Publications by authors named "Derek Chiang"

49Publications

Elucidating therapeutic molecular targets in premenopausal Asian women with recurrent breast cancers.

NPJ Breast Cancer 2018 26;4:19. Epub 2018 Jul 26.

3Oncology Next-Generation Diagnostics, Novartis Institutes for Biomedical Research, Cambridge, USA.

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http://dx.doi.org/10.1038/s41523-018-0070-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062514PMC
July 2018

Progress towards molecular patient stratification of hepatocellular carcinoma: Lost in translation?

J Hepatol 2017 11 31;67(5):893-895. Epub 2017 Aug 31.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Division of Hematology and Medical Oncology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.07.031DOI Listing
November 2017

Integrative biomarker analyses indicate etiological variations in hepatocellular carcinoma.

J Hepatol 2016 08 27;65(2):296-304. Epub 2016 Apr 27.

Novartis Institutes for Biomedical Research, Cambridge, MA, USA.

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http://dx.doi.org/10.1016/j.jhep.2016.04.015DOI Listing
August 2016

Mutations of isocitrate dehydrogenase 1 and 2 in intrahepatic cholangiocarcinoma.

Curr Opin Gastroenterol 2014 May;30(3):295-302

Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MOG.0000000000000050DOI Listing
May 2014

A robust method for transcript quantification with RNA-seq data.

J Comput Biol 2013 Mar;20(3):167-87

Department of Computer Science, University of Kentucky , Lexington, KY 40506, USA.

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http://dx.doi.org/10.1089/cmb.2012.0230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590898PMC
March 2013

iReckon: simultaneous isoform discovery and abundance estimation from RNA-seq data.

Genome Res 2013 Mar 29;23(3):519-29. Epub 2012 Nov 29.

Department of Computer Science, University of Toronto, Ontario M5S 2E4, Canada.

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http://dx.doi.org/10.1101/gr.142232.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589540PMC
March 2013

Integrating prior knowledge in multiple testing under dependence with applications to detecting differential DNA methylation.

Biometrics 2012 Sep 19;68(3):774-83. Epub 2012 Jan 19.

Department of Biostatistics and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1111/j.1541-0420.2011.01730.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449228PMC
September 2012

FDM: a graph-based statistical method to detect differential transcription using RNA-seq data.

Bioinformatics 2011 Oct 8;27(19):2633-40. Epub 2011 Aug 8.

Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1093/bioinformatics/btr458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179659PMC
October 2011

A probabilistic framework for aligning paired-end RNA-seq data.

Bioinformatics 2010 Aug 23;26(16):1950-7. Epub 2010 Jun 23.

Department of Computer Science, University of Kentucky, Lexington, KY, USA.

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http://dx.doi.org/10.1093/bioinformatics/btq336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916723PMC
August 2010

Cancer gene discovery in hepatocellular carcinoma.

J Hepatol 2010 Jun 20;52(6):921-9. Epub 2010 Mar 20.

Helmholtz Centre for Infection Research, Braunschweig 38124, Germany.

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http://dx.doi.org/10.1016/j.jhep.2009.12.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905725PMC
June 2010

Mapping duplicated sequences.

Nat Biotechnol 2009 Nov;27(11):1001-2

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http://dx.doi.org/10.1038/nbt1109-1001DOI Listing
November 2009

Pathogenesis of hepatocellular carcinoma and molecular therapies.

Curr Opin Gastroenterol 2009 May;25(3):186-94

Mount Sinai Liver Cancer Program, Division of Liver Diseases, Mount Sinai School of Medicine, New York, New York 10029, USA.

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https://insights.ovid.com/crossref?an=00001574-200905000-000
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http://dx.doi.org/10.1097/MOG.0b013e32832962a1DOI Listing
May 2009

Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression.

J Clin Invest 2009 Mar 16;119(3):465-77. Epub 2009 Feb 16.

Department of Human and Molecular Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA.

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http://dx.doi.org/10.1172/JCI36460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648696PMC
March 2009

High-resolution mapping of copy-number alterations with massively parallel sequencing.

Nat Methods 2009 Jan 30;6(1):99-103. Epub 2008 Nov 30.

Broad Institute, Massachusetts Institute of Technology, 7 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1038/nmeth.1276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630795PMC
January 2009

High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss.

Genes Chromosomes Cancer 2008 Jul;47(7):591-603

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1002/gcc.20561DOI Listing
July 2008

Determining physical constraints in transcriptional initiation complexes using DNA sequence analysis.

PLoS One 2007 Nov 21;2(11):e1199. Epub 2007 Nov 21.

Department of Molecular and Cell Biology, University of California, Berkeley, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001199PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077805PMC
November 2007

Genomics and signaling pathways in hepatocellular carcinoma.

Semin Liver Dis 2007 Feb;27(1):55-76

Mount Sinai Liver Cancer Program, Division of Liver Diseases, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-2006-960171
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http://dx.doi.org/10.1055/s-2006-960171DOI Listing
February 2007

Flexible promoter architecture requirements for coactivator recruitment.

BMC Mol Biol 2006 Apr 28;7:16. Epub 2006 Apr 28.

Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.

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http://bmcmolbiol.biomedcentral.com/articles/10.1186/1471-21
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http://dx.doi.org/10.1186/1471-2199-7-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488866PMC
April 2006

Conservation and evolution of cis-regulatory systems in ascomycete fungi.

PLoS Biol 2004 Dec 9;2(12):e398. Epub 2004 Nov 9.

Genome Sciences Department, Genomics Division, Lawrence Berkeley National Laboratory , Berkeley, California, USA.

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https://dx.plos.org/10.1371/journal.pbio.0020398
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http://dx.doi.org/10.1371/journal.pbio.0020398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC526180PMC
December 2004

Position specific variation in the rate of evolution in transcription factor binding sites.

BMC Evol Biol 2003 Aug 28;3:19. Epub 2003 Aug 28.

Graduate Group in Biophysics, University of California, Berkeley, CA 94720, USA.

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http://bmcevolbiol.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2148-3-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC212491PMC
August 2003

Phylogenetically and spatially conserved word pairs associated with gene-expression changes in yeasts.

Genome Biol 2003 26;4(7):R43. Epub 2003 Jun 26.

Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1186/gb-2003-4-7-r43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC193630PMC
July 2003