Publications





Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy.
Cancer Discov 2015 Dec 29;5(12):1282-95. Epub 2015 Oct 29.
Division of Cancer Pathobiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Immunology Graduate Group, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Cell & Molecular Biology Graduate Group, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Department of Pathology & Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.


A LIN28B-RAN-AURKA Signaling Network Promotes Neuroblastoma Tumorigenesis.
Cancer Cell 2015 Nov 17;28(5):599-609. Epub 2015 Oct 17.
Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus.
Cancer Res 2015 Aug 22;75(15):3155-66. Epub 2015 Jun 22.
Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania. The Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.


Rare variants in TP53 and susceptibility to neuroblastoma.
J Natl Cancer Inst 2014 Apr 14;106(4):dju047. Epub 2014 Mar 14.
Affiliations of authors: Division of Oncology (SJD, MDi, DAO, KC, KRB, MRR, JMM), Center for Childhood Cancer Research (SJD, MDi, DAO, KC, KRB, MRR, JMM), Center for Applied Genomics (HH), and Division of Genetics (HH, MDe) Children's Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics (SJD, DAO, KRB, HH, MDe, JMM), Abramson Cancer Center (SJD, JMM), Genomics and Computational Biology, Biomedical Graduate Studies (SJD, DAO, JMM), and Department of Biostatistics and Epidemiology (MDe), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA (SJD, HH, MDe, JMM); Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Naples, Italy (MC, AI); Ceinge-Biotecnologie Avanzate, Naples, Italy (MC, AI); University of Rome "La Sapienza," Department of Molecular Medicine, Rome, Italy (MDe).



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