Dhruv Chauhan

Dhruv Chauhan

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Dhruv Chauhan

Dhruv Chauhan

Publications by authors named "Dhruv Chauhan"

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7Publications

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BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages.

Cell Rep 2018 11;25(9):2354-2368.e5

Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183169
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http://dx.doi.org/10.1016/j.celrep.2018.10.087DOI Listing
November 2018

Activation of the NLRP3 Inflammasome by Hyaboron, a New Asymmetric Boron-Containing Macrodiolide from the Myxobacterium Hyalangium minutum.

ACS Chem Biol 2018 10 17;13(10):2981-2988. Epub 2018 Sep 17.

Department Microbial Drugs , Helmholtz Center for Infection Research (HZI) , Inhoffenstraße 7 , 38124 Braunschweig , Germany.

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http://dx.doi.org/10.1021/acschembio.8b00659DOI Listing
October 2018

The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3.

Cell 2017 Nov 12;171(5):1110-1124.e18. Epub 2017 Oct 12.

Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany; Center for Integrated Protein Science (CIPSM), Ludwig-Maximilians-Universität München, 81377 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.09.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901709PMC
November 2017

Human Monocytes Engage an Alternative Inflammasome Pathway.

Immunity 2016 Apr 29;44(4):833-46. Epub 2016 Mar 29.

Institute of Molecular Medicine, University Hospital Bonn, 53127 Bonn, Germany; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 München, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.01.012DOI Listing
April 2016

A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation.

J Biol Chem 2016 Jan 9;291(1):103-9. Epub 2015 Nov 9.

From the Institute of Molecular Medicine and the Gene Center and Department of Biochemistry, Ludwig-Maximilians-University Munich, 81377 Munich, Germany

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http://dx.doi.org/10.1074/jbc.C115.700492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697147PMC
January 2016

Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.

EMBO J 2014 Dec 25;33(24):2937-46. Epub 2014 Nov 25.

Institute of Molecular Medicine, University Hospital University of Bonn, Bonn, Germany

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http://dx.doi.org/10.15252/embj.201488726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282641PMC
December 2014