Derek Jonker

Derek Jonker

UNVERIFIED PROFILE

Are you Derek Jonker?   Register this Author

Register author
Derek Jonker

Derek Jonker

Publications by authors named "Derek Jonker"

Are you Derek Jonker?   Register this Author

63Publications

1907Reads

50Profile Views

KRAS Status as a Predictor of Chemotherapy Activity in Patients With Metastatic Colorectal Cancer.

Clin Colorectal Cancer 2019 Dec 27;18(4):e309-e315. Epub 2019 Aug 27.

Ottawa Hospital Cancer Centre, Ottawa, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clcc.2019.05.004DOI Listing
December 2019

Combination of germline variations associated with survival of folinic acid, fluorouracil and irinotecan-treated metastatic colorectal cancer patients.

Pharmacogenomics 2019 11 8;20(17):1179-1187. Epub 2019 Nov 8.

Pharmacogenomics Laboratory, Centre Hospitalier Universitaire de Québec (CHU de Québec) Research Center & Faculty of Pharmacy, Laval University, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs-2019-0091DOI Listing
November 2019

Can Administrative Data Improve the Performance of Cancer Clinical Trial Economic Analyses?

J Oncol Pract 2019 Sep 15;15(9):e807-e824. Epub 2019 Jul 15.

Canadian Cancer Trials Group, Kingston, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JOP.18.00691DOI Listing
September 2019

Germline variability and tumor expression level of ribosomal protein gene RPL28 are associated with survival of metastatic colorectal cancer patients.

Sci Rep 2019 Sep 10;9(1):13008. Epub 2019 Sep 10.

Pharmacogenomics Laboratory, Centre Hospitalier Universitaire de Québec (CHU de Québec) Research Center - Laval University and Faculty of Pharmacy, Laval University, Québec, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-49477-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736932PMC
September 2019

Advantages of the net benefit regression framework for trial-based economic evaluations of cancer treatments: an example from the Canadian Cancer Trials Group CO.17 trial.

BMC Cancer 2019 Jun 7;19(1):552. Epub 2019 Jun 7.

Division of Health Policy and Management, Department of Public Health Sciences and Associate Director, Center for Healthcare Policy and Research, 2103 Stockton Blvd, Sacramento, CA, 95817, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-019-5779-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555934PMC
June 2019

Health related quality of life in older or frail patients with advanced colorectal cancer treated with dose reduced capecitabine.

J Geriatr Oncol 2018 11 2;9(6):659-664. Epub 2018 May 2.

London Regional Cancer Program, London, Ontario, Canada; Schulich School of Medicine and Dentistry, London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jgo.2018.04.002DOI Listing
November 2018

A Phase I Study of Irinotecan, Capecitabine (Xeloda), and Oxaliplatin in Patients With Advanced Colorectal Cancer.

Clin Colorectal Cancer 2018 06 15;17(2):e257-e268. Epub 2017 Dec 15.

Digestive Oncology Unit, Department of Gastroenterology, Universitair Ziekenhuis Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clcc.2017.12.003DOI Listing
June 2018

The Prognostic Significance of c-MET and EGFR Overexpression in Resected Gastric Adenocarcinomas.

Am J Clin Oncol 2017 Dec;40(6):543-551

Department of Pathology and Laboratory Medicine, Division of Anatomical Pathology, The Ottawa Hospital, University of Ottawa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/COC.0000000000000202DOI Listing
December 2017

PET imaging in anal canal cancer: a systematic review and meta-analysis.

Br J Radiol 2017 Dec 3;90(1080):20170370. Epub 2017 Oct 3.

3 Division of Medical Oncology, University of Ottawa, The Ottawa Hospital Cancer Centre, General Campus , Ottawa, ONT , Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1259/bjr.20170370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047643PMC
December 2017

Pretreatment Serum Folate Levels and Toxicity/Efficacy in Colorectal Cancer Patients Treated With 5-Fluorouracil and Folinic Acid.

Clin Colorectal Cancer 2016 12 23;15(4):369-376.e3. Epub 2016 Jun 23.

Division of Medical Oncology, Department of Oncology, London Health Sciences Centre and University of Western Ontario, London, Ontario, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clcc.2016.06.001DOI Listing
December 2016

Fc-γ Receptor Polymorphisms, Cetuximab Therapy, and Survival in the NCIC CTG CO.17 Trial of Colorectal Cancer.

Clin Cancer Res 2016 05;22(10):2435-44

Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, Australia. Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia. School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-15-0414DOI Listing
May 2016

ABCC5 and ABCG1 polymorphisms predict irinotecan-induced severe toxicity in metastatic colorectal cancer patients.

Pharmacogenet Genomics 2015 Dec;25(12):573-83

aPharmacogenomics Laboratory, Centre Hospitalier Universitaire de Québec (CHU de Québec) Research Center and Faculty of Pharmacy bCHU de Québec Research Center and Faculty of Medicine, Laval University cCanada Research Chair in Pharmacogenomics, CHU de Québec Research Center, Québec, Canada dDepartment of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada eDepartment of Molecular Biology and Translational Research, Division of Experimental and Clinical Pharmacology, National Cancer Institute and Cancer for Molecular Biomedicine, Aviano, Italy fEshelman School of Pharmacy, Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina, Chapel Hill, North Carolina, USA.

View Article

Download full-text PDF

Source
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/FPC.0000000000000168DOI Listing
December 2015

Patterns of recurrence following selective intraoperative radiofrequency ablation as an adjunct to hepatic resection for colorectal liver metastases.

J Surg Oncol 2014 Nov 25;110(6):734-8. Epub 2014 Jun 25.

Liver and Pancreas Unit, Department of Surgery, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jso.23689DOI Listing
November 2014

Role of fine-needle aspiration in the surgical management of pancreatic neuroendocrine tumors: utility and limitations in light of the new World Health Organization classification.

Arch Pathol Lab Med 2014 Jul;138(7):896-902

From the Departments of Pathology & Laboratory Medicine (Drs Moyana and Hakim) and Radiological Sciences (Dr Shabana) and the Divisions of Radiation Oncology (Drs Kendal and Grimard), Gastroenterology (Dr Chatterjee), Medical Oncology (Drs Maroun and Jonker), and Hepatobiliary Surgery (Dr Mimeault), The Ottawa Hospital and University of Ottawa, Ottawa, Ontario, Canada.

View Article

Download full-text PDF

Source
http://www.archivesofpathology.org/doi/abs/10.5858/arpa.2013
Publisher Site
http://dx.doi.org/10.5858/arpa.2013-0300-OADOI Listing
July 2014

Chemotherapy regimens for advanced pancreatic cancer: a systematic review and network meta-analysis.

BMC Cancer 2014 Jun 27;14:471. Epub 2014 Jun 27.

Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2407-14-471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097092PMC
June 2014

Thymic epithelial neoplasms: a 12-year Canadian regional cancer program experience.

Clin Lung Cancer 2014 May 27;15(3):231-6. Epub 2013 Dec 27.

Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Ontario, Canada; The Ottawa Hospital, Ottawa, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cllc.2013.12.003DOI Listing
May 2014

PIK3CA, BRAF, and PTEN status and benefit from cetuximab in the treatment of advanced colorectal cancer--results from NCIC CTG/AGITG CO.17.

Clin Cancer Res 2014 Feb 11;20(3):744-53. Epub 2013 Nov 11.

Authors' Affiliation: Flinders University, Flinders Centre for Innovation in Cancer; Department of Medical Oncology, Flinders Medical Centre, Flinders Drive, Bedford Park, South Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-13-0606DOI Listing
February 2014

Sunitinib combined with pemetrexed and carboplatin in patients with advanced solid malignancies--results of a phase I dose-escalation study.

Invest New Drugs 2013 Dec 22;31(6):1487-98. Epub 2013 Aug 22.

Centre de Lutte Contre le Cancer du CHUM - Hôpital Notre-Dame, 6ième étage (G6162), Pavillon Deschamps, 1560 Sherbrooke Est, Montréal, QC, H2L 4M1, Canada,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10637-013-0010-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825543PMC
December 2013

Phase I clinical trial of Exherin (ADH-1) in patients with advanced solid tumors.

Curr Clin Pharmacol 2013 Feb;8(1):81-8

Ottawa Hospital Cancer Centre, 501 Smyth Road, Ottawa, Ontario, Canada.

View Article

Download full-text PDF

Source
February 2013

Impact of patient selection, disease progression, and adverse events on esophageal cancer outcomes after trimodality therapy.

Ann Thorac Surg 2012 Nov 13;94(5):1659-66. Epub 2012 Sep 13.

Division of Thoracic Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S000349751201201
Publisher Site
http://dx.doi.org/10.1016/j.athoracsur.2012.05.044DOI Listing
November 2012

A phase I/II study of the Src inhibitor saracatinib (AZD0530) in combination with gemcitabine in advanced pancreatic cancer.

Invest New Drugs 2012 Apr 18;30(2):779-86. Epub 2010 Dec 18.

Division of Medical Oncology and Hematology, Rm 5-708, Princess Margaret Hospital, 610 University Avenue, Toronto M5G2M9, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10637-010-9611-3DOI Listing
April 2012

ADH-1 in the treatment of metastatic adrenocortical carcinoma--case report.

Anticancer Res 2011 Nov;31(11):3921-5

The Ottawa Hospital Cancer Centre, Ottawa, ON, Canada.

View Article

Download full-text PDF

Source
November 2011

The role of the epidermal growth factor receptor in the mechanism and treatment of colorectal cancer.

Discov Med 2011 Feb;11(57):95-105

Department of Medical Oncology, The Ottawa Hospital, Ottawa, Ontario, K1h 8L6, Canada.

View Article

Download full-text PDF

Source
February 2011

Optimized manual and automated recovery of amplifiable DNA from tissues preserved in buffered formalin and alcohol-based fixative.

Forensic Sci Int Genet 2010 Feb 8;4(2):80-8. Epub 2009 Jul 8.

Royal Canadian Mounted Police, National Services and Research, 1200 Vanier Parkway, Ottawa, Ontario K1A 0R2, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fsigen.2009.06.003DOI Listing
February 2010

Phase I study of cediranib in combination with oxaliplatin and infusional 5-Fluorouracil in patients with advanced colorectal cancer.

Clin Cancer Res 2009 Feb;15(4):1481-6

The National Cancer Institute of Canada, Clinical Trials Group, Kingston, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-08-0761DOI Listing
February 2009

Acute proctocolitis with commencement of neoadjuvant chemoradiation for rectal cancer.

Am J Clin Oncol 2006 Oct;29(5):534-5

The Ottawa Hospital Regional Cancer Centre and The Ottawa Hospital, Ottawa, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.coc.0000175290.65929.3bDOI Listing
October 2006

Nuclear expression of thymidylate synthase in colorectal cancer cell lines and clinical samples.

J Histochem Cytochem 2006 Jan 13;54(1):19-29. Epub 2005 Jun 13.

Ottawa Regional Cancer Centre, 503 Smyth Road, Ottawa, Ontario, Canada K1H 1C4.

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1369/jhc.5A6642.2005
Publisher Site
http://dx.doi.org/10.1369/jhc.5A6642.2005DOI Listing
January 2006

A prospective clinical trial of green tea for hormone refractory prostate cancer: an evaluation of the complementary/alternative therapy approach.

Urol Oncol 2005 Mar-Apr;23(2):108-13

Division of Radiation Oncology, The Ottawa Hospital Regional Cancer Centre, Ottawa, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urolonc.2004.10.008DOI Listing
September 2005

A 3-week gemcitabine-cisplatin regimen for metastatic urothelial cancer.

Can J Urol 2004 Dec;11(6):2445-9

London Health Sciences Centre, London, Ontario, Canada.

View Article

Download full-text PDF

Source
December 2004