Dian-Shi Wang

Dian-Shi Wang

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Dian-Shi Wang

Dian-Shi Wang

Publications by authors named "Dian-Shi Wang"

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31Publications

496Reads

Dexmedetomidine Prevents Excessive γ-Aminobutyric Acid Type A Receptor Function after Anesthesia.

Anesthesiology 2018 Sep;129(3):477-489

From the Departments of Physiology (D.-S.W., K.K., G.L., F.M., J.W., I.L., Y.-F.X., N.K.C., A.F.-E., A.J.R., B.A.O.) Anesthesia (A.S., B.A.O.) Pharmacology and Toxicology (A.J.R.) Ophthalmology and Vision Science (J.M.S.) the Leslie Dan Faculty of Pharmacy (Y.-F.X., R.P.B.) University of Toronto, Toronto, Ontario, Canada; the Department of Anesthesia, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada (S.A., B.A.O.) the Center for Neuroscience and Connectomics, Korea Institute of Science and Technology, Seoul, Korea (J.W., C.J.L.) the Division of Vision Sciences, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada (D.C., J.M.S.).

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September 2018

High Concentrations of Tranexamic Acid Inhibit Ionotropic Glutamate Receptors.

Anesthesiology 2017 07;127(1):89-97

From the Departments of Physiology (I.L., D.-S.W., K.K., C.D.M., B.A.O.) and Anesthesia (C.D.M., B.A.O.), University of Toronto; Department of Anesthesia, Keenan Research Centre for Biomedical Science and the Li Ka Shing Knowledge Institute, St. Michael's Hospital (C.D.M.); and Department of Anesthesia, Sunnybrook Health Sciences Centre (B.A.O.), Toronto, Ontario, Canada.

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July 2017

Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.

N Engl J Med 2017 05;376(19):1891-2

Sunnybrook Health Sciences Centre, Toronto, ON, Canada

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May 2017

Ketamine Increases the Function of γ-Aminobutyric Acid Type A Receptors in Hippocampal and Cortical Neurons.

Anesthesiology 2017 04;126(4):666-677

From the Department of Physiology (D.-S.W., A.P., B.A.O.) and Anesthesia (B.A.O.), University of Toronto, Toronto, Ontario, Canada; Department of Anesthesia, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada (B.A.O); and Department of Anaesthesia, Universidad de Chile, Santiago, Chile (A.P.).

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April 2017

Preventing delirium: beyond dexmedetomidine.

Lancet 2017 03;389(10073):1009

Department of Anesthesia, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada; Department of Physiology, University of Toronto, Toronto, ON, Canada; Department of Anesthesia, University of Toronto, Toronto, ON, Canada.

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March 2017

δGABAA Receptors Are Necessary for Synaptic Plasticity in the Hippocampus: Implications for Memory Behavior.

Anesth Analg 2016 11;123(5):1247-1252

From the *Department of Psychology, and †Institute of Medical Science, University of Toronto, Toronto, Canada; ‡Department of Anesthesia, Sunnybrook Health Sciences Centre, Toronto, Canada; and Departments of §Anesthesia and ‖Physiology, University of Toronto, Toronto, Canada.

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November 2016

In Reply.

Anesthesiology 2016 09;125(3):604-5

University of Toronto, Toronto, Ontario, Canada.

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September 2016

Inflammation Increases Neuronal Sensitivity to General Anesthetics.

Anesthesiology 2016 Feb;124(2):417-27

From the Department of Anesthesia, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada (S.A., B.A.O.); and Departments of Anesthesia (S.A., B.A.O.), Physiology (D.-S.W., I.L., W.T.H.T., A.P., R.L.H., B.A.O.), Psychology (P.D.W.), and Medicine (L.M.-O., R.L.H.), University of Toronto, Toronto, Ontario, Canada.

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February 2016

Tranexamic acid-associated seizures: Causes and treatment.

Ann Neurol 2016 Jan 15;79(1):18-26. Epub 2015 Dec 15.

Departments of Physiology, University of Toronto.

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January 2016

Altered expression of δGABAA receptors in health and disease.

Neuropharmacology 2015 Jan 13;88:24-35. Epub 2014 Aug 13.

Institute of Medical Science, University of Toronto, Toronto, Ontario, M5S 1A8, Canada; Department of Physiology, University of Toronto, Toronto, Ontario, M5S 1A8, Canada; Department of Anesthesia, University of Toronto, Toronto, Ontario, M5S 1A8, Canada; Department of Anesthesia, Sunnybrook Health Sciences Centre, Toronto, Ontario, M4N 3M5, Canada. Electronic address:

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January 2015

Imbalance of HCN1 and HCN2 expression in hippocampal CA1 area impairs spatial learning and memory in rats with chronic morphine exposure.

Prog Neuropsychopharmacol Biol Psychiatry 2015 Jan 7;56:207-14. Epub 2014 Oct 7.

Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Institute of Brain Research, Huazhong University of Science and Technology, Wuhan 430030, China. Electronic address:

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January 2015

Hydrogen peroxide increases GABAA receptor-mediated tonic current in hippocampal neurons.

J Neurosci 2014 Aug;34(32):10624-34

Departments of Physiology and Anesthesia, University of Toronto, Toronto, Ontario M5S 1A8, Canada, Department of Anesthesia, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada, and

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August 2014

Acutely increasing δGABA(A) receptor activity impairs memory and inhibits synaptic plasticity in the hippocampus.

Front Neural Circuits 2013 17;7:146. Epub 2013 Sep 17.

Institute of Medical Science, University of Toronto Toronto, ON, Canada.

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April 2014

γ-aminobutyric acid type A receptors that contain the δ subunit promote memory and neurogenesis in the dentate gyrus.

Ann Neurol 2013 Oct 8;74(4):611-21. Epub 2013 Jul 8.

Institute of Medical Science, University of Toronto, Ontario, Canada.

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October 2013

Tranexamic acid concentrations associated with human seizures inhibit glycine receptors.

J Clin Invest 2012 Dec 26;122(12):4654-66. Epub 2012 Nov 26.

Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

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December 2012

Inhibition of learning and memory by general anesthetics.

Can J Anaesth 2011 Feb 23;58(2):167-77. Epub 2010 Dec 23.

Department of Anesthesia, University of Toronto, Rm. 3318, Medical Sciences Building, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

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February 2011

Mechanisms for picrotoxinin and picrotin blocks of alpha2 homomeric glycine receptors.

J Biol Chem 2007 Jun 3;282(22):16016-35. Epub 2007 Apr 3.

UMR CNRS 7102 Neurobiologie des Processus Adaptatifs, Université Pierre et Marie Curie, 9 Quai St. Bernard, 75252, Paris Cedex 05, France, and Center for Neuroscience Research, Children's National Medical Center, Washington DC 20010, USA.

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June 2007

Mechanisms for picrotoxin block of alpha2 homomeric glycine receptors.

J Biol Chem 2006 Feb 12;281(7):3841-55. Epub 2005 Dec 12.

Unité Mixte de Recherche, CNRS 7102, Neurobiologie des Processus Adaptatifs, Université Pierre et Marie Curie, Paris, France.

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February 2006

Inhibition of hypoxia-induced proliferation and collagen synthesis by vasonatrin peptide in cultured rat pulmonary artery smooth muscle cells.

Life Sci 2005 May;77(1):28-38

Department of Physiology, Fourth Military Medical University, No.17 West Changle Road, Xi'an 710032, China.

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May 2005

Suppression of kainate-evoked AMPA receptor mediated responses by lanthanum in rat sacral dorsal commissural neurons.

Neurosignals 2004 Sep-Oct;13(5):258-64

Department of Anatomy and K.K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an 710032, China.

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October 2004

Down-regulation of C-type natriuretic peptide receptor by vasonatrin peptide in cardiac myocytes and fibroblasts.

Acta Pharmacol Sin 2004 Apr;25(4):424-30

Department of Physiology, Fourth Military Medical University, Xi-an 710032, China.

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April 2004

Biphasic action of midazolam on GABAA receptor-mediated responses in rat sacral dorsal commissural neurons.

Biochem Biophys Res Commun 2003 Oct;309(4):893-9

Department of Anatomy, Fourth Military Medical University, Xi'an 710032, China.

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October 2003

Cu2+ suppresses GABA(A) receptor-mediated responses in rat sacral dorsal commissural neurons.

Neurosignals 2002 Nov-Dec;11(6):322-8

Department of Anatomy and KK Leung Brain Research Centre, Fourth Military Medical University, Xi'an, China.

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April 2003

Beta-alanine acts on glycine receptors in the rat sacral dorsal commissural neurons.

Int J Neurosci 2003 Mar;113(3):293-305

Department of Anatomy and K. K. Leung Brain Research Centre, Fourth Military Medical University, 17# West Changle Road, Xi'an, 710032, Shaanxi, China.

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March 2003

Postnatal changes in the overall postsynaptic currents evoked in CA1 pyramidal neurons of the rat hippocampus.

Life Sci 2002 Dec;72(4-5):341-53

Department of Physiology, Kurume University School of Medicine, 67 Asahi-machi, 830-0011, Kurume, Japan.

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December 2002

Cu(2+) inhibition of glycine-activated currents in rat sacral dorsal commissural neurons.

Neurosci Lett 2002 Aug;328(2):117-20

Department of Anatomy and K. K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an 710032, China.

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August 2002