Diego Arango

Diego Arango

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Diego Arango

Diego Arango

Publications by authors named "Diego Arango"

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Tumor Expression of Cyclin-Dependent Kinase 5 (Cdk5) Is a Prognostic Biomarker and Predicts Outcome of Oxaliplatin-Treated Metastatic Colorectal Cancer Patients.

Cancers (Basel) 2019 Oct 11;11(10). Epub 2019 Oct 11.

Program of predictive and personalized cancer medicine (PMPPC) Germans Trias i Pujol Research Institute (IGTP), Ctra. Can Ruti-Camí de les escoles s/n, 08916 Badalona, Spain.

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http://dx.doi.org/10.3390/cancers11101540DOI Listing
October 2019

Nanotechnology is an important strategy for combinational innovative chemo-immunotherapies against colorectal cancer.

J Control Release 2019 Aug 19;307:108-138. Epub 2019 Jun 19.

Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2019.06.017DOI Listing
August 2019

Pivotal Role of AKT2 during Dynamic Phenotypic Change of Breast Cancer Stem Cells.

Cancers (Basel) 2019 Jul 26;11(8). Epub 2019 Jul 26.

Drug Delivery and Targeting Group, Molecular Biology and Biochemistry Research Centre for Nanomedicine (CIBBIM-Nanomedicine), Vall d'Hebron Institut de Recerca, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.

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http://dx.doi.org/10.3390/cancers11081058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721305PMC
July 2019

Dynamism, Sensitivity, and Consequences of Mesenchymal and Stem-Like Phenotype of Cancer Cells.

Stem Cells Int 2018 10;2018:4516454. Epub 2018 Oct 10.

Drug Delivery and Targeting Group, CIBBIM-Nanomedicine, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, 08035 Barcelona, Spain.

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https://www.hindawi.com/journals/sci/2018/4516454/
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http://dx.doi.org/10.1155/2018/4516454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199882PMC
October 2018

Mechanisms of inactivation of the tumour suppressor gene RHOA in colorectal cancer.

Br J Cancer 2018 01 5;118(1):106-116. Epub 2017 Dec 5.

Group of Biomedical Research in Digestive Tract Tumors, CIBBIM-Nanomedicine, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB), Barcelona 08035, Spain.

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http://dx.doi.org/10.1038/bjc.2017.420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765235PMC
January 2018

Investigation of the role of tyrosine kinase receptor EPHA3 in colorectal cancer.

Sci Rep 2017 02 7;7:41576. Epub 2017 Feb 7.

Group of Biomedical Research in Digestive Tract Tumors, CIBBIM-Nanomedicine, Vall d'Hebron University Hospital, Research Institute (VHIR), Universitat Autònoma de Barcelona, Passeig Vall d'Hebron, 119-129, 08035 Barcelona, Spain.

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http://dx.doi.org/10.1038/srep41576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294649PMC
February 2017

Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells.

Mol Cancer Ther 2016 06 16;15(6):1217-26. Epub 2016 Mar 16.

Olivia Newton-John Cancer Research Institute and La Trobe University School of Cancer Medicine, Melbourne, Victoria, Australia. Ludwig Institute for Cancer Research, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0724DOI Listing
June 2016

Cancer stem cells and personalized cancer nanomedicine.

Nanomedicine (Lond) 2016 Feb 20;11(3):307-20. Epub 2016 Jan 20.

Drug Delivery & Targeting Group; CIBBIM-Nanomedicine, Vall d'Hebron Institut de Recerca (VHIR), Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.

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http://dx.doi.org/10.2217/nnm.15.200DOI Listing
February 2016

Fluorescent CSC models evidence that targeted nanomedicines improve treatment sensitivity of breast and colon cancer stem cells.

Nanomedicine 2015 Nov 31;11(8):1883-92. Epub 2015 Jul 31.

Drug Delivery and Targeting Group, CIBBIM Nanomedicine, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2015.07.009DOI Listing
November 2015

Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment.

Clin Cancer Res 2015 Aug 5;21(16):3695-704. Epub 2015 May 5.

Group of Molecular Oncology, CIBBIM-Nanomedicine, Vall d'Hebron University Hospital Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain. CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Zaragoza, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2457DOI Listing
August 2015

Myo5b knockout mice as a model of microvillus inclusion disease.

Sci Rep 2015 Jul 23;5:12312. Epub 2015 Jul 23.

1] Group of Molecular Oncology, CIBBIM-Nanomedicine, Vall d'Hebron University Hospital Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain [2] CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Zaragoza, Spain.

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http://dx.doi.org/10.1038/srep12312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511872PMC
July 2015

PTPRD is homozygously deleted and epigenetically downregulated in human hepatocellular carcinomas.

OMICS 2015 Apr;19(4):220-9

1 Department of Molecular Biology and Genetics, Bülent Ecevit University , Zonguldak, Turkey .

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http://dx.doi.org/10.1089/omi.2015.0010DOI Listing
April 2015

RHOA inactivation enhances Wnt signalling and promotes colorectal cancer.

Nat Commun 2014 Nov 21;5:5458. Epub 2014 Nov 21.

1] Group of Molecular Oncology, CIBBIM-Nanomedicine, Vall d'Hebron University Hospital, Research Institute (VHIR), Universitat Autònoma de Barcelona, Passeig Vall d'Hebron, 119-129, Barcelona 08035, Spain [2] CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), 28029 Barcelona, Spain.

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http://dx.doi.org/10.1038/ncomms6458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255233PMC
November 2014

Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.

Cancer Res 2014 Jun 22;74(12):3238-47. Epub 2014 Apr 22.

Authors' Affiliations: Ludwig Institute for Cancer Research; Systems Biology and Personalised Medicine Division; Structural Biology Division; Walter and Eliza Hall Institute of Medical Research; Faculty of Medicine, Dentistry and Health Sciences, Department of Medical Biology, University of Melbourne, Parkville; VLSCI Life Sciences Computation Centre, a collaboration between Melbourne, Monash and LaTrobe Universities, c/o The University of Melbourne, Carlton; Oncogenic Transcription Laboratory, Ludwig Institute for Cancer Research, Austin, VIC, Australia; Cancer and Population Studies Group, Queensland Institute of Medical Research, Herston, QLD, Australia; Group of Molecular Oncology, CIBBIM-Nanomedicine, Vall d'Hebron University Hospital, Research Institute (VHIR), Universitat Autònoma de Barcelona, Passeig Vall d'Hebron, 119-129, 08035 Barcelona; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN); Spain; Ludwig Collaborative Laboratory for Cancer Biology and Therapy, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; Ludwig Institute for Cancer Research Ltd., New York, New York; Cancer and Immunogenetics Laboratory, Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford; and Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, Oxford, United KingdomAuthors' Affiliations: Ludwig Institute for Cancer Research; Systems Biology and Personalised Medicine Division; Structural Biology Division; Walter and Eliza Hall Institute of Medical Research; Faculty of Medicine, Dentistry and Health Sciences, Department of Medical Biology, University of Melbourne, Parkville; VLSCI Life Sciences Computation Centre, a collaboration between Melbourne, Monash and LaTrobe Universities, c/o The University of Melbourne, Carlton; Oncogenic Transcription Laboratory, Ludwig Institute for Cancer Research, Austin, VIC, Australia; Cancer and Population Studies

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0013DOI Listing
June 2014

Brush border myosin Ia inactivation in gastric but not endometrial tumors.

Int J Cancer 2013 Apr 20;132(8):1790-9. Epub 2012 Oct 20.

Group of Molecular Oncology, CIBBIM-Nanomedicine, Vall d'Hebron University Hospital Research Institute, Universitat Autònoma de Barcelona, Passeig Vall d'Hebron 119-129, Barcelona, Spain.

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http://dx.doi.org/10.1002/ijc.27856DOI Listing
April 2013

Human SMC2 protein, a core subunit of human condensin complex, is a novel transcriptional target of the WNT signaling pathway and a new therapeutic target.

J Biol Chem 2012 Dec 24;287(52):43472-81. Epub 2012 Oct 24.

Drug Delivery and Targeting Group, Molecular Biology and Biochemistry Research Centre for Nanomedicine (CIBBIM-Nanomedicine), Vall d'Hebron Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona 08035 Spain.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M112.428466
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http://dx.doi.org/10.1074/jbc.M112.428466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527934PMC
December 2012

Villin expression is frequently lost in poorly differentiated colon cancer.

Am J Pathol 2012 Apr 18;180(4):1509-21. Epub 2012 Feb 18.

Molecular Biology and Biochemistry Research Center-Nanomedicine, Vall d'Hebron University Hospital Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.ajpath.2012.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426554PMC
April 2012

Brush border myosin Ia has tumor suppressor activity in the intestine.

Proc Natl Acad Sci U S A 2012 Jan 18;109(5):1530-5. Epub 2012 Jan 18.

Group of Molecular Oncology, and Group of Drug Delivery and Targeting, Centro de Investigaciones en Bioquímica y Biología Molecular-Nanomedicine, Vall d'Hebron University Hospital Research Institute, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.

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http://dx.doi.org/10.1073/pnas.1108411109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277176PMC
January 2012

[Population dynamics of the palm Euterpe oleracea (Arecaceae) from flooded forests in Choco, Colombian Pacific].

Rev Biol Trop 2010 Mar;58(1):465-81

Departamento de Ciencias Forestales, Universidad Nacional de Colombia, Sede Medellín, A.A. 1027 Medellín, Colombia.

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March 2010

Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer.

Clin Cancer Res 2009 Dec;15(24):7642-7651

Authors' Affiliations: Ludwig Colon Cancer Initiative Laboratory, Ludwig Institute for Cancer Research; Anatomic Pathology Department, Royal Melbourne Hospital, Parkville, Victoria, Australia; Department of Clinical Pharmacology, University of Oxford, Oxford, United Kingdom; Department of Medical Genetics, Biomedicum, University of Helsinki, Helsinki, Finland; Group of Molecular Oncology, Nanomedicine Research Program, Molecular Biology and Biochemistry Research Center (Centro de Investigación Bioquímica y Biología Molecular), Vall d'Hebron Hospital Research Institute, Barcelona, Spain; Molecular Diagnostic Laboratory, Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark; and GI Surgical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-1431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920750PMC
December 2009

The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.

Cancer Res 2009 Sep 8;69(18):7430-8. Epub 2009 Sep 8.

Group of Molecular Oncology, Biochemistry Research Center (CIBBIM-Nanomedicine) and Department of Pathology, Vall d'Hebron Hospital, Barcelona, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-0706DOI Listing
September 2009

EPH receptors in cancer.

Histol Histopathol 2008 08;23(8):1011-23

Drug Delivery and Targeting Group, Nanomedicine Program, Molecular Biology and Biochemistry Research Center (CIBBIM), Vall d'Hebron Hospital Research Institute, Barcelona, Spain.

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http://dx.doi.org/10.14670/HH-23.1011DOI Listing
August 2008

Unregulated smooth-muscle myosin in human intestinal neoplasia.

Proc Natl Acad Sci U S A 2008 Apr 7;105(14):5513-8. Epub 2008 Apr 7.

Department of Medical Genetics and Division of Pathology, HUSLAB and Haartman Institute, Helsinki University Central Hospital and Genome Scale Biology Program, Biomedicum Helsinki, University of Helsinki, 00014, Helsinki, Finland.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0801213105
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http://dx.doi.org/10.1073/pnas.0801213105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291082PMC
April 2008

Germline hypermethylation of the APC promoter is not a frequent cause of familial adenomatous polyposis in APC/MUTYH mutation negative families.

Int J Cancer 2008 Mar;122(6):1422-5

Molecular Oncology Group, Molecular Biology and Biochemistry Research Center (CIBBIM), Nanomedicine Research Program, Vall d'Hebron Hospital Research Institute, Barcelona, Spain.

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http://dx.doi.org/10.1002/ijc.23247DOI Listing
March 2008

Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer.

J Biol Chem 2006 May 13;281(19):13548-58. Epub 2006 Mar 13.

Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA.

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http://dx.doi.org/10.1074/jbc.M510023200DOI Listing
May 2006

Decrease in c-Myc activity enhances cancer cell sensitivity to vinblastine.

Anticancer Drugs 2006 Feb;17(2):181-7

CNRS FRE 2737, UFR Pharmacie, University of La Mediterranée, Marseille, France.

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http://dx.doi.org/10.1097/00001813-200602000-00009DOI Listing
February 2006

Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors.

Cancer Res 2005 Nov;65(22):10170-3

Molecular Oncology and Aging Group, Molecular Biology and Biochemistry Research Center (CIBBIM), Valle Hebron Hospital Research Institute, Barcelona, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-2580DOI Listing
November 2005

7q deletion mapping and expression profiling in uterine fibroids.

Oncogene 2005 Sep;24(43):6545-54

Department of Medical Genetics, University of Helsinki, PO Box 63 (Haartmaninkatu 8), Biomedicum Helsinki, FIN-00014, Finland.

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http://dx.doi.org/10.1038/sj.onc.1208784DOI Listing
September 2005

SMAD4 levels and response to 5-fluorouracil in colorectal cancer.

Clin Cancer Res 2005 Sep;11(17):6311-6

Department of Medical Genetics, Biomedicum Helsinki, Haartman Institute, University of Helsinki, Finland.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-0244DOI Listing
September 2005

SMAD4 as a prognostic marker in colorectal cancer.

Clin Cancer Res 2005 Apr;11(7):2606-11

Centre d'Investigacions en Bioquimica i Biologia Molecular, Hospital Universitari Vall d'Hebron, Barcelona, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-1458DOI Listing
April 2005

Customizing chemotherapy for colon cancer: the potential of gene expression profiling.

Drug Resist Updat 2004 Jun;7(3):209-18

Department of Oncology, Montefiore Medical Center, Albert Einstein Cancer Center, 111, East 210th Street, Bronx, NY 10467, USA.

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http://dx.doi.org/10.1016/j.drup.2004.05.001DOI Listing
June 2004

Tumor necrosis factor-alpha related gene response to Epothilone B in ovarian cancer.

Gynecol Oncol 2004 Apr;93(1):19-26

Albert Einstein Cancer Center and Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1016/j.ygyno.2003.11.058DOI Listing
April 2004

Gene expression profiling-based prediction of response of colon carcinoma cells to 5-fluorouracil and camptothecin.

Cancer Res 2003 Dec;63(24):8791-812

Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA.

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December 2003

Oncogenic Ki-ras inhibits the expression of interferon-responsive genes through inhibition of STAT1 and STAT2 expression.

J Biol Chem 2003 Nov 12;278(47):46278-87. Epub 2003 Sep 12.

Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, 111 E. 210th Street, Bronx, NY 10467, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M304721200
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http://dx.doi.org/10.1074/jbc.M304721200DOI Listing
November 2003

TR3/Nur77 in colon cancer cell apoptosis.

Cancer Res 2003 Sep;63(17):5401-7

Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA.

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September 2003

Microarray analysis in the clinical management of cancer.

Hematol Oncol Clin North Am 2003 Apr;17(2):377-87

Montefiore Medical Center Albert Einstein Cancer Center, Department of Oncology, HofJeimer Building, Room 509, 111 East 210th Street, Bronx, NY 10467, USA.

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April 2003

Short chain fatty acids and colon cancer.

J Nutr 2002 Dec;132(12):3804S-3808S

Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, NY 10467, USA.

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http://dx.doi.org/10.1093/jn/132.12.3804SDOI Listing
December 2002

Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention.

Cancer Res 2002 Nov;62(21):6006-10

Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA.

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November 2002

A gene expression profile that defines colon cell maturation in vitro.

Cancer Res 2002 Aug;62(16):4791-804

Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, New York 10467, USA.

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August 2002