Derek C Radisky

Derek C Radisky

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Derek C Radisky

Derek C Radisky

Publications by authors named "Derek C Radisky"

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Evaluation of 2 breast cancer risk models in a benign breast disease cohort.

Cancer 2018 08 22;124(16):3319-3328. Epub 2018 Jun 22.

Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/cncr.31528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108911PMC
August 2018

Model for Predicting Breast Cancer Risk in Women With Atypical Hyperplasia.

J Clin Oncol 2018 06 20;36(18):1840-1846. Epub 2018 Apr 20.

Amy C. Degnim, Stacey J. Winham, Ryan D. Frank, Robert A. Vierkant, Marlene H. Frost, Tanya L. Hoskin, Celine M. Vachon, Karthik Ghosh, Tina J. Hieken, Jodi M. Carter, Lori A. Denison, Brendan Broderick, Lynn C. Hartmann, and Daniel W. Visscher, Mayo Clinic, Rochester, MN; V. Shane Pankratz, University of New Mexico Health Sciences Center, Albuquerque, NM; William D. Dupont, Vanderbilt University, Nashville, TN; and Derek C. Radisky, Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1200/JCO.2017.75.9480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008107PMC
June 2018

Microfluidic chest cavities reveal that transmural pressure controls the rate of lung development.

Development 2017 12 30;144(23):4328-4335. Epub 2017 Oct 30.

Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ 08544, USA.

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http://dx.doi.org/10.1242/dev.154823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769635PMC
December 2017

Therapeutic Potential of Matrix Metalloproteinase Inhibition in Breast Cancer.

J Cell Biochem 2017 11 17;118(11):3531-3548. Epub 2017 Jul 17.

Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville 32224, Florida.

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http://dx.doi.org/10.1002/jcb.26185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621753PMC
November 2017

The exon 38-containing ARHGEF11 splice isoform is differentially expressed and is required for migration and growth in invasive breast cancer cells.

Oncotarget 2017 Nov 18;8(54):92157-92170. Epub 2017 Sep 18.

Department of Biochemistry, School of Medicine, Dokkyo Medical University, Mibu, Tochigi, Japan.

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http://dx.doi.org/10.18632/oncotarget.20985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696171PMC
November 2017

Tissue Stiffness and Hypoxia Modulate the Integrin-Linked Kinase ILK to Control Breast Cancer Stem-like Cells.

Cancer Res 2016 09 8;76(18):5277-87. Epub 2016 Aug 8.

Department of Chemical & Biological Engineering, Princeton University, Princeton, New Jersey. Department of Molecular Biology, Princeton University, Princeton, New Jersey.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026611PMC
September 2016

Foxa1 is essential for mammary duct formation.

Genesis 2016 05 29;54(5):277-85. Epub 2016 Mar 29.

Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida.

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http://dx.doi.org/10.1002/dvg.22929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419034PMC
May 2016

Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy.

Biochem J 2016 05 8;473(10):1329-41. Epub 2016 Mar 8.

Department of Biotechnology Engineering and the National Institute of Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel

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http://dx.doi.org/10.1042/BJ20151410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898653PMC
May 2016

Localized Smooth Muscle Differentiation Is Essential for Epithelial Bifurcation during Branching Morphogenesis of the Mammalian Lung.

Dev Cell 2015 Sep 18;34(6):719-26. Epub 2015 Sep 18.

Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2015.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589145PMC
September 2015

Mechanically patterning the embryonic airway epithelium.

Proc Natl Acad Sci U S A 2015 Jul 13;112(30):9230-5. Epub 2015 Jul 13.

Department of Chemical & Biological Engineering, Princeton University, Princeton, NJ 08544; Department of Molecular Biology, Princeton University, Princeton, NJ 08544

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http://www.pnas.org/content/112/30/9230.full.pdf
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http://www.pnas.org/lookup/doi/10.1073/pnas.1504102112
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http://dx.doi.org/10.1073/pnas.1504102112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522767PMC
July 2015

Matrix metalloproteinases as breast cancer drivers and therapeutic targets.

Front Biosci (Landmark Ed) 2015 Jun 1;20:1144-63. Epub 2015 Jun 1.

Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, Florida 32224,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516284PMC
June 2015

Model for individualized prediction of breast cancer risk after a benign breast biopsy.

J Clin Oncol 2015 Mar 26;33(8):923-9. Epub 2015 Jan 26.

V. Shane Pankratz, University of New Mexico Health Sciences Center, Albuquerque, NM; Amy C. Degnim, Ryan D. Frank, Marlene H. Frost, Daniel W. Visscher, Robert A. Vierkant, Tina J. Hieken, Karthik Ghosh, Celine M. Vachon, and Lynn C. Hartmann, Mayo Clinic, Rochester, MN; Yaman Tarabishy, Washington University, St Louis, St Louis, MO; and Derek C. Radisky, Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1200/JCO.2014.55.4865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348637PMC
March 2015

Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.

Cancer Inform 2015 9;14(Suppl 3):1-13. Epub 2015 Feb 9.

Department of Cancer Biology, Mayo Clinic Cancer Center, Jacksonville, FL USA.

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http://dx.doi.org/10.4137/CIN.S18965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325704PMC
February 2015

Lattice-based model of ductal carcinoma in situ suggests rules for breast cancer progression to an invasive state.

PLoS Comput Biol 2014 Dec 4;10(12):e1003997. Epub 2014 Dec 4.

Department of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey, United States of America; Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1003997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256017PMC
December 2014

CCAAT/enhancer binding protein beta (C/EBPβ) isoform balance as a regulator of epithelial-mesenchymal transition in mouse mammary epithelial cells.

Exp Cell Res 2014 Sep 29;327(1):146-55. Epub 2014 May 29.

Department of Bioscience, Graduate School of Science and Technology, Kwansei Gakuin University, Hyogo, 2-1 Gakuen, Sanda 669-1337 Japan. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.05.019DOI Listing
September 2014

Cutting the brakes and flooring the gas: how TMEPAI turns TGF-β into a tumor promoter.

Genes Cancer 2014 Sep;5(9-10):303-5

Mayo Clinic Cancer Center, Jacksonville, FL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209605PMC
http://dx.doi.org/10.18632/genesandcancer.34DOI Listing
September 2014

The importance of matrix metalloproteinase-3 in respiratory disorders.

Expert Rev Respir Med 2014 Aug 29;8(4):411-21. Epub 2014 May 29.

Department of Medicine, University of Western Ontario, London, ON, Canada.

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http://dx.doi.org/10.1586/17476348.2014.909288DOI Listing
August 2014

ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of Snail.

Oncotarget 2014 May;5(9):2827-38

Mayo Clinic Cancer Center, 4500 San Pablo Road, Jacksonville, FL 32224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058048PMC
http://dx.doi.org/10.18632/oncotarget.1940DOI Listing
May 2014

Sclerosing adenosis and risk of breast cancer.

Breast Cancer Res Treat 2014 Feb 8;144(1):205-12. Epub 2014 Feb 8.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1007/s10549-014-2862-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924024PMC
February 2014

Extracellular matrix proteins regulate epithelial-mesenchymal transition in mammary epithelial cells.

Differentiation 2013 Oct 6;86(3):126-32. Epub 2013 May 6.

Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA.

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http://dx.doi.org/10.1016/j.diff.2013.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762919PMC
October 2013

Epimorphin is a novel regulator of the progesterone receptor isoform-a.

Cancer Res 2013 Sep 18;73(18):5719-29. Epub 2013 Jul 18.

Authors' Affiliations: Life Science Division, Lawrence Berkeley National Laboratory, Berkeley, California; Mayo Clinic Cancer Center, Jacksonville, Florida; College of Staten Island, City University of New York, Staten Island, New York; and Department of Bioscience, Kwansei Gakuin University, Sanda, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783262PMC
September 2013

Triggering the landslide: The tumor-promotional effects of myofibroblasts.

Exp Cell Res 2013 Jul 22;319(11):1657-62. Epub 2013 Mar 22.

Mayo Clinic Cancer Center, Jacksonville, FL 32225, United States. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2013.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748147PMC
July 2013

PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer.

Mol Cancer Res 2012 Dec;10(12):1555-66

Department of Cancer Biology, Mayo Clinic, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-12-0314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531873PMC
December 2012

Host epithelial geometry regulates breast cancer cell invasiveness.

Proc Natl Acad Sci U S A 2012 Nov 12;109(48):19632-7. Epub 2012 Nov 12.

Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA.

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http://dx.doi.org/10.1073/pnas.1118872109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511712PMC
November 2012

Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition.

Mol Biol Cell 2012 Oct 23;23(20):4097-108. Epub 2012 Aug 23.

Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA.

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http://www.molbiolcell.org/doi/10.1091/mbc.e12-02-0166
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http://dx.doi.org/10.1091/mbc.E12-02-0166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469523PMC
October 2012

Involvement of hnRNP A1 in the matrix metalloprotease-3-dependent regulation of Rac1 pre-mRNA splicing.

J Cell Biochem 2012 Jul;113(7):2319-29

Instituto de Fisiología, Biología Molecular y Neurociencias-Consejo Nacional de Investigaciones Científicas y Técnicas, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1002/jcb.24103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927408PMC
July 2012

Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure.

J Biol Chem 2012 May 16;287(19):15935-46. Epub 2012 Mar 16.

Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, Florida 32224, USA.

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http://dx.doi.org/10.1074/jbc.M112.341156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346077PMC
May 2012

Growth of lung cancer cells in three-dimensional microenvironments reveals key features of tumor malignancy.

Integr Biol (Camb) 2012 Apr 17;4(4):440-8. Epub 2011 Nov 17.

Department of Cancer Biology, Mayo Clinic, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1039/c1ib00090jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772507PMC
April 2012

Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases.

Cold Spring Harb Perspect Biol 2012 Feb 1;4(2). Epub 2012 Feb 1.

Laboratory of Immunology, Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1101/cshperspect.a011908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281569PMC
February 2012

Tissue composition of mammographically dense and non-dense breast tissue.

Breast Cancer Res Treat 2012 Jan 30;131(1):267-75. Epub 2011 Aug 30.

Department of Medicine, Mayo Clinic College of Medicine, Charlton 6-239, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1007/s10549-011-1727-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707294PMC
January 2012

p16(INK4a) expression and breast cancer risk in women with atypical hyperplasia.

Cancer Prev Res (Phila) 2011 Dec 15;4(12):1953-60. Epub 2011 Sep 15.

Division of Biochemistry/Molecular Biology, Mayo Clinic in Jacksonville, Jacksonville, Florida 32224, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232312PMC
December 2011

TGFbeta/TNF(alpha)-mediated epithelial-mesenchymal transition generates breast cancer stem cells with a claudin-low phenotype.

Cancer Res 2011 Jul 9;71(13):4707-19. Epub 2011 May 9.

Department of Immunology and Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-4554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129359PMC
July 2011

Identifying the stroma as a critical player in radiation-induced mammary tumor development.

Cancer Cell 2011 May;19(5):571-2

Department of Cancer Biology, Mayo Clinic Cancer Center, Jacksonville, FL 32225, USA.

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http://dx.doi.org/10.1016/j.ccr.2011.05.001DOI Listing
May 2011

Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis.

EMBO J 2011 May 24;30(13):2662-74. Epub 2011 May 24.

Departments of Chemical & Biological Engineering and Molecular Biology, Princeton University, Princeton, NJ, USA.

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http://dx.doi.org/10.1038/emboj.2011.159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155296PMC
May 2011

Microenvironmental influences that drive progression from benign breast disease to invasive breast cancer.

J Mammary Gland Biol Neoplasia 2010 Dec 16;15(4):389-97. Epub 2010 Dec 16.

Department of Cancer Biology, Mayo Clinic, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1007/s10911-010-9195-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011086PMC
December 2010

Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109.

Breast Cancer Res Treat 2010 Nov 25;124(1):27-38. Epub 2009 Dec 25.

Mayo Clinic Cancer Center, 4500 San Pablo Road, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1007/s10549-009-0699-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929293PMC
November 2010

Separation anxiety: detachment from the extracellular matrix induces metabolic changes that can stimulate tumorigenesis.

J Mol Cell Biol 2010 Jun 18;2(3):113-5. Epub 2009 Dec 18.

Mayo Clinic Cancer Center, Jacksonville, FL 32225, USA.

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http://dx.doi.org/10.1093/jmcb/mjp050DOI Listing
June 2010

Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer.

J Mammary Gland Biol Neoplasia 2010 Jun 5;15(2):201-12. Epub 2010 May 5.

Mayo Clinic Cancer Center, Griffin Building, 4500 San Pablo Road, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1007/s10911-010-9177-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886087PMC
June 2010

Association between mammographic density and age-related lobular involution of the breast.

J Clin Oncol 2010 May 29;28(13):2207-12. Epub 2010 Mar 29.

Division of General Internal Medicine, Department of Internal Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1200/JCO.2009.23.4120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860438PMC
May 2010

Novel breast tissue feature strongly associated with risk of breast cancer.

J Clin Oncol 2009 Dec 5;27(35):5893-8. Epub 2009 Oct 5.

Department of Oncology, Mayo Clinic Cancer Center, Mayo Graduate School of Medical Education, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1200/JCO.2008.21.5079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793038PMC
December 2009