Dhavalkumar D Patel

Dhavalkumar D Patel

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Dhavalkumar D Patel

Dhavalkumar D Patel

Publications by authors named "Dhavalkumar D Patel"

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53Publications

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TNF-α-induced protein 3 (A20): The immunological rheostat.

J Allergy Clin Immunol 2018 08 1;142(2):401-402. Epub 2018 Jun 1.

New Medicines, UCB Biopharma, Braine-l'Alleud, Belgium, and Slough, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183078
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http://dx.doi.org/10.1016/j.jaci.2018.05.020DOI Listing
August 2018

Phase 2 to phase 3 clinical trial transitions: Reasons for success and failure in immunologic diseases.

J Allergy Clin Immunol 2017 09 12;140(3):685-687. Epub 2017 May 12.

Gilead Sciences, Foster City, Calif.

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http://dx.doi.org/10.1016/j.jaci.2017.04.029DOI Listing
September 2017

Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions.

Immunity 2015 Dec;43(6):1040-51

Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.immuni.2015.12.003DOI Listing
December 2015

Preclinical target validation using patient-derived cells.

Nat Rev Drug Discov 2015 Mar 20;14(3):149-50. Epub 2015 Feb 20.

Structural Genomics Consortium, Department of Medicine, Karolinska University Hospital and Karolinska Institutet, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1038/nrd4565DOI Listing
March 2015

Effect of IL-17A blockade with secukinumab in autoimmune diseases.

Ann Rheum Dis 2013 Apr 19;72 Suppl 2:ii116-23. Epub 2012 Dec 19.

Autoimmunity, Transplantation and Inflammation Disease Area, Novartis Institutes for BioMedical Research, Basel CH-4002, Switzerland.

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http://ard.bmj.com/content/72/suppl_2/iii116.full.pdf
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http://ard.bmj.com/cgi/doi/10.1136/annrheumdis-2012-202371
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http://dx.doi.org/10.1136/annrheumdis-2012-202371DOI Listing
April 2013

Enhanced Th17-cell responses render CCR2-deficient mice more susceptible for autoimmune arthritis.

PLoS One 2011 4;6(10):e25833. Epub 2011 Oct 4.

Department of Medicine, Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025833PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186765PMC
February 2012

Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN).

Clin Immunol 2008 Oct 26;129(1):115-22. Epub 2008 Jul 26.

Thurston Arthritis Research Center, Department of Medicine, Division of Rheumatology, Allergy and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.clim.2008.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637521PMC
October 2008

CX3CR1 deficiency impairs dendritic cell accumulation in arterial intima and reduces atherosclerotic burden.

Arterioscler Thromb Vasc Biol 2008 Feb 13;28(2):243-50. Epub 2007 Dec 13.

Thurston Arthritis Research Center and Department of Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599-7280, USA.

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http://dx.doi.org/10.1161/ATVBAHA.107.158675DOI Listing
February 2008

Ozone enhancement of lower airway allergic inflammation is prevented by gamma-tocopherol.

Free Radic Biol Med 2007 Oct 20;43(8):1176-88. Epub 2007 Jul 20.

Department of Pathobiology and Diagnostic Investigation, Michigan State University, 211 Food Safety and Toxicology Building, East Lansing, MI 48824, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2007.07.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465777PMC
October 2007

Defective antitumor responses in CX3CR1-deficient mice.

Int J Cancer 2007 Jul;121(2):316-22

Thurston Arthritis Research Center and the Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1002/ijc.22660DOI Listing
July 2007

Cetuximab-associated infusion reactions: pathology and management.

Oncology (Williston Park) 2006 Oct;20(11):1373-82; discussion 1382, 1392-4, 1397

Division of Hematology and Oncology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7280, USA.

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October 2006

CX3CR1 deficiency confers protection from intimal hyperplasia after arterial injury.

Arterioscler Thromb Vasc Biol 2006 Sep 29;26(9):2056-62. Epub 2006 Jun 29.

Department of Medicine, University of North Carolina at Chapel Hill, USA.

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http://dx.doi.org/10.1161/01.ATV.0000234947.47788.8cDOI Listing
September 2006

AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix.

Mol Immunol 2006 Feb 23;43(4):335-45. Epub 2005 Mar 23.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Colorado Health Sciences Center, 4200 East Ninth Ave. C-238, Denver, CO 80262, USA.

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http://dx.doi.org/10.1016/j.molimm.2005.02.018DOI Listing
February 2006

Chemokines and leukocyte trafficking in rheumatoid arthritis.

Pathophysiology 2006 Feb 27;13(1):1-14. Epub 2005 Dec 27.

Department of Medicine, Division of Rheumatology, Allergy, and Immunology, Thurston Arthritis Research Center, University of North Carolina, 3330 Thurston Bldg., CB#7280, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.pathophys.2005.11.001DOI Listing
February 2006

Suboptimal neurodevelopment in very preterm infants is related to fetal cardiovascular compromise in placental insufficiency.

Am J Obstet Gynecol 2005 Aug;193(2):414-20

Department of Pediatrics, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1016/j.ajog.2004.12.005DOI Listing
August 2005

Recycling of the membrane-anchored chemokine, CX3CL1.

J Biol Chem 2005 May 16;280(20):19858-66. Epub 2005 Mar 16.

The Hospital for Sick Children Research Institute and the University of Toronto, Canada.

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http://dx.doi.org/10.1074/jbc.M413073200DOI Listing
May 2005

Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis.

Mol Pharmacol 2005 Apr 5;67(4):1229-36. Epub 2005 Jan 5.

Howard Hughes Medical Institute, Departments of Medicine and Biochemistry, Box 3821, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1124/mol.104.006270DOI Listing
April 2005

Acute LPS inhalation in healthy volunteers induces dendritic cell maturation in vivo.

J Allergy Clin Immunol 2005 Feb;115(2):345-50

Center for Environmental Biology, Asthma, and Lung Biology, University of North Carolina at Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.jaci.2004.11.040DOI Listing
February 2005

The immune system in aging: roles of cytokines, T cells and NK cells.

Front Biosci 2005 Jan 1;10:192-215. Epub 2005 Jan 1.

Center for Demographic Studies, Duke University, 2117 Campus Drive Box 90408, Durham, NC 27708, USA.

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January 2005

Cadherin-11 provides specific cellular adhesion between fibroblast-like synoviocytes.

J Exp Med 2004 Dec;200(12):1673-9

Dept. of Medicine, Div. of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Smith Bldg., Rm. 552, One Jimmy Fund Way, Boston, MA 02115, USA.

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http://dx.doi.org/10.1084/jem.20041545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211995PMC
December 2004

Genomic-based therapy: targeting interleukin-1 for autoinflammatory diseases.

Arthritis Rheum 2004 Feb;50(2):345-9

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http://dx.doi.org/10.1002/art.20032DOI Listing
February 2004

Abnormal development of thymic dendritic and epithelial cells in human X-linked severe combined immunodeficiency.

Clin Immunol 2004 Jan;110(1):63-70

Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.clim.2003.09.002DOI Listing
January 2004

The chemokine CX3CL1 regulates NK cell activity in vivo.

Cell Immunol 2003 Oct;225(2):122-30

The Hospital for Sick Children Research Institute, and the University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.cellimm.2003.09.010DOI Listing
October 2003

Beta-arrestin-2 regulates the development of allergic asthma.

J Clin Invest 2003 Aug;112(4):566-74

Department of Medicine, Duke University Medical Center, Box 3821, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1172/JCI17265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC171386PMC
August 2003

T cell repertoire development in humans with SCID after nonablative allogeneic marrow transplantation.

J Immunol 2003 Mar;170(5):2711-8

Department of Immunology, Medicine, and Pediatrics, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.4049/jimmunol.170.5.2711DOI Listing
March 2003

B cell loss leading to remission in severe systemic lupus erythematosus.

J Rheumatol 2003 Feb;30(2):412-4

Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.

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February 2003

Multiplexed protein profiling on antibody-based microarrays by rolling circle amplification.

Curr Opin Biotechnol 2003 Feb;14(1):74-81

Molecular Staging Inc., 300 George Street, New Haven, CT 06511, USA.

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February 2003

Toll-like receptor 4 (TLR4)-deficient murine macrophage cell line as an in vitro assay system to show TLR4-independent signaling of Bacteroides fragilis lipopolysaccharide.

Infect Immun 2002 Sep;70(9):4892-6

Department of Internal Medicine, Section of Infectious Diseases, Wake Forest University Medical Center, Winston-Salem, NC, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC128243PMC
http://dx.doi.org/10.1128/iai.70.9.4892-4896.2002DOI Listing
September 2002

B cell-ablative therapy for the treatment of autoimmune diseases.

Arthritis Rheum 2002 Aug;46(8):1984-5

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http://doi.wiley.com/10.1002/art.10476
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http://dx.doi.org/10.1002/art.10476DOI Listing
August 2002

Cowpox virus encodes a fifth member of the tumor necrosis factor receptor family: a soluble, secreted CD30 homologue.

Proc Natl Acad Sci U S A 2002 Jun 28;99(12):8348-53. Epub 2002 May 28.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.122238599
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http://dx.doi.org/10.1073/pnas.122238599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC123070PMC
June 2002

Clustered charged amino acids of human adenosine deaminase comprise a functional epitope for binding the adenosine deaminase complexing protein CD26/dipeptidyl peptidase IV.

J Biol Chem 2002 May 18;277(22):19720-6. Epub 2002 Mar 18.

Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.M111901200DOI Listing
May 2002

CX3CR1 tyrosine sulfation enhances fractalkine-induced cell adhesion.

J Biol Chem 2002 May 21;277(22):19418-23. Epub 2002 Mar 21.

Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.M201396200DOI Listing
May 2002