Diana Karpman

Diana Karpman

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Diana Karpman

Diana Karpman

Publications by authors named "Diana Karpman"

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Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism.

Sci Rep 2019 Oct 7;9(1):14362. Epub 2019 Oct 7.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1038/s41598-019-50692-1DOI Listing
October 2019

Blockade of the kallikrein-kinin system reduces endothelial complement activation in vascular inflammation.

EBioMedicine 2019 Sep 20;47:319-328. Epub 2019 Aug 20.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.08.020DOI Listing
September 2019

[A case of quetiapine-induced congenital thrombotic thrombocytopenic purpura, atypical phenotype diagnosed in adulthood].

Lakartidningen 2019 Feb 12;116. Epub 2019 Feb 12.

Institution för kliniska vetenskaper, Lunds Universitet, Avdelning för pediatrik Lund, Sweden Institution för kliniska vetenskaper, Lunds Universitet, Avdelning för pediatrik Lund, Sweden.

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February 2019

Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases.

Pediatr Nephrol 2019 01 27;34(1):11-30. Epub 2017 Nov 27.

Department of Pediatrics, Clinical Sciences Lund, Lund University, 22185, Lund, Sweden.

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http://link.springer.com/10.1007/s00467-017-3816-z
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http://dx.doi.org/10.1007/s00467-017-3816-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244861PMC
January 2019

Aliskiren inhibits renin-mediated complement activation.

Kidney Int 2018 10 5;94(4):689-700. Epub 2018 Jun 5.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2018.04.004DOI Listing
October 2018

Microvesicle Involvement in Shiga Toxin-Associated Infection.

Toxins (Basel) 2017 11 19;9(11). Epub 2017 Nov 19.

Department of Pediatrics, Clinical Sciences Lund, Lund University, 22184 Lund, Sweden.

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http://dx.doi.org/10.3390/toxins9110376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705991PMC
November 2017

Extracellular vesicles in renal disease.

Nat Rev Nephrol 2017 Sep 24;13(9):545-562. Epub 2017 Jul 24.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Klinikgatan 28, 22184 Lund, Sweden.

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http://dx.doi.org/10.1038/nrneph.2017.98DOI Listing
September 2017

Thrombotic microangiopathy mimicking membranoproliferative glomerulonephritis.

Nephrol Dial Transplant 2017 03;32(3):584

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1093/ndt/gfx013DOI Listing
March 2017

Haemolytic uraemic syndrome.

J Intern Med 2017 02 10;281(2):123-148. Epub 2016 Oct 10.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1111/joim.12546DOI Listing
February 2017

Neutrophil Protease Cleavage of Von Willebrand Factor in Glomeruli - An Anti-thrombotic Mechanism in the Kidney.

EBioMedicine 2017 Feb 24;16:302-311. Epub 2017 Jan 24.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.01.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474509PMC
February 2017

Orphan drug policies and use in pediatric nephrology.

Pediatr Nephrol 2017 01 13;32(1):1-6. Epub 2016 Oct 13.

Department of Clinical Chemistry and Pharmacology, Laboratory Medicine Lund, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1007/s00467-016-3520-4DOI Listing
January 2017

Microvesicle transfer of kinin B1-receptors is a novel inflammatory mechanism in vasculitis.

Kidney Int 2017 01 1;91(1):96-105. Epub 2016 Dec 1.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2016.09.023DOI Listing
January 2017

Complement contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome.

Kidney Int 2016 10;90(4):726-9

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1016/j.kint.2016.07.002DOI Listing
October 2016

Early Terminal Complement Blockade and C6 Deficiency Are Protective in Enterohemorrhagic Escherichia coli-Infected Mice.

J Immunol 2016 08 15;197(4):1276-86. Epub 2016 Jul 15.

Department of Pediatrics, Clinical Sciences Lund, Lund University, 22185 Lund, Sweden;

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http://dx.doi.org/10.4049/jimmunol.1502377DOI Listing
August 2016

Eculizumab treatment for rescue of renal function in IgA nephropathy.

Pediatr Nephrol 2014 Nov 13;29(11):2225-8. Epub 2014 Jun 13.

Section of Pediatric Nephrology, Department of Pediatric and Adolescent Medicine, Skåne University Hospital, Lund, Sweden.

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http://dx.doi.org/10.1007/s00467-014-2863-yDOI Listing
November 2014

Eculizumab in an anephric patient with atypical haemolytic uraemic syndrome and advanced vascular lesions.

Nephrol Dial Transplant 2013 Nov 5;28(11):2899-907. Epub 2013 Sep 5.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1093/ndt/gft340DOI Listing
November 2013

Ouabain protects against Shiga toxin-triggered apoptosis by reversing the imbalance between Bax and Bcl-xL.

J Am Soc Nephrol 2013 Sep 6;24(9):1413-23. Epub 2013 Jun 6.

Department of Women's and Children's Health, Karolinska Institutet, Astrid Lindgren Children's Hospital, Research Lab, Stockholm, Sweden.

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http://www.jasn.org/cgi/doi/10.1681/ASN.2012101044
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http://dx.doi.org/10.1681/ASN.2012101044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752948PMC
September 2013

The antimicrobial peptide cathelicidin protects mice from Escherichia coli O157:H7-mediated disease.

PLoS One 2012 15;7(10):e46476. Epub 2012 Oct 15.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0046476PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471911PMC
March 2013

Neonatal onset atypical hemolytic uremic syndrome successfully treated with eculizumab.

Pediatr Nephrol 2013 Jan 6;28(1):155-8. Epub 2012 Sep 6.

Department of Pediatric Nephrology, Hacettepe University Faculty of Medicine, 06100 Sihhiye, Ankara, Turkey.

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http://dx.doi.org/10.1007/s00467-012-2296-4DOI Listing
January 2013

Editorial commentary: Escherichia coli O104:H4 and hemolytic uremic syndrome: the analysis begins.

Clin Infect Dis 2012 Sep 5;55(6):760-3. Epub 2012 Jun 5.

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http://dx.doi.org/10.1093/cid/cis533DOI Listing
September 2012

Shiga toxin pathogenesis: kidney complications and renal failure.

Curr Top Microbiol Immunol 2012 ;357:105-36

Department of Microbiology and Immunology, University of Maryland, School of Medicine, 685 West Baltimore Street, HSF-I Suite 380, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1007/82_2011_172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779650PMC
April 2012

Intestinal damage in enterohemorrhagic Escherichia coli infection.

Pediatr Nephrol 2011 Nov 1;26(11):2059-71. Epub 2010 Sep 1.

Department of Pediatrics, Clinical Sciences Lund, Lund University, 22185 Lund, Sweden.

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http://dx.doi.org/10.1007/s00467-010-1616-9DOI Listing
November 2011

Thrombotic microangiopathy mimicking membranoproliferative glomerulonephritis.

Nephrol Dial Transplant 2011 Oct 1;26(10):3399-403. Epub 2011 Aug 1.

Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.

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http://dx.doi.org/10.1093/ndt/gfr422DOI Listing
October 2011

Kinin system activation in vasculitis.

Acta Paediatr 2011 Jul 8;100(7):950-7. Epub 2011 Apr 8.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1111/j.1651-2227.2011.02266.xDOI Listing
July 2011

Cross-reactive protection against enterohemorrhagic Escherichia coli infection by enteropathogenic E. coli in a mouse model.

Infect Immun 2011 Jun 14;79(6):2224-33. Epub 2011 Mar 14.

Department of Pediatrics, Clinical Sciences Lund, Lund University, 22185 Lund, Sweden.

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http://dx.doi.org/10.1128/IAI.01024-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125830PMC
June 2011

Hyperfiltration evaluated by glomerular filtration rate at diagnosis in children with cancer.

Pediatr Blood Cancer 2011 May 16;56(5):762-6. Epub 2011 Jan 16.

Division of Oncology-Haematology, Childhood Cancer Research Unit, Lund University, Skåne University Hospital, Lund, Sweden.

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http://dx.doi.org/10.1002/pbc.22971DOI Listing
May 2011

Complement activation on platelet-leukocyte complexes and microparticles in enterohemorrhagic Escherichia coli-induced hemolytic uremic syndrome.

Blood 2011 May 29;117(20):5503-13. Epub 2011 Mar 29.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1182/blood-2010-09-309161DOI Listing
May 2011

IgA nephropathy associated with a novel N-terminal mutation in factor H.

Eur J Pediatr 2011 Jan 24;170(1):107-10. Epub 2010 Aug 24.

Department of Pediatrics, Clinical Sciences Lund, Lund University, 22185 Lund, Sweden.

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http://dx.doi.org/10.1007/s00431-010-1279-3DOI Listing
January 2011

Antibody response to IgA-binding streptococcal M proteins in children with IgA nephropathy.

Nephrol Dial Transplant 2010 Oct 17;25(10):3434-6. Epub 2010 Jun 17.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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https://academic.oup.com/ndt/article-lookup/doi/10.1093/ndt/
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http://dx.doi.org/10.1093/ndt/gfq346DOI Listing
October 2010

Pathophysiology of typical hemolytic uremic syndrome.

Semin Thromb Hemost 2010 Sep 23;36(6):575-85. Epub 2010 Sep 23.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1055/s-0030-1262879DOI Listing
September 2010

Tissue deposits of IgA-binding streptococcal M proteins in IgA nephropathy and Henoch-Schonlein purpura.

Am J Pathol 2010 Feb 7;176(2):608-18. Epub 2010 Jan 7.

Department of Pediatrics, Clinical Sciences Lund, Lund University, 22185 Lund, Sweden.

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http://dx.doi.org/10.2353/ajpath.2010.090428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808069PMC
February 2010

Biologically active ADAMTS13 is expressed in renal tubular epithelial cells.

Pediatr Nephrol 2010 Jan;25(1):87-96

Department of Pediatrics, Clinical Sciences Lund, Lund University, 22185 Lund, Sweden.

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http://dx.doi.org/10.1007/s00467-009-1262-2DOI Listing
January 2010

A novel mutation in the complement regulator clusterin in recurrent hemolytic uremic syndrome.

Mol Immunol 2009 Jul 15;46(11-12):2236-43. Epub 2009 May 15.

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1016/j.molimm.2009.04.012DOI Listing
July 2009

The contact/kinin and complement systems in vasculitis.

APMIS Suppl 2009 Jun(127):48-54

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1111/j.1600-0463.2009.02477.xDOI Listing
June 2009

Molecular basis of ADAMTS13 dysfunction in thrombotic thrombocytopenic purpura.

Pediatr Nephrol 2009 Mar 20;24(3):447-58. Epub 2008 Sep 20.

Department of Pediatrics, Clinical Sciences Lund, Lund University, 22185, Lund, Sweden.

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http://dx.doi.org/10.1007/s00467-008-0986-8DOI Listing
March 2009

Shiga toxin-mediated disease in MyD88-deficient mice infected with Escherichia coli O157:H7.

Am J Pathol 2008 Nov 2;173(5):1428-39. Epub 2008 Oct 2.

Department of Pediatrics, Clinical Sciences Lund, Lund University, 22185 Lund.

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http://dx.doi.org/10.2353/ajpath.2008.071218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570133PMC
November 2008

[Hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. Current perspectives on EHEC, complement mutations and ADAMTS13].

Authors:
Diana Karpman

Lakartidningen 2008 Apr 9-15;105(15):1096-101

Avdelning för pediatrik, Lunds universitet.

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June 2008

Characterization of mutations in complement factor I (CFI) associated with hemolytic uremic syndrome.

Mol Immunol 2008 Jan 26;45(1):95-105. Epub 2007 Jun 26.

Division of Rheumatology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.molimm.2007.05.004DOI Listing
January 2008

Reduced toll-like receptor 4 expression in children with asymptomatic bacteriuria.

J Infect Dis 2007 Aug 21;196(3):475-84. Epub 2007 Jun 21.

Department of Microbiology, Immunology, and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, 22362, Sweden.

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https://academic.oup.com/jid/article-lookup/doi/10.1086/5188
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http://dx.doi.org/10.1086/518893DOI Listing
August 2007

Inherited susceptibility to acute pyelonephritis: a family study of urinary tract infection.

J Infect Dis 2007 Apr 12;195(8):1227-34. Epub 2007 Mar 12.

Department of Microbiology, Immunology, and Glycobiology, Lund University, Lund, S-223 62, Sweden.

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http://dx.doi.org/10.1086/512620DOI Listing
April 2007

Anguish over angiopathy: hemolytic uremic syndrome.

Clin Immunol 2007 Feb 14;122(2):135-8. Epub 2006 Sep 14.

Clinical Sciences Lund, Department of Pediatrics, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1016/j.clim.2006.07.010DOI Listing
February 2007

A common origin of the 4143insA ADAMTS13 mutation.

Thromb Haemost 2006 Jul;96(1):3-6

University Medical Center Hamburg-Eppendorf, Department of Pediatric Hematology and Oncology, Martinistrasse 52, D-20246 Hamburg, Germany.

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http://dx.doi.org/10.1160/TH05-12-0817DOI Listing
July 2006

Platelet activation in hemolytic uremic syndrome.

Semin Thromb Hemost 2006 Mar;32(2):128-45

Department of Pediatrics, Clinical Sciences Lund, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1055/s-2006-939769DOI Listing
March 2006

Uropathogenic Escherichia coli as a model of host-parasite interaction.

Curr Opin Microbiol 2006 Feb 6;9(1):33-9. Epub 2006 Jan 6.

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S136952740500206
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http://dx.doi.org/10.1016/j.mib.2005.12.012DOI Listing
February 2006

Correct evaluation of renal glomerular filtration rate requires clearance assays.

Pediatr Nephrol 2002 Oct 8;17(10):847-51. Epub 2002 Aug 8.

Division of Oncology-Hematology, Department of Pediatrics, University Hospital, 221 85 Lund, Sweden.

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http://dx.doi.org/10.1007/s00467-002-0913-3DOI Listing
October 2002

Contact-system activation in children with vasculitis.

Lancet 2002 Aug;360(9332):535-41

Department of Paediatrics, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1016/S0140-6736(02)09743-XDOI Listing
August 2002

Human renal epithelial cells express iNOS in response to cytokines but not bacteria.

Kidney Int 2002 Feb;61(2):444-55

Department of Clinical Pharmacology, Lund University Hospital, Lund, Sweden.

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http://dx.doi.org/10.1046/j.1523-1755.2002.00138.xDOI Listing
February 2002