Diane L DeHaven-Hudkins

Diane L DeHaven-Hudkins

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Diane L DeHaven-Hudkins

Diane L DeHaven-Hudkins

Publications by authors named "Diane L DeHaven-Hudkins"

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16Publications

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The involvement of the mu-opioid receptor in gastrointestinal pathophysiology: therapeutic opportunities for antagonism at this receptor.

Pharmacol Ther 2008 Jan 16;117(1):162-87. Epub 2007 Oct 16.

Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

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http://dx.doi.org/10.1016/j.pharmthera.2007.09.007DOI Listing
January 2008

Novel malonamide derivatives as potent kappa opioid receptor agonists.

Bioorg Med Chem Lett 2007 Apr 25;17(7):1951-5. Epub 2007 Jan 25.

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

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http://dx.doi.org/10.1016/j.bmcl.2007.01.053DOI Listing
April 2007

The selective mu opioid receptor antagonist, alvimopan, improves delayed GI transit of postoperative ileus in rats.

Brain Res 2006 Aug 22;1102(1):63-70. Epub 2006 Jun 22.

Department of Surgery, Duke University Medical Center, Surgical Service 112, VA Medical Center, Durham, NC 27705, USA.

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http://dx.doi.org/10.1016/j.brainres.2006.02.092DOI Listing
August 2006

Novel phenylamino acetamide derivatives as potent and selective kappa opioid receptor agonists.

Bioorg Med Chem Lett 2006 Feb 2;16(3):645-8. Epub 2005 Nov 2.

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

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http://dx.doi.org/10.1016/j.bmcl.2005.10.034DOI Listing
February 2006

Amino acid conjugates as kappa opioid receptor agonists.

Bioorg Med Chem Lett 2005 Mar;15(5):1279-82

Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

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http://dx.doi.org/10.1016/j.bmcl.2005.01.038DOI Listing
March 2005

Azepinone as a conformational constraint in the design of kappa-opioid receptor agonists.

Bioorg Med Chem Lett 2004 Nov;14(22):5693-7

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

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http://dx.doi.org/10.1016/j.bmcl.2004.08.041DOI Listing
November 2004

Peripherally restricted opioid drugs: advances and retreats.

Curr Opin Anaesthesiol 2003 Oct;16(5):541-5

Adolor Corporation, Exton, Pennsylvania 19341-1127, USA.

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http://dx.doi.org/10.1097/00001503-200310000-00016DOI Listing
October 2003

Antipruritic and antihyperalgesic actions of loperamide and analogs.

Life Sci 2002 Oct;71(23):2787-96

Department of Pharmacology, Adolor Corporation, 371 Phoenixville Pike, Malvern, PA 19355, USA.

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http://dx.doi.org/10.1016/s0024-3205(02)02102-1DOI Listing
October 2002

Effect of kappa opioid agonists on visceral nociception induced by uterine cervical distension in rats.

Pain 2002 Mar;96(1-2):13-22

Department of Anesthesiology and Intensive Care Medicine, Karl Franzens-University, Graz, Austria.

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http://dx.doi.org/10.1016/s0304-3959(01)00398-0DOI Listing
March 2002