Derek P Jewell

Derek P Jewell

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Derek P Jewell

Derek P Jewell

Publications by authors named "Derek P Jewell"

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The IL-23/IL-17 pathway in inflammatory bowel disease.

Expert Rev Gastroenterol Hepatol 2012 Apr;6(2):223-37

Translational Gastroenterology Unit, Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK.

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http://www.tandfonline.com/doi/full/10.1586/egh.11.107
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http://dx.doi.org/10.1586/egh.11.107DOI Listing
April 2012

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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http://dx.doi.org/10.1038/nature08979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892339PMC
April 2010

Contribution of histological, serological, and genetic factors to the clinical heterogeneity of adult-onset coeliac disease.

Scand J Gastroenterol 2009 ;44(9):1076-83

Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1080/00365520903100473DOI Listing
February 2010

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

Nat Genet 2009 Dec 15;41(12):1330-4. Epub 2009 Nov 15.

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http://dx.doi.org/10.1038/ng.483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812019PMC
December 2009

Association between genetic variants in myosin IXB and Crohn's disease.

Inflamm Bowel Dis 2009 Jul;15(7):1014-21

Wellcome Trust Centre of Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/ibd.20885DOI Listing
July 2009

Pneumococcal infection in patients with coeliac disease.

Eur J Gastroenterol Hepatol 2008 Jul;20(7):624-8

Gastroenterology Unit, Radcliffe Infirmary, Oxford, UK.

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http://dx.doi.org/10.1097/MEG.0b013e3282f45764DOI Listing
July 2008

Indeterminate colitis: a review of the concept--what's in a name?

Inflamm Bowel Dis 2008 Jun;14(6):850-7

Department of Pathology, University Hospital Leuven, Belgium.

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http://dx.doi.org/10.1002/ibd.20361DOI Listing
June 2008

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Authors:
Paul R Burton David G Clayton Lon R Cardon Nick Craddock Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem H Ouwehand Nilesh J Samani John A Todd Peter Donnelly Jeffrey C Barrett Dan Davison Doug Easton David M Evans Hin-Tak Leung Jonathan L Marchini Andrew P Morris Chris C A Spencer Martin D Tobin Antony P Attwood James P Boorman Barbara Cant Ursula Everson Judith M Hussey Jennifer D Jolley Alexandra S Knight Kerstin Koch Elizabeth Meech Sarah Nutland Christopher V Prowse Helen E Stevens Niall C Taylor Graham R Walters Neil M Walker Nicholas A Watkins Thilo Winzer Richard W Jones Wendy L McArdle Susan M Ring David P Strachan Marcus Pembrey Gerome Breen David St Clair Sian Caesar Katharine Gordon-Smith Lisa Jones Christine Fraser Elaine K Green Detelina Grozeva Marian L Hamshere Peter A Holmans Ian R Jones George Kirov Valentina Moskivina Ivan Nikolov Michael C O'Donovan Michael J Owen David A Collier Amanda Elkin Anne Farmer Richard Williamson Peter McGuffin Allan H Young I Nicol Ferrier Stephen G Ball Anthony J Balmforth Jennifer H Barrett Timothy D Bishop Mark M Iles Azhar Maqbool Nadira Yuldasheva Alistair S Hall Peter S Braund Richard J Dixon Massimo Mangino Suzanne Stevens John R Thompson Francesca Bredin Mark Tremelling Miles Parkes Hazel Drummond Charles W Lees Elaine R Nimmo Jack Satsangi Sheila A Fisher Alastair Forbes Cathryn M Lewis Clive M Onnie Natalie J Prescott Jeremy Sanderson Christopher G Matthew Jamie Barbour M Khalid Mohiuddin Catherine E Todhunter John C Mansfield Tariq Ahmad Fraser R Cummings Derek P Jewell John Webster Morris J Brown Mark G Lathrop John Connell Anna Dominiczak Carolina A Braga Marcano Beverley Burke Richard Dobson Johannie Gungadoo Kate L Lee Patricia B Munroe Stephen J Newhouse Abiodun Onipinla Chris Wallace Mingzhan Xue Mark Caulfield Martin Farrall Anne Barton Ian N Bruce Hannah Donovan Steve Eyre Paul D Gilbert Samantha L Hilder Anne M Hinks Sally L John Catherine Potter Alan J Silman Deborah P M Symmons Wendy Thomson Jane Worthington David B Dunger Barry Widmer Timothy M Frayling Rachel M Freathy Hana Lango John R B Perry Beverley M Shields Michael N Weedon Andrew T Hattersley Graham A Hitman Mark Walker Kate S Elliott Christopher J Groves Cecilia M Lindgren Nigel W Rayner Nicolas J Timpson Eleftheria Zeggini Melanie Newport Giorgio Sirugo Emily Lyons Fredrik Vannberg Adrian V S Hill Linda A Bradbury Claire Farrar Jennifer J Pointon Paul Wordsworth Matthew A Brown Jayne A Franklyn Joanne M Heward Matthew J Simmonds Stephen C L Gough Sheila Seal Michael R Stratton Nazneen Rahman Maria Ban An Goris Stephen J Sawcer Alastair Compston David Conway Muminatou Jallow Melanie Newport Giorgio Sirugo Kirk A Rockett Suzannah J Bumpstead Amy Chaney Kate Downes Mohammed J R Ghori Rhian Gwilliam Sarah E Hunt Michael Inouye Andrew Keniry Emma King Ralph McGinnis Simon Potter Rathi Ravindrarajah Pamela Whittaker Claire Widden David Withers Niall J Cardin Dan Davison Teresa Ferreira Joanne Pereira-Gale Ingeleif B Hallgrimsdo'ttir Bryan N Howie Zhan Su Yik Ying Teo Damjan Vukcevic David Bentley Matthew A Brown Alastair Compston Martin Farrall Alistair S Hall Andrew T Hattersley Adrian V S Hill Miles Parkes Marcus Pembrey Michael R Stratton Sarah L Mitchell Paul R Newby Oliver J Brand Jackie Carr-Smith Simon H S Pearce R McGinnis A Keniry P Deloukas John D Reveille Xiaodong Zhou Anne-Marie Sims Alison Dowling Jacqueline Taylor Tracy Doan John C Davis Laurie Savage Michael M Ward Thomas L Learch Michael H Weisman Mathew Brown

Nat Genet 2007 Nov 21;39(11):1329-37. Epub 2007 Oct 21.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

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http://dx.doi.org/10.1038/ng.2007.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680141PMC
November 2007

Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype.

Inflamm Bowel Dis 2007 Sep;13(9):1063-8

Wellcome Trust Centre for Human Genetics, University of Oxford, and Gastroenterology Unit, Gibson Laboratories, Radcliffe Infirmary, Oxford, UK.

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http://dx.doi.org/10.1002/ibd.20180DOI Listing
September 2007

Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene.

Inflamm Bowel Dis 2007 Aug;13(8):941-6

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1002/ibd.20162DOI Listing
August 2007

Fistulating anal Crohn's disease: results of combined surgical and infliximab treatment.

Dis Colon Rectum 2006 Dec;49(12):1837-41

Department of Colorectal Surgery, John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom.

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http://dx.doi.org/10.1007/s10350-006-0656-5DOI Listing
December 2006

TUCAN (CARD8) genetic variants and inflammatory bowel disease.

Gastroenterology 2006 Oct 5;131(4):1190-6. Epub 2006 Aug 5.

Wellcome Trust Centre for Human Genetics, University of Oxford, Drive, Headington, Oxford OX3 7BN, England, UK.

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http://dx.doi.org/10.1053/j.gastro.2006.08.008DOI Listing
October 2006

Therapy Insight: pyoderma gangrenosum-old disease, new management.

Nat Clin Pract Gastroenterol Hepatol 2005 Dec;2(12):587-94

Pharmacy Department, John Radcliffe Hospital, Headington, Oxford, UK.

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http://dx.doi.org/10.1038/ncpgasthep0339DOI Listing
December 2005

The pharmacogenetics of methotrexate in inflammatory bowel disease.

Pharmacogenet Genomics 2005 Oct;15(10):705-11

Gastroenterology Unit, University of Oxford, Gibson Laboratories, Radcliffe Infirmary, Oxford, UK.

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http://dx.doi.org/10.1097/01.fpc.0000172242.19675.33DOI Listing
October 2005

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease.

Hum Mol Genet 2005 May 24;14(10):1245-50. Epub 2005 Mar 24.

Thw Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, UK.

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http://dx.doi.org/10.1093/hmg/ddi135DOI Listing
May 2005

Comparison between prospective and retrospective evaluation of Crohn's disease activity index.

Am J Gastroenterol 2005 May;100(5):1117-20

Department of Gastroenterology, John Radcliffe Hospital, Headley Way, Headington, Oxford, United Kingdom.

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http://dx.doi.org/10.1111/j.1572-0241.2005.30487.xDOI Listing
May 2005

A common CTLA4 haplotype associated with coeliac disease.

Eur J Hum Genet 2005 Apr;13(4):440-4

Department of Gastroenterology, Imperial College London, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1038/sj.ejhg.5201357DOI Listing
April 2005

Clinical implications of inflammatory bowel disease genetics on phenotype.

Inflamm Bowel Dis 2005 Jan;11(1):56-61

Gastroenterology Unit, University of Oxford, Gibson Laboratories Radcliffe Infirmary, Oxford, UK.

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http://dx.doi.org/10.1097/00054725-200501000-00008DOI Listing
January 2005

The contribution of HLA genes to IBD susceptibility and phenotype.

Best Pract Res Clin Gastroenterol 2004 Jun;18(3):577-96

Gastroenterology Unit, Gibson Laboratories, University of Oxford, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK.

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http://dx.doi.org/10.1016/j.bpg.2004.01.003DOI Listing
June 2004

Inflammatory bowel disease is linked to 19p13 and associated with ICAM-1.

Inflamm Bowel Dis 2004 May;10(3):173-81

Gastroenterology Unit, Gibson Laboratories, Radcliffe Infirmary, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1097/00054725-200405000-00001DOI Listing
May 2004

Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1.

J Hepatol 2004 Mar;40(3):375-9

Gastroenterology Unit, Gibson Laboratories, Nuffield Department of Medicine, University of Oxford, 2nd Floor, Radcliffe Infirmary, Oxford OX2 6HE, UK.

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http://dx.doi.org/10.1016/j.jhep.2003.11.009DOI Listing
March 2004

The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease-associated variants.

Hum Mol Genet 2003 Oct 19;12(20):2569-75. Epub 2003 Aug 19.

Wellcome Trust Centre for Human Genetics and Gastoenterology Unit, University of Oxford, UK.

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http://dx.doi.org/10.1093/hmg/ddg281DOI Listing
October 2003

Haplotype-specific linkage disequilibrium patterns define the genetic topography of the human MHC.

Hum Mol Genet 2003 Mar;12(6):647-56

Gastroenterology Unit, University of Oxford, Gibson Laboratories, Radcliffe Infirmary, Woodstock Road, Oxford, OX2 6HE, UK.

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March 2003

Uveitis and erythema nodosum in inflammatory bowel disease: clinical features and the role of HLA genes.

Gastroenterology 2002 Sep;123(3):714-8

Gastroenterology Unit, St. Mary's Hospital, London, England.

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http://dx.doi.org/10.1053/gast.2002.35396DOI Listing
September 2002

The molecular classification of the clinical manifestations of Crohn's disease.

Gastroenterology 2002 Apr;122(4):854-66

Gastroenterology Unit, University of Oxford, Gibson Laboratories, Radcliffe Infirmary, Oxford, United Kingdom.

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http://dx.doi.org/10.1053/gast.2002.32413DOI Listing
April 2002