Dermot Kenny

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Dermot Kenny

Publications by authors named "Dermot Kenny"

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65Publications

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Platelet activation, as measured by plasma soluble glycoprotein VI, is not associated with disease activity or ischaemic events in giant cell arteritis.

Ann Rheum Dis 2018 May 5. Epub 2018 May 5.

Department of Rheumatology, Mater Misericordiae University Hospital, Dublin Academic Medical Centre, Dublin, Ireland.

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May 2018

Better platelet function, less fibrinolysis and less hemolysis in re-transfused residual pump blood with the Ringer's chase technique - a randomized pilot study.

Perfusion 2018 04 27;33(3):185-193. Epub 2017 Sep 27.

6 Department of Cardio-Thoracic and Vascular Surgery and Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.

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April 2018

Increased platelet reactivity as measured by plasma glycoprotein VI in gout.

Platelets 2017 Nov 1:1-6. Epub 2017 Nov 1.

a Department of Rheumatology , Mater Misericordiae University Hospital, Dublin Academic Medical Centre , Dublin , Ireland.

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November 2017

Platelet behaviour on von Willebrand Factor changes in pregnancy: Consequences of haemodilution and intrinsic changes in platelet function.

Sci Rep 2017 Jul 25;7(1):6354. Epub 2017 Jul 25.

Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.

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July 2017

Increased soluble GPVI levels in cirrhosis: evidence for early in vivo platelet activation.

J Thromb Thrombolysis 2017 Jan;43(1):54-59

School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland.

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January 2017

Computational Tracking of Shear-Mediated Platelet Interactions with von Willebrand Factor.

Cardiovasc Eng Technol 2016 Dec 14;7(4):389-405. Epub 2016 Oct 14.

Irish Centre for High-End Computing, IT Building, National University of Ireland, University Road, Galway, Ireland.

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December 2016

Altered Platelet Function in Intrauterine Growth Restriction: A Cause or a Consequence of Uteroplacental Disease?

Am J Perinatol 2016 07 23;33(8):791-9. Epub 2016 Feb 23.

Department of Obstetrics and Gynecology, Royal College of Surgeons in Ireland, Rotunda Hospital, Dublin, Ireland.

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July 2016

Reduced spontaneous platelet aggregation: a novel risk factor for adverse pregnancy outcome.

Eur J Obstet Gynecol Reprod Biol 2016 Apr 20;199:132-6. Epub 2016 Feb 20.

Royal College of Surgeons in Ireland, Dept. of Obstetrics and Gynecology, Rotunda Hospital, Dublin, Ireland.

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April 2016

Self-Powered Microfluidic Device for Rapid Assay of Antiplatelet Drugs.

Langmuir 2016 Mar 8;32(11):2820-8. Epub 2016 Mar 8.

Biomedical Diagnostics Institute (BDI), Dublin City University , Dublin 9, Ireland.

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March 2016

Sulfasalazine and its metabolites inhibit platelet function in patients with inflammatory arthritis.

Clin Rheumatol 2016 Feb 26;35(2):447-55. Epub 2014 Sep 26.

Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, 123 St Stephen's Green, Dublin 2, Ireland.

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February 2016

Increased Thrombopoiesis and Platelet Activation in Hantavirus-Infected Patients.

J Infect Dis 2015 Oct 11;212(7):1061-9. Epub 2015 Mar 11.

Clinical Chemistry, Department of Medical Biosciences, Umeå University, Sweden.

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October 2015

Aspirin and P2Y12 inhibition attenuate platelet-induced ovarian cancer cell invasion.

BMC Cancer 2015 Sep 9;15:627. Epub 2015 Sep 9.

Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin 2, Ireland.

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September 2015

Age-related changes in platelet function are more profound in women than in men.

Sci Rep 2015 Jul 16;5:12235. Epub 2015 Jul 16.

1] Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland [2] Biomedical Diagnostics Institute, Dublin City University, Dublin, Ireland.

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July 2015

Examining platelet adhesion via Stokes flow simulations and microfluidic experiments.

Soft Matter 2015 Jan;11(2):355-67

Chemical Engineering, Stanford University, Stanford, CA, USA.

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January 2015

Platelet hyporeactivity in active myeloma.

Thromb Res 2014 Sep 5;134(3):747-9. Epub 2014 Jul 5.

Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin 2, Ireland. Electronic address:

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September 2014

Living in shear: platelets protect cancer cells from shear induced damage.

Clin Exp Metastasis 2014 Aug 19;31(6):697-704. Epub 2014 Jun 19.

Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin 2, Ireland.

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August 2014

Plasma fibrinogen along with patient-reported outcome measures enhances management of polymyalgia rheumatica: a prospective study.

J Rheumatol 2014 May 1;41(5):931-7. Epub 2014 Apr 1.

From the Department of Rheumatology, Mater Misericordiae University Hospital, Dublin; Department of Rheumatology, St. Vincents University Hospital, Dublin; and Department of Molecular and Cellular Therapeutics, Royal College of Surgeons, Dublin, Ireland.

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May 2014

Increased platelet reactivity in patients with late-stage metastatic cancer.

Cancer Med 2013 Aug 21;2(4):564-70. Epub 2013 May 21.

Molecular and Cellular Therapeutics, The Royal College of Surgeons in Ireland Dublin, Ireland ; The Biomedical Diagnostics Institute, Dublin City University Dublin, Ireland.

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August 2013

Plasma fibrinogen is an accurate marker of disease activity in patients with polymyalgia rheumatica.

Rheumatology (Oxford) 2013 Mar 3;52(3):465-71. Epub 2012 Nov 3.

Department of Rheumatology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.

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March 2013

Long-term follow-up of non-calcified pulmonary nodules (<10 mm) identified during low-dose CT screening for lung cancer.

Eur Radiol 2012 Sep 27;22(9):1923-8. Epub 2012 Apr 27.

Department of Radiology, Beaumont Hospital, Beaumont Road, Dublin, Ireland.

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September 2012

Cadherin 6 has a functional role in platelet aggregation and thrombus formation.

Arterioscler Thromb Vasc Biol 2012 Jul 26;32(7):1724-31. Epub 2012 Apr 26.

Royal College of Surgeons in Ireland, Dublin, Ireland.

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July 2012

Inhibition of platelet adhesion by peptidomimetics mimicking the interactive β-hairpin of glycoprotein Ibα.

Bioorg Med Chem Lett 2012 May 11;22(9):3323-6. Epub 2012 Mar 11.

Centre for Synthesis & Chemical Biology, Department of Pharmaceutical & Medicinal Chemistry, 123, St. Stephen's Green, Dublin 2, Ireland.

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May 2012

Effective hydrodynamic shaping of sample streams in a microfluidic parallel-plate flow-assay device: matching whole blood dynamic viscosity.

IEEE Trans Biomed Eng 2012 Feb 19;59(2):374-82. Epub 2011 Oct 19.

Biomedical Diagnostics Institute, Royal College of Surgeons in Ireland, Dublin 2, Ireland.

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February 2012

Platelet function testing: methods of assessment and clinical utility.

Cardiovasc Hematol Agents Med Chem 2011 Jan;9(1):14-24

Department of Cardiology, Beaumont Hospital, Dublin, Ireland.

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January 2011

New trends in bioanalytical microdevices to assess platelet function.

Expert Rev Mol Diagn 2010 Oct;10(7):869-74

Biomedical Diagnostics Institute, Dublin City University, Dublin, Ireland.

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October 2010

Platelet reactivity and pregnancy loss.

Am J Obstet Gynecol 2010 Sep 3;203(3):281.e1-5. Epub 2010 Aug 3.

Department of Obstetrics and Gynaecology, Royal College of Surgeons in Ireland, Dublin, Ireland.

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September 2010

Annexin V binding to platelets is agonist, time and temperature dependent.

Platelets 2010 ;21(4):289-96

Biomedical Diagnostics Institute Programme, Molecular & Cellular Therapeutics, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin 2, Ireland.

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August 2010

Evaluation of azithromycin, trovafloxacin and grepafloxacin as prophylaxis for experimental murine melioidosis.

Int J Antimicrob Agents 2010 Jul 11;36(1):87-9. Epub 2010 May 11.

Department of Biomedical Sciences, Defence Science and Technology Laboratory, Porton Down, Salisbury SP4 0JQ, UK.

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July 2010

Platelet hyper-reactivity in active inflammatory arthritis is unique to the adenosine diphosphate pathway: a novel finding and potential therapeutic target.

Rheumatology (Oxford) 2010 Feb 4;49(2):240-5. Epub 2009 Dec 4.

Department of Rheumatology, Mater Misericordiae University Hospital, RCSI, Dublin, Ireland.

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February 2010

Shear stress induces internalization of E-cadherin and invasiveness in metastatic oesophageal cancer cells by a Src-dependent pathway.

Cancer Sci 2009 Jun 16;100(6):1082-7. Epub 2009 Mar 16.

Molecular and Cellular Therapeutics, The Royal College of Surgeons in Ireland, Dublin, Ireland.

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June 2009

Myeloproliferative disorder therapy: assessment and management of adverse events--a cardiologist's perspective.

Authors:
Dermot Kenny

Hematol Oncol 2009 Jun;27 Suppl 1:8-10

Royal College of Surgeons in Ireland, Dublin, Ireland.

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June 2009

cDNA amplification by SMART-PCR and suppression subtractive hybridization (SSH)-PCR.

Methods Mol Biol 2009 ;496:223-43

Regenerative Medicine Institute, National University of Ireland, Galway, Ireland.

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December 2008

Platelet receptor redox regulation.

Platelets 2008 Feb;19(1):1-8

Department of Immunology, Monash University, Alfred Medical Research & Education Precinct, Melbourne 3004, Victoria, Australia.

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February 2008

S-Nitrosylation of platelet alphaIIbbeta3 as revealed by Raman spectroscopy.

Biochemistry 2007 May 3;46(21):6429-36. Epub 2007 May 3.

Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin 2, Ireland.

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May 2007

Bioinformatic discovery of novel bioactive peptides.

Nat Chem Biol 2007 Feb 14;3(2):108-12. Epub 2007 Jan 14.

Department of Clinical Pharmacology, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland.

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February 2007

Absolute net charge and the biological activity of oligopeptides.

J Chem Inf Model 2006 Sep-Oct;46(5):2183-90

UCD Conway Institute of Biomolecular and Biomedical Sciences, University College Dublin, Dublin 4, Republic of Ireland.

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November 2006

Mobility and invasiveness of metastatic esophageal cancer are potentiated by shear stress in a ROCK- and Ras-dependent manner.

Am J Physiol Cell Physiol 2006 Oct 26;291(4):C668-77. Epub 2006 Apr 26.

Department of Clinical Pharmacology, Royal College of Surgeons, Dublin, Ireland.

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October 2006

Pathogenesis of Yersinia pestis infection in BALB/c mice: effects on host macrophages and neutrophils.

Infect Immun 2005 Nov;73(11):7142-50

Department of Biomedical Sciences, Dstl Porton Down, Salisbury, Wiltshire, SP4 0JQ, United Kingdom.

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November 2005

Shear stress modulates the interaction of platelet-secreted matrix proteins with tumor cells through the integrin alphavbeta3.

Am J Physiol Cell Physiol 2004 Nov 7;287(5):C1320-7. Epub 2004 Jul 7.

Department of Clinical Pharmacology, The Royal College of Surgeons, Dublin 2, Ireland.

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November 2004

Platelet surface glycoprotein expression in post-stroke depression: a preliminary study.

Psychiatry Res 2003 May;118(2):175-81

Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin 2, Ireland.

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May 2003

Elevated expression of integrin alpha(IIb) beta(IIIa) in drug-naïve, first-episode schizophrenic patients.

Biol Psychiatry 2002 Nov;52(9):874-9

Respiratory Research Group, Smurfit Building, Beaumont Hospital, Beaumont, Ireland.

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November 2002

The cysteine knot of platelet glycoprotein Ib beta (GPIb beta) is critical for the interaction of GPIb beta with GPIX.

Blood 2002 Jun;99(12):4428-33

Blood Research Institute, the Blood Center of Southeastern Wisconsin, Milwaukee, 53226-0509, USA.

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June 2002

Depression is associated with an increase in the expression of the platelet adhesion receptor glycoprotein Ib.

Life Sci 2002 May;70(26):3155-65

Department of Psychiatry, Royal College of Surgeons in Ireland, 123 St Stephen's Green, 2, Dublin, Ireland.

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May 2002

Hereditary hemochromatosis: a common, often unrecognized, genetic disease.

Cleve Clin J Med 2002 Mar;69(3):224-6, 229-30, 232-3 passim

Department of Medicine, University College and Mater Misericordiae Hospital, Royal College of Surgeons in Ireland, Dublin.

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March 2002

Platelet glycoprotein Ib alpha receptor polymorphisms and recurrent ischaemic events in acute coronary syndrome patients.

J Thromb Thrombolysis 2002 Feb;13(1):13-9

Department of Clinical Pharmacology, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland.

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February 2002