Desmond A Schatz

Desmond A Schatz

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Desmond A Schatz

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Is It Time to Prioritize Diabetes Prevention in Practice?

J Am Board Fam Med 2019 Jul-Aug;32(4):457-459

From the Department of Health Services Research Management, and Policy, University of Florida, Gainesville, FL (AGM); Department of Community Health and Family Medicine, University of Florida, Gainesville (AGM); Department of Pediatrics, University of Florida, Gainesville (DAS); University of Florida Diabetes Institute, Gainesville (DAS).

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http://dx.doi.org/10.3122/jabfm.2019.04.190114DOI Listing
August 2019

Genetic risk for autoimmunity is associated with distinct changes in the human gut microbiome.

Nat Commun 2019 Aug 9;10(1):3621. Epub 2019 Aug 9.

Crown Princess Victoria's Children's Hospital, Region Östergötland, Division of Pediatrics, Linköping University, Linköping, SE 58185, Sweden.

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http://dx.doi.org/10.1038/s41467-019-11460-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689114PMC
August 2019

Enhanced Understanding of the Natural History of Pre-Type 1 Diabetes: Fundamental to Prevention.

Pediatr Endocrinol Rev 2019 Mar;16(3):359-368

Biomedical Sciences Building, J599, University of Florida Shands Hospital, 1600 SW Archer Road, Gainesville, FL 32603, E-mail:

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http://dx.doi.org/10.17458/per.vol16.2019.bs.pretype1diabetesDOI Listing
March 2019

Hospital time prior to death and pancreas histopathology: implications for future studies.

Diabetologia 2018 04 11;61(4):954-958. Epub 2017 Nov 11.

Department of Diabetes and Cancer Discovery Science, Diabetes and Metabolism Research Institute, City of Hope/Beckman Research Institute, 1500 East Duarte Road, Duarte, CA, 91010-3000, USA.

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http://dx.doi.org/10.1007/s00125-017-4494-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844815PMC
April 2018

Understanding Pre-Type 1 Diabetes: The Key to Prevention.

Front Endocrinol (Lausanne) 2018 6;9:70. Epub 2018 Mar 6.

Division of Endocrinology, Department of Pediatrics, University of Florida, Gainesville, FL, United States.

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http://dx.doi.org/10.3389/fendo.2018.00070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845548PMC
March 2018

Type 1 diabetes mellitus.

Nat Rev Dis Primers 2017 Mar 30;3:17016. Epub 2017 Mar 30.

Department of Clinical Sciences, Lund University, Skåne University Hospital, Jan Waldenströms gata 35, 20502 Malmö, Sweden.

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http://dx.doi.org/10.1038/nrdp.2017.16DOI Listing
March 2017

Factors That Influence the Quality of RNA From the Pancreas of Organ Donors.

Pancreas 2017 02;46(2):252-259

From the *Departments of Pathology, Immunology, & Laboratory Medicine, University of Florida, Gainesville, FL; †Department of Medicine, College of Medicine, University of Tennessee Health Science Center, Memphis, TN; ‡Diabetes Research Institute and Departments of Medicine, Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL; §Department of Information Sciences, ∥Division of Biostatistics, City of Hope, Duarte, CA; and ¶Department of Pediatrics, College of Medicine, University of Florida, Gainesville, FL.

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http://dx.doi.org/10.1097/MPA.0000000000000717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235995PMC
February 2017

Plant-based vaccines for oral delivery of type 1 diabetes-related autoantigens: Evaluating oral tolerance mechanisms and disease prevention in NOD mice.

Sci Rep 2017 02 13;7:42372. Epub 2017 Feb 13.

Departments of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1038/srep42372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304332PMC
February 2017

Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study.

Diabetes Care 2016 Sep 16;39(9):1535-42. Epub 2016 Jun 16.

Health Informatics Institute, Department of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, FL.

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http://dx.doi.org/10.2337/dc16-0181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001144PMC
September 2016

Diagnostic Dilemma: Clinical and Histological Abnormalities in a Hispanic Patient With Diabetes.

Diabetes Care 2016 09;39(9):1650-2

Department of Pediatrics, University of Florida, Gainesville, FL

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http://dx.doi.org/10.2337/dc16-0711DOI Listing
September 2016

Presumptive Type 1 Diabetes With Comorbidities and Rapid Progression Despite Numerous Insulin-Positive Islets.

Diabetes Care 2016 07;39(7):1292-4

Department of Pediatrics, University of Florida, Gainesville, FL

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http://dx.doi.org/10.2337/dc16-0737DOI Listing
July 2016

The DIPP project: 20 years of discovery in type 1 diabetes.

Pediatr Diabetes 2016 07;17 Suppl 22:5-7

University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1111/pedi.12398DOI Listing
July 2016

Educational Needs and Technological Preferences of Fathers of Youth With Type 1 Diabetes.

Diabetes Educ 2016 04 5;42(2):209-19. Epub 2016 Feb 5.

College of Nursing, University of Florida, Gainesville, Florida (Dr Albanese-O'Neill, Dr Elder)

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http://dx.doi.org/10.1177/0145721716628649DOI Listing
April 2016

Pancreatic duct hyperplasia/dysplasia in type 1 diabetes and pancreatic weight in individuals with and without diabetes. Reply to Kobayashi T, Aida K, Fukui T et al [letter] and Saisho Y [letter].

Diabetologia 2016 Apr 9;59(4):870-2. Epub 2016 Feb 9.

Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, POB 100275, 1395 Center Drive, Gainesville, FL, 32610, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047275PMC
http://dx.doi.org/10.1007/s00125-016-3889-4DOI Listing
April 2016

Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes.

Diabetes 2016 Mar 18;65(3):719-31. Epub 2015 Nov 18.

Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL Department of Pediatrics, University of Florida, Gainesville, FL.

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http://dx.doi.org/10.2337/db15-0779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764143PMC
March 2016

The influence of type 1 diabetes on pancreatic weight.

Diabetologia 2016 Jan 10;59(1):217-221. Epub 2015 Sep 10.

Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, POB 100275, 1395 Center Drive, Gainesville, FL, 32610, USA.

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http://link.springer.com/content/pdf/10.1007%2Fs00125-015-37
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http://link.springer.com/10.1007/s00125-015-3752-z
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http://dx.doi.org/10.1007/s00125-015-3752-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670792PMC
January 2016

Screening for T1D risk to reduce DKA is not economically viable.

Pediatr Diabetes 2015 Dec 22;16(8):565-72. Epub 2015 Sep 22.

Department of Pediatrics, University of Florida, 1600 SW Archer Road, Gainesville, FL, 32608, USA.

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http://dx.doi.org/10.1111/pedi.12313DOI Listing
December 2015

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study.

Diabetologia 2015 May 10;58(5):980-7. Epub 2015 Feb 10.

Department of Pediatrics, Morsani College of Medicine, University of South Florida, 3650 Spectrum Boulevard, Suite 100, Tampa, FL, 33612, USA,

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http://dx.doi.org/10.1007/s00125-015-3514-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393776PMC
May 2015

IgG4 antibodies in autoimmune polyglandular disease and IgG4-related endocrinopathies: pathophysiology and clinical characteristics.

Curr Opin Pediatr 2014 Aug;26(4):493-9

aDepartment of Pediatrics, Division of Pediatric Endocrinology bDepartments of Pathology, Immunology and Laboratory Medicine, Pediatrics, and Molecular Genetics and Microbiology, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1097/MOP.0000000000000107DOI Listing
August 2014

Healthcare transition from pediatric to adult medical homes in diabetes mellitus.

Endocr Pract 2014 Jul;20(7):715-21

Clinical Development, Lexicon Pharmaceuticals, The Woodlands, Texas.

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http://journals.aace.com/doi/abs/10.4158/EP13369.RA
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http://dx.doi.org/10.4158/EP13369.RADOI Listing
July 2014

Distribution of C-peptide and its determinants in North American children at risk for type 1 diabetes.

Diabetes Care 2014 Jul 23;37(7):1959-65. Epub 2014 Apr 23.

Pediatrics Epidemiology Center, College of Medicine, University of South Florida, Tampa, FL.

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http://care.diabetesjournals.org/lookup/doi/10.2337/dc13-260
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http://dx.doi.org/10.2337/dc13-2603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067394PMC
July 2014

The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings.

Pediatr Diabetes 2014 Feb 10;15(1):1-9. Epub 2013 Dec 10.

Diabetes Research Institute, University of Miami Miller School of Medicine, Miami, FL, USA; Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, University of Miami Miller School of Medicine, Miami, FL, USA; Department of Immunology and Microbiology, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1111/pedi.12097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282794PMC
February 2014

The autoimmune disease-associated SNP rs917997 of IL18RAP controls IFNγ production by PBMC.

J Autoimmun 2013 Aug 24;44:8-12. Epub 2013 Jul 24.

Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1016/j.jaut.2013.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775347PMC
August 2013

Update on global intervention studies in type 1 diabetes.

Endocrinol Metab Clin North Am 2012 Dec;41(4):695-712

Division of Endocrinology, Department of Pediatrics, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.ecl.2012.07.003DOI Listing
December 2012

The use of leptin as treatment for type 1 diabetes mellitus: counterpoint.

Pediatr Diabetes 2012 Feb 2;13(1):74-6. Epub 2011 Sep 2.

Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32611, USA.

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http://doi.wiley.com/10.1111/j.1399-5448.2011.00796.x
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http://dx.doi.org/10.1111/j.1399-5448.2011.00796.xDOI Listing
February 2012

Development of autoantibodies in the TrialNet Natural History Study.

Diabetes Care 2011 Sep 12;34(9):1897-901. Epub 2011 Jul 12.

University of South Florida, Pediatrics Epidemiology Center, Tampa, FL, USA.

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http://dx.doi.org/10.2337/dc11-0560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161292PMC
September 2011

Use of a precious resource: parental decision making about using autologous umbilical cord blood in studies involving young children with type 1 diabetes.

Contemp Clin Trials 2011 Jul 17;32(4):524-9. Epub 2011 Apr 17.

Department of Medical Humanities and Social Sciences, Florida State University College of Medicine, Tallahassee, FL 32306–4300, USA.

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http://dx.doi.org/10.1016/j.cct.2011.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129744PMC
July 2011

Long-term outcome of individuals treated with oral insulin: diabetes prevention trial-type 1 (DPT-1) oral insulin trial.

Diabetes Care 2011 Jul 24;34(7):1585-90. Epub 2011 May 24.

University of South Florida, Pediatrics Epidemiology Center, Tampa, Florida, USA.

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http://dx.doi.org/10.2337/dc11-0523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120180PMC
July 2011

Autoimmune markers in diabetes.

Clin Chem 2011 Feb 2;57(2):168-75. Epub 2010 Dec 2.

Department of Pathology, University of Florida, Gainesville, FL 32610-0275, USA.

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http://www.clinchem.org/cgi/doi/10.1373/clinchem.2010.148205
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http://dx.doi.org/10.1373/clinchem.2010.148205DOI Listing
February 2011

The pancreas in human type 1 diabetes.

Semin Immunopathol 2011 Jan 22;33(1):29-43. Epub 2010 May 22.

Department of Pathology, Immunology and Laboratory Medicine, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1007/s00281-010-0208-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022158PMC
January 2011

Butyrate and type 1 diabetes mellitus: can we fix the intestinal leak?

J Pediatr Gastroenterol Nutr 2010 Oct;51(4):414-7

Department of Pediatrics, University of Florida, Gainesville, FL 32610-0296, USA.

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http://dx.doi.org/10.1097/MPG.0b013e3181dd913aDOI Listing
October 2010

Type I diabetes. Preface.

Endocrinol Metab Clin North Am 2010 Sep 1;39(3):xvii-xviii. Epub 2010 Jul 1.

Division of Endocrinology, Department of Pediatrics, University of Florida, PO Box 100296, Gainsville, FL 32610, USA.

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http://dx.doi.org/10.1016/j.ecl.2010.05.012DOI Listing
September 2010

Efforts to prevent and halt autoimmune beta cell destruction.

Endocrinol Metab Clin North Am 2010 Sep;39(3):527-39

Division of Endocrinology, Department of Pediatrics, University of Florida, PO Box 100296, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1016/j.ecl.2010.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925042PMC
September 2010

Exendin-4 treatment of nonobese diabetic mice increases beta-cell proliferation and fractional insulin reactive area.

J Diabetes Complications 2010 May-Jun;24(3):163-7. Epub 2009 Feb 13.

Department of Pathology, University of Florida, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1016/j.jdiacomp.2008.12.004DOI Listing
July 2010

Challenges in developing endpoints for type 1 diabetes intervention studies.

Diabetes Metab Res Rev 2009 Nov;25(8):694-704

Department of Endocrinology and Diabetes, University Campus Bio-Medico, Rome, Italy.

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http://dx.doi.org/10.1002/dmrr.1002DOI Listing
November 2009

The road not taken: a path to curing type 1 diabetes?

Eur J Immunol 2009 Aug;39(8):2054-8

Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1002/eji.200939517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085751PMC
August 2009

Participant and parent experiences in the oral insulin study of the Diabetes Prevention Trial for Type 1 Diabetes.

Pediatr Diabetes 2009 May 24;10(3):177-83. Epub 2008 Sep 24.

Department of Medical Humanities and Social Sciences, Florida State University College of Medicine, Tallahassee, FL 2306-4300, USA.

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http://dx.doi.org/10.1111/j.1399-5448.2008.00463.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206940PMC
May 2009

CFTR mutations impart elevated immune reactivity in a murine model of cystic fibrosis related diabetes.

Cytokine 2008 Oct 7;44(1):154-9. Epub 2008 Sep 7.

Department of Pediatrics, University of Florida, College of Medicine, P.O. Box 100296, Gainesville, FL 32610, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S104346660800220
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http://dx.doi.org/10.1016/j.cyto.2008.07.468DOI Listing
October 2008

What's in a name? Thyroid autoimmunity in obese patients with T1D.

Pediatr Diabetes 2008 Jul;9(4 Pt 1):263-5

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http://dx.doi.org/10.1111/j.1399-5448.2008.00368.xDOI Listing
July 2008

Autologous umbilical cord blood infusion for type 1 diabetes.

Exp Hematol 2008 Jun 20;36(6):710-5. Epub 2008 Mar 20.

Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1016/j.exphem.2008.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2444031PMC
June 2008

Neonatal formula feeding leads to immunological alterations in an animal model of type 1 diabetes.

Pediatr Res 2008 Mar;63(3):303-7

Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida 32610, USA.

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http://dx.doi.org/10.1203/PDR.0b013e31815ed662DOI Listing
March 2008

Type 1 diabetes associated with acquired generalized lipodystrophy and insulin resistance: the effect of long-term leptin therapy.

J Clin Endocrinol Metab 2008 Jan 16;93(1):26-31. Epub 2007 Oct 16.

Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1210/jc.2007-1856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729152PMC
January 2008

Participant and parent experiences in the parenteral insulin arm of the diabetes prevention trial for type 1 diabetes.

Diabetes Care 2007 Sep 11;30(9):2193-8. Epub 2007 Jun 11.

Department of Medical Humanities and Social Sciences, Florida State College of Medicine, Tallahassee, Florida, USA.

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http://dx.doi.org/10.2337/dc06-2422DOI Listing
September 2007

Type 1 diabetes intervention trials 2007: where are we and where are we going?

Curr Opin Endocrinol Diabetes Obes 2007 Aug;14(4):283-7

Department of Pediatrics, University of Florida, Gainesville, Florida 32610, USA.

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http://dx.doi.org/10.1097/MED.0b013e32825a673bDOI Listing
August 2007

Endocrine complications of childhood cancer therapy: evaluation and management.

Pediatr Endocrinol Rev 2007 Mar;4(3):196-204

Department of Pediatrics, University of Florida School of Medicine, Gainesville, FL 32610, USA.

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March 2007

Maternal understanding of infant diabetes risk: differential effects of maternal anxiety and depression.

Genet Med 2006 Oct;8(10):665-70

Pediatric and Adolescent Unit, Genetics and Epidemiology Section, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.109701.gim.0000237794.24543.4dDOI Listing
October 2006

Islet cell autoantibodies: a case of a premature obituary.

Pediatr Diabetes 2005 Dec;6(4):181-3

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http://dx.doi.org/10.1111/j.1399-543X.2005.00128.xDOI Listing
December 2005

CD3-antibody therapy in new-onset type 1 diabetes mellitus.

N Engl J Med 2005 Nov;353(19):2086-7; author reply 2086-7

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http://dx.doi.org/10.1056/NEJM200511103531920DOI Listing
November 2005

Depressive symptoms in mothers of infants identified as genetically at risk for type 1 diabetes.

Diabetes Care 2005 Aug;28(8):1898-903

Pediatric & Adolescent Unit, Genetics and Epidemiology Section, Joslin Diabetes Center, One Joslin Place, Boston, MA 02115, USA.

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http://dx.doi.org/10.2337/diacare.28.8.1898DOI Listing
August 2005

Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes.

Diabetes 2005 May;54(5):1407-14

Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, ARB-R3-128, 1600 SW Archer Rd., Gainesville, FL 32610-0275, USA.

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http://diabetes.diabetesjournals.org/content/54/5/1407.full.
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http://dx.doi.org/10.2337/diabetes.54.5.1407DOI Listing
May 2005

Maternal efforts to prevent type 1 diabetes in at-risk children.

Diabetes Care 2005 Apr;28(4):916-21

Center for Biobehavioral Health, Columbus Children's Research Institute, 700 Children's Drive, Columbus, OH 43205, USA.

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http://dx.doi.org/10.2337/diacare.28.4.916DOI Listing
April 2005