Publications by authors named "Derek C Angus"

98Publications

Association Between State Medicaid Expansion and Emergency Access to Acute Care Hospitals in the United States.

JAMA Netw Open 2020 Nov 2;3(11):e2025815. Epub 2020 Nov 2.

Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jamanetworkopen.2020.25815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670316PMC
November 2020

Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial.

Authors:
Wesley H Self Matthew W Semler Lindsay M Leither Jonathan D Casey Derek C Angus Roy G Brower Steven Y Chang Sean P Collins John C Eppensteiner Michael R Filbin D Clark Files Kevin W Gibbs Adit A Ginde Michelle N Gong Frank E Harrell Douglas L Hayden Catherine L Hough Nicholas J Johnson Akram Khan Christopher J Lindsell Michael A Matthay Marc Moss Pauline K Park Todd W Rice Bryce R H Robinson David A Schoenfeld Nathan I Shapiro Jay S Steingrub Christine A Ulysse Alexandra Weissman Donald M Yealy B Taylor Thompson Samuel M Brown Jay Steingrub Howard Smithline Bogdan Tiru Mark Tidswell Lori Kozikowski Sherell Thornton-Thompson Leslie De Souza Peter Hou Rebecca Baron Anthony Massaro Imoigele Aisiku Lauren Fredenburgh Raghu Seethala Lily Johnsky Richard Riker David Seder Teresa May Michael Baumann Ashley Eldridge Nathan Shapiro Daniel Talmor Thomas O’Mara Charlotte Kirk Kelly Harrison Lisa Kurt Margaret Schermerhorn Valerie Banner-Goodspeed Katherine Boyle Nicole Dubosh Michael Filbin Kathryn Hibbert Blair Parry Kendall Lavin-Parsons Natalie Pulido Brendan Lilley Carl Lodenstein Justin Margolin Kelsey Brait Alan Jones James Galbraith Rebekah Peacock Utsav Nandi Taylor Wachs Michael Matthay Kathleen Liu Kirsten Kangelaris Ralph Wang Carolyn Calfee Kimberly Yee Gregory Hendey Steven Chang George Lim Nida Qadir Andrea Tam Rebecca Beutler Joseph Levitt Jenny Wilson Angela Rogers Rosemary Vojnik Jonasel Roque Timothy Albertson James Chenoweth Jason Adams Skyler Pearson Maya Juarez Eyad Almasri Mohamed Fayed Alyssa Hughes Shelly Hillard Ryan Huebinger Henry Wang Elizabeth Vidales Bela Patel Adit Ginde Marc Moss Amiran Baduashvili Jeffrey McKeehan Lani Finck Carrie Higgins Michelle Howell Ivor Douglas Jason Haukoos Terra Hiller Carolynn Lyle Alicia Cupelo Emily Caruso Claudia Camacho Stephanie Gravitz James Finigan Christine Griesmer Pauline Park Robert Hyzy Kristine Nelson Kelli McDonough Norman Olbrich Mark Williams Raj Kapoor Jean Nash Meghan Willig Henry Ford Jayna Gardner-Gray Mayur Ramesh Montefiore Moses Michelle Ng Gong Michael Aboodi Ayesha Asghar Omowunmi Amosu Madeline Torres Savneet Kaur Montefiore Weiler Jen-Ting Chen Aluko Hope Brenda Lopez Kathleen Rosales Jee Young You Jarrod Mosier Cameron Hypes Bhupinder Natt Bryan Borg Elizabeth Salvagio R. Duncan Hite Kristin Hudock Autumn Cresie Faysal Alhasan Jose Gomez-Arroyo Abhijit Duggal Omar Mehkri Andrei Hastings Debasis Sahoo Francois Abi Fadel Susan Gole Valerie Shaner Allison Wimer Yvonne Meli Alexander King Thomas Terndrup Matthew Exline Sonal Pannu Emily Robart Sarah Karow Catherine Hough Bryce Robinson Nicholas Johnson Daniel Henning Monica Campo Stephanie Gundel Sakshi Seghal Sarah Katsandres Sarah Dean Akram Khan Olivia Krol Milad Jouzestani Peter Huynh Alexandra Weissman Donald Yealy Denise Scholl Peter Adams Bryan McVerry David Huang Derek Angus Jordan Schooler Steven Moore D. Clark Files Chadwick Miller Kevin Gibbs Mary LaRose Lori Flores Lauren Koehler Caryn Morse John Sanders Caitlyn Langford Kristen Nanney Masiku MdalaGausi Phyllis Yeboah Peter Morris Jamie Sturgill Sherif Seif Evan Cassity Sanjay Dhar Marjolein de Wit Jessica Mason Andrew Goodwin Greg Hall Abbey Grady Amy Chamberlain Samuel Brown Joseph Bledsoe Lindsay Leither Ithan Peltan Nathan Starr Melissa Fergus Valerie Aston Quinn Montgomery Rilee Smith Mardee Merrill Katie Brown Brent Armbruster Estelle Harris Elizabeth Middleton Robert Paine Stacy Johnson Macy Barrios John Eppensteiner Alexander Limkakeng Lauren McGowan Tedra Porter Andrew Bouffler J. Clancy Leahy Bennet deBoisblanc Matthew Lammi Kyle Happel Paula Lauto Wesley Self Jonathan Case Matthew Semler Sean Collins Frank Harrell Christopher Lindsell Todd Rice William Stubblefield Christopher Gray Jakea Johnson Megan Roth Margaret Hays Donna Torr Arwa Zakaria David Schoenfeld B. Taylor Thompson Douglas Hayden Nancy Ringwood Cathryn Oldmixon Christine Ulysse Richard Morse Ariela Muzikansky Laura Fitzgerald Samuel Whitaker Adrian Lagakos Lora Reineck Neil Aggarwal Karen Bienstock Michelle Freemer Myron Maclawiw Gail Weinmann Laurie Morrison Mark Gillespie Richard Kryscio Daniel Brodie Wojciech Zareba Anne Rompalo Michael Boeckh Polly Parsons Jason Christie Jesse Hall Nicholas Horton Laurie Zoloth Neal Dickert Deborah Diercks

JAMA 2020 11 9. Epub 2020 Nov 9.

Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, Utah.

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http://dx.doi.org/10.1001/jama.2020.22240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653542PMC
November 2020

Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis.

PLoS One 2020 5;15(11):e0241122. Epub 2020 Nov 5.

Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0241122PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643993PMC
November 2020

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.

Authors:
Derek C Angus Lennie Derde Farah Al-Beidh Djillali Annane Yaseen Arabi Abigail Beane Wilma van Bentum-Puijk Lindsay Berry Zahra Bhimani Marc Bonten Charlotte Bradbury Frank Brunkhorst Meredith Buxton Adrian Buzgau Allen C Cheng Menno de Jong Michelle Detry Lise Estcourt Mark Fitzgerald Herman Goossens Cameron Green Rashan Haniffa Alisa M Higgins Christopher Horvat Sebastiaan J Hullegie Peter Kruger Francois Lamontagne Patrick R Lawler Kelsey Linstrum Edward Litton Elizabeth Lorenzi John Marshall Daniel McAuley Anna McGlothin Shay McGuinness Bryan McVerry Stephanie Montgomery Paul Mouncey Srinivas Murthy Alistair Nichol Rachael Parke Jane Parker Kathryn Rowan Ashish Sanil Marlene Santos Christina Saunders Christopher Seymour Anne Turner Frank van de Veerdonk Balasubramanian Venkatesh Ryan Zarychanski Scott Berry Roger J Lewis Colin McArthur Steven A Webb Anthony C Gordon Farah Al-Beidh Derek Angus Djillali Annane Yaseen Arabi Wilma van Bentum-Puijk Scott Berry Abigail Beane Zahra Bhimani Marc Bonten Charlotte Bradbury Frank Brunkhorst Meredith Buxton Allen Cheng Menno De Jong Lennie Derde Lise Estcourt Herman Goossens Anthony Gordon Cameron Green Rashan Haniffa Francois Lamontagne Patrick Lawler Edward Litton John Marshall Colin McArthur Daniel McAuley Shay McGuinness Bryan McVerry Stephanie Montgomery Paul Mouncey Srinivas Murthy Alistair Nichol Rachael Parke Kathryn Rowan Christopher Seymour Anne Turner Frank van de Veerdonk Steve Webb Ryan Zarychanski Lewis Campbell Andrew Forbes David Gattas Stephane Heritier Lisa Higgins Peter Kruger Sandra Peake Jeffrey Presneill Ian Seppelt Tony Trapani Paul Young Sean Bagshaw Nick Daneman Niall Ferguson Cheryl Misak Marlene Santos Sebastiaan Hullegie Mathias Pletz Gernot Rohde Kathy Rowan Brian Alexander Kim Basile Timothy Girard Christopher Horvat David Huang Kelsey Linstrum Jennifer Vates Richard Beasley Robert Fowler Steve McGloughlin Susan Morpeth David Paterson Bala Venkatesh Tim Uyeki Kenneth Baillie Eamon Duffy Rob Fowler Thomas Hills Katrina Orr Asad Patanwala Steve Tong Mihai Netea Shilesh Bihari Marc Carrier Dean Fergusson Ewan Goligher Ghady Haidar Beverley Hunt Anand Kumar Mike Laffan Patrick Lawless Sylvain Lother Peter McCallum Saskia Middeldopr Zoe McQuilten Matthew Neal John Pasi Roger Schutgens Simon Stanworth Alexis Turgeon Alexandra Weissman Neill Adhikari Matthew Anstey Emily Brant Angelique de Man Francois Lamonagne Marie-Helene Masse Andrew Udy Donald Arnold Phillipe Begin Richard Charlewood Michael Chasse Mark Coyne Jamie Cooper James Daly Iain Gosbell Heli Harvala-Simmonds Tom Hills Sheila MacLennan David Menon John McDyer Nicole Pridee David Roberts Manu Shankar-Hari Helen Thomas Alan Tinmouth Darrell Triulzi Tim Walsh Erica Wood Carolyn Calfee Cecilia O’Kane Murali Shyamsundar Pratik Sinha Taylor Thompson Ian Young Shailesh Bihari Carol Hodgson John Laffey Danny McAuley Neil Orford Ary Neto Michelle Detry Mark Fitzgerald Roger Lewis Anna McGlothlin Ashish Sanil Christina Saunders Lindsay Berry Elizabeth Lorenzi Eliza Miller Vanessa Singh Claire Zammit Wilma van Bentum Puijk Wietske Bouwman Yara Mangindaan Lorraine Parker Svenja Peters Ilse Rietveld Kik Raymakers Radhika Ganpat Nicole Brillinger Rene Markgraf Kate Ainscough Kathy Brickell Aisha Anjum Janis-Best Lane Alvin Richards-Belle Michelle Saull Daisy Wiley Julian Bion Jason Connor Simon Gates Victoria Manax Tom van der Poll John Reynolds Marloes van Beurden Evelien Effelaar Joost Schotsman Craig Boyd Cain Harland Audrey Shearer Jess Wren Giles Clermont William Garrard Kyle Kalchthaler Andrew King Daniel Ricketts Salim Malakoutis Oscar Marroquin Edvin Music Kevin Quinn Heidi Cate Karen Pearson Joanne Collins Jane Hanson Penny Williams Shane Jackson Adeeba Asghar Sarah Dyas Mihaela Sutu Sheenagh Murphy Dawn Williamson Nhlanhla Mguni Alison Potter David Porter Jayne Goodwin Clare Rook Susie Harrison Hannah Williams Hilary Campbell Kaatje Lomme James Williamson Jonathan Sheffield Willian van’t Hoff Phobe McCracken Meredith Young Jasmin Board Emma Mart Cameron Knott Julie Smith Catherine Boschert Julia Affleck Mahesh Ramanan Ramsy D’Souza Kelsey Pateman Arif Shakih Winston Cheung Mark Kol Helen Wong Asim Shah Atul Wagh Joanne Simpson Graeme Duke Peter Chan Brittney Cartner Stephanie Hunter Russell Laver Tapaswi Shrestha Adrian Regli Annamaria Pellicano James McCullough Mandy Tallott Nikhil Kumar Rakshit Panwar Gail Brinkerhoff Cassandra Koppen Federica Cazzola Matthew Brain Sarah Mineall Roy Fischer Vishwanath Biradar Natalie Soar Hayden White Kristen Estensen Lynette Morrison Joanne Smith Melanie Cooper Monash Health Yahya Shehabi Wisam Al-Bassam Amanda Hulley Christina Whitehead Julie Lowrey Rebecca Gresha James Walsham Jason Meyer Meg Harward Ellen Venz Patricia Williams Catherine Kurenda Kirsy Smith Margaret Smith Rebecca Garcia Deborah Barge Deborah Byrne Kathleen Byrne Alana Driscoll Louise Fortune Pierre Janin Elizabeth Yarad Naomi Hammond Frances Bass Angela Ashelford 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Siobhan Casey Maeve Kernan Peter Doran Michael O’Dywer Michelle Smyth Leanne Hayes Oscar Hoiting Marco Peters Els Rengers Mirjam Evers Anton Prinssen Jeroen Bosch Ziekenhuis Koen Simons Wim Rozendaal F Polderman P de Jager M Moviat A Paling A Salet Emma Rademaker Anna Linda Peters E de Jonge J Wigbers E Guilder M Butler Keri-Anne Cowdrey Lynette Newby Yan Chen Catherine Simmonds Rachael McConnochie Jay Ritzema Carter Seton Henderson Kym Van Der Heyden Jan Mehrtens Tony Williams Alex Kazemi Rima Song Vivian Lai Dinu Girijadevi Robert Everitt Robert Russell Danielle Hacking Ulrike Buehner Erin Williams Troy Browne Kate Grimwade Jennifer Goodson Owen Keet Owen Callender Robert Martynoga Kara Trask Amelia Butler Livia Schischka Chelsea Young Eden Lesona Shaanti Olatunji Yvonne Robertson Nuno José Teodoro Amaro dos Santos Catorze Tiago Nuno Alfaro de Lima Pereira Lucilia Maria Neves Pessoa Ricardo Manuel Castro Ferreira Joana Margarida Pereira Sousa Bastos Simin Aysel Florescu Delia Stanciu 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Artaraz Leilani Cabreros Ian White Maria Croft Nicky Holland Rita Pereira Ahmed Zaki David Johnson Matthew Jackson Hywel Garrard Vera Juhaz Alistair Roy Anthony Rostron Lindsey Woods Sarah Cornell Suresh Pillai Rachel Harford Tabitha Rees Helen Ivatt Ajay Sundara Raman Miriam Davey Kelvin Lee Russell Barber Manish Chablani Farooq Brohi Vijay Jagannathan Michele Clark Sarah Purvis Bill Wetherill Ahilanandan Dushianthan Rebecca Cusack Kim de Courcy-Golder Simon Smith Susan Jackson Ben Attwood Penny Parsons Valerie Page Xiao Bei Zhao Deepali Oza Jonathan Rhodes Tom Anderson Sheila Morris Charlotte Xia Le Tai Amy Thomas Alexandra Keen Stephen Digby Nicholas Cowley Laura Wild David Southern Harsha Reddy Andy Campbell Claire Watkins Sara Smuts Omar Touma Nicky Barnes Peter Alexander Tim Felton Susan Ferguson Katharine Sellers Joanne Bradley-Potts David Yates Isobel Birkinshaw Kay Kell Nicola Marshall Lisa Carr-Knott

JAMA 2020 10;324(13):1317-1329

Division of Anaesthetics, Pain Medicine and Intensive Care Medicine, Department of Surgery and Cancer, Imperial College London and Imperial College Healthcare NHS Trust, London, United Kingdom.

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http://dx.doi.org/10.1001/jama.2020.17022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489418PMC
October 2020

Efficacy of Remdesivir in COVID-19.

JAMA 2020 09;324(11):1041-1042

Department of Critical Care Medicine, UPMC Health System and The University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2020.16337DOI Listing
September 2020

Plasma lipid profiling for the prognosis of 90-day mortality, in-hospital mortality, ICU admission, and severity in bacterial community-acquired pneumonia (CAP).

Crit Care 2020 07 27;24(1):461. Epub 2020 Jul 27.

Department of Critical Care Medicine, Faculty of Medicine, Health Research Innovation Center (HRIC), University of Calgary, Room 4C64, 3280 Hospital Drive N.W, Calgary, Alberta, T2N 4Z6, Canada.

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http://dx.doi.org/10.1186/s13054-020-03147-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385943PMC
July 2020

Brain MR imaging and spectroscopy for outcome prognostication after pediatric cardiac arrest.

Resuscitation 2020 Jul 9. Epub 2020 Jul 9.

Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA; Department of Radiology, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.resuscitation.2020.06.033DOI Listing
July 2020

Pediatric Outcomes After Regulatory Mandates for Sepsis Care.

Pediatrics 2020 07;146(1)

Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine,

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http://dx.doi.org/10.1542/peds.2019-3353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329251PMC
July 2020

Oxygen Therapy in the ICU. Reply.

Authors:
Derek C Angus

N Engl J Med 2020 06;382(26):2579

University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1056/NEJMc2009489DOI Listing
June 2020

A Proposed Lottery System to Allocate Scarce COVID-19 Medications: Promoting Fairness and Generating Knowledge.

JAMA 2020 07;324(4):329-330

University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2020.11464DOI Listing
July 2020

Sepsis-Associated Acute Kidney Disease.

Kidney Int Rep 2020 Jun 12;5(6):839-850. Epub 2020 Mar 12.

Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.ekir.2020.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270721PMC
June 2020

Optimizing the Trade-off Between Learning and Doing in a Pandemic.

Authors:
Derek C Angus

JAMA 2020 May;323(19):1895-1896

University of Pittsburgh and UPMC Health System, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2020.4984DOI Listing
May 2020

Toward Universal Deployable Guidelines for the Care of Patients With COVID-19.

JAMA 2020 05;323(18):1786-1787

Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2020.5110DOI Listing
May 2020

Oxygen Therapy for the Critically Ill.

Authors:
Derek C Angus

N Engl J Med 2020 03;382(11):1054-1056

From the University of Pittsburgh School of Medicine, Pittsburgh.

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http://dx.doi.org/10.1056/NEJMe2000800DOI Listing
March 2020

Prehospital identification of community sepsis using biomarkers of host response.

Intensive Care Med 2020 04 24;46(4):823-824. Epub 2020 Feb 24.

Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1007/s00134-020-05975-xDOI Listing
April 2020

Selepressin for Patients With Septic Shock-Reply.

JAMA 2020 02;323(7):667-668

Department of Emergency Medicine, Harbor-UCLA Medical Center, Torrance, California.

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http://dx.doi.org/10.1001/jama.2019.20863DOI Listing
February 2020

Randomized Clinical Trials of Artificial Intelligence.

Authors:
Derek C Angus

JAMA 2020 03;323(11):1043-1045

University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2020.1039DOI Listing
March 2020

Effective Care Practices in Patients Receiving Prolonged Mechanical Ventilation. An Ethnographic Study.

Am J Respir Crit Care Med 2020 04;201(7):823-831

Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1164/rccm.201910-2006OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124716PMC
April 2020

Longer-Term Outcomes of the ProACT Trial.

N Engl J Med 2020 01;382(5):485-486

University of Pittsburgh, Pittsburgh, PA

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http://dx.doi.org/10.1056/NEJMc1910508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332226PMC
January 2020

Murine sepsis phenotypes and differential treatment effects in a randomized trial of prompt antibiotics and fluids.

Crit Care 2019 11 28;23(1):384. Epub 2019 Nov 28.

Departments of Critical Care Medicine Emergency Medicine, University of Pittsburgh School of Medicine, 3550 Terrace St, Scaife Hall, #639, Pittsburgh, PA, 15261, USA.

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http://dx.doi.org/10.1186/s13054-019-2655-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883631PMC
November 2019

Identifying Sepsis Phenotypes-Reply.

JAMA 2019 10;322(14):1417

Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2019.12595DOI Listing
October 2019

Is High-Dose Vitamin C Beneficial for Patients With Sepsis?

JAMA 2019 10;322(13):1257-1258

Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2019.11643DOI Listing
October 2019

Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome. Reply.

N Engl J Med 2019 08;381(8):787-788

University of Pittsburgh School of Medicine, Pittsburgh, PA

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http://dx.doi.org/10.1056/NEJMc1908874DOI Listing
August 2019

The authors reply.

Crit Care Med 2019 09;47(9):e788-e789

Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA Department of Surgery, University of Florida College of Medicine, Gainesville, FL Department of Medicine, The Ohio State University School of Medicine, Columbus, OH Department of Medicine, Emory University School of Medicine, Atlanta, GA Department of Surgery, Emory University School of Medicine, Atlanta, GA University of Florida College of Medicine, Gainesville, FL Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI.

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September 2019

Discharge Destination As a Marker of Mobility Impairment in Survivors of Acute Respiratory Distress Syndrome.

Crit Care Med 2019 10;47(10):e814-e819

Division of Pulmonary and Critical Care Medicine, University of Washington School of Medicine, Seattle, WA.

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http://dx.doi.org/10.1097/CCM.0000000000003906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133788PMC
October 2019

Association Between State-Mandated Protocolized Sepsis Care and In-hospital Mortality Among Adults With Sepsis.

JAMA 2019 07;322(3):240-250

CRISMA Center, Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2019.9021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635905PMC
July 2019

Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome.

N Engl J Med 2019 05 19;380(21):1997-2008. Epub 2019 May 19.

The affiliations of the members of the writing committee are as follows: the Departments of Medicine (M.M.) and Emergency Medicine (A.A.G.), University of Colorado School of Medicine, Aurora; the Departments of Critical Care Medicine (D.T.H., D.C.A.) and Emergency Medicine (D.M.Y.), University of Pittsburgh School of Medicine, Pittsburgh; the Department of Medicine, Johns Hopkins University School of Medicine, Baltimore (R.G.B.); the Interdepartmental Division of Critical Care Medicine, Department of Medicine, University Health Network and Sinai Health System, University of Toronto, Toronto (N.D.F.); the Department of Medicine, Montefiore Hospital, New York (M.N.G.); the Department of Medicine, Intermountain Medical Center and the University of Utah, Salt Lake City (C.K.G.); the Department of Medicine, University of Washington, Seattle (S.G., C.L.H.); the Biostatistics Center (D.H.), the Department of Medicine (B.T.T.), and the PETAL Network Clinical Coordinating Center (C.A.U.), Massachusetts General Hospital, the Department of Emergency Medicine, Division of Emergency Critical Care Medicine, Brigham and Women's Hospital (P.C.H.), and the Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center (D.T.) - all in Boston; the Department of Critical Care, Respiratory Institute, Cleveland Clinic, Cleveland (R.D.H.); the Department of Medicine, University of Michigan and Veterans Affairs Center for Clinical Research, Ann Arbor (T.J.I.); the Department of Medicine, Oregon Health and Science University, Portland (A.K.); and the Departments of Medicine and Anesthesia, University of California, San Francisco, San Francisco (K.D.L.).

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http://dx.doi.org/10.1056/NEJMoa1901686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741345PMC
May 2019

Does Preexisting Practice Modify How Video Games Recalibrate Physician Heuristics in Trauma Triage?

J Surg Res 2019 10 6;242:55-61. Epub 2019 May 6.

Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2019.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913034PMC
October 2019

Epidemiology of Readmissions After Sepsis Hospitalization in Children.

Hosp Pediatr 2019 04 1;9(4):249-255. Epub 2019 Mar 1.

Clinical Research, Investigation, and Systems Modeling of Acute Illness Center,

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http://dx.doi.org/10.1542/hpeds.2018-0175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434975PMC
April 2019

How Best to Resuscitate Patients With Septic Shock?

Authors:
Derek C Angus

JAMA 2019 02;321(7):647-648

University of Pittsburgh, Pittsburgh, Pennsylvania.

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February 2019

Sepsis Bundles and Mortality Among Pediatric Patients-Reply.

JAMA 2018 12;320(21):2271-2272

Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2018.16751DOI Listing
December 2018

Microcirculatory perfusion disturbances in septic shock: results from the ProCESS trial.

Crit Care 2018 Nov 20;22(1):308. Epub 2018 Nov 20.

Department of Emergency Medicine and Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, 1 Deaconess Road, CC2-W, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1186/s13054-018-2240-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245723PMC
November 2018

Validity of the qSOFA Score in Low- and Middle-Income Countries-Reply.

JAMA 2018 11;320(19):2039-2040

Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2018.14477DOI Listing
November 2018

Procalcitonin-Guided Antibiotic Use.

N Engl J Med 2018 11;379(20):1973

University of Pittsburgh, Pittsburgh, PA

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http://dx.doi.org/10.1056/NEJMc1811150DOI Listing
November 2018

Determinants of Intensive Care Unit Telemedicine Effectiveness. An Ethnographic Study.

Am J Respir Crit Care Med 2019 04;199(8):970-979

1 Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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https://www.atsjournals.org/doi/10.1164/rccm.201802-0259OC
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http://dx.doi.org/10.1164/rccm.201802-0259OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467312PMC
April 2019

Time for Clinicians to Embrace Their Inner Bayesian?: Reanalysis of Results of a Clinical Trial of Extracorporeal Membrane Oxygenation.

JAMA 2018 12;320(21):2208-2210

Department of Critical Care Medicine, Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2018.16916DOI Listing
December 2018

In vivo quantification of rolling and adhered leukocytes in human sepsis.

Crit Care 2018 09 30;22(1):240. Epub 2018 Sep 30.

Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 1 Deaconess Road, CC2-W, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1186/s13054-018-2173-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164176PMC
September 2018

The global burden of sepsis: barriers and potential solutions.

Crit Care 2018 09 23;22(1):232. Epub 2018 Sep 23.

International Respiratory and Severe Illness Center, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1186/s13054-018-2157-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151187PMC
September 2018

Serious games may improve physician heuristics in trauma triage.

Proc Natl Acad Sci U S A 2018 09 27;115(37):9204-9209. Epub 2018 Aug 27.

The Dartmouth Institute, Geisel School of Medicine at Dartmouth, Lebanon, NH 03766.

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http://dx.doi.org/10.1073/pnas.1805450115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140476PMC
September 2018

Evaluation of Repeated Quick Sepsis-Related Organ Failure Assessment Measurements Among Patients With Suspected Infection.

Crit Care Med 2018 12;46(12):1906-1913

Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1097/CCM.0000000000003360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309444PMC
December 2018

Arguing for Adaptive Clinical Trials in Sepsis.

Front Immunol 2018 28;9:1502. Epub 2018 Jun 28.

Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, United States.

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http://dx.doi.org/10.3389/fimmu.2018.01502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031704PMC
June 2018

Adults with septic shock and extreme hyperferritinemia exhibit pathogenic immune variation.

Genes Immun 2019 07 6;20(6):520-526. Epub 2018 Jul 6.

Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1038/s41435-018-0030-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320733PMC
July 2019

Long-term survival in patients with septic acute kidney injury is strongly influenced by renal recovery.

PLoS One 2018 5;13(6):e0198269. Epub 2018 Jun 5.

The Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988328PMC
December 2018

A Randomized Trial of a Family-Support Intervention in Intensive Care Units.

N Engl J Med 2018 Jun 23;378(25):2365-2375. Epub 2018 May 23.

From the Program on Ethics and Decision Making in Critical Illness (D.B.W., A.-M.S., P.B.), Clinical Research, Investigation, and Systems Modeling of Acute Illness Center (D.B.W., D.C.A., A.-M.S., P.B., C. Pidro, C.-C.H.C., J.M.K.), Department of Critical Care Medicine (D.B.W., D.C.A., A.-M.S., P.B., C. Pidro, C.-C.H.C., J.M.K., J.M.D.), and the Section of Palliative Care and Medical Ethics, Division of General Internal Medicine (R.M.A.), Department of Medicine (C.-C.H.C., R.M.A.), University of Pittsburgh School of Medicine, and the Intensive Care Unit Service Center (D.B.W., D.C.A., J.M.K.), the Wolff Center (C. Paner, A.K., S.M.), and the Palliative and Supportive Institute (E.C., R.M.A.), UPMC Health System - all in Pittsburgh; Eli Lilly, Indianapolis (F.P.); and the Statistics Collaborative, Washington, DC (L.W.).

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http://dx.doi.org/10.1056/NEJMoa1802637DOI Listing
June 2018

Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection.

N Engl J Med 2018 Jul 20;379(3):236-249. Epub 2018 May 20.

From the CRISMA (Clinical Research, Investigation, and Systems Modeling of Acute Illness) Center (D.T.H., C.-C.H.C., J.A.K., O.M.P.-P., D.C.A.), the Departments of Critical Care Medicine (D.T.H., J.A.K., O.M.P.-P., D.C.A.), Emergency Medicine (D.T.H., D.M.Y., A.M.B., H.P.), and Pathology (O.M.P.-P.), the MACRO (Multidisciplinary Acute Care Research Organization) Center (D.T.H., D.M.Y., D.C.A.), and the Divisions of General Internal Medicine (C.-C.H.C., M.J.F., J.Y.) and Infectious Diseases (Y.D.), University of Pittsburgh, and the Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System (M.J.F.) - all in Pittsburgh; the Department of Emergency Medicine, Massachusetts General Hospital (M.R.F.), the Department of Emergency Medicine, Beth Israel Deaconess Medical Center (M.W.D.), and the Department of Emergency Medicine, Brigham and Women's Hospital (P.C.H.) - all in Boston; the Department of Emergency Medicine, Norwalk Hospital, Norwalk, CT (J.F.); the Department of Emergency Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA (M.A.F., T.T.); the Department of Emergency Medicine, Essentia Health, Duluth, MN (J.M.H.); the Department of Emergency Medicine, University of Maryland Medical Center, Baltimore (F.K.); the Department of Emergency Medicine, University of Alabama at Birmingham Hospital, Birmingham (M.C.K.); the Department of Emergency Medicine, University of California at Irvine Medical Center, Irvine (S.L.); the Department of Emergency Medicine, Maricopa Medical Center, Phoenix, AZ (F.L.); Eli Lilly, Indianapolis (F.P.); the Department of Emergency Medicine, Detroit Receiving Hospital, Detroit (R.L.S.); the Department of Emergency Medicine, Ohio State University, Columbus (L.S., T.T.); and Statistics Collaborative, Washington, DC (L.A.W.).

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http://dx.doi.org/10.1056/NEJMoa1802670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197800PMC
July 2018

Children with Chronic Disease Bear the Highest Burden of Pediatric Sepsis.

J Pediatr 2018 08 9;199:194-199.e1. Epub 2018 May 9.

The Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA; Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2018.03.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063765PMC
August 2018

Traumatic Brain Injury and Infectious Encephalopathy in Children From Four Resource-Limited Settings in Africa.

Pediatr Crit Care Med 2018 07;19(7):649-657

Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA.

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http://dx.doi.org/10.1097/PCC.0000000000001554DOI Listing
July 2018

Variation in mortality rates after admission to long-term acute care hospitals for ventilator weaning.

J Crit Care 2018 08 23;46:6-12. Epub 2018 Mar 23.

CRISMA Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States; Department of Health Policy & Management, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, United States.

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http://dx.doi.org/10.1016/j.jcrc.2018.03.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014911PMC
August 2018

Referral Regions for Time-Sensitive Acute Care Conditions in the United States.

Ann Emerg Med 2018 08 29;72(2):147-155. Epub 2018 Mar 29.

Clinical Research, Investigation and Systems Modeling of Acute Illness Center, and the Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA; Department of Health Policy and Management, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA.

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http://dx.doi.org/10.1016/j.annemergmed.2018.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977951PMC
August 2018

Hospital Variation in Risk-Adjusted Pediatric Sepsis Mortality.

Pediatr Crit Care Med 2018 05;19(5):390-396

CRISMA Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1097/PCC.0000000000001502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935525PMC
May 2018

24 vs. 72 hours of hypothermia for pediatric cardiac arrest: A pilot, randomized controlled trial.

Resuscitation 2018 05 14;126:14-20. Epub 2018 Feb 14.

Critical Care Medicine, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA; Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA; Safar Center for Resuscitation Research, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.resuscitation.2018.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899619PMC
May 2018

Enhancing Recovery From Sepsis: A Review.

JAMA 2018 01;319(1):62-75

The Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2017.17687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839473PMC
January 2018

Postsepsis Morbidity.

JAMA 2018 01;319(1):91

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http://dx.doi.org/10.1001/jama.2017.19809DOI Listing
January 2018

Using incentives to recruit physicians into behavioral trials: lessons learned from four studies.

BMC Res Notes 2017 Dec 28;10(1):776. Epub 2017 Dec 28.

The Dartmouth Institute, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.

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http://dx.doi.org/10.1186/s13104-017-3101-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745997PMC
December 2017

Critical Care Organizations: Building and Integrating Academic Programs.

Crit Care Med 2018 04;46(4):e334-e341

Jay B. Langner Critical Care System, Montefiore Medical Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY.

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http://dx.doi.org/10.1097/CCM.0000000000002917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851809PMC
April 2018

Transportation characteristics associated with non-arrivals to paediatric clinic appointments: a retrospective analysis of 51 580 scheduled visits.

BMJ Qual Saf 2018 06 24;27(6):437-444. Epub 2017 Nov 24.

Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1136/bmjqs-2017-007168DOI Listing
June 2018

The Paradox of End-of-Life Hospital Treatment Intensity among Black Patients: A Retrospective Cohort Study.

J Palliat Med 2018 01 6;21(1):69-77. Epub 2017 Nov 6.

4 Department of Health Care Policy and Management, University of Pittsburgh Graduate School of Public Health , Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1089/jpm.2016.0557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757087PMC
January 2018