunology, Max Planck Institute of Neurobiology, Am Klopferspitz 18, D-82152 Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1073/pnas.0801724105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2544534PMC
September 2008

Myofibrillar myopathy with arrhythmogenic right ventricular cardiomyopathy 7: corroboration and narrowing of the critical region on 10q22.3.

Eur J Hum Genet 2008 Mar 16;16(3):367-73. Epub 2008 Jan 16.

Department of Neuroimmunology, Max-Planck-Institute of Neurobiology, Martinsried, Germany.

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http://dx.doi.org/10.1038/sj.ejhg.5201980DOI Listing
March 2008

Natural killer cell-derived human granzyme H induces an alternative, caspase-independent cell-death program.

Blood 2007 Jul 4;110(2):544-52. Epub 2007 Apr 4.

Department of Neuroimmunology, Max-Planck-Institut of Neurobiology, Martinsried, Germany.

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http://dx.doi.org/10.1182/blood-2006-10-051649DOI Listing
July 2007

Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition.

EMBO J 2007 Apr 15;26(8):2148-57. Epub 2007 Mar 15.

Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, Mexico.

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http://dx.doi.org/10.1038/sj.emboj.7601650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852776PMC
April 2007

Differential expression of the granzymes A, K and M and perforin in human peripheral blood lymphocytes.

Int Immunol 2005 Nov 26;17(11):1419-28. Epub 2005 Sep 26.

Department of Pneumology, University Medical Clinic Rostock, Schillingallee 35, D-18057 Rostock, Germany.

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http://dx.doi.org/10.1093/intimm/dxh320DOI Listing
November 2005

Differences between human proteinase 3 and neutrophil elastase and their murine homologues are relevant for murine model experiments.

FEBS Lett 2005 Oct;579(24):5305-12

Thoracic Diseases Research Unit, Division of Pulmonary and Critical Care Medicine, Mayo Clinic Foundation, Rochester, MN 55905, USA.

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http://doi.wiley.com/10.1016/j.febslet.2005.08.056
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http://dx.doi.org/10.1016/j.febslet.2005.08.056DOI Listing
October 2005

Membrane receptors are not required to deliver granzyme B during killer cell attack.

Blood 2005 Mar 4;105(5):2049-58. Epub 2004 Nov 4.

Department of Neuroimmunology, Max-Planck-Institute of Neurobiology, Am Klopferspitz 18, D-82152 Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1182/blood-2004-06-2180DOI Listing
March 2005

Antineutrophil cytoplasmic autoantibodies against the murine homolog of proteinase 3 (Wegener autoantigen) are pathogenic in vivo.

Blood 2004 Sep 18;104(5):1411-8. Epub 2004 May 18.

Department of Neuroimmunology, Max-Planck Institute of Neurobiology, Am Klopferspitz 18A, D-82152 Martinsried, Germany.

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http://dx.doi.org/10.1182/blood-2004-01-0267DOI Listing
September 2004

Killing of target cells by redirected granzyme B in the absence of perforin.

FEBS Lett 2004 Mar;562(1-3):87-92

Department of Neuroimmunology, Max-Planck-Institute of Neurobiology, Am Klopferspitz 18A, D-82152 Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1016/S0014-5793(04)00187-5DOI Listing
March 2004

Crystal structure of the apoptosis-inducing human granzyme A dimer.

Nat Struct Biol 2003 Jul;10(7):535-40

Department of Neuroimmunology, Max Planck Institute of Neurobiology, Am Klopferspitz 18a, D-82152 Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1038/nsb945DOI Listing
July 2003

Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse.

Genes Chromosomes Cancer 2003 Jun;37(2):111-20

Department of Neuroimmunology, Max-Planck-Institute of Neurobiology, Martinsried, Germany.

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http://dx.doi.org/10.1002/gcc.10206DOI Listing
June 2003

The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features.

J Biol Chem 2002 Dec 15;277(52):50923-33. Epub 2002 Oct 15.

Department of Neuroimmunology, Max-Planck-Institute of Neurobiology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18a, Planegg-Martinsried D-82152, Germany.

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http://dx.doi.org/10.1074/jbc.M207962200DOI Listing
December 2002

Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis.

Proc Natl Acad Sci U S A 2002 Jun 11;99(13):8903-8. Epub 2002 Jun 11.

Pharmaceutical Technology Laboratory, Chugai Pharmaceutical Co., Ltd., 1-135 Komakado, Gotemba, Shizuoka 412-8513, Japan.

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http://dx.doi.org/10.1073/pnas.122254599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC124396PMC
June 2002