Diego Haro

Diego Haro

UNVERIFIED PROFILE

Are you Diego Haro?   Register this Author

Register author
Diego Haro

Diego Haro

Publications by authors named "Diego Haro"

Are you Diego Haro?   Register this Author

32Publications

298Reads

5Profile Views

Lyophilized Maqui () Berry Induces Browning in the Subcutaneous White Adipose Tissue and Ameliorates the Insulin Resistance in High Fat Diet-Induced Obese Mice.

Antioxidants (Basel) 2019 Sep 1;8(9). Epub 2019 Sep 1.

Department of Nutrition, Food Sciences and Gastronomy, School of Pharmacy and Food Sciences, Food Torribera Campus, University of Barcelona, E-08921 Santa Coloma de Gramenet, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/antiox8090360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769892PMC
September 2019

Fibroblast Growth Factor 21 and the Adaptive Response to Nutritional Challenges.

Int J Mol Sci 2019 Sep 21;20(19). Epub 2019 Sep 21.

Department of Nutrition, Food Sciences and Gastronomy, School of Pharmacy and Food Sciences, Food Torribera Campus, University of Barcelona, E-08921 Santa Coloma de Gramenet, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20194692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801670PMC
September 2019

Nutritional Regulation of Gene Expression: Carbohydrate-, Fat- and Amino Acid-Dependent Modulation of Transcriptional Activity.

Int J Mol Sci 2019 Mar 19;20(6). Epub 2019 Mar 19.

Department of Nutrition, Food Sciences and Gastronomy, School of Pharmacy and Food Sciences, Food Campus Torribera, University of Barcelona, E-08921 Santa Coloma de Gramenet, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20061386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470599PMC
March 2019

Mediterranean Tomato-Based Sofrito Sauce Improves Fibroblast Growth Factor 21 (FGF21) Signaling in White Adipose Tissue of Obese ZUCKER Rats.

Mol Nutr Food Res 2018 02 30;62(4). Epub 2018 Jan 30.

Department of Nutrition, Food Sciences and Gastronomy, School of Pharmacy and Food Sciences, Food and Nutrition Torribera Campus, University of Barcelona, Santa Coloma de Gramenet, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mnfr.201700606DOI Listing
February 2018

A low-protein diet induces body weight loss and browning of subcutaneous white adipose tissue through enhanced expression of hepatic fibroblast growth factor 21 (FGF21).

Mol Nutr Food Res 2017 08 2;61(8). Epub 2017 Mar 2.

Department of Nutrition, Food Sciences and Gastronomy, School of Pharmacy and Food Science, University of Barcelona, Torribera Food Campus, Santa Coloma de Gramenet, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mnfr.201600725DOI Listing
August 2017

Regulation of human class I alcohol dehydrogenases by bile acids.

J Lipid Res 2013 Sep 16;54(9):2475-84. Epub 2013 Jun 16.

Department of Biochemistry and Molecular Biology, School of Pharmacy and Institute of Biomedicine of University of Barcelona, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M039404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735944PMC
September 2013

FGF21 mediates the lipid metabolism response to amino acid starvation.

J Lipid Res 2013 Jul 9;54(7):1786-97. Epub 2013 May 9.

Departament de Bioquímica i Biologia Molecular, Facultat de Farmàcia, Universitat de Barcelona, 08028 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M033415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679382PMC
July 2013

Regulation of N-Myc downstream regulated gene 2 by bile acids.

Biochem Biophys Res Commun 2013 Apr 27;434(1):102-9. Epub 2013 Mar 27.

Department of Biochemistry and Molecular Biology, Faculty of Pharmacy and the Institute of Biomedicine of the University of Barcelona, Barcelona E-08028, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2013.03.058DOI Listing
April 2013

Fsp27/CIDEC is a CREB target gene induced during early fasting in liver and regulated by FA oxidation rate.

J Lipid Res 2013 Mar 6;54(3):592-601. Epub 2012 Dec 6.

Department of Biochemistry and Molecular Biology, School of Pharmacy and the Institute of Biomedicine of the University of Barcelona, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M028472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617935PMC
March 2013

PGC-1β regulates mouse carnitine-acylcarnitine translocase through estrogen-related receptor α.

Biochem Biophys Res Commun 2012 Jul 16;423(4):838-43. Epub 2012 Jun 16.

Department of Biochemistry and Molecular Biology, School of Pharmacy and the Institute of Biomedicine of the University of Barcelona, Spain.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S0006291X1201139
Publisher Site
http://dx.doi.org/10.1016/j.bbrc.2012.06.051DOI Listing
July 2012

Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer.

BMC Cancer 2012 Jul 6;12:280. Epub 2012 Jul 6.

Molecular Oncology (NEOMA), School of Medicine, University of Girona and Girona Institute for Biomedical Research (IDIBGi), 17071, Girona, Spain.

View Article

Download full-text PDF

Source
http://bmccancer.biomedcentral.com/articles/10.1186/1471-240
Publisher Site
http://dx.doi.org/10.1186/1471-2407-12-280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500220PMC
July 2012

New synthetic inhibitors of fatty acid synthase with anticancer activity.

J Med Chem 2012 Jun 16;55(11):5013-23. Epub 2012 May 16.

Departamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, E-28040 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jm2016045DOI Listing
June 2012

Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation.

Biochem J 2012 Apr;443(1):165-71

Department of Biochemistry and Molecular Biology, School of Pharmacy and the Institute of Biomedicine of the University of Barcelona (IBUB), Av. Joan XXIII s/n, E-08028 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20111748DOI Listing
April 2012

Human HMGCS2 regulates mitochondrial fatty acid oxidation and FGF21 expression in HepG2 cell line.

J Biol Chem 2011 Jun 18;286(23):20423-30. Epub 2011 Apr 18.

Department of Biochemistry and Molecular Biology, School of Pharmacy and the Institute of Biomedicine of the University of Barcelona, E-08028 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M111.235044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121469PMC
June 2011

Transcriptional regulation of the human acetoacetyl-CoA synthetase gene by PPARgamma.

Biochem J 2010 Mar 29;427(2):255-64. Epub 2010 Mar 29.

Department of Biochemistry and Molecular Biology, Institute of Biomedicine of Barcelona University, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20090851DOI Listing
March 2010

Novel Inhibitors of Fatty Acid Synthase with Anticancer Activity.

Clin Cancer Res 2009 Dec;15(24):7608-7615

Authors' Affiliations: Institut Català d'Oncologia and Institut d'Investigació Biomèdica de Girona, Bioquímica i Biologia Molecular, Facultat de Ciències, Universitat de Girona, Girona, Spain; Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, M.D. Anderson Cancer Center España, Madrid, Spain; Institut Català d'Oncologia and Institut d'Investigació Biomèdica de Bellvitge, and Bioquímica i Biologia Molecular, Institut de Biomedicina, Universitat de Barcelona, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-09-0856DOI Listing
December 2009

Green tea catechin inhibits fatty acid synthase without stimulating carnitine palmitoyltransferase-1 or inducing weight loss in experimental animals.

Anticancer Res 2008 Nov-Dec;28(6A):3671-6

Girona Biomedical Research Institute (IdIBGi) and Catalan Institute of Oncology, Dr. Josep Trueta University Hospital, Girona, Spain.

View Article

Download full-text PDF

Source
March 2009

A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme.

FEBS J 2009 Jan 22;276(1):210-8. Epub 2008 Nov 22.

Department of Biochemistry and Molecular Biology, School of Pharmacy and Institute of Biomedicine of Barcelona University (IBUB), Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1742-4658.2008.06774.xDOI Listing
January 2009

Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75.

Breast Cancer Res Treat 2008 Jun 28;109(3):471-9. Epub 2007 Sep 28.

Fundació d'Investigació Biomèdica de Girona Dr. Josep Trueta (IdIBGi), Hospital Universitari de Girona Dr. Josep Trueta, Girona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-007-9678-5DOI Listing
June 2008

Ketogenic HMGCS2 Is a c-Myc target gene expressed in differentiated cells of human colonic epithelium and down-regulated in colon cancer.

Mol Cancer Res 2006 Sep 28;4(9):645-53. Epub 2006 Aug 28.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, E-08028 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-05-0267DOI Listing
September 2006

An intronic peroxisome proliferator-activated receptor-binding sequence mediates fatty acid induction of the human carnitine palmitoyltransferase 1A.

J Mol Biol 2005 Dec 21;354(4):751-9. Epub 2005 Oct 21.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, 08028 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmb.2005.09.097DOI Listing
December 2005

C75 activates malonyl-CoA sensitive and insensitive components of the CPT system.

Biochem Biophys Res Commun 2004 Dec;325(3):660-4

Department of Biochemistry and Molecular Biology, School of Pharmacy University of Barcelona, E-08028 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2004.10.085DOI Listing
December 2004

Pig muscle carnitine palmitoyltransferase I (CPTI beta), with low Km for carnitine and low sensitivity to malonyl-CoA inhibition, has kinetic characteristics similar to those of the rat liver (CPTI alpha) enzyme.

Biochemistry 2004 Oct;43(39):12686-91

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, 08028 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi0488597DOI Listing
October 2004

Functional interaction between peroxisome proliferator-activated receptors-alpha and Mef-2C on human carnitine palmitoyltransferase 1beta (CPT1beta) gene activation.

Nucleic Acids Res 2004 8;32(16):4742-9. Epub 2004 Sep 8.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Avenue Diagonal 643, E-08028 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkh806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC519104PMC
September 2004

Influence of DMBA-induced mammary cancer on the liver CPT I, mit HMG-CoA synthase and PPARalpha mRNA expression in rats fed a low or high corn oil diet.

Int J Mol Med 2004 Aug;14(2):283-7

Department of Cell Biology, Physiology and Immunology, Medical Physiology Unit, School of Medicine, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain.

View Article

Download full-text PDF

Source
August 2004

Chicken ovalbumin upstream promoter-transcription factor I represses the transcriptional activity of the human muscle glycogen phosphorylase promoter in C2C12 cells.

Biochim Biophys Acta 2004 May;1678(2-3):157-62

Department de Bioquímica i Biologia Molecular, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1, E-08028 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbaexp.2004.02.003DOI Listing
May 2004

A single amino acid change (substitution of the conserved Glu-590 with alanine) in the C-terminal domain of rat liver carnitine palmitoyltransferase I increases its malonyl-CoA sensitivity close to that observed with the muscle isoform of the enzyme.

J Biol Chem 2003 Sep 25;278(36):34084-9. Epub 2003 Jun 25.

Department of Environmental and Biomolecular Systems, OGI School of Science & Engineering, Oregon Health & Science University, Beaverton, Oregon 97006-8921, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M305826200DOI Listing
September 2003

Histone deacetylase inhibitors stimulate mitochondrial HMG-CoA synthase gene expression via a promoter proximal Sp1 site.

Nucleic Acids Res 2003 Mar;31(6):1693-703

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Av. Diagonal 643, 08028 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC152864PMC
http://dx.doi.org/10.1093/nar/gkg262DOI Listing
March 2003

Down-regulation of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by insulin: the role of the forkhead transcription factor FKHRL1.

Biochem J 2002 Aug;366(Pt 1):289-97

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Avda. Diagonal, 643, E-08028 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20020598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222772PMC
August 2002

Pig liver carnitine palmitoyltransferase. Chimera studies show that both the N- and C-terminal regions of the enzyme are important for the unusual high malonyl-CoA sensitivity.

J Biol Chem 2002 Mar 14;277(12):10044-9. Epub 2002 Jan 14.

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, 08028 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109976200DOI Listing
March 2002