Derek Leroith

Derek Leroith

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Derek Leroith

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Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool.

Cell 2019 Aug;178(5):1102-1114.e17

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA; The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.07.050DOI Listing
August 2019

Hyperinsulinemia promotes aberrant histone acetylation in triple-negative breast cancer.

Epigenetics Chromatin 2019 Jul 17;12(1):44. Epub 2019 Jul 17.

Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, CA, 91010, USA.

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http://dx.doi.org/10.1186/s13072-019-0290-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636093PMC
July 2019

Loss of Adipose Growth Hormone Receptor in Mice Enhances Local Fatty Acid Trapping and Impairs Brown Adipose Tissue Thermogenesis.

iScience 2019 Jun 16;16:106-121. Epub 2019 May 16.

Institute for Genome Engineered Animal Models of Human Diseases, Dalian Medical University, Dalian 116044, China; National Center of Genetically Engineered Animal Models for International Research, Dalian Medical University, Dalian 116044, China; Liaoning Provence Key Lab of Genome Engineered Animal Models, Dalian Medical University, Dalian 116044, China; College of Integrative Medicine, Dalian Medical University, Dalian 116044, China; Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Icahn Mount Sinai School of Medicine, New York 10029, USA; Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York 10010, USA. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545351PMC
June 2019

A Message from the Editor-in-Chief.

Authors:
Derek LeRoith

Endocr Pract 2019 Jan;25(1)

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http://dx.doi.org/10.4158/1934-2403-25.1.5DOI Listing
January 2019

Diabetes, Obesity, and Breast Cancer.

Endocrinology 2018 11;159(11):3801-3812

Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1210/en.2018-00574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202853PMC
November 2018

Insulin-like growth factor receptor signaling in breast tumor epithelium protects cells from endoplasmic reticulum stress and regulates the tumor microenvironment.

Breast Cancer Res 2018 11 20;20(1):138. Epub 2018 Nov 20.

Department of Pharmacology, Physiology & Neuroscience, Rutgers-New Jersey Medical School, Cancer Institute of New Jersey, Newark, NJ, 07101, USA.

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http://dx.doi.org/10.1186/s13058-018-1063-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245538PMC
November 2018

World leaders describe the latest in IGF research.

J Mol Endocrinol 2018 07;61(1):E1-E3

Endocrinology, Diabetes and Bone Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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http://dx.doi.org/10.1530/JME-18-0106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555139PMC
July 2018

Statin Use and Breast Cancer Prognosis in Black and White Women.

Horm Cancer 2018 02 19;9(1):55-61. Epub 2017 Oct 19.

Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://link.springer.com/10.1007/s12672-017-0312-7
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http://dx.doi.org/10.1007/s12672-017-0312-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873288PMC
February 2018

Synthesis: Deriving a Core Set of Recommendations to Optimize Diabetes Care on a Global Scale.

Ann Glob Health 2015 Nov-Dec;81(6):874-83

Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1016/j.aogh.2016.02.008DOI Listing
January 2018

Long-term treatment with the ghrelin receptor antagonist [d-Lys3]-GHRP-6 does not improve glucose homeostasis in nonobese diabetic MKR mice.

Am J Physiol Regul Integr Comp Physiol 2018 01 13;314(1):R71-R83. Epub 2017 Sep 13.

School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, Australia.

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http://dx.doi.org/10.1152/ajpregu.00157.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866362PMC
January 2018

A MESSAGE FROM THE EDITOR-IN-CHIEF.

Authors:
Derek LeRoith

Endocr Pract 2018 Jan;24(1)

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http://dx.doi.org/10.4158/1934-2403-24.1.5DOI Listing
January 2018

Lower mitochondrial DNA and altered mitochondrial fuel metabolism in HIV-exposed uninfected infants in Cameroon.

AIDS 2017 11;31(18):2475-2481

aDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York bDepartment of Pediatrics and Internal Medicine, Massachusetts General Hospital cDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts dDepartment of Medical Genetics, University of Mississippi Medical Center, Jackson, Mississippi, USA eCameroon Baptist Convention Health Services, Bamenda, Cameroon fICAP, Mailman School of Public Health and College of Physicians and Surgeons, Columbia University gDepartment of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, New York hKeck School of Medicine of USC, The Saban Research Institute of Children's Hospital Los Angeles, Los Angeles, California iDepartment of Medicine, Stable Isotope and Metabolomics Core Facility, Albert Einstein College of Medicine, Bronx, New York, USA jDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/QAD.0000000000001647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680102PMC
November 2017

THE INTERPLAY BETWEEN ENDOCRINOLOGY AND ONCOLOGY: THE NEW ROLE OF THE ENDOCRINOLOGIST.

Endocr Pract 2017 10 17;23(10):1167-1168. Epub 2017 Aug 17.

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http://dx.doi.org/10.4158/EP171997.EDDOI Listing
October 2017

OP449 inhibits breast cancer growth without adverse metabolic effects.

Endocr Relat Cancer 2017 10;24(10):519-529

Division of EndocrinologyDiabetes and Bone Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA

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http://dx.doi.org/10.1530/ERC-17-0077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678946PMC
October 2017

Activating Transcription Factor-5 Knockdown Reduces Aggressiveness of Mammary Tumor Cells and Attenuates Mammary Tumor Growth.

Front Endocrinol (Lausanne) 2017 21;8:173. Epub 2017 Jul 21.

Clinical Research Institute at Rambam (CRIR), Diabetes and Metabolism Clinical Research Center of Excellence, Rambam Medical Center, Haifa, Israel.

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http://dx.doi.org/10.3389/fendo.2017.00173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519529PMC
July 2017

Erratum to: Non-metabolisable insulin glargine does not promote breast cancer growth in a mouse model of type 2 diabetes.

Diabetologia 2017 04;60(4):758-759

Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1055, New York, NY, 10029, USA.

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http://dx.doi.org/10.1007/s00125-017-4225-3DOI Listing
April 2017

A Message from the Editor-in-Chief.

Authors:
Derek LeRoith

Endocr Pract 2017 01;23(1)

Editor-in-Chief, AACE Journals.

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http://journals.aace.com/doi/10.4158/1934-2403-23.1.4
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http://dx.doi.org/10.4158/1934-2403-23.1.4DOI Listing
January 2017

Type 2 Diabetes Mellitus and Cancer: The Role of Pharmacotherapy.

J Clin Oncol 2016 12 7;34(35):4261-4269. Epub 2016 Nov 7.

Gadi Shlomai, Brian Neel, Derek LeRoith, and Emily Jane Gallagher, Icahn School of Medicine at Mount Sinai, New York, NY; and Gadi Shlomai, The Chaim Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel.

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http://dx.doi.org/10.1200/JCO.2016.67.4044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455318PMC
December 2016

Metabolic syndrome and pre-diabetes contribute to racial disparities in breast cancer outcomes: hypothesis and proposed pathways.

Diabetes Metab Res Rev 2016 10 21;32(7):745-753. Epub 2016 Apr 21.

Icahn School of Medicine at Mount Sinai, Department of Population Health Science and Policy, Department of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1002/dmrr.2795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991957PMC
October 2016

Prediabetes and diabetes among HIV-infected adults in Cameroon.

Diabetes Metab Res Rev 2016 09 6;32(6):544-9. Epub 2016 Apr 6.

Department of Medicine, Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087795PMC
http://dx.doi.org/10.1002/dmrr.2792DOI Listing
September 2016

Non-metabolisable insulin glargine does not promote breast cancer growth in a mouse model of type 2 diabetes.

Diabetologia 2016 09 30;59(9):2018-25. Epub 2016 May 30.

Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1055, New York, NY, 10029, USA.

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http://dx.doi.org/10.1007/s00125-016-4000-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970885PMC
September 2016

EMT reversal in human cancer cells after IR knockdown in hyperinsulinemic mice.

Endocr Relat Cancer 2016 09 19;23(9):747-58. Epub 2016 Jul 19.

Division of EndocrinologyDiabetes and Bone Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA

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http://dx.doi.org/10.1530/ERC-16-0142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990486PMC
September 2016

Waist circumference is correlated with poorer cognition in elderly type 2 diabetes women.

Alzheimers Dement 2016 08 2;12(8):925-9. Epub 2016 May 2.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA; The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat Gan, Israel.

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http://dx.doi.org/10.1016/j.jalz.2016.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753411PMC
August 2016

Polyol accumulation in muscle and liver in a mouse model of type 2 diabetes.

J Diabetes Complications 2016 08 27;30(6):999-1007. Epub 2016 Apr 27.

Biotechnology Core Laboratory, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bldg 14A, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1016/j.jdiacomp.2016.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949127PMC
August 2016

Anti-inflammatory Agents in the Treatment of Diabetes and Its Vascular Complications.

Diabetes Care 2016 Aug;39 Suppl 2:S244-52

Diabetes Unit, Hadassah University Hospital, Jerusalem, Israel Endocrine Service, Hadassah University Hospital, Jerusalem, Israel

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http://dx.doi.org/10.2337/dcS15-3015DOI Listing
August 2016

Insulin-like Growth Factor 1 Signaling Axis Meets p53 Genome Protection Pathways.

Front Oncol 2016 23;6:159. Epub 2016 Jun 23.

Department of Obstetrics and Gynecology, Hillel Yaffe Medical Center , Hadera , Israel.

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http://dx.doi.org/10.3389/fonc.2016.00159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917523PMC
July 2016

Metabolic Syndrome, Type 2 Diabetes, and Cancer: Epidemiology and Potential Mechanisms.

Handb Exp Pharmacol 2016 ;233:355-72

Clinical Research Institute at Rambam (CRIR), Diabetes and Metabolism Clinical Research Center of Excellence, Rambam Health Care Campus, Haifa, Israel.

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http://link.springer.com/content/pdf/10.1007%2F164_2015_12.p
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http://link.springer.com/10.1007/164_2015_12
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http://dx.doi.org/10.1007/164_2015_12DOI Listing
June 2016

CD24 cell surface expression in Mvt1 mammary cancer cells serves as a biomarker for sensitivity to anti-IGF1R therapy.

Breast Cancer Res 2016 05 14;18(1):51. Epub 2016 May 14.

Diabetes and Metabolism Clinical Research Center of Excellence, Clinical Research Institute at Rambam (CRIR), Rambam Medical Center, Haifa, Israel.

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http://dx.doi.org/10.1186/s13058-016-0711-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867988PMC
May 2016

Getting to the "Heart" of the Matter on Diabetic Cardiovascular Disease: "Thanks for the Memory".

Diabetes Care 2016 05;39(5):664-7

Division of Endocrinology, Diabetes and Clinical Nutrition, Oregon Health & Science University, Portland, OR.

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http://dx.doi.org/10.2337/dc16-0405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013718PMC
May 2016

Ovariectomy is associated with metabolic impairments and enhanced mammary tumor growth in MKR mice.

J Endocrinol 2015 Dec 17;227(3):143-151. Epub 2015 Sep 17.

Diabetes and Metabolism Clinical Research Center of Excellence, Clinical Reseasch Institute at Rambam (CRIR), Rambam Medical Center, P.O.B 9602, Haifa 31096, Israel.

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http://joe.endocrinology-journals.org/content/227/3/143.full
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http://joe.endocrinology-journals.org/lookup/doi/10.1530/JOE
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http://dx.doi.org/10.1530/JOE-15-0310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618719PMC
December 2015

Reproductive Endocrinology.

Authors:
Derek LeRoith

Endocrinol Metab Clin North Am 2015 Dec;44(4):xiii-xv

Division of Endocrinology, Diabetes and Bone Diseases, Icahn School of Medicine at Mt Sinai, 1 Gustave Levy Place (1055), Atran B4-35, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2015.09.015DOI Listing
December 2015

Insulin's Role in Diabetes Management: After 90 Years, Still Considered the Essential "Black Dress".

Diabetes Care 2015 Dec;38(12):2200-3

Division of Endocrinology, Diabetes & Clinical Nutrition, Oregon Health & Science University, Portland, OR.

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http://dx.doi.org/10.2337/dci15-0023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657614PMC
December 2015

Multi-tissue computational modeling analyzes pathophysiology of type 2 diabetes in MKR mice.

PLoS One 2014 16;9(7):e102319. Epub 2014 Jul 16.

Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102319PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100879PMC
November 2015

Shorter adult height is associated with poorer cognitive performance in elderly men with type II diabetes.

J Alzheimers Dis 2015 ;44(3):927-35

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat Gan, Israel.

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http://dx.doi.org/10.3233/JAD-142049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753414PMC
October 2015

Glycemic control, inflammation, and cognitive function in older patients with type 2 diabetes.

Int J Geriatr Psychiatry 2015 Oct 20;30(10):1093-100. Epub 2015 Feb 20.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1002/gps.4267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753409PMC
October 2015

Lower Preprandial Insulin and Altered Fuel Use in HIV/Antiretroviral-Exposed Infants in Cameroon.

J Clin Endocrinol Metab 2015 Sep 2;100(9):3260-9. Epub 2015 Jul 2.

Departments of Medicine (J.J.), Obstetrics, Gynecology, and Reproductive Science (J.J.), Genetics and Genomic Sciences (C.Y.), and Obstetrics, Gynecology, and Reproductive Science (R.S.S.), and Department of Medicine (D.L.), Division of Endocrinology, Icahn School of Medicine, Mt Sinai, New York, New York 10029; Department of Pediatrics (B.K.), Division of Genetics and Metabolism, Children's National Medical Center/George Washington University School of Medicine, Washington, DC 20037; Department of Medicine (Y.Q., I.J.K.), Division of Endocrinology, Albert Einstein College of Medicine, Bronx, New York 10461; Departments of Pediatrics and Internal Medicine (K.P.), Massachusetts General Hospital, Boston, Massachusetts 02114; Cameroon Baptist Convention Health Services (E.N., F.E., P.M.T.), Bamenda, Cameroon; ICAP (E.J.A.), Mailman School of Public Health and College of Physicians and Surgeons, Columbia University, New York, New York 10032; and The Saban Research Institute of Children's Hospital Los Angeles (M.E.G.), Keck School of Medicine of University of Southern California, Los Angeles, California 90033.

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http://dx.doi.org/10.1210/JC.2015-2198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570172PMC
September 2015

Postmenopausal Endocrinology. Foreword.

Authors:
Derek LeRoith

Endocrinol Metab Clin North Am 2015 Sep 14;44(3):xiii-xv. Epub 2015 Jul 14.

Director of Research, Division of Endocrinology, Diabetes and Bone Diseases, Icahn School of Medicine at Mt Sinai, 1 Gustave Levy Place (1055), Atran B4-35, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2015.07.002DOI Listing
September 2015

Deep sequencing of mRNA in CD24(-) and CD24(+) mammary carcinoma Mvt1 cell line.

Genom Data 2015 Sep 9;5:399-401. Epub 2015 Jul 9.

Departments of Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, NY 10029, United States.

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http://dx.doi.org/10.1016/j.gdata.2015.06.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583690PMC
September 2015

microRNAs: what the clinician should know about this new frontier.

Authors:
Derek Leroith

Diabetes Care 2014 ;37(5):1176-7

Corresponding author: Derek LeRoith,

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http://dx.doi.org/10.2337/dc13-3050DOI Listing
August 2015

The beneficial effect of growth hormone treatment on islet mass in streptozotocin-treated mice.

Diabetes Metab Res Rev 2015 Jul 6;31(5):492-9. Epub 2015 Feb 6.

The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

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http://dx.doi.org/10.1002/dmrr.2631DOI Listing
July 2015

Adrenal cortical neoplasia.

Authors:
Derek LeRoith

Endocrinol Metab Clin North Am 2015 Jun;44(2):xiii-xv

Division of Endocrinology, Diabetes and Bone Diseases, Icahn School of Medicine at Mount Sinai, 1 Gustave Levy Place (1055), Atran B4-35, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2015.03.003DOI Listing
June 2015

CD24(+) cells fuel rapid tumor growth and display high metastatic capacity.

Breast Cancer Res 2015 Jun 4;17:78. Epub 2015 Jun 4.

Diabetes and Metabolism Clinical Research Center of Excellence, Clinical Research Institute at Rambam (CRIR) and the Faculty of Medicine, Technion, Rambam Medical Center, P.O.B 9602, Haifa, 31096, Israel.

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http://dx.doi.org/10.1186/s13058-015-0589-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479226PMC
June 2015

Highly specific role of the insulin receptor in breast cancer progression.

Endocr Relat Cancer 2015 Apr;22(2):145-57

Clinical Research Institute at Rambam (CRIR) and the Faculty of MedicineTechnion, Diabetes and Metabolism Clinical Research Center of Excellence, Haifa, IsraelThe Laboratory of Molecular MedicineRambam Health Care Campus and Rappaport Faculty of Medicine and Research Institute, Technion, Haifa 31096, IsraelDivision of EndocrinologyDiabetes and Bone Diseases, Icahn School of Medicine at Mount Sinai, New York City, New York, USA Clinical Research Institute at Rambam (CRIR) and the Faculty of MedicineTechnion, Diabetes and Metabolism Clinical Research Center of Excellence, Haifa, IsraelThe Laboratory of Molecular MedicineRambam Health Care Campus and Rappaport Faculty of Medicine and Research Institute, Technion, Haifa 31096, IsraelDivision of EndocrinologyDiabetes and Bone Diseases, Icahn School of Medicine at Mount Sinai, New York City, New York, USA

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http://dx.doi.org/10.1530/ERC-14-0490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362669PMC
April 2015

Pituitary disorders.

Authors:
Derek LeRoith

Endocrinol Metab Clin North Am 2015 Mar 15;44(1):xvii-xx. Epub 2014 Dec 15.

Director of Research, Division of Endocrinology, Metabolism, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1055, Altran 4-36, New York, NY 10024, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2014.12.002DOI Listing
March 2015

Insulin and insulin-like growth factor receptors in the brain: physiological and pathological aspects.

Eur Neuropsychopharmacol 2014 Dec 31;24(12):1947-53. Epub 2014 Jan 31.

Diabetes and Metabolism Clinical Research Center of Excellence, Clinical Research Institute at Rambam (LHCRIR), Rambam-Health Care Campus, P.O. Box 9602, Haifa 31096, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2014.01.020DOI Listing
December 2014

Lipids 2014: new guidelines, new concepts, new diets, new drugs.

Authors:
Derek LeRoith

Endocrinol Metab Clin North Am 2014 Dec 11;43(4):ix-xi. Epub 2014 Oct 11.

Division of Endocrinology, Metabolism, and Bone Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1055, Altran 4-36, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2014.09.002DOI Listing
December 2014

Growth hormone receptor signaling is dispensable for HSC function and aging.

Blood 2014 Nov 1;124(20):3076-80. Epub 2014 Oct 1.

Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA; Department of Stem Cell and Regenerative Medicine, Harvard University, Cambridge, MA; and.

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http://www.bloodjournal.org/content/early/2014/10/01/blood-2
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http://www.bloodjournal.org/content/124/20/3076.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-05-57
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http://dx.doi.org/10.1182/blood-2014-05-575308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231418PMC
November 2014

The association of duration of type 2 diabetes with cognitive performance is modulated by long-term glycemic control.

Am J Geriatr Psychiatry 2014 Oct 23;22(10):1055-9. Epub 2014 Jan 23.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY; The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat Gan, Israel; Maccabi Healthcare Services, Tel-Aviv, Israel.

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http://dx.doi.org/10.1016/j.jagp.2014.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108577PMC
October 2014

IGF1R inhibition in mammary epithelia promotes canonical Wnt signaling and Wnt1-driven tumors.

Cancer Res 2014 Oct 4;74(19):5668-79. Epub 2014 Aug 4.

Department of Neurology and Neuroscience, New Jersey Medical School Cancer Center, Rutgers Biomedical and Health Sciences, Newark, New Jersey.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782979PMC
October 2014

Endocrinology and Metabolism Clinics of North America. HIV and endocrine disorders. Foreword.

Authors:
Derek LeRoith

Endocrinol Metab Clin North Am 2014 Sep;43(3):xiii-xv

Director of Research, Division of Endocrinology, Metabolism, and Bone Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1055, Altran 4-36, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2014.07.002DOI Listing
September 2014

Non-viability of crossing the Alzheimer mouse model Tg2576 with the type 2 diabetes mouse model ob/ob.

Neurobiol Aging 2014 Jul 31;35(7):e19-20. Epub 2014 Jan 31.

The Sheba Medical Center, The Joseph Sagol Neuroscience Center, Ramat Gan, Israel; Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.01.138DOI Listing
July 2014

Insulin therapy in people with type 2 diabetes: opportunities and challenges?

Diabetes Care 2014 Jun;37(6):1499-508

Diabetes Unit, Department of Internal Medicine, Hadassah Hebrew University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.2337/dc13-2743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131884PMC
June 2014

Thyroid cancer and other thyroid disorders.

Authors:
Derek LeRoith

Endocrinol Metab Clin North Am 2014 Jun 4;43(2):xiii-xvi. Epub 2014 Apr 4.

Division of Endocrinology, Metabolism, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1055, Altran 4-36, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2014.03.001DOI Listing
June 2014

Diabetic nephropathy in a nonobese mouse model of type 2 diabetes mellitus.

Am J Physiol Renal Physiol 2014 May 5;306(9):F1008-17. Epub 2014 Mar 5.

Dept. of Medicine/Nephrology, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1243, New York, NY.

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http://dx.doi.org/10.1152/ajprenal.00597.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010680PMC
May 2014

The effect of dipeptidyl peptidase-IV inhibition on bone in a mouse model of type 2 diabetes.

Diabetes Metab Res Rev 2014 Mar;30(3):191-200

Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1002/dmrr.2466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496098PMC
March 2014

Diabetes mellitus: associated conditions. Foreword.

Authors:
Derek LeRoith

Endocrinol Metab Clin North Am 2014 Mar 2;43(1):xiii-xvi. Epub 2013 Dec 2.

Division of Endocrinology, Metabolism, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1055, Altran 4-36, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2013.10.004DOI Listing
March 2014

The epidemiology and molecular mechanisms linking obesity, diabetes, and cancer.

Vitam Horm 2013 ;93:51-98

Division of Endocrinology, Diabetes and Bone Diseases, Samuel Bronfman Department of Medicine, Mount Sinai School of Medicine, P.O. Box 1055, New York, USA.

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http://dx.doi.org/10.1016/B978-0-12-416673-8.00010-1DOI Listing
December 2013

Insulin and IGFs in obesity-related breast cancer.

J Mammary Gland Biol Neoplasia 2013 Dec 24;18(3-4):277-89. Epub 2013 Oct 24.

Department of Endocrinology, University of Pisa, Via Paradisa 2, 50124, Pisa, Italy.

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http://dx.doi.org/10.1007/s10911-013-9303-7DOI Listing
December 2013

Endocrinology and Metabolism Clinics of North America. Acute and chronic complications of diabetes. Foreword.

Authors:
Derek LeRoith

Endocrinol Metab Clin North Am 2013 Dec 1;42(4):xiii-xv. Epub 2013 Aug 1.

Director of Research, Division of Endocrinology, Metabolism, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1055, Altran 4-36, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2013.07.008DOI Listing
December 2013

Insulin receptor phosphorylation by endogenous insulin or the insulin analog AspB10 promotes mammary tumor growth independent of the IGF-I receptor.

Diabetes 2013 Oct 8;62(10):3553-60. Epub 2013 Jul 8.

Division of Endocrinology, Diabetes and Bone Diseases, Samuel Bronfman Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.2337/db13-0249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781483PMC
October 2013

Deletion of growth hormone receptors in postnatal skeletal muscle of male mice does not alter muscle mass and response to pathological injury.

Endocrinology 2013 Oct 16;154(10):3776-83. Epub 2013 Jul 16.

MD, PhD, Division of Endocrinology, Metabolism, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1055, New York, New York 10029.

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http://dx.doi.org/10.1210/en.2013-1209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398538PMC
October 2013

Diabetes, antihyperglycemic medications and cancer risk: smoke or fire?

Curr Opin Endocrinol Diabetes Obes 2013 Oct;20(5):485-94

Department of Medicine, Division of Endocrinology, Mt Sinai School of Medicine, New York, New York 10029-6574, USA.

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http://dx.doi.org/10.1097/01.med.0000433065.16918.83DOI Listing
October 2013

Bidirectional impact of endocrine disorders.

Authors:
Derek LeRoith

Endocrinol Metab Clin North Am 2013 Sep 4;42(3):xiii-xv. Epub 2013 Jul 4.

Division of Endocrinology, Metabolism, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1055, Altran 4-36, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.ecl.2013.06.007DOI Listing
September 2013

Epidemiology and molecular mechanisms tying obesity, diabetes, and the metabolic syndrome with cancer.

Diabetes Care 2013 Aug;36 Suppl 2:S233-9

Division of Endocrinology, Diabetes and Bone Disease, Samuel Bronfman Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.2337/dcS13-2001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920794PMC
August 2013

Does a single nucleotide polymorphism in the FGFR explain the connection between diabetes and cancer?

Cell Metab 2013 Jun;17(6):808-9

Division of Endocrinology, Diabetes & Bone Disease and the Diabetes, Obesity, Metabolism Institute, Icahn School of Medicine at Sinai, 1 Gustave L. Levy Place, Atran 4th floor-36, Box 1055, New York, NY 10029-6574, USA.

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http://dx.doi.org/10.1016/j.cmet.2013.05.006DOI Listing
June 2013